{"title":"对含有磷酸钙颗粒的实验性复合材料进行为期一年的钙释放监测。","authors":"Handially Vilela, Mariana Nakamura, Roberto Braga","doi":"10.2340/biid.v12.44586","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Ca<sup>2+</sup> release from specimens made of a composite containing dicalcium phosphate dihydrate particles (CaHPO<sub>4</sub>.2H<sub>2</sub>O, dicalcium phosphate dihydrate [DCPD]) was followed during 1 year.</p><p><strong>Methods: </strong>Specimens were individually immersed in deionized water (<i>n</i> = 3). Every 2 weeks, immersion medium was collected and specimens were transferred to new vials with fresh medium. Ca<sup>2+</sup> release was quantified using induced coupled plasma-optical emission spectrometry (ICP-OES). Data were analyzed by ANOVA/Tukey test (alpha: 5%).</p><p><strong>Results: </strong>Ca<sup>2+</sup> release was observed during the entire 12-month period. Cumulative release was 1635.1 ± 145.3 μg/cm<sup>2</sup> (179.7 ± 16.0 ppm), corresponding to 23.8 ± 2.0% of the total Ca mass in the specimen.</p><p><strong>Conclusion: </strong>The tested composite was capable of sustained Ca<sup>2+</sup> release in water for 1 year. In spite of the limitations of this screening test, the results suggest that composites containing Calcium phosphate (CaP) particles could offer a long-term Ca<sup>2+</sup> supply to the adjacent dental tissues.</p>","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"12 ","pages":"44586"},"PeriodicalIF":0.0000,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12406745/pdf/","citationCount":"0","resultStr":"{\"title\":\"One year monitoring of calcium release from an experimental composite containing calcium phosphate particles.\",\"authors\":\"Handially Vilela, Mariana Nakamura, Roberto Braga\",\"doi\":\"10.2340/biid.v12.44586\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Ca<sup>2+</sup> release from specimens made of a composite containing dicalcium phosphate dihydrate particles (CaHPO<sub>4</sub>.2H<sub>2</sub>O, dicalcium phosphate dihydrate [DCPD]) was followed during 1 year.</p><p><strong>Methods: </strong>Specimens were individually immersed in deionized water (<i>n</i> = 3). Every 2 weeks, immersion medium was collected and specimens were transferred to new vials with fresh medium. Ca<sup>2+</sup> release was quantified using induced coupled plasma-optical emission spectrometry (ICP-OES). Data were analyzed by ANOVA/Tukey test (alpha: 5%).</p><p><strong>Results: </strong>Ca<sup>2+</sup> release was observed during the entire 12-month period. Cumulative release was 1635.1 ± 145.3 μg/cm<sup>2</sup> (179.7 ± 16.0 ppm), corresponding to 23.8 ± 2.0% of the total Ca mass in the specimen.</p><p><strong>Conclusion: </strong>The tested composite was capable of sustained Ca<sup>2+</sup> release in water for 1 year. In spite of the limitations of this screening test, the results suggest that composites containing Calcium phosphate (CaP) particles could offer a long-term Ca<sup>2+</sup> supply to the adjacent dental tissues.</p>\",\"PeriodicalId\":72378,\"journal\":{\"name\":\"Biomaterial investigations in dentistry\",\"volume\":\"12 \",\"pages\":\"44586\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-08-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12406745/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biomaterial investigations in dentistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2340/biid.v12.44586\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomaterial investigations in dentistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2340/biid.v12.44586","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
One year monitoring of calcium release from an experimental composite containing calcium phosphate particles.
Introduction: Ca2+ release from specimens made of a composite containing dicalcium phosphate dihydrate particles (CaHPO4.2H2O, dicalcium phosphate dihydrate [DCPD]) was followed during 1 year.
Methods: Specimens were individually immersed in deionized water (n = 3). Every 2 weeks, immersion medium was collected and specimens were transferred to new vials with fresh medium. Ca2+ release was quantified using induced coupled plasma-optical emission spectrometry (ICP-OES). Data were analyzed by ANOVA/Tukey test (alpha: 5%).
Results: Ca2+ release was observed during the entire 12-month period. Cumulative release was 1635.1 ± 145.3 μg/cm2 (179.7 ± 16.0 ppm), corresponding to 23.8 ± 2.0% of the total Ca mass in the specimen.
Conclusion: The tested composite was capable of sustained Ca2+ release in water for 1 year. In spite of the limitations of this screening test, the results suggest that composites containing Calcium phosphate (CaP) particles could offer a long-term Ca2+ supply to the adjacent dental tissues.
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