Antimicrobial stewardship & healthcare epidemiology : ASHE最新文献

{"title":"A multifaceted antimicrobial stewardship intervention to improve antibiotic utilization and prescribing for sinusitis in a large primary care network.","authors":"Mike Sportiello, Colin Samoriski, Christine Kim, Alexander Pomakov, Troy Anlage, Ankit Dahal, Lauraliz Delacruz, Jonathan Gigas, Jenny Kim, Paulina Sudnik, Alison Livada, Monica Masterson, Charles Springer, John Bennett, Samia Lopa, Jineane Venci, Robert J Fortuna, Alexandra Yamshchikov","doi":"10.1017/ash.2026.10751","DOIUrl":"10.1017/ash.2026.10751","url":null,"abstract":"<p><p>A quality improvement project was implemented across a large primary care network to decrease antibiotic use and improve guideline-concordant therapy for acute sinusitis. The multifaceted intervention included education, EHR decision support, and individual prescriber feedback with peer comparison. The program was associated with improvements in guideline-concordant prescribing.</p>","PeriodicalId":72246,"journal":{"name":"Antimicrobial stewardship & healthcare epidemiology : ASHE","volume":"6 1","pages":"e175"},"PeriodicalIF":0.0,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13312255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Entrustable professional activities: a roadmap for infectious diseases fellowship training in antibiotic stewardship.","authors":"Reinaldo Perez, Molly McDonough, Eileen Maziarz, Rebekah H Wrenn, Rebekah Moehring","doi":"10.1017/ash.2026.10767","DOIUrl":"10.1017/ash.2026.10767","url":null,"abstract":"<p><p>Infectious diseases fellowship programs for physicians seek to train the next generation of leaders in antimicrobial stewardship, but few published resources are available to guide educational experiences. As an adaptable tool for training programs, we created a list of entrustable professional activities and suggested tasks to achieve competency during fellowship.</p>","PeriodicalId":72246,"journal":{"name":"Antimicrobial stewardship & healthcare epidemiology : ASHE","volume":"6 1","pages":"e188"},"PeriodicalIF":0.0,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13312247/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Penicillin allergy labels and antibiotic prescribing in carceral settings: expanding evidence from a statewide cohort.","authors":"Kap Sum Foong, Samuel Wilk, Rachel Tam, Lindsay Taylor, Alysse Wurcel","doi":"10.1017/ash.2026.10768","DOIUrl":"10.1017/ash.2026.10768","url":null,"abstract":"","PeriodicalId":72246,"journal":{"name":"Antimicrobial stewardship & healthcare epidemiology : ASHE","volume":"6 1","pages":"e186"},"PeriodicalIF":0.0,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13312235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing antibiotic prophylaxis in the surgical setting of an ambulatory hospital for patients with penicillin allergy labels: a quality improvement initiative.","authors":"Cassandra Elias, Hazra Chowdhury, Rebecca Wright, Ashley Graham, Karen Devon, Arun Prasad, Lisa Lin, Cameron Thomas, Mira Maximos","doi":"10.1017/ash.2026.10762","DOIUrl":"10.1017/ash.2026.10762","url":null,"abstract":"<p><p>At a Canadian ambulatory hospital, a quasi-experimental quality improvement initiative evaluated penicillin-allergy education modules using pre-post surveys. Among 61 clinicians, Module 1 was not associated with change in penicillin allergy label-clinical impact knowledge. Modules 2 and 3 improved allergy-history, severity-assessment, and prophylaxis-prescribing preparedness (<i>P</i> < .01). Acceptability was high: documentation tool 92%, algorithm 88%.</p>","PeriodicalId":72246,"journal":{"name":"Antimicrobial stewardship & healthcare epidemiology : ASHE","volume":"6 1","pages":"e185"},"PeriodicalIF":0.0,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13312242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overuse of a molecular infectious diarrhea panel in acute care: an opportunity for diagnostic stewardship.","authors":"Bushra Alhothli, Michael Payne, Aleksandra Stefanovic, Victor Leung, Christopher F Lowe, Patrick Tang, Marc G Romney, Nancy Matic","doi":"10.1017/ash.2026.10753","DOIUrl":"10.1017/ash.2026.10753","url":null,"abstract":"<p><p>A retrospective review of infectious diarrhea panel (IDP) utilization identified 62% of orders were non-adherent to clinical guidelines. Guideline-discordant orders were significantly less likely to (1) test positive for any target or (2) have impact on patient care. Improving IDP ordering for value-based healthcare is an important diagnostic stewardship intervention.</p>","PeriodicalId":72246,"journal":{"name":"Antimicrobial stewardship & healthcare epidemiology : ASHE","volume":"6 1","pages":"e187"},"PeriodicalIF":0.0,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13312241/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infection prevention and control of <i>Candida auris</i> in pediatric settings.","authors":"Thomas S Murray, Hana Hakim, Christelle Ilboudo, Lynn Ramírez-Ávila, Jana Shaw, Terri Stillwell, Patricia Budo, Bernard Ebruke, Noa Fleiss, Amanda Green, Matthew Linam, Roshni Mathew, April McDougal, Natalie Neu, Zoi Dorothea Pana, Karen Ravin, Ayelet Rosenthal, Jane D Siegel, Katlyn Steimel, Amy Valencia, Carol Vance, Lars F Westblade, Lisa Saiman","doi":"10.1017/ash.2026.10419","DOIUrl":"10.1017/ash.2026.10419","url":null,"abstract":"<p><strong>Background: </strong><i>Candida auris</i> (also referred to as <i>Candidozyma auris</i>) is an emerging multidrug-resistant fungal pathogen associated with high morbidity and mortality. Existing infection prevention and control (IPC) guidance has largely focused on adult populations, with limited recommendations for pediatric healthcare and non-healthcare settings.</p><p><strong>Methods: </strong>The Society for Healthcare Epidemiology of America (SHEA) convened a multidisciplinary expert panel to develop IPC recommendations for <i>C. auris</i>. The panel developed recommendations using a structured, iterative Delphi consensus process with rounds of discussion, refinement, and anonymous electronic voting with predefined consensus thresholds. Panelists reviewed relevant peer-reviewed and gray literature integrated with expert judgment and practical considerations. Preambles and remarks provide additional context and guidance.</p><p><strong>Results: </strong>This consensus statement provides recommendations for prevention of <i>C. auris</i> in pediatric acute care settings, non-acute healthcare settings, and non-healthcare congregate settings. Recommendations incorporate pediatric risk factors and care and address screening practices, isolation precautions, caregiver-infant/child dyad considerations, room placement and rooming in, breastfeeding and skin-to-skin practices, visitation, use of shared spaces, environmental cleaning and disinfection, and management of medical and non-medical equipment, including toys. Recommendations emphasize coordination with local infection prevention and public health partners.</p><p><strong>Conclusions: </strong>This SHEA consensus statement addresses gaps in pediatric-specific IPC guidance for <i>C. auris</i>. The recommendations provide a practical framework to support prevention of transmission within the context of pediatric clinical, developmental, and family-centered care.</p>","PeriodicalId":72246,"journal":{"name":"Antimicrobial stewardship & healthcare epidemiology : ASHE","volume":"6 1","pages":"e183"},"PeriodicalIF":0.0,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13312240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Provider report cards as a scalable tool for outpatient antibiotic stewardship: insights from a medicaid claims-based approach.","authors":"Mariana M Lanata, Jacob T Kilgore, Brandi Holthaus, Jonathan M Willis, Tess Anderson, Caroline B Samples, Jennifer Sparks, Joseph E Evans, Michael J Smith","doi":"10.1017/ash.2026.10752","DOIUrl":"10.1017/ash.2026.10752","url":null,"abstract":"<p><p>Antibiotic overprescribing remains common in pediatric outpatient care. We evaluated Medicaid claims-based provider report cards as a scalable stewardship tool. Quarterly audit and feedback improved guideline concordance, diagnostic appropriateness, and reduced cefdinir use; highlighting claims-based electronic feedback as a sustainable outpatient antimicrobial stewardship strategy suitable for statewide implementation.</p>","PeriodicalId":72246,"journal":{"name":"Antimicrobial stewardship & healthcare epidemiology : ASHE","volume":"6 1","pages":"e184"},"PeriodicalIF":0.0,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13312243/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the impact of antimicrobial stewardship in low-income healthcare settings: a study of antibiotic use and antimicrobial susceptibility patterns in Indian hospitals.","authors":"Ulhas Vasave, Amit Paroha","doi":"10.1017/ash.2026.10430","DOIUrl":"10.1017/ash.2026.10430","url":null,"abstract":"<p><strong>Objective: </strong>The rising incidence of antimicrobial resistance (AMR) underscores the urgent need for effective antimicrobial stewardship (AMS). This study assessed the impact of a tailored AMS initiative in Indian hospitals.</p><p><strong>Methods: </strong>An AMS surveillance program was implemented across 11 Indian hospitals (January 2022-June 2023). The intervention (July 2022-June 2023) included hospital-specific antibiograms, antibiotic policy design and implementation, monitoring antibiotic consumption, and tracking multidrug-resistant organisms (MDROs). Hospital staff were trained, and compliance audits with feedback were conducted. Implementation followed the Model for Improvement methodology over 18 months.</p><p><strong>Results: </strong>AMS surveillance revealed significant improvement in AMS knowledge and practices from the baseline to the postintervention phase. Antibiotic compliance increased from a baseline of 10% to 71% across hospitals, reaching 73%-91% in the subsequent period. Surgical prophylaxis compliance improved substantially, particularly in hospitals with initially low adherence. Optimizations in antibiotic selection, dosing, duration, intravenous-to-oral switching, and de-escalation were also observed, resulting in significant compliance gains across all domains. Use of antibiotics classified by the World Health Organization as safer first-line options with a narrow spectrum increased, while use of second- and third-line antibiotics, including those with broader spectra and higher resistance risks, decreased, reflecting a shift toward safer prescribing practices. However, MDRO incidence rates remained variable across sites, showing room for improvement.</p><p><strong>Conclusion: </strong>Locally tailored AMS interventions within a structured quality improvement framework can establish sustainable practices to mitigate AMR. These findings demonstrate effective strategies for optimizing antibiotic use and provide valuable insights for broader implementation of AMS.</p>","PeriodicalId":72246,"journal":{"name":"Antimicrobial stewardship & healthcare epidemiology : ASHE","volume":"6 1","pages":"e181"},"PeriodicalIF":0.0,"publicationDate":"2026-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13312239/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Standardizing sterilization practices for surgical implants: insights from the Asia Safe Surgical Implant Consortium.","authors":"Wing Hong Seto, Patricia Ching, Anucha Apisarnthanarak","doi":"10.1017/ash.2026.10377","DOIUrl":"10.1017/ash.2026.10377","url":null,"abstract":"<p><strong>Objective: </strong>Hospital-acquired infections (HAIs) pose significant challenges in the Asia Pacific region, where disparities in healthcare infrastructure and inconsistent infection prevention protocols may exacerbate patient safety risks. A recent survey of healthcare facilities across ten Asia-Pacific countries identified substantial gaps in compliance with international guidelines for sterilizing surgical implants, indicating a need for educational initiatives to drive improvement.</p><p><strong>Methods: </strong>The Asia Safe Surgical Implant Consortium was established through collaboration among regional professional associations and met in Tokyo, Japan, to formulate consensus recommendations.</p><p><strong>Results: </strong>The consensus process incorporated diverse expert perspectives and current evidence, resulting in three foundational documents that addressed quality assurance in sterilization, standardized management of loaner and implantable devices, and the implementation of a robust sterilization recall policy. These recommendations emphasize the integrated use of physical, chemical, and biological indicators, thorough documentation, and timely communication to enhance sterilization practices. Ongoing regional collaboration, investment in resources, and professional development were identified as critical for achieving consistent adoption of best practices and improving surgical outcomes.</p><p><strong>Conclusions: </strong>The consortium's work provides a structured framework to support central sterile supply departments and elevate patient safety standards across the Asia Pacific region.</p>","PeriodicalId":72246,"journal":{"name":"Antimicrobial stewardship & healthcare epidemiology : ASHE","volume":"6 1","pages":"e180"},"PeriodicalIF":0.0,"publicationDate":"2026-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13312249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148354968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antimicrobial stewardship: coming to a community pharmacy near you? A cross-sectional study to understand the perspectives of pharmacists, prescribers and the public.","authors":"Bradley J Langford, Shankavi Vigneswaran, Nick Daneman, Rita Ha, Certina Ho, Lina Ko, Valerie Leung, Wendy Levinson, Mira Maximos, Kim Neudorf, Angeline Ng, John Papastergiou, Sumit Raybardhan, Kevin L Schwartz, Maureen Smith, Julia E Szymczak, Mina Tadrous, Kathy Tam, Daniel Warshafsky, Miranda So","doi":"10.1017/ash.2026.10410","DOIUrl":"10.1017/ash.2026.10410","url":null,"abstract":"<p><p>This survey of the public, pharmacists, and other healthcare professionals identified factors affecting implementation of antibiotic stewardship in Canadian community pharmacies. Lack of support from non-pharmacist healthcare providers and pharmacy leadership were common barriers. Facilitators included providers' perceived importance of antibiotic stewardship, pharmacists' role as educators, and potential for healthcare cost savings.</p>","PeriodicalId":72246,"journal":{"name":"Antimicrobial stewardship & healthcare epidemiology : ASHE","volume":"6 1","pages":"e178"},"PeriodicalIF":0.0,"publicationDate":"2026-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13273155/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148280091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}