Isaac Sears, Michel Davis, Kevin Gibas, Leonard Mermel, Daithi S Heffernan
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Antidepressants and antibiotic resistance in urine cultures: a cohort study.
In vitro evidence of antidepressant-driven antibiotic resistance has recently been described. In this retrospective cohort study, significant associations are identified between antidepressant use and antibiotic resistance on urine cultures taken in the Emergency Department. This epidemiologic data supports previous in vitro work and raises additional questions for further study.
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