Antimicrobial stewardship & healthcare epidemiology : ASHE最新文献

Striving for zero traditional and non-traditional healthcare-associated infections (HAI): a target, vision, or philosophy. 努力实现零传统和非传统医疗保健相关感染（HAI）：一个目标、愿景或理念。

Antimicrobial stewardship & healthcare epidemiology : ASHE Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.1017/ash.2025.10031

Jaffar A Al-Tawfiq

引用次数: 0

Canadian impact of CLSI aminoglycoside breakpoint changes for selected gram-negative bacteria. CLSI氨基糖苷断点变化对选定革兰氏阴性菌的加拿大影响。

Antimicrobial stewardship & healthcare epidemiology : ASHE Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.1017/ash.2025.10035

Ellen Germaine Avery, Taylor Laughlin, Kevin Brown, Larissa M Matukas, Elizabeth Leung

引用次数: 0

The implementation of complex infection control bundles to prevent colorectal surgical site infections: a survey of SHEA research network hospitals. 实施复杂感染控制束预防结直肠手术部位感染：SHEA研究网络医院调查。

Antimicrobial stewardship & healthcare epidemiology : ASHE Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.1017/ash.2025.183

Michael Moran, Michele L Zimbric, Michelle Schmitz, Nasia Safdar, Aurora Pop-Vicas

{"title":"The implementation of complex infection control bundles to prevent colorectal surgical site infections: a survey of SHEA research network hospitals.","authors":"Michael Moran, Michele L Zimbric, Michelle Schmitz, Nasia Safdar, Aurora Pop-Vicas","doi":"10.1017/ash.2025.183","DOIUrl":"10.1017/ash.2025.183","url":null,"abstract":"Background: Surgical site infections (SSI) result in significant patient morbidity and excess healthcare costs. Colorectal surgeries have the highest SSI risk, as they manipulate the organ with the largest endogenous bioburden. This risk can be mitigated through complex prevention bundles, shown effective at reducing SSI in multiple studies, although little is known about their \"real-world\" use.Methods: To obtain further insight into the implementation of SSI prevention bundles consisting of guideline-recommended infection control elements in colorectal surgery, we distributed a multiple-choice survey to the hospitals within the Society for Healthcare Epidemiology of America Research Network from November 2022 to December 2023.Results: A total of 42 (45%) hospitals completed the survey. The bundle elements most used were intravenous pre-operative antibiotic prophylaxis (88%) and skin prep with an alcohol-chlorhexidine solution (86%). Infection control elements of surgical closure such as glove change and separate instrument tray were reported by 67% and 64%, respectively. Combined oral antibiotics with mechanical bowel prep were reported by 52%. Less than 50% of hospitals reported consistent bundle audit and feedback to frontline surgical staff. The most persistent barriers to implementation were a general culture resistant to change (40%) and clinicians' lack of compliance with the institutional bundle (38%).Conclusions: Our study found significant variability in the implementation of bundles consisting of multiple infection control elements to prevent SSI in clinical practice. Further research is needed to determine the strategies most effective in optimizing high-fidelity adoption of complex prevention bundles and to study their effect on SSI in colorectal surgery.","PeriodicalId":72246,"journal":{"name":"Antimicrobial stewardship & healthcare epidemiology : ASHE","volume":"5 1","pages":"e144"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12224134/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Self-reported beta-lactam allergy, mislabeling and inappropriate antibiotic use: a study from South India. 自我报告的β -内酰胺过敏、标签错误和抗生素使用不当：来自南印度的一项研究

Antimicrobial stewardship & healthcare epidemiology : ASHE Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.1017/ash.2025.10049

Krishna Suresh, Vettakkara Kandy Muhammed Niyas, Sabeer Hameed, Parvathy Vijayamohan, Rajalakshmi Ananthanarayanan

引用次数: 0

Optimizing oral antibiotic prescribing at hospital discharge: a single center, quasi-experiment pilot study. 优化出院时的口服抗生素处方：一项单中心、准实验试点研究。

Antimicrobial stewardship & healthcare epidemiology : ASHE Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.1017/ash.2025.10061

Ahmad Aloufi, Calvin Ka-Fung Lo, Colin Lee, Adrianna Gunton, Victor Leung

引用次数: 0

Screening practices for antimicrobial-resistant organisms in a network of Canadian acute care hospitals. 加拿大急性护理医院网络中抗微生物药物耐药性生物的筛选实践。

Antimicrobial stewardship & healthcare epidemiology : ASHE Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.1017/ash.2024.385

Andrew Neitzel, Jessica J Bartoszko, Erin McGill, Maureen Buchanan-Chell, Jenine Leal, Robyn Mitchell, Stephanie Smith, Reena Titoria, Oliva Varsaneux, Charles Frenette

引用次数: 0

A comparative study of antimicrobial prescribing practices for common infectious syndromes among physicians and nurse practitioners in a safety-net hospital. 某安全网医院内科医生和执业护士对常见感染综合征的抗菌药物处方做法的比较研究。

Antimicrobial stewardship & healthcare epidemiology : ASHE Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.1017/ash.2025.10058

Aakash Balaji, Jessica Hua, Ben Pomerantz, Alfredo J Mena Lora

引用次数: 0

An exploratory cost-effectiveness analysis of methicillin-resistant Staphylococcus aureus nares PCR in pediatric pneumonia and tracheitis. 耐甲氧西林金黄色葡萄球菌PCR治疗小儿肺炎和气管炎的探索性成本-效果分析

Antimicrobial stewardship & healthcare epidemiology : ASHE Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.1017/ash.2025.10043

Evan E Facer, Zachary Aldewereld, Michael D Green, Kenneth J Smith

{"title":"An exploratory cost-effectiveness analysis of methicillin-resistant Staphylococcus aureus nares PCR in pediatric pneumonia and tracheitis.","authors":"Evan E Facer, Zachary Aldewereld, Michael D Green, Kenneth J Smith","doi":"10.1017/ash.2025.10043","DOIUrl":"10.1017/ash.2025.10043","url":null,"abstract":"Objective: To estimate the cost-effectiveness of methicillin-resistant Staphylococcus aureus (MRSA) nares poymerase chain reaction (PCR) use in pediatric pneumonia and tracheitis.Methods: We built a cost-effectiveness model based on MRSA prevalence and probability of empiric treatment for MRSA pneumonia or tracheitis, with all parameters varied in sensitivity analyses. The hypothetical patient cohort was <18 years of age and hospitalized in the pediatric intensive care unit for community-acquired pneumonia (CAP) or tracheitis. Two strategies were compared: MRSA nares PCR-guided antibiotic therapy versus usual care. The primary measure was cost per incorrect treatment course avoided. Length of stay and hospital costs unrelated to antibiotic costs were assumed to be the same regardless of PCR use. Both literature data and expert estimates informed sensitivity analysis ranges.Results: When estimating the health care system willingness-to-pay threshold for PCR testing as $140 (varied in sensitivity analyses) per incorrect treatment course avoided, reflecting estimated additional costs of MRSA targeted antibiotics, and MRSA nares PCR true cost as $64, PCR testing was generally favored if empiric MRSA treatment likelihood was >52%. PCR was not favored in some scenarios when simultaneously varying MRSA infection prevalence and likelihood of MRSA empiric treatment. Screening becomes less favorable as MRSA PCR cost increased to the highest range value of the parameter ($88). Individual variation of MRSA colonization rates over wide ranges (0% - 30%) had lesser effects on results.Conclusions: MRSA nares PCR use in hospitalized pediatric patients with CAP or tracheitis was generally favored when empiric MRSA empiric treatment rates are moderate or high.","PeriodicalId":72246,"journal":{"name":"Antimicrobial stewardship & healthcare epidemiology : ASHE","volume":"5 1","pages":"e139"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12224135/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing the burden of outpatient urinary tract infections in the United States: analysis of nationwide ambulatory data (2016-2019). 评估美国门诊尿路感染负担：2016-2019年全国门诊数据分析

Antimicrobial stewardship & healthcare epidemiology : ASHE Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.1017/ash.2025.10045

Sonali D Advani, Meghan E Luck, Rose Chang, Mei Sheng Duh, Raj Desai, Megan Pinaire, Daisy Liu, Wendy Y Cheng, Jeffrey J Ellis

引用次数: 0

Assessing insurance claims as a measure for outpatient antimicrobial stewardship. 评估保险索赔作为门诊抗菌药物管理措施。

Antimicrobial stewardship & healthcare epidemiology : ASHE Pub Date : 2025-06-30 eCollection Date: 2025-01-01 DOI: 10.1017/ash.2025.10042

Mariana M Lanata, Jacob T Kilgore, Brandi Holthaus, Jonathan M Willis, Tess Anderson, Borden Samples, Jennifer Sparks, Joseph E Evans, Bethany A Wattles, Michael J Smith

{"title":"Assessing insurance claims as a measure for outpatient antimicrobial stewardship.","authors":"Mariana M Lanata, Jacob T Kilgore, Brandi Holthaus, Jonathan M Willis, Tess Anderson, Borden Samples, Jennifer Sparks, Joseph E Evans, Bethany A Wattles, Michael J Smith","doi":"10.1017/ash.2025.10042","DOIUrl":"10.1017/ash.2025.10042","url":null,"abstract":"Objective: This study evaluated Medicaid claims (MC) data as a valid source for outpatient antimicrobial stewardship programs (ASPs) by comparing it to electronic medical record (EMR) data from a single academic center.Methods: This retrospective study compared pediatric patients' MC data with EMR data from the Marshall Health Network (MHN). Claims were matched to EMR records based on patient Medicaid ID, service date, and provider NPI number. Demographics, antibiotic choice, diagnosis appropriateness, and guideline concordance were assessed across both data sources.Setting: The study was conducted within the MHN, involving multiple pediatric and family medicine outpatient practices in West Virginia, USA.Patients: Pediatric patients receiving care within MHN with Medicaid coverage.Results: MC and EMR data showed >90% agreement in antibiotic choice, gender, and date of service. Discrepancies were observed in diagnoses, especially for visits with multiple infectious diagnoses. MC data demonstrated similar accuracy to EMR data in identifying inappropriate prescriptions and assessing guideline concordance. Additionally, MC data provided timely information, enhancing the feasibility of impactful outpatient ASP interventions.Conclusion: MC data is a valid and timely resource for outpatient ASP interventions. Insurance providers should be leveraged as key partners to support large-scale outpatient stewardship efforts.","PeriodicalId":72246,"journal":{"name":"Antimicrobial stewardship & healthcare epidemiology : ASHE","volume":"5 1","pages":"e141"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12224133/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0