Advances in biochemical engineering/biotechnology最新文献

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Sulphidogenic Bioprocesses for Acid Mine Water Treatment and Selective Recovery of Arsenic and Metals. 用于酸性矿井水处理和砷与金属选择性回收的硫化生物工艺。
4区 工程技术
Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2024_264
Fabienne Battaglia-Brunet, Ivan Nancucheo, Jérôme Jacob, Catherine Joulian
{"title":"Sulphidogenic Bioprocesses for Acid Mine Water Treatment and Selective Recovery of Arsenic and Metals.","authors":"Fabienne Battaglia-Brunet, Ivan Nancucheo, Jérôme Jacob, Catherine Joulian","doi":"10.1007/10_2024_264","DOIUrl":"10.1007/10_2024_264","url":null,"abstract":"<p><p>Human communities need water and mineral resources, the supply of which requires the implementation of recycling and saving strategies. Both closed and active mining sites could beneficiate of the implementation of nature-based solutions, including bioreactors involving sulphate-reducing prokaryotes (SRP), in order to separate and recover arsenic (As) and metals from aqueous stream while producing clean water. Selective precipitation strategies can be designed based on the selection of microbial communities adapted to the pH conditions, generally acidic, and to available low-cost electron donors. Laboratory batch and continuous experiments must be implemented for each type of mine water in order to determine the optimal flow-sheet in which As could be precipitated as sulphides (orpiment or realgar), inside the bioreactor or offline, through stripping of biologically produced hydrogen sulphides (H<sub>2</sub>S). The respective concentrations and proportions of As and metals and the initial acid mine drainage pH are key parameters that will influence the feasibility of efficient selective precipitation. SRP-based bioreactors could be combined with complementary treatment steps in optimised mine water management solutions that will minimise the production of As-contaminated end-solid waste.</p>","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"1-30"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142071732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microalgae: A Biological Tool for Removal and Recovery of Potentially Toxic Elements in Wastewater Treatment Photobioreactors. 微藻:在废水处理中去除和回收潜在有毒元素的生物工具 光生物反应器。
4区 工程技术
Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2024_262
Beatriz Antolín Puebla, Marisol Vega Alegre, Silvia Bolado Rodríguez, Pedro A García Encina
{"title":"Microalgae: A Biological Tool for Removal and Recovery of Potentially Toxic Elements in Wastewater Treatment Photobioreactors.","authors":"Beatriz Antolín Puebla, Marisol Vega Alegre, Silvia Bolado Rodríguez, Pedro A García Encina","doi":"10.1007/10_2024_262","DOIUrl":"10.1007/10_2024_262","url":null,"abstract":"<p><p>Potentially toxic elements (PTE) pollution in water bodies is an emerging problem in recent decades due to uncontrolled discharges from human activities. Copper, zinc, arsenic, cadmium, lead, mercury, and uranium are considered potentially toxic and carcinogenic elements that threaten human health. Microalgae-based technologies for the wastewater treatment have gained importance in recent years due to their biomass high growth rates and effectiveness. Also, these microalgae-bacteria systems are cost-effective and environmentally friendly, utilize sunlight and CO<sub>2</sub>, and simultaneously address multiple environmental challenges, such as carbon mitigation, bioremediation, and generation of valuable biomass useful for biofuel production. Additionally, microalgae possess a diverse array of extracellular and intracellular mechanisms that enable them to remove and mitigate the toxicity of PTE present in wastewater. Therefore, photobioreactors are promising candidates for practical applications in bioremediation of wastewater containing toxic elements. Despite the increasing amount of research in this field in recent years, most studies are conducted in laboratory scale and there is a scarcity of large-scale studies under real and variable environmental conditions. Besides, the limited understanding of the multiple mechanisms controlling PTE biosorption in wastewater containing high organic matter loads and potentially toxic elements requires further studies. This chapter provides a schematic representation of the mechanisms and factors involved in the remediation of potentially toxic elements by microalgae, as well as the main results obtained in recent years.</p>","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"147-180"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142071731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chimeric Protein Switch Biosensors. 嵌合蛋白开关生物传感器。
4区 工程技术
Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2023_241
Emma Campbell, Timothy Luxton, Declan Kohl, Sarah A Goodchild, Christoph Walti, Lars J C Jeuken
{"title":"Chimeric Protein Switch Biosensors.","authors":"Emma Campbell, Timothy Luxton, Declan Kohl, Sarah A Goodchild, Christoph Walti, Lars J C Jeuken","doi":"10.1007/10_2023_241","DOIUrl":"10.1007/10_2023_241","url":null,"abstract":"<p><p>Rapid detection of protein and small-molecule analytes is a valuable technique across multiple disciplines, but most in vitro testing of biological or environmental samples requires long, laborious processes and trained personnel in laboratory settings, leading to long wait times for results and high expenses. Fusion of recognition with reporter elements has been introduced to detection methods such as enzyme-linked immunoassays (ELISA), with enzyme-conjugated secondary antibodies removing one of the many incubation and wash steps. Chimeric protein switch biosensors go further and provide a platform for homogenous mix-and-read assays where long wash and incubation steps are eradicated from the process. Chimeric protein switch biosensors consist of an enzyme switch (the reporter) coupled to a recognition element, where binding of the analyte results in switching the activity of the reporter enzyme on or off. Several chimeric protein switch biosensors have successfully been developed for analytes ranging from small molecule drugs to large protein biomarkers. There are two main formats of chimeric protein switch biosensor developed, one-component and multi-component, and these formats exhibit unique advantages and disadvantages. Genetically fusing a recognition protein to the enzyme switch has many advantages in the production and performance of the biosensor. A range of immune and synthetic binding proteins have been developed as alternatives to antibodies, including antibody mimetics or antibody fragments. These are mainly small, easily manipulated proteins and can be genetically fused to a reporter for recombinant expression or manipulated to allow chemical fusion. Here, aspects of chimeric protein switch biosensors will be reviewed with a comparison of different classes of recognition elements and switching mechanisms.</p>","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"1-35"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139562686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Imprinted Polymers on the Route to Plastibodies for Biomacromolecules (MIPs), Viruses (VIPs), and Cells (CIPs). 用于生物大分子(MIPs)、病毒(VIP)和细胞(CIPs)的质体抗体途径上的印迹聚合物。
4区 工程技术
Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2023_234
Xiaorong Zhang, Aysu Yarman, Mahdien Bagheri, Ibrahim M El-Sherbiny, Rabeay Y A Hassan, Sevinc Kurbanoglu, Armel Franklin Tadjoung Waffo, Ingo Zebger, Tutku Ceren Karabulut, Frank F Bier, Peter Lieberzeit, Frieder W Scheller
{"title":"Imprinted Polymers on the Route to Plastibodies for Biomacromolecules (MIPs), Viruses (VIPs), and Cells (CIPs).","authors":"Xiaorong Zhang, Aysu Yarman, Mahdien Bagheri, Ibrahim M El-Sherbiny, Rabeay Y A Hassan, Sevinc Kurbanoglu, Armel Franklin Tadjoung Waffo, Ingo Zebger, Tutku Ceren Karabulut, Frank F Bier, Peter Lieberzeit, Frieder W Scheller","doi":"10.1007/10_2023_234","DOIUrl":"10.1007/10_2023_234","url":null,"abstract":"<p><p>Around 30% of the scientific papers published on imprinted polymers describe the recognition of proteins, nucleic acids, viruses, and cells. The straightforward synthesis from only one up to six functional monomers and the simple integration into a sensor are significant advantages as compared with enzymes or antibodies. Furthermore, they can be synthesized against toxic substances and structures of low immunogenicity and allow multi-analyte measurements via multi-template synthesis. The affinity is sufficiently high for protein biomarkers, DNA, viruses, and cells. However, the cross-reactivity of highly abundant proteins is still a challenge.</p>","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"107-148"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54227354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent Developments and Applications of Microbial Electrochemical Biosensors. 微生物电化学生物传感器的最新发展和应用。
4区 工程技术
Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2023_236
Nunzio Giorgio G Carducci, Sunanda Dey, David P Hickey
{"title":"Recent Developments and Applications of Microbial Electrochemical Biosensors.","authors":"Nunzio Giorgio G Carducci, Sunanda Dey, David P Hickey","doi":"10.1007/10_2023_236","DOIUrl":"10.1007/10_2023_236","url":null,"abstract":"<p><p>This chapter provides a comprehensive overview of microbial electrochemical biosensors, which are a unique class of biosensors that utilize the metabolic activity of microorganisms to convert chemical signals into electrical signals. The principles and mechanisms of these biosensors are discussed, including the different types of microorganisms that can be used. The various applications of microbial electrochemical biosensors in fields such as environmental monitoring, medical diagnostics, and food safety are also explored. The chapter concludes with a discussion of future research directions and potential advancements in the field of microbial electrochemical biosensors.</p>","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"149-183"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139562789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Signal-Amplified Nanobiosensors for Virus Detection Using Advanced Nanomaterials. 利用先进纳米材料检测病毒的信号放大纳米生物传感器
4区 工程技术
Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2023_244
Akhilesh Babu Ganganboina, Enoch Y Park
{"title":"Signal-Amplified Nanobiosensors for Virus Detection Using Advanced Nanomaterials.","authors":"Akhilesh Babu Ganganboina, Enoch Y Park","doi":"10.1007/10_2023_244","DOIUrl":"10.1007/10_2023_244","url":null,"abstract":"<p><p>Rapid diagnosis and treatment of infectious illnesses are crucial for clinical outcomes and public health. Biosensing developments enhance diagnostics at the point of care. This is superior to traditional procedures, which need centralized lab facilities, specialized personnel, and large equipment. The emerging coronavirus epidemic threatens global health and economic security. Increasing viral surveillance and regulatory actions against disease transmission necessitate rapid, sensitive testing tools for viruses. Due to their sensitivity and specificity, biosensors offer a possible reliable and quantifiable viral detection method. Current advances in genetic engineering, such as genetic alteration and material engineering, have provided several opportunities to enhance biosensors' sensitivity, selectivity, and recognition efficiency. This chapter explains biosensing techniques, biosensor varieties, and signal amplification technologies. Challenges and potential developments for viral microorganisms based on biosensors and signal amplification were also investigated.</p>","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"381-412"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139711173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disposable Bioreactors Used in Process Development and Production Processes with Plant Cell and Tissue Cultures. 用于植物细胞和组织培养工艺开发和生产过程的一次性生物反应器。
4区 工程技术
Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2024_249
Rüdiger W Maschke, Stefan Seidel, Lia Rossi, Dieter Eibl, Regine Eibl
{"title":"Disposable Bioreactors Used in Process Development and Production Processes with Plant Cell and Tissue Cultures.","authors":"Rüdiger W Maschke, Stefan Seidel, Lia Rossi, Dieter Eibl, Regine Eibl","doi":"10.1007/10_2024_249","DOIUrl":"10.1007/10_2024_249","url":null,"abstract":"<p><p>The bioreactor is the centerpiece of the upstream processing in any biotechnological production process. Its design, the cultivation parameters, the production cell line, and the culture medium all have a major influence on the efficiency of the process and the result of the cultivation. Disposable bioreactors have been used for the past 20 years, playing a major role in process development and commercial production of high-value substances at medium scales.Our review deals with scalable, disposable bioreactors that have proven to be useful for the cultivation of plant cell and tissue cultures. Based on the definitions of terms and a categorization approach, the most commonly used, commercially available, disposable bioreactor types are presented below. The focus is on wave-mixed, stirred, and orbitally shaken bioreactors. In addition to their instrumentation and bioengineering characteristics, cultivation results are discussed, and emerging trends for the development of disposable bioreactors for plant cell and tissue cultures are also addressed.</p>","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"119-144"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140304361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Production of Plant Proteins and Peptides with Pharmacological Potential. 生产具有药用潜力的植物蛋白和肽。
4区 工程技术
Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2023_246
Jutta Ludwig-Müller
{"title":"Production of Plant Proteins and Peptides with Pharmacological Potential.","authors":"Jutta Ludwig-Müller","doi":"10.1007/10_2023_246","DOIUrl":"10.1007/10_2023_246","url":null,"abstract":"<p><p>The use of plant proteins or peptides in biotechnology is based on their identification as possessing bioactive potential in plants. This is usually the case for antimicrobial, fungicidal, or insecticidal components of the plant's defense system. They function in addition to a large number of specialized metabolites. Such proteins can be classified according to their sequence, length, and structure, and this has been tried to describe for a few examples here. Even though such proteins or peptides can be induced during plant-pathogen interaction, they are still present in rather small amounts that make the system not suitable for the production in large-scale systems. Therefore, a suitable type of host needs to be identified, such as cell cultures or adult plants. Bioinformatic predictions can also be used to add to the number of bioactive sequences. Some problems that can occur in production by the plant system itself will be discussed, such as choice of promoter for gene expression, posttranslational protein modifications, protein stability, secretion of proteins, or induction by elicitors. Finally, the plant needs to be set up by biotechnological or molecular methods for production, and the product needs to be enriched or purified. In some cases of small peptides, a direct chemical synthesis might be feasible. Altogether, the process needs to be considered marketable.</p>","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"51-81"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139574301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Applications of Gold Nanoparticles in Plasmonic and Nanophotonic Biosensing. 金纳米粒子在等离子和纳米光子生物传感中的应用。
4区 工程技术
Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2023_237
Kimberly Hamad-Schifferli
{"title":"Applications of Gold Nanoparticles in Plasmonic and Nanophotonic Biosensing.","authors":"Kimberly Hamad-Schifferli","doi":"10.1007/10_2023_237","DOIUrl":"10.1007/10_2023_237","url":null,"abstract":"<p><p>The unique properties of plasmonic nanoparticles and nanostructures have enabled a broad range of applications in a diverse set of fields, ranging from biological sensing, cancer therapy, to catalysis. They have been some of the most studied nanomaterials due in part to their chemical stability and biocompatibility as well as supporting theoretical efforts. The synthesis and fabrication of plasmonic nanoparticles and nanostructures have now reached high precision and sophistication. We review here their fundamental optical properties, discuss their tailoring for biological environments, and then detail examples on how they have been used to innovate in the biological and biomedical fields.</p>","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"185-221"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11182655/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139562684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Applications of Graphene Field Effect Biosensors for Biological Sensing. 石墨烯场效应生物传感器在生物传感方面的应用。
4区 工程技术
Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2024_252
Kiana Aran, Brett Goldsmith, Maryam Moarefian
{"title":"Applications of Graphene Field Effect Biosensors for Biological Sensing.","authors":"Kiana Aran, Brett Goldsmith, Maryam Moarefian","doi":"10.1007/10_2024_252","DOIUrl":"10.1007/10_2024_252","url":null,"abstract":"<p><p>This chapter provides a comprehensive overview of the principles, applications, and advancements in graphene field-effect transistor (gFET) biosensors for biological sensing. The unique properties of graphene that make it ideal for biosensing, including its high conductivity, chemical stability, and ability to facilitate label-free detection, will be discussed. The chapter also explores various applications of gFET biosensors, from detecting pH and salinity changes to complex protein-protein interactions and DNA/RNA sensing. It also addresses the challenges and future directions in gFET biosensor technology, emphasizing the need for scalable manufacturing, sophisticated surface chemistry, and the integration of multiomics approaches to enhance biosensing capabilities.</p>","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"37-70"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139989002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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