Advances in biochemical engineering/biotechnology最新文献_第5页

Plant In Vitro Culture Factories for Pentacyclic Triterpenoid Production. 生产五环三萜类化合物的植物体外培养工厂。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2023_245

Ilian Badjakov, Ivayla Dincheva, Radka Vrancheva, Vasil Georgiev, Atanas Pavlov

{"title":"Plant In Vitro Culture Factories for Pentacyclic Triterpenoid Production.","authors":"Ilian Badjakov, Ivayla Dincheva, Radka Vrancheva, Vasil Georgiev, Atanas Pavlov","doi":"10.1007/10_2023_245","DOIUrl":"10.1007/10_2023_245","url":null,"abstract":"Pentacyclic triterpenoids are a diverse subclass of naturally occurring terpenes with various biological activities and applications. These compounds are broadly distributed in natural plant resources, but their low abundance and the slow growth cycle of plants pose challenges to their extraction and production. The biosynthesis of pentacyclic triterpenoids occurs through two main pathways, the mevalonic acid (MVA) pathway and the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, which involve several enzymes and modifications. Plant in vitro cultures, including elicited and hairy root cultures, have emerged as an effective and sustainable system for pentacyclic triterpenoid production, circumventing the limitations associated with natural plant resources. Bioreactor systems and controlling key parameters, such as media composition, temperature, light quality, and elicitor treatments, have been optimized to enhance the production and characterization of specific pentacyclic triterpenoids. These systems offer a promising bioprocessing tool for producing pentacyclic triterpenoids characterized by a low carbon footprint and a sustainable source of these compounds for various industrial applications.","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"17-49"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139690959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biological Iron Removal and Recovery from Water and Wastewater. 从水和废水中生物除铁和回收。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2024_255

Anna Henriikka Kaksonen, Eberhard Janneck

{"title":"Biological Iron Removal and Recovery from Water and Wastewater.","authors":"Anna Henriikka Kaksonen, Eberhard Janneck","doi":"10.1007/10_2024_255","DOIUrl":"10.1007/10_2024_255","url":null,"abstract":"Iron is a common contaminant in source water and wastewater. The mining and metallurgical industries in particular can produce and discharge large quantities of wastewater with high iron concentrations. Due to the harmful effects of iron on organisms and infrastructure, efficient technologies for iron removal from water and wastewater are needed. On the other hand, iron is a valuable commodity for a wide range of applications. Microorganisms can facilitate iron removal and recovery through aerobic and anaerobic processes. The most commonly utilized microbes include iron oxidizers that facilitate iron precipitation as jarosites, schwertmannite, ferrihydrite, goethite, and scorodite, and sulfate reducers which produce hydrogen sulfide that precipitates iron as sulfides. Biological iron removal has been explored in various suspended cell and biofilm-based bioreactors that can be configured in parallel or series and integrated with precipitation and settling units for an effective flow sheet. This chapter reviews principles for biological iron removal and recovery, the microorganisms involved, reactor types, patents and examples of laboratory- and pilot-scale studies, and full-scale implementations of the technology.","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"31-88"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141475701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Progress on the Electrochemical Sensing of Illicit Drugs. 非法药物的电化学传感研究进展。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2023_239

Robin Van Echelpoel, Florine Joosten, Marc Parrilla, Karolien De Wael

引用次数: 0

Co-cultures from Plants and Cyanobacteria: A New Way for Production Systems in Agriculture and Bioprocess Engineering. 植物与蓝藻共培养：农业和生物加工工程生产系统的新途径。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2023_247

D Strieth, J Kollmen, J Stiefelmaier, A Mehring, R Ulber

{"title":"Co-cultures from Plants and Cyanobacteria: A New Way for Production Systems in Agriculture and Bioprocess Engineering.","authors":"D Strieth, J Kollmen, J Stiefelmaier, A Mehring, R Ulber","doi":"10.1007/10_2023_247","DOIUrl":"10.1007/10_2023_247","url":null,"abstract":"Due to the global increase in the world population, it is not possible to ensure a sufficient food supply without additional nitrogen input into the soil. About 30-50% of agricultural yields are due to the use of chemical fertilizers in modern times. However, overfertilization threatens biodiversity, such as nitrogen-loving, fast-growing species overgrow others. The production of artificial fertilizers produces nitrogen oxides, which act as greenhouse gases. In addition, overfertilization of fields also releases ammonia, which damages surface waters through acidification and eutrophication. Diazotrophic cyanobacteria, which usually form a natural, stable biofilm, can fix nitrogen from the atmosphere and release it into the environment. Thus, they could provide an alternative to artificial fertilizers. In addition to this, biofilms stabilize soils and thus protect against soil erosion and desiccation. This chapter deals with the potential of cyanobacteria as the use of natural fertilizer is described. Possible partners such as plants and callus cells and the advantages of artificial co-cultivation will be discussed later. In addition, different cultivation systems for studying artificial co-cultures will be presented. Finally, the potential of artificial co-cultures in the agar industry will be discussed.","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"83-117"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139574290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Solid-State Nanopores for Biomolecular Analysis and Detection. 用于生物分子分析和检测的固态纳米孔。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2023_240

Annina Stuber, Tilman Schlotter, Julian Hengsteler, Nako Nakatsuka

{"title":"Solid-State Nanopores for Biomolecular Analysis and Detection.","authors":"Annina Stuber, Tilman Schlotter, Julian Hengsteler, Nako Nakatsuka","doi":"10.1007/10_2023_240","DOIUrl":"10.1007/10_2023_240","url":null,"abstract":"Advances in nanopore technology and data processing have rendered DNA sequencing highly accessible, unlocking a new realm of biotechnological opportunities. Commercially available nanopores for DNA sequencing are of biological origin and have certain disadvantages such as having specific environmental requirements to retain functionality. Solid-state nanopores have received increased attention as modular systems with controllable characteristics that enable deployment in non-physiological milieu. Thus, we focus our review on summarizing recent innovations in the field of solid-state nanopores to envision the future of this technology for biomolecular analysis and detection. We begin by introducing the physical aspects of nanopore measurements ranging from interfacial interactions at pore and electrode surfaces to mass transport of analytes and data analysis of recorded signals. Then, developments in nanopore fabrication and post-processing techniques with the pros and cons of different methodologies are examined. Subsequently, progress to facilitate DNA sequencing using solid-state nanopores is described to assess how this platform is evolving to tackle the more complex challenge of protein sequencing. Beyond sequencing, we highlight the recent developments in biosensing of nucleic acids, proteins, and sugars and conclude with an outlook on the frontiers of nanopore technologies.","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"283-316"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139562792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sulphidogenic Bioprocesses for Acid Mine Water Treatment and Selective Recovery of Arsenic and Metals. 用于酸性矿井水处理和砷与金属选择性回收的硫化生物工艺。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2024_264

Fabienne Battaglia-Brunet, Ivan Nancucheo, Jérôme Jacob, Catherine Joulian

{"title":"Sulphidogenic Bioprocesses for Acid Mine Water Treatment and Selective Recovery of Arsenic and Metals.","authors":"Fabienne Battaglia-Brunet, Ivan Nancucheo, Jérôme Jacob, Catherine Joulian","doi":"10.1007/10_2024_264","DOIUrl":"10.1007/10_2024_264","url":null,"abstract":"Human communities need water and mineral resources, the supply of which requires the implementation of recycling and saving strategies. Both closed and active mining sites could beneficiate of the implementation of nature-based solutions, including bioreactors involving sulphate-reducing prokaryotes (SRP), in order to separate and recover arsenic (As) and metals from aqueous stream while producing clean water. Selective precipitation strategies can be designed based on the selection of microbial communities adapted to the pH conditions, generally acidic, and to available low-cost electron donors. Laboratory batch and continuous experiments must be implemented for each type of mine water in order to determine the optimal flow-sheet in which As could be precipitated as sulphides (orpiment or realgar), inside the bioreactor or offline, through stripping of biologically produced hydrogen sulphides (H2S). The respective concentrations and proportions of As and metals and the initial acid mine drainage pH are key parameters that will influence the feasibility of efficient selective precipitation. SRP-based bioreactors could be combined with complementary treatment steps in optimised mine water management solutions that will minimise the production of As-contaminated end-solid waste.","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"1-30"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142071732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microalgae: A Biological Tool for Removal and Recovery of Potentially Toxic Elements in Wastewater Treatment Photobioreactors. 微藻：在废水处理中去除和回收潜在有毒元素的生物工具光生物反应器。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2024_262

Beatriz Antolín Puebla, Marisol Vega Alegre, Silvia Bolado Rodríguez, Pedro A García Encina

{"title":"Microalgae: A Biological Tool for Removal and Recovery of Potentially Toxic Elements in Wastewater Treatment Photobioreactors.","authors":"Beatriz Antolín Puebla, Marisol Vega Alegre, Silvia Bolado Rodríguez, Pedro A García Encina","doi":"10.1007/10_2024_262","DOIUrl":"10.1007/10_2024_262","url":null,"abstract":"Potentially toxic elements (PTE) pollution in water bodies is an emerging problem in recent decades due to uncontrolled discharges from human activities. Copper, zinc, arsenic, cadmium, lead, mercury, and uranium are considered potentially toxic and carcinogenic elements that threaten human health. Microalgae-based technologies for the wastewater treatment have gained importance in recent years due to their biomass high growth rates and effectiveness. Also, these microalgae-bacteria systems are cost-effective and environmentally friendly, utilize sunlight and CO2, and simultaneously address multiple environmental challenges, such as carbon mitigation, bioremediation, and generation of valuable biomass useful for biofuel production. Additionally, microalgae possess a diverse array of extracellular and intracellular mechanisms that enable them to remove and mitigate the toxicity of PTE present in wastewater. Therefore, photobioreactors are promising candidates for practical applications in bioremediation of wastewater containing toxic elements. Despite the increasing amount of research in this field in recent years, most studies are conducted in laboratory scale and there is a scarcity of large-scale studies under real and variable environmental conditions. Besides, the limited understanding of the multiple mechanisms controlling PTE biosorption in wastewater containing high organic matter loads and potentially toxic elements requires further studies. This chapter provides a schematic representation of the mechanisms and factors involved in the remediation of potentially toxic elements by microalgae, as well as the main results obtained in recent years.","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"147-180"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142071731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chimeric Protein Switch Biosensors. 嵌合蛋白开关生物传感器。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2023_241

Emma Campbell, Timothy Luxton, Declan Kohl, Sarah A Goodchild, Christoph Walti, Lars J C Jeuken

{"title":"Chimeric Protein Switch Biosensors.","authors":"Emma Campbell, Timothy Luxton, Declan Kohl, Sarah A Goodchild, Christoph Walti, Lars J C Jeuken","doi":"10.1007/10_2023_241","DOIUrl":"10.1007/10_2023_241","url":null,"abstract":"Rapid detection of protein and small-molecule analytes is a valuable technique across multiple disciplines, but most in vitro testing of biological or environmental samples requires long, laborious processes and trained personnel in laboratory settings, leading to long wait times for results and high expenses. Fusion of recognition with reporter elements has been introduced to detection methods such as enzyme-linked immunoassays (ELISA), with enzyme-conjugated secondary antibodies removing one of the many incubation and wash steps. Chimeric protein switch biosensors go further and provide a platform for homogenous mix-and-read assays where long wash and incubation steps are eradicated from the process. Chimeric protein switch biosensors consist of an enzyme switch (the reporter) coupled to a recognition element, where binding of the analyte results in switching the activity of the reporter enzyme on or off. Several chimeric protein switch biosensors have successfully been developed for analytes ranging from small molecule drugs to large protein biomarkers. There are two main formats of chimeric protein switch biosensor developed, one-component and multi-component, and these formats exhibit unique advantages and disadvantages. Genetically fusing a recognition protein to the enzyme switch has many advantages in the production and performance of the biosensor. A range of immune and synthetic binding proteins have been developed as alternatives to antibodies, including antibody mimetics or antibody fragments. These are mainly small, easily manipulated proteins and can be genetically fused to a reporter for recombinant expression or manipulated to allow chemical fusion. Here, aspects of chimeric protein switch biosensors will be reviewed with a comparison of different classes of recognition elements and switching mechanisms.","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"1-35"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139562686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Imprinted Polymers on the Route to Plastibodies for Biomacromolecules (MIPs), Viruses (VIPs), and Cells (CIPs). 用于生物大分子（MIPs）、病毒（VIP）和细胞（CIPs）的质体抗体途径上的印迹聚合物。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2023_234

Xiaorong Zhang, Aysu Yarman, Mahdien Bagheri, Ibrahim M El-Sherbiny, Rabeay Y A Hassan, Sevinc Kurbanoglu, Armel Franklin Tadjoung Waffo, Ingo Zebger, Tutku Ceren Karabulut, Frank F Bier, Peter Lieberzeit, Frieder W Scheller

引用次数: 0

Recent Developments and Applications of Microbial Electrochemical Biosensors. 微生物电化学生物传感器的最新发展和应用。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2023_236

Nunzio Giorgio G Carducci, Sunanda Dey, David P Hickey

引用次数: 0