Advances in biochemical engineering/biotechnology最新文献

Environmental Sustainability of Cultivated Meat. 养殖肉类的环境可持续性。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2025-10-15 DOI: 10.1007/10_2025_293

Hanna L Tuomisto, Toni Ryynänen

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From Muscle Fibers to Functional Foods: Bridging Conventional and Cultivated Approaches. 从肌肉纤维到功能性食品：连接传统和人工方法。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2025-10-15 DOI: 10.1007/10_2025_290

Martin Krøyer Rasmussen, Rebekka Rinder Thøgersen, Jette Feveile Young, Margrethe Therkildsen

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Bioprocess Engineering for Cultivated Meat. 养殖肉类的生物工艺工程。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2025-10-15 DOI: 10.1007/10_2025_292

Julia Bernfeld, Simon Zschieschang, Marline Kirsch, Jordi Morales-Dalmau, Jasper Liedtke, Antonina Lavrentieva

{"title":"Bioprocess Engineering for Cultivated Meat.","authors":"Julia Bernfeld, Simon Zschieschang, Marline Kirsch, Jordi Morales-Dalmau, Jasper Liedtke, Antonina Lavrentieva","doi":"10.1007/10_2025_292","DOIUrl":"https://doi.org/10.1007/10_2025_292","url":null,"abstract":"Cultivated meat (CM) has emerged as a promising solution to the environmental, ethical, and food security concerns associated with conventional meat production. However, realising its full potential depends on developing robust, scalable, and cost-effective bioprocessing strategies. This chapter explores the entire CM bioprocessing pipeline, from upstream challenges such as the development of robust cell lines, scaling up cell cultures, and evaluating different operating modes like batch, fed-batch, and perfusion to downstream processes such as biomass harvesting, purification, and product structuring. Key considerations include ensuring sterility, monitoring critical process parameters, and supporting effective cell proliferation and differentiation. Economically, the high cost of media and capital expenditures remain a major barrier to scale. Strategies such as media recycling, bulk ingredient sourcing, and in-house production are being explored to reduce costs. Emerging technologies like artificial intelligence, machine learning, and digital twins offer new tools for optimising operations, though adoption is still in early stages. As the industry progresses toward commercialisation, continued innovation in bioprocess engineering, guided by techno-economic modelling, will be crucial to achieving scalable and sustainable meat alternatives.","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145290601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Correction to: The Human Gut Microbiota: A Dynamic Biologic Factory. 更正：人类肠道微生物群：动态生物工厂。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2025-01-01 DOI: 10.1007/10_2024_253

Alireza Minagar, Rabih Jabbour

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The Human Gut Microbiota: A Dynamic Biologic Factory. 人类肠道微生物群：动态生物工厂

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2025-01-01 DOI: 10.1007/10_2023_243

Alireza Minagar, Rabih Jabbour

{"title":"The Human Gut Microbiota: A Dynamic Biologic Factory.","authors":"Alireza Minagar, Rabih Jabbour","doi":"10.1007/10_2023_243","DOIUrl":"10.1007/10_2023_243","url":null,"abstract":"The human body constitutes a living environment for trillions of microorganisms, which establish the microbiome and, the largest population among them, reside within the gastrointestinal tract, establishing the gut microbiota. The term \"gut microbiota\" refers to a set of many microorganisms [mainly bacteria], which live symbiotically within the human host. The term \"microbiome\" means the collective genomic content of these microorganisms. The number of bacterial cells within the gut microbiota exceeds the host's cells; collectively and their genes quantitatively surpass the host's genes. Immense scientific research into the nature and function of the gut microbiota is unraveling its roles in certain human health activities such as metabolic, physiology, and immune activities and also in pathologic states and diseases. Interestingly, the microbiota, a dynamic ecosystem, inhabits a particular environment such as the human mouth or gut. Human microbiota can evolve and even adapt to the host's unique features such as eating habits, genetic makeup, underlying diseases, and even personalized habits. In the past decade, biologists and bioinformaticians have concentrated their research effort on the potential roles of the gut microbiome in the development of human diseases, particularly immune-mediated diseases and colorectal cancer, and have initiated the assessment of the impact of the gut microbiome on the host genome. In the present chapter, we focus on the biological features of gut microbiota, its physiology as a biological factory, and its impacts on the host's health and disease status.","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"91-106"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139711174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Selenium Removal from Wastewater by Microbial Transformation and Volatilization. 通过微生物转化和挥发去除废水中的硒。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2025-01-01 DOI: 10.1007/10_2023_242

Tochukwu Ekwonna, Olusegun Akindeju, Brianna Amos, Zhi-Qing Lin

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Mixed Culture Cultivation in Microbial Bioprocesses. 微生物生物工艺中的混合培养。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2025-01-01 DOI: 10.1007/10_2023_248

Manisha Khedkar, Dattatray Bedade, Rekha S Singhal, Sandip B Bankar

{"title":"Mixed Culture Cultivation in Microbial Bioprocesses.","authors":"Manisha Khedkar, Dattatray Bedade, Rekha S Singhal, Sandip B Bankar","doi":"10.1007/10_2023_248","DOIUrl":"10.1007/10_2023_248","url":null,"abstract":"Mixed culture cultivation is well renowned for industrial applications due to its technological and economic benefits in bioprocess, food processing, and pharmaceutical industries. A mixed consortium encompasses to achieve growth in unsterile conditions, robustness to environmental stresses, perform difficult functions, show better substrate utilization, and increase productivity. Hence, mixed cultures are being valorized currently and has also augmented our understanding of microbial activities in communities. This chapter covers a wide range of discussion on recent improvements in mixed culture cultivation for microbial bioprocessing and multifarious applications in different areas. The history of microbial culture, microbial metabolism in mixed culture, biosynthetic pathway studies, isolation and identification of strains, along with the types of microbial interactions involved during their production and propagation, are meticulously detailed in the current chapter. Besides, parameters for evaluating mixed culture performance, large-scale production, and challenges associated with it are also discussed vividly. Microbial community, characteristics of single and mixed culture fermentation, and microbe-microbe interactions in mixed cultures have been summarized comprehensively. Lastly, various challenges and opportunities in the area of microbial mixed culture that are obligatory to improve the current knowledge of microbial bioprocesses are projected.","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"9-69"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139989003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Investigation of Upgrading of Products from Finnoflag Bio-refinery Pilot in Tampere. 坦佩雷 Finnoflag 生物精炼厂试点产品升级调查。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2025-01-01 DOI: 10.1007/10_2024_261

Erik Dahlquist, Eva Thorin, Aubrey Shenk, Sebastian Schwede, Chaudhary Awais Salman, Elias Hakalehto

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Enzymes for Biomass Pretreatment: A Comprehensive Review. 生物质预处理用酶研究综述

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2025-01-01 DOI: 10.1007/10_2025_275

Runze Pan, Jingxiang Sun, Fengxue Xin, Wankui Jiang, Min Jiang

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Sustainable Approaches in Viticulture: From Wastes and Side Streams to High-Value Products. 葡萄栽培的可持续发展途径：从废料和侧流到高价值产品。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2025-01-01 DOI: 10.1007/10_2025_281

Niël van Wyk, Claudia Borgmeier, Alice Kleber, Esther M Gabor

{"title":"Sustainable Approaches in Viticulture: From Wastes and Side Streams to High-Value Products.","authors":"Niël van Wyk, Claudia Borgmeier, Alice Kleber, Esther M Gabor","doi":"10.1007/10_2025_281","DOIUrl":"10.1007/10_2025_281","url":null,"abstract":"In the context of climate change, resource scarcity, and a growing global population, sustainable processes and the efficient use of raw materials are imperative. Developing best practices to guide the transition toward a circular economy with minimized waste is essential. Agricultural processes offer inspiration, as they traditionally emphasize the utilization of all parts of cultivated plants. Today, however, there is a pressing need to go beyond basic utilization and focus on the upcycling and valorization of agricultural side streams into high-value products. This chapter examines the wine and grape industry, which generates substantial volumes of side streams, including grape pomace, seeds, stems, and wine lees. In recent years, these material streams have attracted attention for their potential as raw materials rich in bioactive compounds - such as diverse polyphenols, dietary fibers, and organic acids - that can be applied across various sectors, including food, cosmetics, pharmaceuticals, and bioenergy. Key methodologies such as extraction, fermentation, and bioconversion are discussed as pathways to recover and enhance these compounds. Case studies of successful valorization initiatives are presented, demonstrating practical applications of side streams for high-value product creation. An example is the BMBF-funded project \"Sustainable Beverages\" focusing on the development of fermented drinks made from vine leaves that can be offered as a non-alcoholic alternative to wine. By providing an overview of the current research and technologies in wine waste valorization, this chapter serves as a valuable resource for academics, industry professionals, and policymakers seeking to advance sustainable practices within the wine sector. Ultimately, the upcycling of wine industry residues not only reduces environmental impact but also creates new revenue opportunities, driving innovation and sustainability in the industry.","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"151-184"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143951854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0