Advances in biochemical engineering/biotechnology最新文献_第3页

Correction to: The Human Gut Microbiota: A Dynamic Biologic Factory. 更正：人类肠道微生物群：动态生物工厂。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2024-05-09 DOI: 10.1007/10_2024_253

Alireza Minagar, Rabih Jabbour

引用次数: 0

Mixed Culture Cultivation in Microbial Bioprocesses. 微生物生物工艺中的混合培养。

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Advances in biochemical engineering/biotechnology Pub Date : 2024-02-29 DOI: 10.1007/10_2023_248

Manisha Khedkar, Dattatray Bedade, Rekha S Singhal, Sandip B Bankar

{"title":"Mixed Culture Cultivation in Microbial Bioprocesses.","authors":"Manisha Khedkar, Dattatray Bedade, Rekha S Singhal, Sandip B Bankar","doi":"10.1007/10_2023_248","DOIUrl":"10.1007/10_2023_248","url":null,"abstract":"Mixed culture cultivation is well renowned for industrial applications due to its technological and economic benefits in bioprocess, food processing, and pharmaceutical industries. A mixed consortium encompasses to achieve growth in unsterile conditions, robustness to environmental stresses, perform difficult functions, show better substrate utilization, and increase productivity. Hence, mixed cultures are being valorized currently and has also augmented our understanding of microbial activities in communities. This chapter covers a wide range of discussion on recent improvements in mixed culture cultivation for microbial bioprocessing and multifarious applications in different areas. The history of microbial culture, microbial metabolism in mixed culture, biosynthetic pathway studies, isolation and identification of strains, along with the types of microbial interactions involved during their production and propagation, are meticulously detailed in the current chapter. Besides, parameters for evaluating mixed culture performance, large-scale production, and challenges associated with it are also discussed vividly. Microbial community, characteristics of single and mixed culture fermentation, and microbe-microbe interactions in mixed cultures have been summarized comprehensively. Lastly, various challenges and opportunities in the area of microbial mixed culture that are obligatory to improve the current knowledge of microbial bioprocesses are projected.","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139989003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Human Gut Microbiota: A Dynamic Biologic Factory. 人类肠道微生物群：动态生物工厂

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2024-02-10 DOI: 10.1007/10_2023_243

Alireza Minagar, Rabih Jabbour

{"title":"The Human Gut Microbiota: A Dynamic Biologic Factory.","authors":"Alireza Minagar, Rabih Jabbour","doi":"10.1007/10_2023_243","DOIUrl":"10.1007/10_2023_243","url":null,"abstract":"The human body constitutes a living environment for trillions of microorganisms, which establish the microbiome and, the largest population among them, reside within the gastrointestinal tract, establishing the gut microbiota. The term \"gut microbiota\" refers to a set of many microorganisms [mainly bacteria], which live symbiotically within the human host. The term \"microbiome\" means the collective genomic content of these microorganisms. The number of bacterial cells within the gut microbiota exceeds the host's cells; collectively and their genes quantitatively surpass the host's genes. Immense scientific research into the nature and function of the gut microbiota is unraveling its roles in certain human health activities such as metabolic, physiology, and immune activities and also in pathologic states and diseases. Interestingly, the microbiota, a dynamic ecosystem, inhabits a particular environment such as the human mouth or gut. Human microbiota can evolve and even adapt to the host's unique features such as eating habits, genetic makeup, underlying diseases, and even personalized habits. In the past decade, biologists and bioinformaticians have concentrated their research effort on the potential roles of the gut microbiome in the development of human diseases, particularly immune-mediated diseases and colorectal cancer, and have initiated the assessment of the impact of the gut microbiome on the host genome. In the present chapter, we focus on the biological features of gut microbiota, its physiology as a biological factory, and its impacts on the host's health and disease status.","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139711174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Selenium Removal from Wastewater by Microbial Transformation and Volatilization. 通过微生物转化和挥发去除废水中的硒。

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Advances in biochemical engineering/biotechnology Pub Date : 2024-02-10 DOI: 10.1007/10_2023_242

Tochukwu Ekwonna, Olusegun Akindeju, Brianna Amos, Zhi-Qing Lin

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Wearing the Lab: Advances and Challenges in Skin-Interfaced Systems for Continuous Biochemical Sensing. 穿戴实验室：用于连续生化传感的皮肤界面系统的进展与挑战。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2023_238

Zach Watkins, Adam McHenry, Jason Heikenfeld

{"title":"Wearing the Lab: Advances and Challenges in Skin-Interfaced Systems for Continuous Biochemical Sensing.","authors":"Zach Watkins, Adam McHenry, Jason Heikenfeld","doi":"10.1007/10_2023_238","DOIUrl":"10.1007/10_2023_238","url":null,"abstract":"Continuous, on-demand, and, most importantly, contextual data regarding individual biomarker concentrations exemplify the holy grail for personalized health and performance monitoring. This is well-illustrated for continuous glucose monitoring, which has drastically improved outcomes and quality of life for diabetic patients over the past 2 decades. Recent advances in wearable biosensing technologies (biorecognition elements, transduction mechanisms, materials, and integration schemes) have begun to make monitoring of other clinically relevant analytes a reality via minimally invasive skin-interfaced devices. However, several challenges concerning sensitivity, specificity, calibration, sensor longevity, and overall device lifetime must be addressed before these systems can be made commercially viable. In this chapter, a logical framework for developing a wearable skin-interfaced device for a desired application is proposed with careful consideration of the feasibility of monitoring certain analytes in sweat and interstitial fluid and the current development of the tools available to do so. Specifically, we focus on recent advancements in the engineering of biorecognition elements, the development of more robust signal transduction mechanisms, and novel integration schemes that allow for continuous quantitative analysis. Furthermore, we highlight the most compelling and promising prospects in the field of wearable biosensing and the challenges that remain in translating these technologies into useful products for disease management and for optimizing human performance.","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"223-282"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139562795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rationally Designed DNA-Based Scaffolds and Switching Probes for Protein Sensing. 合理设计用于蛋白质传感的 DNA 支架和切换探针。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2023_235

Alejandro Chamorro, Marianna Rossetti, Neda Bagheri, Alessandro Porchetta

{"title":"Rationally Designed DNA-Based Scaffolds and Switching Probes for Protein Sensing.","authors":"Alejandro Chamorro, Marianna Rossetti, Neda Bagheri, Alessandro Porchetta","doi":"10.1007/10_2023_235","DOIUrl":"10.1007/10_2023_235","url":null,"abstract":"The detection of a protein analyte and use of this type of information for disease diagnosis and physiological monitoring requires methods with high sensitivity and specificity that have to be also easy to use, rapid and, ideally, single step. In the last 10 years, a number of DNA-based sensing methods and sensors have been developed in order to achieve quantitative readout of protein biomarkers. Inspired by the speed, specificity, and versatility of naturally occurring chemosensors based on structure-switching biomolecules, significant efforts have been done to reproduce these mechanisms into the fabrication of artificial biosensors for protein detection. As an alternative, in scaffold DNA biosensors, different recognition elements (e.g., peptides, proteins, small molecules, and antibodies) can be conjugated to the DNA scaffold with high accuracy and precision in order to specifically interact with the target protein with high affinity and specificity. They have several advantages and potential, especially because the transduction signal can be drastically enhanced. Our aim here is to provide an overview of the best examples of structure switching-based and scaffold DNA sensors, as well as to introduce the reader to the rational design of innovative sensing mechanisms and strategies based on programmable functional DNA systems for protein detection.","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"71-106"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139562731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Resource-Efficient Use of Residues from Medicinal and Aromatic Plants for Production of Secondary Plant Metabolites. 资源高效利用药用和芳香植物残留物生产植物次生代谢物。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2024_250

Sibylle Kümmritz, Nanina Tron, Martin Tegtmeier, Axel Schmidt, Jochen Strube

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Plant In Vitro Culture Factories for Pentacyclic Triterpenoid Production. 生产五环三萜类化合物的植物体外培养工厂。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2023_245

Ilian Badjakov, Ivayla Dincheva, Radka Vrancheva, Vasil Georgiev, Atanas Pavlov

{"title":"Plant In Vitro Culture Factories for Pentacyclic Triterpenoid Production.","authors":"Ilian Badjakov, Ivayla Dincheva, Radka Vrancheva, Vasil Georgiev, Atanas Pavlov","doi":"10.1007/10_2023_245","DOIUrl":"10.1007/10_2023_245","url":null,"abstract":"Pentacyclic triterpenoids are a diverse subclass of naturally occurring terpenes with various biological activities and applications. These compounds are broadly distributed in natural plant resources, but their low abundance and the slow growth cycle of plants pose challenges to their extraction and production. The biosynthesis of pentacyclic triterpenoids occurs through two main pathways, the mevalonic acid (MVA) pathway and the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, which involve several enzymes and modifications. Plant in vitro cultures, including elicited and hairy root cultures, have emerged as an effective and sustainable system for pentacyclic triterpenoid production, circumventing the limitations associated with natural plant resources. Bioreactor systems and controlling key parameters, such as media composition, temperature, light quality, and elicitor treatments, have been optimized to enhance the production and characterization of specific pentacyclic triterpenoids. These systems offer a promising bioprocessing tool for producing pentacyclic triterpenoids characterized by a low carbon footprint and a sustainable source of these compounds for various industrial applications.","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"17-49"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139690959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Progress on the Electrochemical Sensing of Illicit Drugs. 非法药物的电化学传感研究进展。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2023_239

Robin Van Echelpoel, Florine Joosten, Marc Parrilla, Karolien De Wael

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Co-cultures from Plants and Cyanobacteria: A New Way for Production Systems in Agriculture and Bioprocess Engineering. 植物与蓝藻共培养：农业和生物加工工程生产系统的新途径。

4区工程技术

Advances in biochemical engineering/biotechnology Pub Date : 2024-01-01 DOI: 10.1007/10_2023_247

D Strieth, J Kollmen, J Stiefelmaier, A Mehring, R Ulber

{"title":"Co-cultures from Plants and Cyanobacteria: A New Way for Production Systems in Agriculture and Bioprocess Engineering.","authors":"D Strieth, J Kollmen, J Stiefelmaier, A Mehring, R Ulber","doi":"10.1007/10_2023_247","DOIUrl":"10.1007/10_2023_247","url":null,"abstract":"Due to the global increase in the world population, it is not possible to ensure a sufficient food supply without additional nitrogen input into the soil. About 30-50% of agricultural yields are due to the use of chemical fertilizers in modern times. However, overfertilization threatens biodiversity, such as nitrogen-loving, fast-growing species overgrow others. The production of artificial fertilizers produces nitrogen oxides, which act as greenhouse gases. In addition, overfertilization of fields also releases ammonia, which damages surface waters through acidification and eutrophication. Diazotrophic cyanobacteria, which usually form a natural, stable biofilm, can fix nitrogen from the atmosphere and release it into the environment. Thus, they could provide an alternative to artificial fertilizers. In addition to this, biofilms stabilize soils and thus protect against soil erosion and desiccation. This chapter deals with the potential of cyanobacteria as the use of natural fertilizer is described. Possible partners such as plants and callus cells and the advantages of artificial co-cultivation will be discussed later. In addition, different cultivation systems for studying artificial co-cultures will be presented. Finally, the potential of artificial co-cultures in the agar industry will be discussed.","PeriodicalId":7198,"journal":{"name":"Advances in biochemical engineering/biotechnology","volume":" ","pages":"83-117"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139574290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0