Yan Wang , Patricia A. Cavazos-Rehg , Yuxian Cui , Morgan Speer , Cassidy R. LoParco , Darcey M. McCready , Y. Tony Yang , Carla J. Berg
{"title":"The gateway effect of cigarette, e-cigarette, cigar, and alcohol use vs. Cannabis use","authors":"Yan Wang , Patricia A. Cavazos-Rehg , Yuxian Cui , Morgan Speer , Cassidy R. LoParco , Darcey M. McCready , Y. Tony Yang , Carla J. Berg","doi":"10.1016/j.addbeh.2025.108451","DOIUrl":"10.1016/j.addbeh.2025.108451","url":null,"abstract":"<div><h3>Background</h3><div>While the gateway hypothesis suggests that using tobacco and alcohol increases likelihood of initiating cannabis, cannabis use may precede and increase other substance use. We examined gateway effects of cigarettes, e-cigarettes, cigars, and alcohol on cannabis use, and reverse associations.</div></div><div><h3>Methods</h3><div>We analyzed 2023 survey data from 4,031 US young adults (M<sub>age</sub> = 26.29, 60 % female, 19 % Hispanic, 14 % Black, 14 % Asian). Discrete-time survival analysis assessed hazards of initiating cannabis based on self-reported age of initiating other substances, and vice versa. Time(age)-lagged predictors indicated whether participants had initiated the other substances by one year younger, accounting for sociodemographics; state non-medical cannabis laws; lifetime depression, anxiety, or attention deficit disorder [ADD]) diagnoses; and personality characteristics.</div></div><div><h3>Results</h3><div>Lifetime use was: 68 % for cannabis, 45 % cigarettes, 49 % e-cigarettes, 31 % cigars, and 85 % alcohol. Past-year cigarette, e-cigarette, cigar, and alcohol initiation increased hazards of initiating cannabis (adjusted Hazard Ratio, aHR = 3.78, 95 %CI = 3.39–4.22; aHR = 2.17, 95 %CI = 1.86–2.53; aHR = 2.90, 95 %CI = 2.45–3.43; aHR = 3.41, 95 %CI = 3.11–3.75, respectively). Past-year cannabis initiation increased hazards of other substance initiation (cigarettes: aHR = 3.51, 95 %CI = 3.11–3.96; e-cigarettes: aHR = 3.73, 95 %CI = 3.34–4.17; cigars: aHR = 3.66, 95 %CI = 3.20–4.18; alcohol: aHR = 3.07, 95 %CI = 2.73–3.45). Associations were generally stronger when initiation occurred at ages 5–18 vs. > 18. Depression predicted cannabis initiation; anxiety and ADD predicted e-cigarette initiation. Certain personality characteristics were protective against initiation (agreeableness and conscientiousness for each, openness for cigarettes and cigars, emotional stability for cannabis, cigarettes, and cigars); extraversion increased hazards of initiating cannabis and e-cigarettes.</div></div><div><h3>Conclusions</h3><div>Interventions should target underlying mechanisms influencing the use of various substances, such as mental health and personality characteristics, especially among adolescents.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"170 ","pages":"Article 108451"},"PeriodicalIF":3.6,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144810442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A longitudinal investigation of sports betting legalization’s influence on problem gambling","authors":"Tiange Xu , Joshua B. Grubbs , Shane W. Kraus","doi":"10.1016/j.addbeh.2025.108448","DOIUrl":"10.1016/j.addbeh.2025.108448","url":null,"abstract":"<div><div>As sports betting legalization expands across the United States, understanding its effects on problem gambling remains crucial for evidence-based policy development. This longitudinal study tracked 112 American sports bettors over two years using a natural experimental design, comparing problem gambling severity between participants in states that legalized sports betting during the study period versus those in states maintaining prohibitions. Mixed-effects negative binomial regression revealed no significant interaction between time and legalization status. However, equivalence testing failed to demonstrate that legalization’s effect was practically negligible, leaving the true impact uncertain. Demographic analysis identified significant risk factors, with younger age and single marital status predicting higher problem gambling severity. These findings underscore the need for targeted protective measures for vulnerable demographic groups within regulatory frameworks in newly legalized jurisdictions.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"170 ","pages":"Article 108448"},"PeriodicalIF":3.6,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144771562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vitoria B. Spinola , Jill M. Singer , Elizabeth G. Klein , Theodore L. Wagener , Marielle C. Brinkman , Alayna P. Tackett , Bo Lu , Dylan D. Wagner , Loren E. Wold , Megan E. Roberts
{"title":"Longitudinal analysis of e-cigarette and cannabis dual use in an Ohio sample of adolescents and young adults","authors":"Vitoria B. Spinola , Jill M. Singer , Elizabeth G. Klein , Theodore L. Wagener , Marielle C. Brinkman , Alayna P. Tackett , Bo Lu , Dylan D. Wagner , Loren E. Wold , Megan E. Roberts","doi":"10.1016/j.addbeh.2025.108444","DOIUrl":"10.1016/j.addbeh.2025.108444","url":null,"abstract":"<div><div>Adolescents and young adults (AYA) who vape e-cigarettes are likely to use cannabis (“dual use”), but little research has examined factors influencing future use pattern-. Using longitudinal data from 551 Ohio AYA (aged 15–24) who reported past-3-month e-cigarette use, we explored associations between baseline dual use and continued e-cigarette and cannabis use one year later, adjusting for sociodemographic factors. At baseline, 42.3 % of participants reported past-30-day cannabis use, indicating a high prevalence of dual use within this sample. Logistic regressions revealed that past-30-day tobacco use predicted continued e-cigarette use (OR = 1.97), but dual use at baseline was not a significant predictor. However, baseline dual use (OR = 4.58), lifetime cannabis use (OR = 3.91), and Sexual and Gender Minority status (OR = 2.57) significantly predicted continued cannabis use. These findings highlight the importance of addressing dual use in prevention efforts, as dual use at baseline was a strong predictor of continued cannabis use one year later—particularly among historically marginalized groups and those with prior cannabis exposure.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"170 ","pages":"Article 108444"},"PeriodicalIF":3.6,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144766435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tyler B. Mason , Dae-Hee Han , Melissa Wong , Dayoung Bae , Alyssa F. Harlow , Adam M. Leventhal
{"title":"Race and ethnicity differences in the association between the sensory experience and appeal of e-cigarette products: A pooled analysis of four within-subject experiments","authors":"Tyler B. Mason , Dae-Hee Han , Melissa Wong , Dayoung Bae , Alyssa F. Harlow , Adam M. Leventhal","doi":"10.1016/j.addbeh.2025.108447","DOIUrl":"10.1016/j.addbeh.2025.108447","url":null,"abstract":"<div><div>We pooled data from four product appeal testing experiments to examine whether associations of sensory attribute ratings (i.e., sweet, smooth, bitter, and harsh) of e-cigarettes with product appeal are moderated by race/ethnicity. Non-Hispanic White (<em>n</em> = 174), Black (<em>n</em> = 99), Asian (<em>n</em> = 34), Hispanic (<em>n</em> = 29), another race (<em>n</em> = 13), and multiracial (<em>n</em> = 56) adult tobacco product users completed product appeal testing. Participants self-administrated standardized doses of 8–40 different e-cigarette products (depending on the experiment) and rated the products’ sensory attributes and appeal. Multilevel models examined race/ethnicity as a moderator of the association of sensory attributes with appeal, using analyses partitioning between- and within-subjects variance. Product-specific (within-subjects) variance in sweetness was associated with enhanced e-cigarette appeal less strongly for Black vs. non-Hispanic White participants. Product-specific smoothness enhanced e-cigarette appeal more strongly for multiracial vs. non-Hispanic White participants. Product-specific bitterness reduced e-cigarette appeal more strongly for Hispanic vs. non-Hispanic White participants. Product-specific harshness reduced e-cigarette appeal and product-specific smoothness enhanced appeal less for Asian compared to non-Hispanic White participants. Regulatory restrictions on additives that suppress the harsh or bitter qualities of e-cigarettes may deter Hispanic adults from e-cigarettes but may be less likely to deter Asian adults. Black adults perceived appeal was less related to sweetness and thus may be more responsive to regulations outside of bans on sweet additives.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"170 ","pages":"Article 108447"},"PeriodicalIF":3.6,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144756845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katelyn Battista , Slim Haddad , Scott T. Leatherdale , Richard Bélanger
{"title":"Characteristics of adolescent cannabis use and social context predicting problematic use: A decision tree analysis","authors":"Katelyn Battista , Slim Haddad , Scott T. Leatherdale , Richard Bélanger","doi":"10.1016/j.addbeh.2025.108445","DOIUrl":"10.1016/j.addbeh.2025.108445","url":null,"abstract":"<div><div>Identifying characteristics of adolescent cannabis use and the surrounding social context that may predict problematic use is important for delivering harm-reduction approaches in both clinical and public health settings. We used a decision tree analysis to identify combinations of various use characteristics (e.g., frequency, mode, duration, initiation age, polysubstance use) and social context risk factors (e.g., peer and household use, solitary use, ease of access) characterizing the highest risk groups for three indicators of problematic use (unsuccessful quit attempt, excessive use, feeling addicted). We analyzed data from 8,915 cannabis ever-users from a large sample of secondary school students (mean age 15.5) in Québec, Canada, who completed the COMPASS survey. Using cannabis at least 2–4 times per month was the most important predictor of problematic use and independently characterized the highest risk groups. Initiating use before age 14 and engaging in solitary use also predicted increased problematic use risk among adolescents whose sustained past-year use did not meet the 2–4 times per month threshold. No sociodemographic differentiation emerged among high-risk groups. When screening for risky cannabis use or promoting safer cannabis behaviours among adolescents, health care providers and public health groups should consider factors with the greatest potential to influence detrimental trajectories among this age group.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"170 ","pages":"Article 108445"},"PeriodicalIF":3.6,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amy L. Gower , Ryan J. Watson , Lauren Love Pieczykolan , Marla E. Eisenberg
{"title":"The role of bias-based bullying in regular cannabis use among adolescents","authors":"Amy L. Gower , Ryan J. Watson , Lauren Love Pieczykolan , Marla E. Eisenberg","doi":"10.1016/j.addbeh.2025.108441","DOIUrl":"10.1016/j.addbeh.2025.108441","url":null,"abstract":"<div><div>Studies show bias-based bullying and harassment compromise health for youth with minoritized identities, and heavy/regular use of cannabis has implications for adolescent brain development. We examined how regular cannabis use varied by experiences of bullying based on sexual orientation, gender identity, and expression (SOGIE) or race and ethnicity, and social positions. Data came from 8th, 9th, and 11th graders completing the 2022 Minnesota Student Survey (N = 82,933). Students reported past 30 day cannabis use (3–5 times or more versus fewer/none), social positions (i.e., sexual, gender, racial, and ethnic identities, grade, access to resources), and race- and SOGIE-based bullying in the past 30 days (any versus none). Exhaustive Chi-square automatic interaction detection identified combinations of five social positions and bias-based bullying associated with the highest prevalences of regular cannabis use for each grade. Results indicated that across grades, cannabis use was 50–68 % lower among youth in social positions with the highest prevalence of frequent cannabis use when they were not the targets of bias-based bullying compared to youth with the same social positions who were targets of bias. For example, 18 % of 8th graders who had low access to resources; identified as American Indian, Alaska Native, or multiracial; and who experienced SOGIE-based bullying engaged in regular cannabis use, compared to 6.8 % prevalence for youth with the same identities who did not report bias-based bullying. Future research that examines bias-based bullying as a potential mechanism in adolescent cannabis use is warranted, particularly among youth with multiple minoritized identities.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"170 ","pages":"Article 108441"},"PeriodicalIF":3.6,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tingting Fang , Feng Zhuo , Xinran Xie , Ying Yang , Linghua Kong
{"title":"Unraveling the complexity of associations between problematic internet use, anxiety, and somatic symptoms in Chinese youth: a network perspective","authors":"Tingting Fang , Feng Zhuo , Xinran Xie , Ying Yang , Linghua Kong","doi":"10.1016/j.addbeh.2025.108438","DOIUrl":"10.1016/j.addbeh.2025.108438","url":null,"abstract":"<div><h3>Background</h3><div>Problematic Internet Use (PIU) is increasingly recognized as a significant public health concern among adolescents, often leading to anxiety symptoms and somatic symptoms. However, the underlying interrelationships between these symptom domains remain insufficiently understood, particularly at the symptom level.</div></div><div><h3>Methods</h3><div>This study applied network analysis to investigate the complexity of associations among PIU, anxiety, and somatic symptoms in a large, cross-sectional sample of 5221 adolescents aged 10–19 years from Shandong Province, China. Validated self-report instruments were used to assess PIU (IAT), anxiety (MASC), and somatic complaints (PHQ-13). Gaussian Graphical Models were constructed to identify central and bridge symptoms across the network, and sex differences were explored using the Network Comparison Test.</div></div><div><h3>Results</h3><div>The prevalence of PIU was 11.91%. Network analysis revealed dense interconnections among symptoms, with 64.7% of edges being non-zero. “Physical symptoms” of anxiety (MASC1) emerged as the most central and bridging symptom across the network, demonstrating the highest node strength and expected influence. The strongest edge linking PIU, anxiety, and somatic symptoms was between “physical symptoms” and “cannot breathe”. Although no significant gender differences were found in global network strength, the structure of symptom networks differed significantly between males and females. In males, the strongest bridge linked “time management & performance” with “sleep problems”, whereas in females, “withdrawal & social problems” was strongly linked to “indigestion symptoms”.</div></div><div><h3>Conclusions</h3><div>This study is the first to employ network analysis to map symptom-level associations between PIU, anxiety, and somatic symptoms in adolescents. The findings underscore the central role of anxiety-related physical symptoms in the network and highlight gender-specific symptom bridges. These insights offer novel directions for targeted interventions, emphasizing the need for symptom-focused and gender-sensitive treatment strategies for adolescents affected by PIU.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"170 ","pages":"Article 108438"},"PeriodicalIF":3.6,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144724415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peter R. Finn , Michael P. Smoker , Zachary W. Adams , Brigid R. Marriott , Eli J. Farmer , Leslie A. Hulvershorn
{"title":"Impulsive Decision Reduction Training (IDRT) reduces binge drinking and increases future orientation in young adult binge drinkers","authors":"Peter R. Finn , Michael P. Smoker , Zachary W. Adams , Brigid R. Marriott , Eli J. Farmer , Leslie A. Hulvershorn","doi":"10.1016/j.addbeh.2025.108443","DOIUrl":"10.1016/j.addbeh.2025.108443","url":null,"abstract":"<div><div>This paper introduces Impulsive Decision Reduction Training (IDRT) as a “proof of concept” in terms of its feasibility and preliminary outcome associations. IDRT is a novel, manualized, 8-week intervention designed to reduce impulsive and risky decisions regarding alcohol consumption and reduce excessive drinking. We conducted a pilot study of IDRT in young adult college students who binge drink, comparing IDRT with a waitlist control condition. Twenty-five participants (13 women, 12 men) completed the 8-week IDRT intervention and were compared with 20 (6 women and 14 men) who completed the assessments in the waitlist control group. IDRT was well-received (rated as very helpful), with all sessions attended, and only one IDRT participant dropping out after 3 sessions. Three waitlist control participants did not show up for the additional assessments after their initial baseline assessment. IDRT was associated with significant and large increases in future orientation and the consideration of the consequences of decisions (ps < 0.001). IDRT also associated with significant but modest reductions in the frequency of drinking (p < 0.05) and the maximum number of drinks consumed (p < 0.05), but not in the average quantity of alcohol consumed in an occasion or delay discounting rates, compared to a waitlist control condition. IDRT shows some initial promise as an intervention targeting reductions in impulsive and risky drinking decisions and reducing excessive drinking. Formal clinical trials should be conducted to more comprehensively assess the effectiveness of IDRT in reducing excessive drinking.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"170 ","pages":"Article 108443"},"PeriodicalIF":3.6,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144721513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elizabeth Moss-Alonso , Rubén Rodríguez-Cano , Carmela Martínez-Vispo , Ana López-Durán , Elisardo Becoña
{"title":"Prospective associations between smoking abstinence and anhedonia among people who seek smoking cessation treatment","authors":"Elizabeth Moss-Alonso , Rubén Rodríguez-Cano , Carmela Martínez-Vispo , Ana López-Durán , Elisardo Becoña","doi":"10.1016/j.addbeh.2025.108439","DOIUrl":"10.1016/j.addbeh.2025.108439","url":null,"abstract":"<div><h3>Introduction</h3><div>Depression has been broadly studied in association with tobacco smoking. However, little is known about the prospective association between anhedonia, one of the core symptoms of depression, and smoking outcomes after smoking cessation treatment. The goal of this study was to examine the bidirectional and longitudinal relation between anhedonia and smoking abstinence after smoking cessation intervention and up to a 12-month follow-up.</div></div><div><h3>Methods</h3><div>The sample was composed of 685 participants (Mage = 45.51; 62 % female) that were enrolled in three cognitive-behavioural smoking cessation interventions. Anhedonia and smoking abstinence were measured at post-treatment, and at 3-, 6- and 12-month follow-ups. The bidirectional and longitudinal association was analysed applying a Random Intercept Cross-Lagged Panel Model (RI-CLPM), and results were controlled for the effects of sex and differing studies.</div></div><div><h3>Results</h3><div>The RI-CLPM showed that smoking abstinence in one timepoint predicted lower anhedonia at the following timepoint for each assessment. Although greater anhedonia was related to lower smoking abstinence crossectionally at post-treatment, 6- and 12-month follow-ups, precedent anhedonia did not predict consequent smoking abstinence at any follow-up. The results were consistent when controlling potential confounding variables.</div></div><div><h3>Conclusions</h3><div>The bidirectional analysis indicated that smoking abstinence predicted lower anhedonia after a smoking cessation intervention during the course of 12 months, but anhedonia did not significantly predict smoking abstinence at any consequent timepoint. Findings have relevant implications as may serve to motivate healthcare professionals to apply tailored smoking cessation interventions, and people who smoke to quit due to the potential impact on mood.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"170 ","pages":"Article 108439"},"PeriodicalIF":3.7,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144696749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Melinda Mahabee-Gittens , Nicole Mack , Carla M. Bann , Jamie E. Newman , Junfang Zhao , Kenneth D.R. Setchell , Lara Stone , Namasivayam Ambalavanan , Myriam Peralta-Carcelen , Sara B. DeMauro , Scott A. Lorch , Deanne E. Wilson-Costello , Brenda B. Poindexter , Catherine Limperopoulos , Jonathan M. Davis , Stephanie L. Merhar
{"title":"Tobacco and cannabis use among pregnant women with prenatal opioid use","authors":"E. Melinda Mahabee-Gittens , Nicole Mack , Carla M. Bann , Jamie E. Newman , Junfang Zhao , Kenneth D.R. Setchell , Lara Stone , Namasivayam Ambalavanan , Myriam Peralta-Carcelen , Sara B. DeMauro , Scott A. Lorch , Deanne E. Wilson-Costello , Brenda B. Poindexter , Catherine Limperopoulos , Jonathan M. Davis , Stephanie L. Merhar","doi":"10.1016/j.addbeh.2025.108442","DOIUrl":"10.1016/j.addbeh.2025.108442","url":null,"abstract":"<div><h3>Background</h3><div>There is a paucity of information on tobacco and cannabis use patterns in pregnant women who use opioids. Our objective was to examine sociodemographic, tobacco, and cannabis use patterns during pregnancy among pregnant women with opioid use.</div></div><div><h3>Methods</h3><div>We recruited 206 pregnant women with biochemically verified opioid use during pregnancy, of whom 98 self-reported taking only medications for opioid use disorder (MOUD) and 108 reported taking other opioids during pregnancy. We examined sociodemographic characteristics and self-report of tobacco and cannabis use overall and by trimester. Chi-square and t-tests were used to assess differences between the MOUD-only vs other opioids groups. Logistic regression models were used to examine differences in factors associated with tobacco and cannabis use.</div></div><div><h3>Results</h3><div>Mean (SD) age was 30.7 years (4.6); 81.9 % were non-Hispanic White, and 92.6 % had public insurance. Of the 91 women taking MOUD only and completing the substance use self-report, 50 (54.9 %) reported tobacco use only, 3 (3.3 %) reported cannabis use only, and 24 (26.4 %) reported both tobacco and cannabis use. Tobacco and cannabis use was similar for women taking other opioids (p = 0.98). Adjusted odds ratios indicated that there was consistent use of all tobacco products (p = 0.28) including e-cigarette products (p = 0.18) throughout all 3 trimesters of pregnancy. There was decreased use of cannabis over the course of pregnancy with 29.8 % using cannabis during the first trimester and 16.5 % during the last trimester (p = 0.0003).</div></div><div><h3>Conclusions</h3><div>While we observed no differences in tobacco and cannabis use between those taking MOUD only versus other opioids, we observed high rates of tobacco and cannabis use among pregnant women with opioid use. These findings underscore the need for tobacco and cannabis use education and cessation interventions throughout pregnancy for those with OUD.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"170 ","pages":"Article 108442"},"PeriodicalIF":3.6,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144771561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}