Addictive behaviors最新文献

{"title":"The Cannabis Use Disorder Identification Test – Consumption (CUDIT-C) as a targeted tool for cannabis use screening","authors":"Margy Y. Chen ,&nbsp;Carillon J. Skrzynski ,&nbsp;L.Cinnamon Bidwell ,&nbsp;Angela D. Bryan","doi":"10.1016/j.addbeh.2025.108399","DOIUrl":"10.1016/j.addbeh.2025.108399","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to evaluate the psychometric properties and predictive utility of the Cannabis Use Disorders Identification Test – Consumption (CUDIT-C), a concise alternative to the Cannabis Use Disorders Identification Test – Revised (CUDIT-R), across individuals with differing levels of cannabis use.</div></div><div><h3>Method</h3><div>Participants included infrequent (<em>N</em> = 108) and frequent cannabis users (<em>N</em> = 138) from two studies. A confirmatory factor analysis (CFA) was first conducted to test a two-factor model of the CUDIT-R, hypothesizing that the first two items (CUDIT-C) load onto one factor, while the remaining items load onto a second factor related to cannabis dependence and problems. The CUDIT-C and CUDIT-R were then assessed for their ability to predict cannabis-related outcomes, including self-reported use days over the past 30 days and peak plasma delta-9-tetrahydrocannabinol (THC) levels following acute use.</div></div><div><h3>Results</h3><div>The two-factor model was a stronger fit to the data than the one-factor model. Among infrequent users, the CUDIT-C performed equivalently to the CUDIT-R. In frequent users, the CUDIT-C either matched or outperformed the CUDIT-R, including being a stronger predictor of peak THC levels, an established marker of hazardous cannabis exposure. Conclusion</div><div>The CUDIT-C is a practical and effective tool for assessing cannabis use, particularly among frequent users. However, its utility may be limited for infrequent users due to restricted variability of use in this group. Future research should explore its application in clinical settings and diverse populations, as well as its potential for diagnosing cannabis use disorders.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"169 ","pages":"Article 108399"},"PeriodicalIF":3.7,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144240209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A network perspective on heroin use: associations between craving, withdrawal symptoms, dependence, loss of control, and psychosocial consequences","authors":"Veronica Szpak ,&nbsp;Joji Suzuki ,&nbsp;Reinout W. Wiers ,&nbsp;René Freichel","doi":"10.1016/j.addbeh.2025.108400","DOIUrl":"10.1016/j.addbeh.2025.108400","url":null,"abstract":"<div><h3>Background</h3><div>Opioid use disorder (OUD) is a complex diagnosis characterized by symptoms such as craving, tolerance, withdrawal, and impaired social, occupational, or recreational activities. However, there is a lack of data about the interconnectedness of these symptoms, in particular the links between withdrawal symptoms and psychosocial impairment. The present study uses symptom network analysis to better understand these associations surrounding heroin use.</div></div><div><h3>Methods</h3><div>We used data from individuals who reported heroin use during the past 12 months in the National Survey on Drug Use and Health (NSDUH) (year 2021, n = 207). We estimated a cross-sectional network that included heroin use-related aspects, including coping and withdrawal symptoms, consequences, loss of control, craving, and dependence symptoms. To examine key ‘bridge nodes’ that connect these different clusters, we computed a measure of bridge expected influence for each node.</div></div><div><h3>Results</h3><div>The network model revealed several symptom connections within and between clusters. The withdrawal symptom, sleep problems, had the strongest bridge centrality. The dependence symptom “increased use for an effect”, was a key bridge node connecting to withdrawal symptoms and consequences. Craving was connected with two withdrawal symptoms (depressed mood and sweating). Additional symptom connections emerged between the loss of control and other dependence symptom nodes.</div></div><div><h3>Conclusions</h3><div>Our network analysis model provides additional insight into how heroin use symptoms and relevant characteristics are interconnected. Craving and loss of control (time spent using, amount of use) map onto specific withdrawal symptoms.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"169 ","pages":"Article 108400"},"PeriodicalIF":3.7,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144263940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The landscape of youth addiction in Israel: Identifying high-risk behaviors","authors":"Yaniv Efrati","doi":"10.1016/j.addbeh.2025.108396","DOIUrl":"10.1016/j.addbeh.2025.108396","url":null,"abstract":"<div><div>While significant progress has been made in understanding the prevalence of use and severity of addictive behaviors, there remains a lack of research adopting a lay epidemiological approach to examine a broad spectrum of addictive behaviors among a large youth population. The objective of this study is to investigate the frequencies of use and severity of various addictive-like behaviors across different demographic variables including gender, religion, country of birth, religiosity, socio-economic status, and age. The sample comprised 6,849 Jewish and Arabic Israeli youth from the general community, consisting of 2,776 males (41 %) and 4,074 females (59 %), 12–18 years of age (M = 15.92, SD = 1.27) who completed the survey anonymously and with parental consent. Results indicated that higher severity in one addictive behavior correlates with increased severity in others. Substance-related behaviors such as alcohol, tobacco, cannabis, and cocaine showed stronger correlations within their group than with behavioral addictions like gambling, shopping, gaming, eating disorders, sexual activity and social networking. Similarly, behavioral addictions also display stronger correlations within their own cluster. In addition, significant prevalence of use and severity differences were observed in addictive behaviors based on gender, religion, country of birth, religiosity, socio-economic status, and age. The research underscores the critical role of providing support and resources to youth, which is essential for preventing addictive behaviors and reducing the risks associated with their development.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"169 ","pages":"Article 108396"},"PeriodicalIF":3.7,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144229988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Daily patterns of single and poly-substance use among adolescent and young adult females: A day-level latent class analysis","authors":"Emily A. Doherty ,&nbsp;Susette A. Moyers ,&nbsp;Erica K. Crockett-Barbera ,&nbsp;Hannah Appleseth ,&nbsp;Quinn Leffingwell ,&nbsp;Veronica Richards ,&nbsp;Ashleigh L. Chiaf ,&nbsp;Julie M. Croff","doi":"10.1016/j.addbeh.2025.108394","DOIUrl":"10.1016/j.addbeh.2025.108394","url":null,"abstract":"<div><h3>Background</h3><div>Substance use is prevalent among adolescents and young adults (AYAs). Polysubstance use is associated with poorer outcomes than single substance use alone. However, few studies have examined patterns of daily use of substance(s) among AYA females, as well as associated factors.</div></div><div><h3>Objective</h3><div>We aimed to 1) identify daily substance use patterns in AYA females, and 2) examine the association with select predisposing factors (i.e. impulsivity and depressive symptoms) and risky sexual behavior.</div></div><div><h3>Method</h3><div>A sample of 15–24 year old females with recent binge drinking (n = 149), reported daily substance use and sexual activity through weekly Timeline Followback interviews over a 1-month period (n _days = 4224). Impulsivity, depressive symptoms, and sociodemographics were measured at baseline. Day-level latent class analysis was conducted to characterize patterns of substance use, and Bolck, Croon, and Hagenaars three-step approach was utilized to examine the association of predisposing factors and other health behaviors with latent class membership.</div></div><div><h3>Results</h3><div>Four day-level classes of substance use were identified: 1) little-to-no-use (54.1 % of days); 2) vaping-only (28.2 % of days); 3) cannabis-only (10.5 % of days); and 4) heavy-alcohol-and-cannabis (some smoking and vaping; 7.2 % of days). More class 4 days were associated with higher impulsivity than class 1 and 3 (M = 0.42 vs. −0.17 and −0.13), more depressive symptoms than class 1 and 2 (M = 0.77 vs. −0.19 and 0.01), and more same day condomless sex than class 1 and 2 (19 % vs. 8 % and 7 %).</div></div><div><h3>Conclusions</h3><div>AYA females exhibit varied patterns of daily substance use including polysubstance use. Knowledge of risk factors associated with problematic use as well as co-occurring risky sexual behavior can inform targeted intervention and prevention efforts.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"169 ","pages":"Article 108394"},"PeriodicalIF":3.7,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144221437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Problematic pornography use and psychological distress: A longitudinal study in a large US sample","authors":"Robin Engelhardt ,&nbsp;Rahel Geppert ,&nbsp;Joshua B. Grubbs ,&nbsp;Timo von Oertzen ,&nbsp;Dominik Trommer ,&nbsp;Jürgen Maes ,&nbsp;Shane W. Kraus","doi":"10.1016/j.addbeh.2025.108398","DOIUrl":"10.1016/j.addbeh.2025.108398","url":null,"abstract":"<div><div>Problematic pornography use (PPU) has been positively associated with psychological distress (i.e., anxiety and depression) in numerous cross-sectional studies. In the present study, we examined the trajectory of PPU and its association with psychological distress over time. We conducted a one-year, three-wave longitudinal study among US adults (<em>n</em> = 4363, 46.4 % women, M_(Age) = 50, <em>SD</em>_(Age) = 16.15) and examined changes in PPU and psychological distress. Specifically, we assessed bivariate correlations and a random-intercept autoregressive cross-lagged panel model. PPU was assessed by the Brief Pornography Screen (BPS), and psychological distress was assessed by the Generalized Anxiety Disorder–2 (GAD-2) and the Patient Health Questionnaire-9 (PHQ-9). Between each six-month period, we found that BPS bivariate intercorrelations were strong <em>(ρ</em> = 0.712, 0.726) and BPS autoregressive paths remained moderate (<em>β</em> = 0.370, 0.408). Surprisingly, the positive associations between BPS and psychological distress scores from descriptive correlations were determined by a strong random-intercept correlation (<em>r</em> = 0.962), while cross-lagged paths remained small and negative (<em>β=-0</em>.189, −0.211, −0.214, −0.230, respectively). This suggested a robust trait-like between-person association between PPU and psychological distress, with negligibly small time-dependent within-person inhibitory effects occurring. PPU appears time-consistent (e.g., most participants remained in their initial clinical category) and robustly associated with psychological distress over time. We speculate that inhibitory within-person effects may possibly reflect short-term coping behavior and depressive drive inhibition, while in the long term, further manifesting PPU.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"169 ","pages":"Article 108398"},"PeriodicalIF":3.7,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144229987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Illicit drug use and associated health risk behaviors among sexual minority youth","authors":"Jeffrey Duong ,&nbsp;Deirdra Kelly ,&nbsp;Andres F. Sciolla","doi":"10.1016/j.addbeh.2025.108397","DOIUrl":"10.1016/j.addbeh.2025.108397","url":null,"abstract":"<div><h3>Objective</h3><div>This study examined the links between lifetime illicit drug use (e.g., cocaine, hallucinogens, ecstasy, heroin) and proximal health risk behaviors among adolescents and investigated sexual identity as a moderator.</div></div><div><h3>Methods</h3><div>We analyzed data from the Center for Disease Control’s 2021 Youth Risk Behavior Survey (N = 17,232), a biennial, cross-sectional survey of a nationally representative sample of youth enrolled in grades 9 through 12 in the United States. Bivariate tabulations of weighted data were used to estimate the prevalence of health risk behaviors among lifetime illicit drug users and sexual minority youth who identified as lesbian, gay, bisexual, questioning, or another sexual identity (LGBQ+). Structural equation modeling was used to examine their associations. Wald testing was employed to test for effect modification.</div></div><div><h3>Results</h3><div>Illicit drug use was associated with a broad range of health risk behaviors among adolescents (e.g., cigarette and marijuana use, drinking and driving, use of alcohol and drugs before sex, and having multiple sex partners). There was a significant interaction between lifetime illicit drug use and sexual identity such that LGBQ+ youth who have ever engaged in illicit drug use had the greatest odds of health risk behaviors.</div></div><div><h3>Conclusions</h3><div>Adolescents with a history of ever using illicit drugs are likely to engage in a wide array of health risk behaviors. Screening and offering counseling on these health risk behaviors may play a crucial role in ensuring that the sequela of drug use among adolescents is minimized, especially for LGBQ+ youth.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"169 ","pages":"Article 108397"},"PeriodicalIF":3.7,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144212443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smoking cue reactivity and smoking motives in patients with early phase psychotic disorder","authors":"Marie-Eve Couture ,&nbsp;Sherry Stewart ,&nbsp;Sean Barrett ,&nbsp;Phil Tibbo ,&nbsp;Heather Milliken ,&nbsp;Maria Alexiadis ,&nbsp;Nancy Robertson ,&nbsp;Kimberley P. Good","doi":"10.1016/j.addbeh.2025.108392","DOIUrl":"10.1016/j.addbeh.2025.108392","url":null,"abstract":"<div><h3>Background</h3><div>Rates of tobacco smoking in individuals with psychosis are high and are unfortunately accompanied by low rates of successful smoking cessation. Exposure to smoking-related cues is shown to reliably enhance cigarette cravings in dependent people who smoke recruited from the general population. Recent data suggests that smoking-related cues do not affect people who smoke diagnosed with established schizophrenia to the same degree as non-psychotic populations. However, less is known about how individuals in the early phase of psychotic illness react to these cues. In addition, it is unknown whether the smoking motives of individuals with early phase psychosis (EPP) differ from those of non-psychotic individuals who smoke (NPS).</div></div><div><h3>Study design</h3><div>The present study compared cue-elicited cigarette cravings of EPP (n = 21, mean(sd) age27.6(7.8) years) to NPS (n = 40) in response to a smoking cue-reactivity paradigm and additionally, compared general self-reported motives for smoking across these groups.</div></div><div><h3>Study results</h3><div>Similar to those with established psychosis, EPP individuals were less sensitive to the cue-reactivity paradigm, suggesting that individuals in early phase of illness may not be affected by tobacco cues to the same degree as NPS. Further, comparison of smoking motives suggests no differences between the reasons for smoking reported by individuals with EPP and NPS.</div></div><div><h3>Conclusions</h3><div>These findings have implications for future studies aimed at identifying the source of the wide discrepancy in rates of tobacco smoking and smoking cessation across these two populations, and for the development of effective smoking cessation interventions for people who smoke with EPP.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"169 ","pages":"Article 108392"},"PeriodicalIF":3.7,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144212445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Untangling the role of emotion regulation in gambling and video gaming cravings: A replication and extension study","authors":"Francisco J. Rivero ,&nbsp;Juan Ramón Barrada ,&nbsp;Ismael Muela ,&nbsp;José C. Perales ,&nbsp;Jose López-Guerrero ,&nbsp;Juan F. Navas ,&nbsp;Elena-Aurora García-Gómez ,&nbsp;Damien Brevers ,&nbsp;Víctor Ciudad-Fernández","doi":"10.1016/j.addbeh.2025.108393","DOIUrl":"10.1016/j.addbeh.2025.108393","url":null,"abstract":"<div><h3>Background</h3><div>Existing evidence suggests that urgency—the tendency to act rashly under intense positive or negative affect—reflects dysregulated incidental emotion regulation (ER). Urgency has been reported to predict the intensity and frequency of video gaming and gambling craving, but not the translation of craving onto severity of problem symptoms. However, the role of intentional ER strategies, such as cognitive reappraisal and expressive suppression, in craving control remains underexplored.</div></div><div><h3>Method</h3><div>303 regular gamblers and 355 regular video gamers were assessed on urgency traits, ER strategies, self-reported craving, and gaming/gambling-related severity of problem symptoms. Using structural equation modeling (SEM), we tested hypotheses regarding: (1) the mediating role of craving in the relationship between positive/negative urgency and severity, and (2) the moderating role of ER strategies in the link between craving and severity.</div></div><div><h3>Results</h3><div>Results revealed that, in both activities, positive urgency—but not negative urgency—significantly predicted craving, replicating a positive urgency→craving→severity pathway. However, urgencies did not moderate the craving-severity relationship. Regarding intentional ER strategies, in the gaming sample, suppression moderated the association between craving and severity: cravings were more strongly associated with severity of problem symptoms in individuals more prone to use suppression. In the gambling sample, reappraisal moderated the impact of craving on severity: craving was less strongly associated with severity in individuals using reappraisal more often.</div></div><div><h3>Discussion</h3><div>These findings suggest that positive urgency operates similarly in gaming and gambling cravings, highlighting appetitive mechanisms in craving emergence. Intentional ER seems to influence severity in interaction with craving, with craving exerting a stronger impact on severity in individuals using less adaptive strategies.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"170 ","pages":"Article 108393"},"PeriodicalIF":3.7,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144298682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electroencephalography microstates predict 12-h abstinence-induced craving changes in young smokers","authors":"Fang Dong ,&nbsp;Zhimin Zhou ,&nbsp;Zhiwei Ren ,&nbsp;Yongxin Cheng ,&nbsp;Yuxin Ma ,&nbsp;Juan Wang ,&nbsp;Ting Xue ,&nbsp;Dahua Yu ,&nbsp;Gengdi Huang ,&nbsp;Kai Yuan ,&nbsp;Xiaoqi Lu","doi":"10.1016/j.addbeh.2025.108395","DOIUrl":"10.1016/j.addbeh.2025.108395","url":null,"abstract":"<div><div>Nicotine abstinence inhibits the function of the mesolimbic dopamine system to enhance craving. EEG microstates may provide spatiotemporal characteristics of global brain neuronal activity. However, little is known about the temporal dynamics and spatial topography of microstates in young smokers after abstinence. At the same time, in order to explore the neurophysiological mechanisms of craving induced by smoking abstinence, baseline microstates indicators were applied to predict craving changes. This study compared the microstates characteristics in 53 young male smokers and 48 matched nonsmokers. A 12-hour smoking abstinence procedure was designed for smokers, and their craving levels were measured using the Questionnaire on Smoking Urges (QSU). Furthermore, smokers were divided into high-craving and low-craving groups based on whether their craving changes increased after abstinence. We investigated the differences of microstates indicators before and after abstinence, and explored the relationships between baseline EEG microstates characteristics and smoking craving changes. The machine learning methods were used to predict abstinence-induced craving changes. We observed that the 12-h abstinence procedure significantly decreased the explained variance, duration, occurrence and coverage of microstates class D in 53 smokers. Craving changes induced by abstinence were significantly positively correlated with the explained variance, duration, occurrence and coverage of class D at baseline. The baseline microstates characteristics in smokers predicted abstinence-induced craving changes with an accuracy of 70.18%. These findings suggest that EEG microstates features can serve as key functional biomarkers for abstinence-induced craving in young smokers, providing novel insights for developing personalized abstinence intervention strategies based on EEG characteristics.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"169 ","pages":"Article 108395"},"PeriodicalIF":3.7,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144184548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global burden of disease related to tobacco products and trends projected: 1990–2021","authors":"Quanzheng Chen ,&nbsp;Chuan Zhang ,&nbsp;Fengjin Zhong,&nbsp;Yuxuan Huang,&nbsp;Yuanyu Zeng,&nbsp;Shuna Zhang","doi":"10.1016/j.addbeh.2025.108391","DOIUrl":"10.1016/j.addbeh.2025.108391","url":null,"abstract":"<div><h3>Background</h3><div>The use of tobacco products is considered to be one of the most serious public health threats worldwide, and this study aims to assess the global burden of various diseases caused by tobacco use, provide the necessary scientific basis for public health authorities, and propose tobacco control policies and interventions.</div></div><div><h3>Methods</h3><div>This study analyzed the major burden of disease caused by tobacco products using the Global Burden of Disease (GBD) database from 1990 to 2021. Age Standardization Rate (ASR), annual Percentage Change (EAPC) were calculated using R4.2.3 software. Disease burden prediction analysis with the help of BAPC and INLA software packages.</div></div><div><h3>Results</h3><div>The study findings indicated that from 1990 to 2021, the number of deaths and disability-adjusted life years (DALYs) attributable to tobacco products increased annually worldwide. Cardiovascular diseases and chronic respiratory diseases are the primary disease types caused by tobacco products, with the disease burden significantly higher in males than females. Significant disparities were observed between regions with different Socio-Demographic Index (SDI) levels. High SDI countries experienced more pronounced reductions in burden, whereas countries with low, middle, and middle-high SDI levels bore higher disease burdens. By 2040, the number of deaths and disease burden attributable to tobacco products globally is projected to continue increasing annually, albeit at a slower rate.</div></div><div><h3>Conclusion</h3><div>Despite a reduction in the global disease burden caused by tobacco, countries with low, middle, and middle-high SDI levels continue to bear a substantial burden.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"169 ","pages":"Article 108391"},"PeriodicalIF":3.7,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144124004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}