Addictive behaviors最新文献

{"title":"Latent transition analysis of use frequencies for multiple nicotine and tobacco products among US adults","authors":"Ritesh Mistry PhD ,&nbsp;Irina Bondarenko ,&nbsp;Jihyoun Jeon ,&nbsp;Andrew F. Brouwer ,&nbsp;Evelyn Jimenez Mendoza ,&nbsp;David T. Levy ,&nbsp;Michael R. Elliott ,&nbsp;Jamie Tam ,&nbsp;Nancy L. Fleischer ,&nbsp;Rafael Meza","doi":"10.1016/j.addbeh.2024.108217","DOIUrl":"10.1016/j.addbeh.2024.108217","url":null,"abstract":"<div><h3>Background</h3><div>Given the many nicotine and tobacco products in use, studies of the interdependence of use patterns and transitions are needed.</div></div><div><h3>Methods</h3><div>Using Waves 1–4 of the PATH Study, we analyzed latent transitions among adults who ever regularly used nicotine or tobacco products at Wave 1 to identify latent use states (n = 12,358) and estimated one-wave transition probabilities. Multinomial logistic regression identified demographic factors associated with transitions.</div></div><div><h3>Results</h3><div>We identified seven latent states: Non-current (42.5% in Wave 1); Daily Cigarette (29.7%); Non-daily Cigarette (9.8%); Daily Cigarette and Non-daily Polytobacco (DCNP, 7.4%), Daily Smokeless Tobacco (SLT, 4.9%); Non-daily Cigar (3.2%); and Daily ENDS (Electronic Nicotine Delivery Systems) and Non-daily Cigarette (DENC, 2.4%). Among Daily Cigarette, 93% did not transition, 2.2% transitioned to Non-daily cigarette, 1.7% to DENC, and 2.2% to Non-current. Among DENC, 87.4% did not transition, 7.3% transitioned to Daily Cigarette, and 3.8% to Non-current. Lower income was associated with lower odds of transitioning from Daily Cigarette and DCNP to Non-daily Cigarette and DENC use. Lower education was associated with higher odds of relapse. Non-Hispanic Blacks were more likely than Non-Hispanic Whites to transition from Daily Cigarette to DCNP and less likely to transition to DENC.</div></div><div><h3>Conclusions</h3><div>Most individuals remained in their latent use state. The polytobacco and non-daily use states were most likely to transition. Non-Hispanic Blacks were more likely to make harmful transitions, and lower socioeconomic status was associated with a lower probability of transitioning to less harmful states. These differences in transitions may influence tobacco- and nicotine-related health disparities.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"161 ","pages":"Article 108217"},"PeriodicalIF":3.7,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142756968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Qualitative interviews with young adults at risk for psychosis and who use Cannabis: Informing the development of a mobile intervention","authors":"Jennifer E. Merrill ,&nbsp;Ethan Moitra ,&nbsp;Kayla Giorlando ,&nbsp;Elizabeth M. Olsen ,&nbsp;Avery Leigland ,&nbsp;Ana M. Abrantes ,&nbsp;Laura Whiteley","doi":"10.1016/j.addbeh.2024.108216","DOIUrl":"10.1016/j.addbeh.2024.108216","url":null,"abstract":"<div><div>Cannabis use disorder is common among young adults in psychiatric care, particularly those at risk for psychosis. Yet, interventions tailored to address this issue are limited. The goal of this qualitative study was to determine barriers and facilitators for reducing/quitting cannabis use, and to obtain end-user perspectives to inform a mobile app-based intervention. Twenty young adults (60% female) at high-risk for psychosis who use cannabis completed a brief survey and individual qualitative interview. Results of thematic analysis revealed five barriers (i.e., cannabis to cope, social influences, dependence symptoms, easy access, ambivalence about change) and four facilitators (e.g., experienced/feared consequences, focusing on motivation, social support, coping skills) to cutting down/quitting cannabis. Regarding mobile intervention development, participants recommended high-level personalization and content features such as goal setting, self-monitoring, coping skills, and affirming messages. Additionally, they suggested the intervention be visually appealing and interactive. To assist high-risk youth in reducing/quitting cannabis use, it is important to consider the unique barriers they face in doing so, as well as their specific preferences for the development of a mobile intervention.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"161 ","pages":"Article 108216"},"PeriodicalIF":3.7,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142700968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cannabis use regimens in trauma-exposed individuals: Associations with cannabis use quantity and frequency","authors":"T. Snooks ,&nbsp;P.G. Tibbo ,&nbsp;P. Romero-Sanchiz ,&nbsp;S. DeGrace ,&nbsp;S.H. Stewart","doi":"10.1016/j.addbeh.2024.108203","DOIUrl":"10.1016/j.addbeh.2024.108203","url":null,"abstract":"<div><div>People with trauma histories have an increased odds of cannabis use. Little is known about the frequency or consequences of different cannabis use regimens in cannabis users with trauma histories. Individuals with anxiety disorders tend to administer benzodiazepines in a <em>pro re nata</em> (PRN; i.e., as needed) as opposed to regularly scheduled (RS, e.g., twice daily [BID], three times daily [TID]) manner. Although physicians tend to prescribe benzodiazepines on a PRN regimen to minimize use, this regimen is paradoxically associated with greater use levels. Indeed, PRN administration regimens may increase use via negative reinforcement processes. We extended this older benzodiazepine literature to cannabis by examining regimen of cannabis use among 94 trauma-exposed cannabis users (mean age = 35.1 years; 52.1 % male; 23.4 % with cannabis prescription). Participants reported their initial and current cannabis use regimen (PRN vs. RS vs. both [‘PRN+’]) and their past month cannabis use frequency (use occasions in last month) and quantity (grams/use occasion). Consistent with patterns in benzodiazepine research, PRN (47.1 % of sample) and PRN+ (43.5 % of sample) were more common than RS regimens (9.4 % of sample). Also consistent with patterns seen with benzodiazepines, our sample moved toward PRN regimens from initial to current use: e.g., 100 % of initial RS users switched to a regimen that included PRN use. Consistent with predictions emerging from learning theory, PRN and PRN+ cannabis users reported significantly higher cannabis use frequencies compared to RS users (<em>p</em>’s &lt; 0.01). Unexpectedly, there were no significant differences between cannabis use regimen groups for quantity of cannabis/occasion. While limited by their cross-sectional nature, with longitudinal replication, result may have implications for identifying cannabis use regimens that minimize frequency of use and thereby reduce risk for negative health outcomes.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"161 ","pages":"Article 108203"},"PeriodicalIF":3.7,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142650023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metacognitive beliefs and desire thinking as potential maintenance factors of compulsive sexual behavior","authors":"Carlotta Olivari ,&nbsp;Giovanni Mansueto ,&nbsp;Claudia Marino ,&nbsp;Giulio Candellari ,&nbsp;Jessica Cericola ,&nbsp;Jon Binnie ,&nbsp;Marcantonio M. Spada ,&nbsp;Gabriele Caselli","doi":"10.1016/j.addbeh.2024.108214","DOIUrl":"10.1016/j.addbeh.2024.108214","url":null,"abstract":"<div><div>Using the Elaborated Intrusion Theory of Desire and the Self-Regulatory Executive Function model of psychopathology as bases, this study explored whether metacognitive beliefs and desire thinking (DT) are associated with higher levels of Compulsive Sexual Behavior (CSB). A total of 1185 participants from the general population were included in the study (mean ± SD age = 25.32 years ± 5.58; age range = 18–19 years; females = 76.7 %). Metacognitive beliefs, DT, CSB, anxiety and depressive symptoms were assessed. Correlation analyses and path analyses were run. Results of the path analysis showed that positive metacognitive beliefs about DT were associated with DT-Imaginal Prefiguration (DT-IP), which in turn was positively associated with DT-Verbal Perseveration (DT-VP). The latter was strongly and positively associated with negative metacognitive beliefs about DT, which in turn was linked to CSB. Moreover, DT-VP was also found to be directly linked to the outcome variable and positive metacognitive beliefs about DT were also directly linked to DT-VP and negative metacognitive beliefs about DT. The total Coefficient of Determination (0.45) indicated a good fit to the observed data. Metacognitive beliefs and DT may be potential maintenance factors in CSB. Metacognitive beliefs and DT could also be considered as potential therapeutic targets in clinical interventions aimed at reducing the severity of CSB.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"161 ","pages":"Article 108214"},"PeriodicalIF":3.7,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142694005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The co-occurrence between symptoms of internet gaming disorder, depression, and anxiety in middle and late adolescence: A cross-lagged panel network analysis","authors":"Tingting Gao ,&nbsp;Yan Chen ,&nbsp;Qian Gai ,&nbsp;Carl D’Arcy ,&nbsp;Yingying Su","doi":"10.1016/j.addbeh.2024.108215","DOIUrl":"10.1016/j.addbeh.2024.108215","url":null,"abstract":"<div><div>Although there is a growing awareness of the co-occurrence of internet gaming disorder (IGD) with other mental health problems, the specific patterns of how these symptoms interact over time, especially across different age groups, remain unclear. The current study utilizes cross-lagged panel network modeling (CLPN) to investigate the dynamic, longitudinal relationships among symptoms of IGD, depression and anxiety among adolescents across time, and how these connections change with different developmental stages. A total of 3296 middle and late adolescents who have finished 3-time points research were included in the present study. Significant differences were found between middle and late adolescents in the structures and strengths of the contemporaneous and longitudinal networks. For middle adolescents, symptoms tended to predict subsequent symptoms within the same disorder. However, late adolescents showed a stronger trend of symptoms being interconnected across comorbid conditions. <em>Feelings of worthlessness</em> &amp; <em>hopelessness</em> were the most impactful symptoms for middle adolescents in the short term and they continued to significantly affect late adolescents in the long term. In addition, <em>restless</em> and <em>suicide or self-harm</em> were the most important bridge symptoms for middle and late adolescents, respectively. This study emphasizes the importance of developing targeted intervention strategies focusing on both central and bridging symptoms of the comorbid conditions of IGD, depression, and anxiety in adolescence. Recognizing distinct adolescents’ needs, interventions should be tailored to effectively address the unique challenges at different developmental stages.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"161 ","pages":"Article 108215"},"PeriodicalIF":3.7,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of rumination on problematic mobile phone use among female freshmen: A moderated mediation model","authors":"Yifan Yu ,&nbsp;Chengjie Zhang ,&nbsp;Jiaojiao Wan ,&nbsp;Yafei Zhang ,&nbsp;Lili Ji ,&nbsp;Chaoran Chen","doi":"10.1016/j.addbeh.2024.108213","DOIUrl":"10.1016/j.addbeh.2024.108213","url":null,"abstract":"<div><div>Based on the Interaction of Person-Affect-Cognition-Execution model and the risk-buffering model, the current study explored how and when rumination increases problematic mobile phone use (PMPU) among Chinese female freshmen. Specifically, we investigated the underlying mechanism of PMPU by testing a moderated mediation model in which solitude capacity moderated the mediating role of fear of missing out (FoMO) in the relationship between rumination and PMPU. A sample of 1,389 female freshmen in China, with a mean age of 19.68 years (SD = 2.63), was surveyed using the Rumination Response Scale, Fear of Missing Out Scale, Solitude Capacity Scale, and Mobile Phone Addiction Index. Mediation analysis indicated that rumination increases female freshmen’s PMPU by heightening FoMO. Moderated mediation analysis further demonstrated that high capacity for solitude mitigated the adverse effects of FoMO on PMPU among female freshmen, whereas low capacity for solitude exacerbates the negative impact of FoMO on PMPU in this group. This study highlights the mediating and moderating mechanisms linking rumination to PMPU. More importantly, it has significant implications for the prevention and intervention of PMPU among female freshmen.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"161 ","pages":"Article 108213"},"PeriodicalIF":3.7,"publicationDate":"2024-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of social-cognitive factors in the relationship between e-cigarette use and subsequent cigarette smoking among U.S. youth: A causal mediation analysis","authors":"Shu Xu ,&nbsp;Donna L. Coffman ,&nbsp;George Luta ,&nbsp;Andi Mai ,&nbsp;Nan Jiang ,&nbsp;Raymond S. Niaura","doi":"10.1016/j.addbeh.2024.108204","DOIUrl":"10.1016/j.addbeh.2024.108204","url":null,"abstract":"<div><h3>Objective</h3><div>E-cigarette use is associated with subsequent cigarette smoking among youth. The current study examined the mediating role of social-cognitive factors in this association.</div></div><div><h3>Methods</h3><div>Data from four waves of the Population Assessment of Tobacco and Health study (2013/4 – 2017/8) were analyzed. Among youth who had heard about e-cigarettes at Wave 1 but never used cigarettes before Wave 2, we conducted both causal and traditional mediation analyses to examine the mediated effect of social-cognitive factors (including relative harm perception of e-cigarettes versus cigarettes, harm perception of e-cigarette use, perceptions of addictiveness of e-cigarette use, and e-cigarette use among best friends) in the association between e-cigarette use and subsequent cigarette ever or current smoking, adjusting for covariates. We included sampling weights in all analyses; hence, results are generalizable to the U.S. youth (12 – 14 years) from the 2013–2014 cohort.</div></div><div><h3>Results</h3><div>Results from causal mediation analyses indicated that the total effect of e-cigarette use, compared to no use, increased the risk of cigarette ever smoking (20.9 %) and current smoking (4.6 %). A portion of this effect (4.2 % − 15.1 % for ever smoking; less than 10.6 % for current smoking) can be attributed to changes in social-cognitive factors induced by e-cigarette use. However, these mediated effects were small in magnitude relative to their standard errors and not statistically significant. Results from the traditional mediation analyses largely aligned with these findings, except for a few small sized pathways.</div></div><div><h3>Conclusions</h3><div>For the U.S. youth population, social-cognitive factors may only minimally or not at all mediate the association between e-cigarette use and subsequent cigarette smoking. Further investigation into the mediation role of social-cognitive factors is warranted. Tobacco control interventions that focus on cigarette smoking initiation among youth should target other mediating factors.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"161 ","pages":"Article 108204"},"PeriodicalIF":3.7,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"E-cigarette access and age verification among adolescents, young adults, and adults","authors":"Shivani Mathur Gaiha ,&nbsp;Lauren Kass Lempert ,&nbsp;Crystal Lin ,&nbsp;Bonnie Halpern-Felsher","doi":"10.1016/j.addbeh.2024.108193","DOIUrl":"10.1016/j.addbeh.2024.108193","url":null,"abstract":"<div><h3>Background</h3><div>Adolescents and young adults continue to access e-cigarettes despite regulatory efforts to prevent sales to those under 21. Prior research on sources of acquiring e-cigarettes excludes key online sources. This study aims to update evidence on where and how different age groups (adolescents, young adults, and adults) access e-cigarettes.</div></div><div><h3>Methods</h3><div>A cross-sectional, online survey of 13–40 year-olds who used e-cigarettes in the past 30 days was conducted from November-December 2021. Study outcomes: where past 30-day users obtained and bought e-cigarettes (retail stores; online, including e-cigarette company and multi-brand websites; social media; home delivery applications; and someone they know); and whether and how age was verified.</div></div><div><h3>Results</h3><div>In our sample, 55.0% reported obtaining e-cigarettes from retail stores, 44.9% online, and 24.0% from someone they know (n = 2,256), although most 13–17-year-olds obtained their e-cigarettes from someone they know. Double the proportion of 21–40-year-olds (7.0%) and higher than 18–20-year-olds (9.8%), 13.4% of 13–17-year-olds obtained e-cigarettes through social media. Social media, Snapchat, Instagram, and TikTok were common platforms to buy e-cigarettes among those under 21; common sources on social media included friends their age, store/company accounts, and influencers. Approximately 20.0% of those under 21 bought e-cigarettes from internet vendors (including multi-brand websites) and 10.4–15.5% used home delivery applications. Across participants, 14.2% reported that their age was not verified, and 17.8% reported that their age was rarely verified.</div></div><div><h3>Conclusions</h3><div>A sizeable proportion of adolescents and young adults under 21 years and adults above 21 acquired e-cigarettes from retail and online sources. Less than a quarter of those underage reported having their age verified all the time, warranting enforcement of existing age verification regulation and development of strategies to prevent underage access online.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"161 ","pages":"Article 108193"},"PeriodicalIF":3.7,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mobile phone ownership, social media use, and substance use at ages 11–13 in the ABCD study","authors":"Neal Doran ,&nbsp;Natasha E. Wade ,&nbsp;Kelly E. Courtney ,&nbsp;Ryan M. Sullivan ,&nbsp;Joanna Jacobus","doi":"10.1016/j.addbeh.2024.108211","DOIUrl":"10.1016/j.addbeh.2024.108211","url":null,"abstract":"<div><h3>Introduction</h3><div>There is ongoing concern about the impact of increasing use of social media and digital devices on unhealthy behaviors such as substance use in youth. Mobile phone and social media use have been associated with substance use in adolescent and young adult samples, but few studies have evaluated these relationships in younger samples.</div></div><div><h3>Methods</h3><div>This secondary analysis of data drawn from the ABCD Study examined associations between youth-reported mobile phone ownership and social media use at age 11–12 and use of alcohol, nicotine/tobacco, and cannabis over the next 18 months.</div></div><div><h3>Results</h3><div>Longitudinal logistic regression was used to test the hypothesis that phone ownership and social media use at age 11–12 would predict substance use over time. Phone ownership was associated with greater odds of alcohol and nicotine/tobacco use, and social media use was associated with greater odds of using nicotine/tobacco and cannabis.</div></div><div><h3>Conclusions</h3><div>These findings suggest that pre-teen youth who own mobile phones and those who use social media may be at greater risk for substance use. Further research is needed to specify mechanisms by which this association occurs and thus inform prevention and intervention efforts.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"161 ","pages":"Article 108211"},"PeriodicalIF":3.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exposure to Bupropion-SR vs. Placebo is associated with reductions in smoking among persons receiving methadone with no stated interest in smoking cessation","authors":"Orrin D. Ware ,&nbsp;Maxine L. Stitzer ,&nbsp;Annie Umbricht ,&nbsp;Kelly E. Dunn","doi":"10.1016/j.addbeh.2024.108202","DOIUrl":"10.1016/j.addbeh.2024.108202","url":null,"abstract":"<div><div>Smoking is prevalent among individuals receiving methadone treatment. Reducing smoking among this population is needed as smoking is a leading cause of morbidity and preventable death. Smoking cessation interventions for persons receiving medication for opioid use disorder have yielded small changes in abstinence. Bupropion-SR was developed as an anti-depressant medication and is a first-line medication for smoking cessation. There is limited research on the effectiveness of bupropion-SR on smoking cessation among individuals receiving medication for opioid use disorder. This study is a secondary analysis of N = 72 adults enrolled in methadone treatment who endorsed smoking cigarettes. Participants were randomized to receive bupropion-SR 150 mg twice-daily (n = 35) or placebo (n = 37) in the primary study that examined bupropion-SR on cocaine use outcomes over a 30-weeks. Mixed model analyses examined secondary changes in self-reported cigarettes smoked, a self-reported measure of nicotine dependence, and quantitative urinary cotinine values. The longitudinal analysis of self-reported daily cigarettes identified no main effects of group and week however a significant interaction between group and week revealed that persons receiving bupropion-SR group reported less smoking early in the intervention. Longitudinal evaluation of changes in urinary cotinine revealed a significant main effect of week but no main effect of group or group x week interaction. Data suggest that bupropion-SR significantly decreased the number of self-reported cigarettes smoked relative to placebo and reduced nicotine dependence severity by the end of the study. Follow-up studies are needed as these decreases were not identified throughout the full study period or at termination.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"161 ","pages":"Article 108202"},"PeriodicalIF":3.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142593204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}