T. Snooks , P.G. Tibbo , P. Romero-Sanchiz , S. DeGrace , S.H. Stewart
{"title":"Cannabis use regimens in trauma-exposed individuals: Associations with cannabis use quantity and frequency","authors":"T. Snooks , P.G. Tibbo , P. Romero-Sanchiz , S. DeGrace , S.H. Stewart","doi":"10.1016/j.addbeh.2024.108203","DOIUrl":"10.1016/j.addbeh.2024.108203","url":null,"abstract":"<div><div>People with trauma histories have an increased odds of cannabis use. Little is known about the frequency or consequences of different cannabis use regimens in cannabis users with trauma histories. Individuals with anxiety disorders tend to administer benzodiazepines in a <em>pro re nata</em> (PRN; i.e., as needed) as opposed to regularly scheduled (RS, e.g., twice daily [BID], three times daily [TID]) manner. Although physicians tend to prescribe benzodiazepines on a PRN regimen to minimize use, this regimen is paradoxically associated with greater use levels. Indeed, PRN administration regimens may increase use via negative reinforcement processes. We extended this older benzodiazepine literature to cannabis by examining regimen of cannabis use among 94 trauma-exposed cannabis users (mean age = 35.1 years; 52.1 % male; 23.4 % with cannabis prescription). Participants reported their initial and current cannabis use regimen (PRN vs. RS vs. both [‘PRN+’]) and their past month cannabis use frequency (use occasions in last month) and quantity (grams/use occasion). Consistent with patterns in benzodiazepine research, PRN (47.1 % of sample) and PRN+ (43.5 % of sample) were more common than RS regimens (9.4 % of sample). Also consistent with patterns seen with benzodiazepines, our sample moved toward PRN regimens from initial to current use: e.g., 100 % of initial RS users switched to a regimen that included PRN use. Consistent with predictions emerging from learning theory, PRN and PRN+ cannabis users reported significantly higher cannabis use frequencies compared to RS users (<em>p</em>’s < 0.01). Unexpectedly, there were no significant differences between cannabis use regimen groups for quantity of cannabis/occasion. While limited by their cross-sectional nature, with longitudinal replication, result may have implications for identifying cannabis use regimens that minimize frequency of use and thereby reduce risk for negative health outcomes.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"161 ","pages":"Article 108203"},"PeriodicalIF":3.7,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142650023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yifan Yu , Chengjie Zhang , Jiaojiao Wan , Yafei Zhang , Lili Ji , Chaoran Chen
{"title":"The effect of rumination on problematic mobile phone use among female freshmen: A moderated mediation model","authors":"Yifan Yu , Chengjie Zhang , Jiaojiao Wan , Yafei Zhang , Lili Ji , Chaoran Chen","doi":"10.1016/j.addbeh.2024.108213","DOIUrl":"10.1016/j.addbeh.2024.108213","url":null,"abstract":"<div><div>Based on the Interaction of Person-Affect-Cognition-Execution model and the risk-buffering model, the current study explored how and when rumination increases problematic mobile phone use (PMPU) among Chinese female freshmen. Specifically, we investigated the underlying mechanism of PMPU by testing a moderated mediation model in which solitude capacity moderated the mediating role of fear of missing out (FoMO) in the relationship between rumination and PMPU. A sample of 1,389 female freshmen in China, with a mean age of 19.68 years (SD = 2.63), was surveyed using the Rumination Response Scale, Fear of Missing Out Scale, Solitude Capacity Scale, and Mobile Phone Addiction Index. Mediation analysis indicated that rumination increases female freshmen’s PMPU by heightening FoMO. Moderated mediation analysis further demonstrated that high capacity for solitude mitigated the adverse effects of FoMO on PMPU among female freshmen, whereas low capacity for solitude exacerbates the negative impact of FoMO on PMPU in this group. This study highlights the mediating and moderating mechanisms linking rumination to PMPU. More importantly, it has significant implications for the prevention and intervention of PMPU among female freshmen.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"161 ","pages":"Article 108213"},"PeriodicalIF":3.7,"publicationDate":"2024-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shu Xu , Donna L. Coffman , George Luta , Andi Mai , Nan Jiang , Raymond S. Niaura
{"title":"Role of social-cognitive factors in the relationship between e-cigarette use and subsequent cigarette smoking among U.S. youth: A causal mediation analysis","authors":"Shu Xu , Donna L. Coffman , George Luta , Andi Mai , Nan Jiang , Raymond S. Niaura","doi":"10.1016/j.addbeh.2024.108204","DOIUrl":"10.1016/j.addbeh.2024.108204","url":null,"abstract":"<div><h3>Objective</h3><div>E-cigarette use is associated with subsequent cigarette smoking among youth. The current study examined the mediating role of social-cognitive factors in this association.</div></div><div><h3>Methods</h3><div>Data from four waves of the Population Assessment of Tobacco and Health study (2013/4 – 2017/8) were analyzed. Among youth who had heard about e-cigarettes at Wave 1 but never used cigarettes before Wave 2, we conducted both causal and traditional mediation analyses to examine the mediated effect of social-cognitive factors (including relative harm perception of e-cigarettes versus cigarettes, harm perception of e-cigarette use, perceptions of addictiveness of e-cigarette use, and e-cigarette use among best friends) in the association between e-cigarette use and subsequent cigarette ever or current smoking, adjusting for covariates. We included sampling weights in all analyses; hence, results are generalizable to the U.S. youth (12 – 14 years) from the 2013–2014 cohort.</div></div><div><h3>Results</h3><div>Results from causal mediation analyses indicated that the total effect of e-cigarette use, compared to no use, increased the risk of cigarette ever smoking (20.9 %) and current smoking (4.6 %). A portion of this effect (4.2 % − 15.1 % for ever smoking; less than 10.6 % for current smoking) can be attributed to changes in social-cognitive factors induced by e-cigarette use. However, these mediated effects were small in magnitude relative to their standard errors and not statistically significant. Results from the traditional mediation analyses largely aligned with these findings, except for a few small sized pathways.</div></div><div><h3>Conclusions</h3><div>For the U.S. youth population, social-cognitive factors may only minimally or not at all mediate the association between e-cigarette use and subsequent cigarette smoking. Further investigation into the mediation role of social-cognitive factors is warranted. Tobacco control interventions that focus on cigarette smoking initiation among youth should target other mediating factors.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"161 ","pages":"Article 108204"},"PeriodicalIF":3.7,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"E-cigarette access and age verification among adolescents, young adults, and adults","authors":"Shivani Mathur Gaiha , Lauren Kass Lempert , Crystal Lin , Bonnie Halpern-Felsher","doi":"10.1016/j.addbeh.2024.108193","DOIUrl":"10.1016/j.addbeh.2024.108193","url":null,"abstract":"<div><h3>Background</h3><div>Adolescents and young adults continue to access e-cigarettes despite regulatory efforts to prevent sales to those under 21. Prior research on sources of acquiring e-cigarettes excludes key online sources. This study aims to update evidence on where and how different age groups (adolescents, young adults, and adults) access e-cigarettes.</div></div><div><h3>Methods</h3><div>A cross-sectional, online survey of 13–40 year-olds who used e-cigarettes in the past 30 days was conducted from November-December 2021. Study outcomes: where past 30-day users obtained and bought e-cigarettes (retail stores; online, including e-cigarette company and multi-brand websites; social media; home delivery applications; and someone they know); and whether and how age was verified.</div></div><div><h3>Results</h3><div>In our sample, 55.0% reported obtaining e-cigarettes from retail stores, 44.9% online, and 24.0% from someone they know (n = 2,256), although most 13–17-year-olds obtained their e-cigarettes from someone they know. Double the proportion of 21–40-year-olds (7.0%) and higher than 18–20-year-olds (9.8%), 13.4% of 13–17-year-olds obtained e-cigarettes through social media. Social media, Snapchat, Instagram, and TikTok were common platforms to buy e-cigarettes among those under 21; common sources on social media included friends their age, store/company accounts, and influencers. Approximately 20.0% of those under 21 bought e-cigarettes from internet vendors (including multi-brand websites) and 10.4–15.5% used home delivery applications. Across participants, 14.2% reported that their age was not verified, and 17.8% reported that their age was rarely verified.</div></div><div><h3>Conclusions</h3><div>A sizeable proportion of adolescents and young adults under 21 years and adults above 21 acquired e-cigarettes from retail and online sources. Less than a quarter of those underage reported having their age verified all the time, warranting enforcement of existing age verification regulation and development of strategies to prevent underage access online.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"161 ","pages":"Article 108193"},"PeriodicalIF":3.7,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neal Doran , Natasha E. Wade , Kelly E. Courtney , Ryan M. Sullivan , Joanna Jacobus
{"title":"Mobile phone ownership, social media use, and substance use at ages 11–13 in the ABCD study","authors":"Neal Doran , Natasha E. Wade , Kelly E. Courtney , Ryan M. Sullivan , Joanna Jacobus","doi":"10.1016/j.addbeh.2024.108211","DOIUrl":"10.1016/j.addbeh.2024.108211","url":null,"abstract":"<div><h3>Introduction</h3><div>There is ongoing concern about the impact of increasing use of social media and digital devices on unhealthy behaviors such as substance use in youth. Mobile phone and social media use have been associated with substance use in adolescent and young adult samples, but few studies have evaluated these relationships in younger samples.</div></div><div><h3>Methods</h3><div>This secondary analysis of data drawn from the ABCD Study examined associations between youth-reported mobile phone ownership and social media use at age 11–12 and use of alcohol, nicotine/tobacco, and cannabis over the next 18 months.</div></div><div><h3>Results</h3><div>Longitudinal logistic regression was used to test the hypothesis that phone ownership and social media use at age 11–12 would predict substance use over time. Phone ownership was associated with greater odds of alcohol and nicotine/tobacco use, and social media use was associated with greater odds of using nicotine/tobacco and cannabis.</div></div><div><h3>Conclusions</h3><div>These findings suggest that pre-teen youth who own mobile phones and those who use social media may be at greater risk for substance use. Further research is needed to specify mechanisms by which this association occurs and thus inform prevention and intervention efforts.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"161 ","pages":"Article 108211"},"PeriodicalIF":3.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Deirdre Mongan , Seán R Millar , Margaret M Brennan , Anne Doyle , Brian Galvin , Noel McCarthy
{"title":"Associations and mediating factors between adverse childhood experiences and substance use behaviours in early adulthood: A population-based longitudinal study","authors":"Deirdre Mongan , Seán R Millar , Margaret M Brennan , Anne Doyle , Brian Galvin , Noel McCarthy","doi":"10.1016/j.addbeh.2024.108194","DOIUrl":"10.1016/j.addbeh.2024.108194","url":null,"abstract":"<div><h3>Background</h3><div>Research has demonstrated positive associations between adverse childhood experiences (ACEs) and substance use behaviours in young adults. However, many of these are based on cross-sectional data. The pathway between ACEs and substance misuse among emerging adults is also not fully understood and few studies have investigated potential mediating factors.</div></div><div><h3>Methods</h3><div>We analysed data from the Child Cohort of the Growing Up in Ireland study, a nationally representative longitudinal sample of children recruited at 9 years of age (n = 4,729). Logistic regression was used to examine individual and cumulative ACE exposure relationships with substance use at age 20 years. Mediation analyses were used to assess whether parental and peer relationships and school engagement mediate ACE history associations with substance use behaviours.</div></div><div><h3>Results</h3><div>ACE exposure relationships with current cannabis use, other illicit drug use and problematic drug use were observed. In particular, young adults who had experienced 2 ACEs or 3 + ACEs had an approximate two-fold (OR=1.80, 95 % CI: 1.29, 2.51) and approximate three-fold (OR=2.94, 95 % CI: 2.06, 4.19) increased odds of problematic drug use, respectively, when compared to participants who had experienced no ACEs during the study period. Mediation analyses suggested that parent and peer attachment and liking school partially mediate relationships between ACEs and substance use behaviours.</div></div><div><h3>Conclusions</h3><div>Children who have experienced ACEs are at higher risk of future substance use and problematic drug use. In supporting these children, identified mediators such as interpersonal relationships and school engagement may help guide selection of prevention interventions.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"161 ","pages":"Article 108194"},"PeriodicalIF":3.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mauro Pettorruso, Francesco Di Carlo, Giorgio Di Lorenzo, Giovanni Martinotti
{"title":"Hippocrates in addiction and the need for transdiagnostic phenotypes to address evidence-based interventions","authors":"Mauro Pettorruso, Francesco Di Carlo, Giorgio Di Lorenzo, Giovanni Martinotti","doi":"10.1016/j.addbeh.2024.108190","DOIUrl":"10.1016/j.addbeh.2024.108190","url":null,"abstract":"","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"160 ","pages":"Article 108190"},"PeriodicalIF":3.7,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142568908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Derrick S. Lee , Alayna P. Tackett , Christine Naya , Alyssa F. Harlow , Tyler B. Mason
{"title":"Trajectories of body mass index and combustible and electronic cigarette use across adolescence: Findings from the PATH study","authors":"Derrick S. Lee , Alayna P. Tackett , Christine Naya , Alyssa F. Harlow , Tyler B. Mason","doi":"10.1016/j.addbeh.2023.107901","DOIUrl":"10.1016/j.addbeh.2023.107901","url":null,"abstract":"<div><h3>Purpose</h3><p>Associations between empirically-generated body mass index (BMI) trajectories and risk of current use of combustible cigarettes and e-cigarettes across adolescence were examined using longitudinal data from the Population Assessment of Tobacco and Health (PATH) study.</p></div><div><h3>Methods</h3><p>The PATH study is an ongoing annual longitudinal population-based study of adolescents. We utilized Waves 1–4 conducted from 2013 to 2017. Adolescents completed self-reported surveys of their height, weight, and current tobacco use at Waves 1–4 and their tobacco weight control beliefs at Waves 1–2.</p></div><div><h3>Results</h3><p>Using latent growth mixture modeling, six trajectories of BMI were identified. The largest group (“normal weight increasing;” <em>n</em> = 4,858; 86.6 %), which was used as the comparator in subsequent analyses, consisted of adolescents ages 12–17 who were normal weight at Wave 1 with a significant increase in BMI across Waves 2––4. The “overweight early increasing,” “overweight late increasing,” and “obesity stable” classes had greater likelihood of current combustible cigarette use during the study compared to the “normal weight increasing class.” The “overweight early increasing,” “overweight late increasing,” and “overweight increasing then decreasing” classes showed elevated risk for e-cigarette use during the study. Compared to those in the “normal weight increasing” class, those in the “overweight increasing then decreasing” and “obesity stable” classes had greater weight control beliefs at Wave 1 and those in the “obesity stable” class had greater weight control beliefs at Wave 2.</p></div><div><h3>Conclusions</h3><p>Findings highlight the importance of weight trajectories and weight control beliefs by tobacco product use across adolescence and the need for mechanistic and intervention research.</p></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"149 ","pages":"Article 107901"},"PeriodicalIF":4.4,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71489783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marc L. Steinberg , Rachel L. Rosen , Ollie Ganz , Olivia A. Wackowski , Michelle Jeong , Cristine D. Delnevo
{"title":"Communicating the benefits of quitting smoking on mental health increases motivation to quit in people with anxiety and/or depression","authors":"Marc L. Steinberg , Rachel L. Rosen , Ollie Ganz , Olivia A. Wackowski , Michelle Jeong , Cristine D. Delnevo","doi":"10.1016/j.addbeh.2023.107903","DOIUrl":"10.1016/j.addbeh.2023.107903","url":null,"abstract":"<div><h3>Background</h3><p>Although smoking rates have declined over time, this decline has not been observed among those with mental health concerns. It is therefore important to develop effective messaging to support quitting in this population.</p></div><div><h3>Methods</h3><p>We conducted an online experiment with 419 adults who smoke cigarettes daily. Participants with, or without a lifetime history of anxiety and/or depression were randomized to view a message focused on the benefits of quitting smoking on mental or physical health. Participants then reported motivation to quit smoking, mental health concerns about quitting, and perceived effectiveness of the message.</p></div><div><h3>Results</h3><p>Participants with a lifetime history of anxiety and/or depression who saw the message focused on the benefits of quitting smoking on mental health reported greater motivation to quit than when they saw a message focused on the benefits to physical health. This was not replicated when examining current symptoms instead of lifetime history. Pre-existing beliefs that smoking improves one’s mood were greater in those experiencing current symptoms and in those with a lifetime history of anxiety and/or depression. There was no main or interaction (message type X mental health status) effect of message type received on mental health related concerns about quitting.</p></div><div><h3>Conclusions</h3><p>This study is one of the first to evaluate a smoking cessation message with content specifically targeted to those with mental health concerns about quitting smoking. Additional work is needed to determine how to best target those with mental health concerns with messages focused on the benefits of quitting on mental health.</p></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"149 ","pages":"Article 107903"},"PeriodicalIF":4.4,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71489778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jerrius Jubran , Ashley Petersen , Katherine Harrison , Sharon Allen
{"title":"Delay discounting demonstrates lower impulsivity linked to a higher likelihood of succeeding at smoking cessation","authors":"Jerrius Jubran , Ashley Petersen , Katherine Harrison , Sharon Allen","doi":"10.1016/j.addbeh.2023.107900","DOIUrl":"10.1016/j.addbeh.2023.107900","url":null,"abstract":"<div><p>Sixty-eight percent of smokers want to quit, but only one in 10 are successful at smoking cessation. Recently, impulsivity has been studied in relation to smoking cessation with measures like the delay discounting task (DDT). We aimed to build on the robust literature that has already revealed the association between impulsivity and smoking cessation, as well as look at the differences between sexes for which there is conflicting evidence. We hypothesized that lower impulsivity would be positively associated with cessation success. In the parent cessation trial, participants were randomized to 12 weeks of progesterone or placebo. Participants were asked to quit smoking, and their smoking status was monitored via expired carbon monoxide throughout the study. Participants completed a DDT at screening, week 4, and week 8 using the 27-item Monetary Choice Questionnaire, where participants decided between a small immediate reward or a larger delayed reward (LDR). The effective delay 50 (ED50), which is the delay at which the LDR loses half its value, was analyzed. To estimate the association between ED50 and cessation, a logistic mixed model with a participant random intercept was fit, controlling for study week, randomization, sex, and age. For the 181 participants, a doubling of the ED50 was associated with an 18% increase in the odds of tobacco cessation (95% confidence interval: 0.2–38% increase; p=0.05). In agreement with our hypothesis, lower impulsivity correlated to greater tobacco cessation success. Our study also showed no evidence of sex differences in the association between ED50 and smoking cessation.</p></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"149 ","pages":"Article 107900"},"PeriodicalIF":4.4,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71489779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}