Adriana Lori, Alpa V. Patel, J. Lee Westmaas, W. Ryan Diver
{"title":"A novel smoking cessation behavior based on quit attempts may identify new genes associated with long-term abstinence","authors":"Adriana Lori, Alpa V. Patel, J. Lee Westmaas, W. Ryan Diver","doi":"10.1016/j.addbeh.2024.108192","DOIUrl":"10.1016/j.addbeh.2024.108192","url":null,"abstract":"<div><h3>Background</h3><div>Smoking cessation at any age has been shown to improve quality of life, decrease illness, and reduce mortality. About half of smokers attempt to quit each year, but only ∼ 7 % maintain long-term abstinence unaided. Few genetic factors have been consistently associated with smoking cessation, possibly due to poor phenotype definition.</div></div><div><h3>Methods</h3><div>We performed a genome-wide association study (GWAS) with an alternative phenotype based on the difficulty of quitting smoking (DQS) in the Cancer Prevention Study-3 cohort. Difficult quitters were defined as having made at least ten quit attempts, whether successful or not, and easy quitters as having quit after only one attempt. Only individuals of European ancestry were selected for the study. Among 10,004 smokers (5,071 difficult quitters, 4,933 easy quitters), we assessed the genetic heritability of DQS and evaluated associations between DQS and each genome-wide variant using logistic regression while adjusting for confounders, including smoking intensity (cigarettes per day).</div></div><div><h3>Results</h3><div>The genetic heritability of the DQS phenotype was 13 %, comparable to, or higher than, the reported heritability of other smoking behaviors (e.g., smoking intensity, cessation). Although no variants were genome-wide significant, several genes were identified at a subthreshold level (p < 10<sup>-4</sup>). A variant in <em>MEGF9</em> (rs149760032)<em>,</em> a transmembrane protein largely expressed in the central nervous system, showed the strongest association with DQS (OR = 0.60, p = 1.3x10<sup>-7</sup>). Additional variants associated with DQS independently by smoking intensity were also detected in <em>GLRA3</em> (rs73006492, OR = 0.77, p = 5.6x10<sup>-7</sup>) and <em>FOCAD</em> (rs112251973, OR = 1.96, p = 1.8x10<sup>-6</sup>) and are plausibly related to smoking cessation through pathways in the brain and respiratory system.</div></div><div><h3>Conclusions</h3><div>The use of an alternative cessation phenotype based on difficulty quitting smoking facilitated the identification of new pathways that could lead to unique smoking treatments.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"161 ","pages":"Article 108192"},"PeriodicalIF":3.7,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142587259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mauro Pettorruso, Francesco Di Carlo, Giorgio Di Lorenzo, Giovanni Martinotti
{"title":"Hippocrates in addiction and the need for transdiagnostic phenotypes to address evidence-based interventions","authors":"Mauro Pettorruso, Francesco Di Carlo, Giorgio Di Lorenzo, Giovanni Martinotti","doi":"10.1016/j.addbeh.2024.108190","DOIUrl":"10.1016/j.addbeh.2024.108190","url":null,"abstract":"","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"160 ","pages":"Article 108190"},"PeriodicalIF":3.7,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142568908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The mediating role of intentional self-regulation in the constructive and pathological compensation processes of problematic social networking use","authors":"Qianqian Li , Tianlong Chen , Shujing Zhang , Chuanhua Gu , Zongkui Zhou","doi":"10.1016/j.addbeh.2024.108188","DOIUrl":"10.1016/j.addbeh.2024.108188","url":null,"abstract":"<div><div>Perceived social isolation is a key predictor of college students’ problematic social networking site use (PSNSU). According to the Fear-Driven/Compensation-Seeking Hypothesis, reducing the fear of social isolation and compensating for social deficits serve as negative reinforcement motivations for SNS use, which may potentially result in PSNSU. This study investigated the association between perceived social isolation and PSNSU through the mediating roles of intentional self-regulation and parasocial relationships from a compensatory perspective. Additionally, gender differences in the mediating model were examined. Findings from an online survey of 893 college students in China revealed a positive relationship between perceived social isolation and PSNSU. The serial mediation model showed that intentional self-regulation and parasocial relationships both had positive individual mediating effects, as well as a negative serial mediating effect. Moreover, these mediating effects were only significant among women. The findings suggest that in the association between perceived social isolation and PSNSU, the mediating role of intentional self-regulation forms a constructive compensatory process, while its serial mediating role through parasocial relationships forms a pathological compensatory process. Interventions for PSNSU should take the mediating role of intentional self-regulation in constructive compensation process and the gender difference into consideration.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"160 ","pages":"Article 108188"},"PeriodicalIF":3.7,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142482782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kaitlin R. McManus , Alexandra Venegas , Ziva D. Cooper , Lara A. Ray
{"title":"Alcohol and cannabis co-use: Probing subjective response in eliciting cross-substance craving","authors":"Kaitlin R. McManus , Alexandra Venegas , Ziva D. Cooper , Lara A. Ray","doi":"10.1016/j.addbeh.2024.108189","DOIUrl":"10.1016/j.addbeh.2024.108189","url":null,"abstract":"<div><div>The co-use of alcohol and cannabis is rising in prevalence, yet the mechanisms driving individuals to co-use are not well understood. Subjective response to alcohol or cannabis may predict the desire to use either substance. However, which specific facets of subjective response predict cross-substance craving remains unclear. The present study investigated whether acute administration of alcohol or cannabis facilitates cue-induced craving for the other substance, with an emphasis on the underlying subjective response mechanisms contributing to co-use. This is a secondary analysis of a behavioral pharmacology study that combined alcohol/cannabis administration with a cross-substance cue-reactivity paradigm in individuals who were heavy alcohol and heavy cannabis co-users. Over two sessions, twenty-nine individuals (17M/12F) self-administered alcohol or cannabis (in a crossover design), and then completed a cue-reactivity exercise with the other substance. Analyses tested how changes in subjective response variables following substance administration predicted cross-substance cue-induced craving. Following alcohol administration, greater subjective ratings of positive mood predicted significantly greater cue-induced cannabis craving (β = 1.14, SE = 0.41, t = 2.80, <em>p</em> = 0.010). Following cannabis administration, lower subjective effects ratings of positive mood/arousal predicted significantly greater cue-induced alcohol craving (β = −1.08, SE = 0.38, t = −2.85, p = 0.009; β = −2.38, SE = 1.13, t = −2.10, p = 0.047). This study identified subject response mechanisms contributing to cross-substance cue induced craving. These mechanisms include increases in positive mood following alcohol use and decreases in positive mood and arousal, akin to increases in relaxation, following cannabis use.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"160 ","pages":"Article 108189"},"PeriodicalIF":3.7,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142445056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael J. Zvolensky , Tanya Smit , Ileana Dragoi , Rishitaa Tamminana , Jafar Bakhshaie , Joseph W. Ditre , Brooke Y. Redmond , Jeffrey Lackner
{"title":"Irritable Bowel Syndrome (IBS) and Smoking: An Evaluation of IBS symptom severity and anxiety sensitivity among adults in the United States","authors":"Michael J. Zvolensky , Tanya Smit , Ileana Dragoi , Rishitaa Tamminana , Jafar Bakhshaie , Joseph W. Ditre , Brooke Y. Redmond , Jeffrey Lackner","doi":"10.1016/j.addbeh.2024.108187","DOIUrl":"10.1016/j.addbeh.2024.108187","url":null,"abstract":"<div><h3>Introduction</h3><div>Irritable bowel syndrome (IBS) is a prevalent disorder of gut-brain function associated with psychological distress as well as work and quality of life impairment. Smoking has been linked to gastrointestinal dysfunction, however, research focused on the prevalence of IBS and smoking is limited. Previous research has shown that anxiety sensitivity is linked to increased risk of aversive bodily experiences and subsequent coping-oriented regulation efforts. Higher anxiety sensitivity has also been associated with processes linked to tobacco cigarette smoking lapse and relapse. There is a need to clarify the explanatory roles of anxiety sensitivity in the context of more severe IBS symptoms among persons with IBS who are current smokers.</div></div><div><h3>Method</h3><div>The present investigation evaluated the main and interactive effects of IBS symptom severity and anxiety sensitivity in relation to processes related to the maintenance and relapse of tobacco smoking among adults with IBS. The sample consisted of 263 (52.1 % female; <em>M<sub>age</sub></em> = 44.13 years, <em>SD</em> = 12.71) adults who met criteria for IBS and smoke at least 5 cigarettes per day.</div></div><div><h3>Results</h3><div>Hierarchical regression results indicated that both anxiety sensitivity and IBS symptom severity independently predicted greater perceived barriers to smoking cessation, severity of problems experienced during quitting, and negative reinforcement smoking expectancies. A statistically significant interaction further indicated that IBS symptom severity was more strongly associated with negative reinforcement smoking expectancies among participants with higher, relative to lower, anxiety sensitivity.</div></div><div><h3>Conclusions</h3><div>This study is the first to show that both IBS symptom severity and anxiety sensitivity are related to greater perceived barriers to smoking cessation, previous difficulty quitting, and negative reinforcement expectancies among adults with IBS. There is a continued need to further scientific understanding of interrelations between anxiety sensitivity, IBS symptom severity, and smoking cessation-related beliefs and processes to identify novel approaches that can best support quitting among this understudied population.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"160 ","pages":"Article 108187"},"PeriodicalIF":3.7,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142378676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kyzwana N. Caves , Prachi P. Chavan , Paul T. Harrell
{"title":"Effects of racial teasing on adolescent marijuana use and nicotine vaping: An analysis of the Virginia Youth Risk Behavior Surveillance System","authors":"Kyzwana N. Caves , Prachi P. Chavan , Paul T. Harrell","doi":"10.1016/j.addbeh.2024.108186","DOIUrl":"10.1016/j.addbeh.2024.108186","url":null,"abstract":"<div><h3>Background</h3><div>Despite adverse effects of tobacco and marijuana use on the adolescent brain, its use among youth remains high. Previous research shows associations between bullying and risks of substance use; less is known about racial teasing. This study examines associations of racial teasing, marijuana and/or electronic vapor products (EVP) use among adolescents, using 2021 Virginia Youth Risk Behavior Surveillance System (VYRBSS).</div></div><div><h3>Methods</h3><div>VYRBSS is a self-reported survey which collects information on experiences with racial teasing and substance use. This analysis included 3,083 high school students ≥ 12 years old. Descriptive analysis and logistic regression models were performed for categorical variables. Multivariable models were adjusted for confounders.</div></div><div><h3>Results</h3><div>Racial teasing was associated with marijuana (AOR 1.89; CI 1.43–2.48) and EVP use (AOR 2.52; CI 1.91–3.31). Compared to Whites; Asians, Blacks, and Latinos were more likely to report racial teasing. Older heterosexual females reported higher use of marijuana and EVP. Blacks reported greater use of marijuana, whereas Whites were more likely to use EVP. EVP use was higher in females (AOR 1.73, CI 1.34–2.23), bisexual youth (AOR 1.68, CI 1.23, 2.30) and poor mental health (AOR 1.49, CI 1.16, 1.92). Marijuana use was associated with bisexuality (AOR 1.75, CI 1.28–2.39) and poor mental health (AOR 1.62, CI 1.27–2.07) as well.</div></div><div><h3>Conclusions</h3><div>Every effort should be made by public health professionals in Virginia to prevent racial teasing among adolescents because it increases the odds of substance use, particularly in older females, youth who identify as bisexual, and those reporting poor mental health.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"160 ","pages":"Article 108186"},"PeriodicalIF":3.7,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yvonne M. Terry-McElrath, Yuk C. Pang, Megan E. Patrick
{"title":"Historical change in associations between perceived risk, disapproval, and use of cannabis among young adults ages 19–30, 2011–2022","authors":"Yvonne M. Terry-McElrath, Yuk C. Pang, Megan E. Patrick","doi":"10.1016/j.addbeh.2024.108185","DOIUrl":"10.1016/j.addbeh.2024.108185","url":null,"abstract":"<div><h3>Background</h3><div>The current study used U.S. young adult data to examine overall and age group-specific historical trends in (a) mean perceived risk and disapproval of cannabis use, and (b) risk/use and disapproval/use associations.</div></div><div><h3>Methods</h3><div>Data were collected from 2011 to 2022 from 16,492 respondents aged 19–30 in the national Monitoring the Future panel study. Trends in mean risk and disapproval overall and by age group (19–22, 23–26, 27–30) were modeled. Models regressing any past 30-day cannabis use on risk and disapproval controlled for sex, race/ethnicity, college education, population density, state cannabis policy, region, and year. Age group differences and historical trends in regression estimates from year-specific models were examined.</div></div><div><h3>Results</h3><div>From 2011 to 2022, overall mean perceived risk decreased from 3.08 (just over moderate) to 2.50 (between slight and moderate); mean disapproval decreased from 2.21 (between disapprove and strongly disapprove) to 1.66 (between don’t disapprove and disapprove). Higher risk and disapproval were independently associated with lower odds of past 30-day cannabis use overall (AORs 0.86 and 0.76, respectively); controlling for sociodemographics and state policy had virtually no impact on association strength. There were no significant age-related association differences. The risk/use association weakened from AOR 0.84 in 2011 to AOR 0.91 in 2022; the disapproval/use association remained stable (AORs 0.753 and 0.749).</div></div><div><h3>Conclusions</h3><div>Young adults now perceive cannabis as less risky and are less disapproving of using than they were a decade ago. Perceived risk has weakened as a cannabis use risk factor over time; disapproval has remained a stable risk factor.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"160 ","pages":"Article 108185"},"PeriodicalIF":3.7,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xinyi Wei , Huiling Zhou , Qiaoyi Zheng , Lei Ren , Niya Chen , Pengcheng Wang , Chang Liu
{"title":"Longitudinal Interactions between Problematic Internet Gaming and Symptoms of Depression Among University Students: Differentiating Anhedonia and Depressed Mood","authors":"Xinyi Wei , Huiling Zhou , Qiaoyi Zheng , Lei Ren , Niya Chen , Pengcheng Wang , Chang Liu","doi":"10.1016/j.addbeh.2024.108184","DOIUrl":"10.1016/j.addbeh.2024.108184","url":null,"abstract":"<div><div>Background/Objective: This study examines the interplay between problematic internet gaming (PIG) and depressive symptoms among university students, specifically anhedonia and depressed mood. Prior studies lacked distinction between these symptoms and had limited follow-ups. Method: The three-wave longitudinal study analyzed data from 1,720 university students (with an average age of 20 years and 49 % being female) using a random intercept cross-lagged panel model, which distinguished between-person and within-person effects. Results: At the between-person level, PIG was positively associated with two depressive symptoms. At the within-person level, PIG positively predicted future anhedonia. Besides, depressed mood positively predicted future PIG. Conclusions: Our results have identified PIG as a risk factor for anhedonia and depressed mood as a risk factor for PIG among university students.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"160 ","pages":"Article 108184"},"PeriodicalIF":3.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142407332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diana M. Doumas , Susan Esp , Rob Turrisi , Laura Bond , Shannon D. Glenn
{"title":"A randomized controlled trial testing the efficacy of the eCHECKUP TO GO on drinking games participation and behavior among high school seniors","authors":"Diana M. Doumas , Susan Esp , Rob Turrisi , Laura Bond , Shannon D. Glenn","doi":"10.1016/j.addbeh.2024.108183","DOIUrl":"10.1016/j.addbeh.2024.108183","url":null,"abstract":"<div><h3>Background</h3><div>Among high school students, seniors report the highest levels of hazardous drinking behavior, including playing drinking games. Technology-based interventions are a promising approach for reducing hazardous drinking behavior among this age group. <em>Objectives:</em> This randomized controlled trial investigated the efficacy of the eCHECKUP TO GO, an online personalized feedback intervention, on reducing the frequency of playing drinking games, the number of drinks consumed while playing drinking games, and the number of drinks consumed on occasions when drinking games were played among high school seniors (<span><span>ClinicalTrials.gov</span><svg><path></path></svg></span> Identifier NCT03613818). <em>Method:</em> Participants were recruited from two high schools. Class periods were randomized to the intervention condition or an assessment-only control condition. Participants completed online surveys at baseline, 30-day, and 6-month assessments. The subsample in this study (<em>N</em> = 109) consisted of high-risk drinkers (i.e., students reporting binge drinking in the past two weeks at baseline). <em>Results:</em> We did not find any significant differences in frequency of playing drinking games between the intervention and control conditions. For number of drinks consumed, students in the intervention condition reported a significant reduction in the number of drinks consumed while playing drinking games (<em>p</em> < 0.01) and total number of drinks consumed on drinking game occasions (<em>p</em> < 0.04) at the 30-day follow-up relative to students in the control condition. Reductions within the intervention group were sustained at the 6-month follow-up. <em>Conclusions:</em> Results support the efficacy of the eCHECKUP TO GO for decreasing hazardous alcohol use among high school seniors.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"160 ","pages":"Article 108183"},"PeriodicalIF":3.7,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Judith J. Prochaska , Erin A. Vogel , Marily Oppezzo , Jordan Skan , Mariah Knox , Amy Chieng , Maria C. Crouch , Rachael C. Aikens , Matthew Schnellbaecher , Neal L. Benowitz
{"title":"A randomized controlled trial evaluation of a smoking cessation and physical activity intervention delivered via telemedicine in the Norton Sound region of Alaska","authors":"Judith J. Prochaska , Erin A. Vogel , Marily Oppezzo , Jordan Skan , Mariah Knox , Amy Chieng , Maria C. Crouch , Rachael C. Aikens , Matthew Schnellbaecher , Neal L. Benowitz","doi":"10.1016/j.addbeh.2024.108179","DOIUrl":"10.1016/j.addbeh.2024.108179","url":null,"abstract":"<div><h3>Objectives</h3><div>Tobacco use disproportionately affects Alaska Native people. Physical activity may aid quitting smoking and provides health benefits. We tested telemedicine-delivered heart health interventions in Alaska’s Norton Sound region.</div></div><div><h3>Methods</h3><div>Alaska Native adults (N = 299, 51.5 % male, 60.5 % Inupiaq) with hypertension and/or hypercholesterolemia who smoked daily were randomized to intervention on smoking and physical activity (group 1) or traditional diet and medication adherence (group 2). Intention to change was not required for participation. Stage-tailored mailed workbooks and personalized reports were supported by telehealth counseling at baseline, 3, 6, and 12 months. Study outcomes were assessed at baseline, 3-, 6-, 12-, and 18-months (i.e., 6-months after the final counseling session). Smoking outcomes were self-reported 7-day point prevalence abstinence (7d-PPA),<span><span><sup>1</sup></span></span> bioconfirmed with urine anabasine; 24-hour quit attempts; and 50 % reduction in smoking. Self-reported physical activity outcomes were metabolic equivalent of task (MET) minutes and meeting moderate-to-vigorous physical activity (MVPA) guidelines.</div></div><div><h3>Results</h3><div>At baseline, participants averaged 12.4 (SD = 10.0) cigarettes/day, with 19.4 % prepared to quit smoking, and 81.6 % meeting MVPA guidelines. During the study, most (70.2 % group 1; 63.5 % group 2) reported a 24-hr quit attempt (p = 0.219), and Group 1 (53.6 %) was more likely than Group 2 (28.4 %) to use nicotine replacement therapy (NRT), OR = 2.92, p < 0.001. At 18-months, 40.5 % (group 1) and 32.5 % (group 2) had reduced their smoking by half or more (p = 0.343), and 10.8 % vs. 7.9 % (group 1 vs. 2) reported 7d-PPA with 4 % vs. 6 % (group 1 vs. 2) bioconfirmed. Time and baseline stage of change predicted 7d-PPA (p’s≤.015), with no group effect (p = 0.325). Activity levels did not significantly differ by group or time.</div></div><div><h3>Conclusions</h3><div>Telemedicine counseling supported NRT use but did not significantly affect behavioral outcomes.</div></div>","PeriodicalId":7155,"journal":{"name":"Addictive behaviors","volume":"160 ","pages":"Article 108179"},"PeriodicalIF":3.7,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142334132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}