Jiayue Zou , Yawei Qi , Shaoyu Tu , Yifei Zhang , Haichao Zhao , Jiali Liu , Ofir Turel , Hanlin Cheng , Qinghua He
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引用次数: 0
Abstract
Repeated nicotine exposure can lead to cognitive changes, including working memory. However, we have a limited understanding of such changes. To address this gap, 48 smokers participated in smoking-specific N-back tasks involving smoking and neutral cues under different working memory loads (1-back and 2-back), while EEG data were recorded. By employing drift–diffusion model and EEG analysis, we examined how cue types and working memory loads modulate behavioral performance and identified the underlying cognitive processes and neural correlates. The results showed decreased accuracy across working memory loads and slower reaction times specifically in the low working memory load condition when exposed to smoking cues. Drift-diffusion model analysis suggested that these effects may stem from reduced drift rate and a lower decision threshold. These behavioral differences between cue types were mirrored in the neural activity, with smoking cues eliciting smaller P300 amplitudes, decreased alpha and beta power under both working memory loads, and increased positive slow wave predominantly at low working memory load. Furthermore, negative correlations were observed between nicotine craving and behavior performance (i.e., accuracy), drift–diffusion model parameters (i.e., drift rate and decision threshold) and EEG data (i.e., alpha and beta power). These findings enhance our understanding of how smoking cues affect cognitive processing and the neural mechanisms of working memory in smokers.
期刊介绍:
Addictive Behaviors is an international peer-reviewed journal publishing high quality human research on addictive behaviors and disorders since 1975. The journal accepts submissions of full-length papers and short communications on substance-related addictions such as the abuse of alcohol, drugs and nicotine, and behavioral addictions involving gambling and technology. We primarily publish behavioral and psychosocial research but our articles span the fields of psychology, sociology, psychiatry, epidemiology, social policy, medicine, pharmacology and neuroscience. While theoretical orientations are diverse, the emphasis of the journal is primarily empirical. That is, sound experimental design combined with valid, reliable assessment and evaluation procedures are a requisite for acceptance. However, innovative and empirically oriented case studies that might encourage new lines of inquiry are accepted as well. Studies that clearly contribute to current knowledge of etiology, prevention, social policy or treatment are given priority. Scholarly commentaries on topical issues, systematic reviews, and mini reviews are encouraged. We especially welcome multimedia papers that incorporate video or audio components to better display methodology or findings.
Studies can also be submitted to Addictive Behaviors? companion title, the open access journal Addictive Behaviors Reports, which has a particular interest in ''non-traditional'', innovative and empirically-oriented research such as negative/null data papers, replication studies, case reports on novel treatments, and cross-cultural research.