Assessment of nicotine and cannabis co-use among adolescents and the association with nicotine and cannabis dependence symptoms

IF 3.6 2区医学 Q1 PSYCHOLOGY, CLINICAL

Addictive behaviors Pub Date : 2025-08-30 DOI:10.1016/j.addbeh.2025.108471

Nikki S. Jafarzadeh , Alyssa F. Harlow , Claire A. Walsh , Reid C. Whaley , Dae-Hee Han , Adam M. Leventhal , Jessica L. Barrington-Trimis

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引用次数: 0

Abstract

Significance

Adolescent nicotine and cannabis co-use is common, but prior studies use imprecise measurement of co-use which may not capture the most problematic behaviors such as same-day use.

Methods

This cross-sectional study examined patterns of nicotine and cannabis co-use among Southern California high school students in Fall 2022 (N = 3823). Participants were classified into five mutually exclusive past-month nicotine and cannabis use groups: 1) same-day co-use: use of both substances on the same day at least once; 2) past-month co-use: use of both without same-day use; 3) exclusive nicotine use; 4) exclusive cannabis use; 5) no use of either. Adjusted logistic regression models evaluated the association of co-use with any nicotine and/or cannabis dependence symptoms.

Results

Overall, 3.3% reported same-day co-use, 1.5% past-month co-use, 1.6% exclusive nicotine use, 3.1% exclusive cannabis use, and 90.5% no nicotine/cannabis use. Odds of cannabis dependence symptoms (aOR = 4.28, 95%CI[1.98–9.28]) were higher among the same-day vs. past-month co-use group, as were odds of nicotine dependence (aOR = 1.81, 95%CI[0.87–3.77]), though the result was not statistically significant. Compared to past-month co-use, exclusive cannabis use was associated with similar odds of cannabis dependence symptoms (aOR = 0.99, 95%CI[0.47–2.09]), while exclusive nicotine use was associated with non-significant lower odds of nicotine dependence symptoms (aOR = 0.42, 95%CI[0.17–1.04]).

Conclusion

Adolescents reporting same-day co-use had significantly greater cannabis dependence symptoms than those reporting past-month but not same-day use of both substances. Using a same-day definition of co-use might capture more problematic co-use behaviors.

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评估青少年中尼古丁和大麻的共同使用及其与尼古丁和大麻依赖症状的关系

青少年同时使用尼古丁和大麻是很常见的，但之前的研究使用了不精确的测量方法，这可能无法捕捉到最严重的问题行为，比如当天使用。方法本横断面研究调查了2022年秋季南加州高中生尼古丁和大麻的共同使用模式（N = 3823）。参与者在过去一个月内被分为五个相互排斥的尼古丁和大麻使用组：1)同日共同使用：在同一天使用这两种物质至少一次；2)近一个月共用：两者同时使用，不同日使用；3)独家使用尼古丁；4)独家使用大麻；5)两者都没有用。调整后的逻辑回归模型评估了共同使用与任何尼古丁和/或大麻依赖症状的关系。结果总体而言，3.3%的人报告当天共同使用，1.5%的人报告过去一个月共同使用，1.6%的人报告完全使用尼古丁，3.1%的人报告完全使用大麻，90.5%的人报告不使用尼古丁/大麻。同一天与过去一个月共同使用大麻的组出现大麻依赖症状的几率（aOR = 4.28, 95%CI[1.98-9.28]）更高，尼古丁依赖的几率（aOR = 1.81, 95%CI[0.87-3.77]）也更高，但结果无统计学意义。与过去一个月的共同使用相比，单独使用大麻与大麻依赖症状的几率相似（aOR = 0.99, 95%CI[0.47-2.09]），而单独使用尼古丁与尼古丁依赖症状的几率无显著降低相关（aOR = 0.42, 95%CI[0.17-1.04]）。结论报告同一天同时使用大麻的青少年比报告过去一个月同时使用两种物质的青少年有更大的大麻依赖症状。使用同日共同使用的定义可能会捕获更多有问题的共同使用行为。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Addictive behaviors 医学-药物滥用

CiteScore

8.40

自引率

4.50%

发文量

283

审稿时长

46 days

期刊介绍： Addictive Behaviors is an international peer-reviewed journal publishing high quality human research on addictive behaviors and disorders since 1975. The journal accepts submissions of full-length papers and short communications on substance-related addictions such as the abuse of alcohol, drugs and nicotine, and behavioral addictions involving gambling and technology. We primarily publish behavioral and psychosocial research but our articles span the fields of psychology, sociology, psychiatry, epidemiology, social policy, medicine, pharmacology and neuroscience. While theoretical orientations are diverse, the emphasis of the journal is primarily empirical. That is, sound experimental design combined with valid, reliable assessment and evaluation procedures are a requisite for acceptance. However, innovative and empirically oriented case studies that might encourage new lines of inquiry are accepted as well. Studies that clearly contribute to current knowledge of etiology, prevention, social policy or treatment are given priority. Scholarly commentaries on topical issues, systematic reviews, and mini reviews are encouraged. We especially welcome multimedia papers that incorporate video or audio components to better display methodology or findings. Studies can also be submitted to Addictive Behaviors? companion title, the open access journal Addictive Behaviors Reports, which has a particular interest in ''non-traditional'', innovative and empirically-oriented research such as negative/null data papers, replication studies, case reports on novel treatments, and cross-cultural research.