{"title":"Syntheses, Crystal Structures and Antimicrobial Activity of NiII, ZnII and MnIII Complexes Derived from N,N'-Bis(4-bromosalicylidene)propane-1,2-diamine.","authors":"Yu-Mei Hao","doi":"10.17344/acsi.2024.9122","DOIUrl":"https://doi.org/10.17344/acsi.2024.9122","url":null,"abstract":"<p><p>Four new nickel(II), zinc(II) and manganese(III) complexes, [NiL] (1), [Zn3L2(OAc)2] (2), [ZnL(CH3OH)] (3) and [MnClL(DMF)] (4), derived from the bis-Schiff base N,N'-bis(4-bromosalicylidene)propane-1,2-diamine (H2L) have been prepared and characterized by spectroscopy methods, as well as single crystal X-ray determination. The Ni atom in the mononuclear nickel complex 1 is in square planar coordination. The outer and inner Zn atoms in the trinuclear zinc complex 2 are in square planar and octahedral coordination, respectively. The Zn atom in the mononuclear zinc complex 3 is in square pyramidal coordination. The Mn atom in the mononuclear manganese complex 4 is in octahedral coordination. Antibacterial activity of the complexes has been assayed on the bacteria Staphylococcus aureus and Escherichia coli, and the yeast Candida parapsilosis.</p>","PeriodicalId":7122,"journal":{"name":"Acta Chimica Slovenica","volume":"72 1","pages":"119-126"},"PeriodicalIF":1.2,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143661734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Effect of Al2(SO4)3 on Compressive Strength in SLU Based on Ternary Binder System.","authors":"Nevin Karamahmut Mermer, Fatos Hatipoglu, Dilber Uludag, Ece Unlu Pinar","doi":"10.17344/acsi.2023.8115","DOIUrl":"https://doi.org/10.17344/acsi.2023.8115","url":null,"abstract":"<p><p>The early flexural and compressive strengths of fast setting SLU formulations based on a ternary system can be severely affected by the selection of accelerator, its quantity and chemistry. Besides design complexity, it is predicted that the current lithium resources will not be sufficient to meet the increasing demands from other markets and lithium prices are expected to increase. It is necessary to search for a new raw material that gives the same performance to prevent the possibility of a supply shortage in the construction sector. In this study, ternary system accelerated with aluminum sulphate was comprehensively investigated in comparison with commonly used accelerators. Aim to achieve is to provide early strength by using aluminum sulphate in the OPC-rich SLU formulation based on the ternary systems instead of traditional accelerators while obtaining cost saving solutions. For this purpose, fresh mortar properties and strength test were carried out according to EN 13813 and results were verified by monitoring hydration reactions over time by XRD and FTIR.</p>","PeriodicalId":7122,"journal":{"name":"Acta Chimica Slovenica","volume":"72 1","pages":"15-23"},"PeriodicalIF":1.2,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143661840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Using Eye-Movements to Explain Processing Triple Level of Chemical Information: Systematic Review.","authors":"Miha Slapničar, Luka Ribič, Iztok Devetak","doi":"10.17344/acsi.2024.9049","DOIUrl":"10.17344/acsi.2024.9049","url":null,"abstract":"<p><p>The focus of this systematic literature review was to examine eye-tracking studies in the chemistry classroom and to evaluate the usefulness of eye-tracking in studying students' learning of complex chemical concepts. The reviewed studies primarily used small samples of students, with undergraduate students being the most studied population, and measured variables such as eye movements, fixation time, pupil dilation, and others. The results show that higher performing students have shorter fixation time and learn better with models, with prior knowledge being an important factor. However, both students rely mainly on the symbolic level of presentations with better performing students being more successful at giving explanations. Problems with the complexity of data analysis were reported in the studies.</p>","PeriodicalId":7122,"journal":{"name":"Acta Chimica Slovenica","volume":"72 1","pages":"1-14"},"PeriodicalIF":1.2,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143661872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdulrahaman Mahmoud Dogara, Sawsan Sadiq Al-Rawi, Ateeq Ahmed Al-Zahrani, Abubakar Abdullahi Lema, Aisha Abdullahi Mahmud, Hasan Nudin Nur Fatihah, Iliyasu Uwaisu, Hussain Daifallah Almalki
{"title":"Biological activities, chemical composition and molecular docking of Urelytrum giganteum Pilg.","authors":"Abdulrahaman Mahmoud Dogara, Sawsan Sadiq Al-Rawi, Ateeq Ahmed Al-Zahrani, Abubakar Abdullahi Lema, Aisha Abdullahi Mahmud, Hasan Nudin Nur Fatihah, Iliyasu Uwaisu, Hussain Daifallah Almalki","doi":"10.17344/acsi.2024.9077","DOIUrl":"10.17344/acsi.2024.9077","url":null,"abstract":"<p><p>This study analyzed solvent extractions of Urelytrum giganteum Pilg, a perennial wild tufted grass in dry tropical African countries, to determine its antioxidant potential, chemical composition, proximate analysis, antimicrobial efficacy, and molecular docking. The ethanolic extract showed the highest antioxidant activity across various assays and showed the most substantial antibacterial activity against all tested bacterial strains. The phytochemicals identified included alkaloids, flavonoids, saponins, phenolic substances, tannins, carbohydrates, terpenes, and C-glycosides. The majority of the phytochemicals demonstrated notable inhibitory activity, with Stigmasterol showing the highest inhibition score.</p>","PeriodicalId":7122,"journal":{"name":"Acta Chimica Slovenica","volume":"72 1","pages":"107-118"},"PeriodicalIF":1.2,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pham M Tuan, Danh C Vu, Sy Vo Van, Ngo Thi Thuy, Vo Mong Tham, Nguyen Ngan
{"title":"Phytochemical composition, antioxidant and enzyme inhibitory effects of Stahlianthus thorelii Gagnep. rhizomes.","authors":"Pham M Tuan, Danh C Vu, Sy Vo Van, Ngo Thi Thuy, Vo Mong Tham, Nguyen Ngan","doi":"10.17344/acsi.2024.9043","DOIUrl":"10.17344/acsi.2024.9043","url":null,"abstract":"<p><p>Stahlianthus thorelii Gagnep. is used in traditional medicine to treat various diseases. In this study, ethyl acetate (EtOAc) extract of S. thorelii rhizomes was analyzed for its phychemicals, antioxidant activity and inhibition against enzymes (acetylcholinesterase, α-amylase, α-glucosidase, and tyrosinase). The EtOAc extract showed the presence of ferulic acid, catechin, epicatechin, epigallocatechin gallate, quercetin, and kaempferol, with average levels ranging from 169.29 to 2449.60 μg/g. Analysis of the volatile components of the extract revealed that β-patchoulene (23.1%), (E)-nerolidyl isobutyrate (11.9%), and aristolene (10.8%) were the major compounds. The antioxidant potential of the extract measured by DPPH (IC50 = 86.94 ± 2.87 μg/mL) and ABTS (IC50 = 743.60 ± 56.52 μg/mL) assays showed promising results. The inhibitory effects against acetylcholinesterase and α-amylase demonstrated potential with IC50 values of 246.43 ± 11.39 and 789.84 ± 8.27 µg/mL, respectively. The findings above suggest that the EtOAc extract of S. thorelii could contribute to supporting the treatment of certain diseases such as diabetes and Alzheimer's.</p>","PeriodicalId":7122,"journal":{"name":"Acta Chimica Slovenica","volume":"72 1","pages":"63-70"},"PeriodicalIF":1.2,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biomarkers of neuroinflammation in abdominal cancer surgery with optimised anaesthesia.","authors":"Matej Jenko, Aleš Jerin, Alenka Spindler Vesel","doi":"10.17344/acsi.2024.8901","DOIUrl":"10.17344/acsi.2024.8901","url":null,"abstract":"<p><p>Neurocognitive decline during the perioperative period represents a risk of significant complications, including dementia and even death. Our prospective study included high-risk surgical patients who underwent large intestinal resections. Balanced anaesthesia was used to maximize cerebral protection. The release of NSE, protein S-100, matrix metalloproteinase-9 (MMP-9) and other biomarkers of cerebral injury and inflammation were measured during and after surgery to obtain the perioperative concentration profile and to identify possible clinically useful markers. Profiles of proteins MMP-9 and S-100 showed perioperative increase, which was in accordance with intraoperative cerebral injury. The S-100 and NSE plasma levels remained within normal values. The level of NSE even decreased, probably due to intraoperative fluid infusion. Our study showed that the use of neuroprotective anesthesia can reduce neuroinflammation. The study also highlights the perioperative expression of proteins MMP-9 and S-100, which might be useful as biomarkers of cerebral injury in the context of balanced anesthesia during major abdominal surgery.</p>","PeriodicalId":7122,"journal":{"name":"Acta Chimica Slovenica","volume":"72 1","pages":"45-51"},"PeriodicalIF":1.3,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cennet Ozay, Nuray Sarac Deveci, Fadime Aydin Kose, Ramazan Mammadov
{"title":"Two unexplored Saponaria species from Türkiye: Phenolic composition and a pharmacologic potential.","authors":"Cennet Ozay, Nuray Sarac Deveci, Fadime Aydin Kose, Ramazan Mammadov","doi":"10.17344/acsi.2024.9076","DOIUrl":"10.17344/acsi.2024.9076","url":null,"abstract":"<p><p>To investigate the total secondary metabolite amounts, phenolic profile, antioxidant activity, acute toxicity, cytotoxic, and wound-healing effects of the aerial parts of Saponaria kotschyi (endemic) and Saponaria pumilio extracts. The total phenolic, flavonoid, saponin, and tannin contents; antioxidant activity (via six different methods, including β-carotene/linoleic acid, DPPH, ABTS, FRAP, phosphomolybdenum, and metal chelating assays); phenolic constituents in the extracts (HPLC method); acute toxicity (brine shrimp lethality test); antiproliferative effects on human cervical carcinoma (HeLa) and human neuroblastoma (SH-SY5Y) cancer cell lines (MTT assay); and the effects on wound healing in healthy mouse fibroblast cells (NIH-3T3) through an in vitro scratch assay were evaluated. The methanol extract of S. kotschyi demonstrated higher concentrations of secondary metabolites and antioxidant activity than S. pumilio. Both species predominantly contained caffeic acid, 2,5-dihydroxybenzoic acid, and epicatechin, though S. pumilio had a notably higher caffeic acid content. Additionally, S. kotschyi extract showed greater cytotoxicity against HeLa and SH-SY5Y cancer cells, while S. pumilio exhibited greater wound-healing efficacy. Two previously unexplored Saponaria species reveal a remarkable richness in secondary metabolites and potent antioxidant activity. Given their diverse phenolic constituents, these species emerge as promising candidates for therapeutic applications in cervical cancer and neuroblastoma, as well as playing a potentially critical role in tissue repair and regeneration-areas that merit further in-depth investigation.</p>","PeriodicalId":7122,"journal":{"name":"Acta Chimica Slovenica","volume":"72 1","pages":"96-106"},"PeriodicalIF":1.2,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143661841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Merve Argon, Temine Sabudak, Buse Nur Yildirim, Bahadır Batar, Hakime Hulya Orak, Mehmet Yabas, Ayten Bostanci, Hilmican Caliskan
{"title":"Chemical profile, antiproliferative and antioxidant activities of Genista januensis subsp. lydia (Boiss.) Kit Tan & Ziel (Fabaceae).","authors":"Merve Argon, Temine Sabudak, Buse Nur Yildirim, Bahadır Batar, Hakime Hulya Orak, Mehmet Yabas, Ayten Bostanci, Hilmican Caliskan","doi":"10.17344/acsi.2024.8957","DOIUrl":"10.17344/acsi.2024.8957","url":null,"abstract":"<p><p>The aim of this study was to investigate the anticancer and antioxidant activities of the G. januensis subsp. lydia (Fabaceae) and to isolate the phytochemical compounds responsible for these activities. In this study, the G. januensis plant was extracted by maceration with increasing polarity and the anticancer activity of the crude extracts was investigated by performing cytotoxicity, apoptosis and cell cycle analyses. In addition, the total phenolic/flavonoid content was determined in crude extracts and antioxidant activity. According to the results of anticancer and antioxidant activities, the EtOAc extract was found to have the highest activity and this extract was selected for an isolation study. All purified flavonoid compounds from the EtOAc extract were elucidated using 1D and 2D NMR and mass spectroscopy methods and compared with the literature data. A new biflavonoid (4) was isolated together with three known isoflavonoids (Genistein (1), Genistin (2) and 4'-hydroxy isoflavon (3)) from Genista januensis subsp. lydia (Fabaceae). MTT analysis of the compounds 2, 3, and 4 was utilized to evaluate the anticancer activity. Moreover, compound 4 had antioxidant activities determined. These findings suggest that G. januensis subsp. lydia has potential for further study as a natural source of antiproliferative and antioxidant agents.</p>","PeriodicalId":7122,"journal":{"name":"Acta Chimica Slovenica","volume":"72 1","pages":"52-62"},"PeriodicalIF":1.2,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143661991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Syntheses, Crystal Structures and Characterization of Two New Lanthanide Mercury Halide Compounds.","authors":"Xi-Yu Shao, Hao-Dong Liu, Long-Hua Zeng, Yu-Yue Xu, Wen-Tong Chen, Cheng Liu, Sheng-Ping Dai, Chang-Wang Pan","doi":"10.17344/acsi.2024.8937","DOIUrl":"https://doi.org/10.17344/acsi.2024.8937","url":null,"abstract":"<p><p>Two new lanthanide mercury halide compounds with isonicotinic acid as a ligand, namely, [Gd(HIA)2(IA)(H2O)2(HgCl2)]n(nHgCl4)·3nH2O (1) (HIA = isonicotinic acid) and {[Nd(HIA)3(DMF)(H2O)]n}[(Hg4Br11)n](2HgBr2)(nBr)·nH3O·0.5nH2O (2) (DMF = N,N'-Dimethylformamide), were synthesized by means of solvothermal reactions and characterized by single-crystal X-ray diffraction. Compound 1 is characterized by a two-dimensional (2-D) layer-like structure, while compound 2 features a one-dimensional (1-D) chain-like structure. The lanthanide ions in both compounds are eight coordination and show a square antiprism geometry. The mercury ions exhibit various coordination motifs. Compound 1 shows a ultraviolet upconversion photoluminescence emission, while compound 2 displays red photoluminescence. The photoluminescence emissions come from the characteristic emissions of the 4f electron intrashell transitions of the 6P7/2 → 8S7/2 of the Gd3+ ions in compound 1 and the 4F9/2 → 4I9/2, 4F7/2 + 4S3/2→ 4I9/2, 4F5/2 + 2H9/2→ 4I9/2, 4F3/2 → 4I9/2 of the Nd3+ ions in compound 2. Compound 2 has CIE (Commission Internationale de I'Éclairage) chromaticity coordinates (0.7142, 0.2857) and its CCT (correlated color temperature) is 138224 K. Solid-state UV/Vis diffuse reflectance spectra discovered that their semiconductor band gaps are 3.12 eV and 3.23 eV, respectively.</p>","PeriodicalId":7122,"journal":{"name":"Acta Chimica Slovenica","volume":"71 4","pages":"685-695"},"PeriodicalIF":1.3,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"DRUŠTVENE VESTI IN DRUGE AKTIVNOSTI SOCIETY NEWS, ANNOUNCEMENTS, ACTIVITIES.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7122,"journal":{"name":"Acta Chimica Slovenica","volume":"71 4","pages":"S93-S110"},"PeriodicalIF":1.3,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}