巨孢菌的生物活性、化学成分及分子对接。

IF 1.2 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Acta Chimica Slovenica Pub Date : 2025-02-05 DOI:10.17344/acsi.2024.9077

Abdulrahaman Mahmoud Dogara, Sawsan Sadiq Al-Rawi, Ateeq Ahmed Al-Zahrani, Abubakar Abdullahi Lema, Aisha Abdullahi Mahmud, Hasan Nudin Nur Fatihah, Iliyasu Uwaisu, Hussain Daifallah Almalki

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引用次数: 0

摘要

本研究分析了非洲热带干旱国家的多年生野生丛草Urelytrum giganteum Pilg的溶剂提取，以确定其抗氧化潜力、化学成分、近似分析、抗菌功效和分子对接。乙醇提取物在各种试验中显示出最高的抗氧化活性，并对所有测试菌株显示出最显著的抗菌活性。鉴定的植物化学物质包括生物碱、类黄酮、皂苷、酚类物质、单宁、碳水化合物、萜烯和c -糖苷。大多数植物化学物质表现出显著的抑制活性，其中豆甾醇表现出最高的抑制得分。

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Biological activities, chemical composition and molecular docking of Urelytrum giganteum Pilg.

This study analyzed solvent extractions of Urelytrum giganteum Pilg, a perennial wild tufted grass in dry tropical African countries, to determine its antioxidant potential, chemical composition, proximate analysis, antimicrobial efficacy, and molecular docking. The ethanolic extract showed the highest antioxidant activity across various assays and showed the most substantial antibacterial activity against all tested bacterial strains. The phytochemicals identified included alkaloids, flavonoids, saponins, phenolic substances, tannins, carbohydrates, terpenes, and C-glycosides. The majority of the phytochemicals demonstrated notable inhibitory activity, with Stigmasterol showing the highest inhibition score.

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来源期刊

Acta Chimica Slovenica 化学-化学综合

CiteScore

2.50

自引率

25.00%

发文量

审稿时长

1.0 months

期刊介绍： Is an international, peer-reviewed and Open Access journal. It provides a forum for the publication of original scientific research in all fields of chemistry and closely related areas. Reviews, feature, scientific and technical articles, and short communications are welcome.