Micro and Nano Systems Letters最新文献_第6页

Quantitative image analysis of thrombus formation in microfluidic in-vitro models 微流体体外模型中血栓形成的定量图像分析

IF 3.6

Micro and Nano Systems Letters Pub Date : 2022-12-20 DOI: 10.1186/s40486-022-00166-3

Ji-Seob Choi, Dong-Hwi Ham, Jung-Hyun Kim, Helem Betsua Flores Marcial, Pyeong-Ho Jeong, Jin-Ho Choi, Woo-Tae Park

引用次数: 2

Simulation of Germanium-on-Nothing cavity’s morphological transformation using deep learning 基于深度学习的锗空腔形态变换模拟

IF 3.6

Micro and Nano Systems Letters Pub Date : 2022-12-08 DOI: 10.1186/s40486-022-00164-5

Jaewoo Jeong, Taeyeong Kim, Jungchul Lee

{"title":"Simulation of Germanium-on-Nothing cavity’s morphological transformation using deep learning","authors":"Jaewoo Jeong, Taeyeong Kim, Jungchul Lee","doi":"10.1186/s40486-022-00164-5","DOIUrl":"10.1186/s40486-022-00164-5","url":null,"abstract":"<div><p>Unique self-assembled germanium structures known as Germanium-on-Nothing (GON), which are fabricated via annealing, have buried multiscale cavities with different morphologies. Due to their unique sub-surface morphologies, GON structures are utilized in various applications including optoelectronics, micro-/nanoelectronics, and precision sensors. Each application requires different cavity shapes, and a simulation tool is able to determine the required annealing duration for a given shape. However, a theoretical simulation inevitably requires simplifications which limit its accuracy. Herein, to resolve such dependence on simplification, we introduce a deep learning-based method for simulating the transformation of sub-surface morhpology of GON over annealing. Namely, a deep learning model is trained to predict GON’s morphological transformation from 4 cross-sectional images acquired at different annealing times. Compared to conventional simulation schemes, our proposed deep learning-based simulation method is not only computationally efficient (<span>(sim 10)</span> min) but also physically accurate with its use of empirical data.</p></div>","PeriodicalId":704,"journal":{"name":"Micro and Nano Systems Letters","volume":"10 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2022-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://mnsl-journal.springeropen.com/counter/pdf/10.1186/s40486-022-00164-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49211037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wet anisotropic etching characteristics of Si{111} in NaOH-based solution for silicon bulk micromachining 硅本体微加工用硅{111}在NaOH溶液中的湿各向异性刻蚀特性

IF 3.6

Micro and Nano Systems Letters Pub Date : 2022-12-01 DOI: 10.1186/s40486-022-00162-7

S. Purohit, V. Swarnalatha, A. K. Pandey, P. Pal

{"title":"Wet anisotropic etching characteristics of Si{111} in NaOH-based solution for silicon bulk micromachining","authors":"S. Purohit, V. Swarnalatha, A. K. Pandey, P. Pal","doi":"10.1186/s40486-022-00162-7","DOIUrl":"10.1186/s40486-022-00162-7","url":null,"abstract":"<div><p>Silicon bulk micromachining is extensively employed method in microelectromechanical systems (MEMS) for the formation of freestanding (e.g., cantilevers) and fixed (e.g., cavities) microstructures. Wet anisotropic etching is a popular technique to perform silicon micromachining as it is low-cost, scalable, and suitable for large scale batch processing, which are the major factors considered in the industry to reduce the cost of the product. In this work, we report the wet anisotropic etching characteristics of Si{111} in sodium hydroxide (NaOH) without and with addition of hydroxylamine (NH<sub>2</sub>OH). 10M NaOH and 12% NH<sub>2</sub>OH are used for this study. The effect of NH<sub>2</sub>OH is investigated on the etch rate, etched surface roughness and morphology, and the undercutting at mask edges aligned along < 112 > direction. These are the major etching characteristics, which should be studied in a wet anisotropic etchant. A 3D laser scanning microscope is utilized to measure the surface roughness, etch depth, and undercutting length, while the etched surface morphology is examined using a scanning electron microscope (SEM). The incorporation of NH<sub>2</sub>OH in NaOH significantly enhances the etch rate and the undercutting at the mask edges that do not consist of {111} planes. To fabricate freestanding structure (e.g., microcantilever) on Si{111} wafer, high undercutting at < 112 > mask edges is desirable to reduce the release time. Moreover, the effect of etchant age on the abovementioned etching characteristics are investigated. The etch rate and undercutting reduce significantly with the age of the modified NaOH. The present paper reports very interesting results for the applications in wet bulk micromachining of Si{111}.</p></div>","PeriodicalId":704,"journal":{"name":"Micro and Nano Systems Letters","volume":"10 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://mnsl-journal.springeropen.com/counter/pdf/10.1186/s40486-022-00162-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47518224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of channel height on the critical particle diameter in a deterministic lateral device 确定性横向装置中通道高度对临界颗粒直径的影响

IF 3.6

Micro and Nano Systems Letters Pub Date : 2022-11-30 DOI: 10.1186/s40486-022-00163-6

Jae Hyun Bae, Alexander Zhbanov, Sung Yang

引用次数: 1

Design and simulation of a neural interface based on a microfluidic flexible interconnection cable for chemical delivery 基于微流体柔性互连电缆的神经接口设计与仿真

IF 3.6

Micro and Nano Systems Letters Pub Date : 2022-11-19 DOI: 10.1186/s40486-022-00161-8

Yoo Na Kang, Jun-Uk Chu, Kang-Ho Lee, Yongkoo Lee, Sohee Kim

引用次数: 0

Influence of multiple stenoses on thrombosis formation: an in vitro study 多种狭窄对血栓形成的影响：一项体外研究

IF 3.6

Micro and Nano Systems Letters Pub Date : 2022-11-19 DOI: 10.1186/s40486-022-00159-2

Helem B. Flores Marcial, Jiseob Choi, Donghwi Ham, Junghyun Kim, Pyeongho Jeong, Jinho Choi, Woo-Tae Park

{"title":"Influence of multiple stenoses on thrombosis formation: an in vitro study","authors":"Helem B. Flores Marcial, Jiseob Choi, Donghwi Ham, Junghyun Kim, Pyeongho Jeong, Jinho Choi, Woo-Tae Park","doi":"10.1186/s40486-022-00159-2","DOIUrl":"10.1186/s40486-022-00159-2","url":null,"abstract":"<div><p>Multiple lesions in the same vessel is one of the most common situations found in patients suffering from cardiovascular diseases, this complicates not only the assessment of the severity of each one but also their treatment. To date, the effect of multiple stenoses on different parameters has been simulated by numerical studies. Few others have implemented in vitro platforms for their investigation. However, visualization of thrombosis formation in this kind of lesion is still needed. This in vitro study monitors the formation of thrombus inside microchannels having one, two, and three stenoses. Whole blood was perfused through each channel at high shear rates (> 12,000 s<sup>−1</sup>), generating thrombosis. Flow changes across each lesion as well as the final percentage of aggregations were monitored. Thus, the location where total occlusion could be produced was found to be the first stenosis for all the cases. Less flow reaching the second and third stenoses was observed which demonstrates that aggregations were growing at the first one. This was verified by measuring the percentage of aggregations at the end of the test.</p></div>","PeriodicalId":704,"journal":{"name":"Micro and Nano Systems Letters","volume":"10 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2022-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://mnsl-journal.springeropen.com/counter/pdf/10.1186/s40486-022-00159-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47422387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Highly stretchable strain sensors with improved sensitivity enabled by a hybrid of carbon nanotube and graphene 由碳纳米管和石墨烯混合而成的具有提高灵敏度的高拉伸应变传感器

IF 3.6

Micro and Nano Systems Letters Pub Date : 2022-11-12 DOI: 10.1186/s40486-022-00160-9

Leilei Wang, Jungwook Choi

{"title":"Highly stretchable strain sensors with improved sensitivity enabled by a hybrid of carbon nanotube and graphene","authors":"Leilei Wang, Jungwook Choi","doi":"10.1186/s40486-022-00160-9","DOIUrl":"10.1186/s40486-022-00160-9","url":null,"abstract":"<div><p>The development of high-performance strain sensors has attracted significant attention in the field of smart wearable devices. However, stretchable strain sensors usually suffer from a trade-off between sensitivity and sensing range. In this study, we investigate a highly sensitive and stretchable piezoresistive strain sensor composed of a hybrid film of 1D multi-walled carbon nanotube (MWCNT) and 2D graphene that forms a percolation network on Ecoflex substrate by spray coating. The mass of spray-coated MWCNT and graphene and their mass ratio are modulated to overcome the trade-off between strain sensitivity and sensing range. We experimentally found that a stable percolation network is formed by 0.18 mg of MWCNTs (coating area of 200 mm<sup>2</sup>), with a maximum gauge factor (GF) of 1,935.6 and stretchability of 814.2%. By incorporating the 0.36 mg of graphene into the MWCNT film (i.e., a mass ratio of 1:2 between MWCNT and graphene), the GF is further improved to 12,144.7 in a strain range of 650–700%. This high GF is caused by the easy separation of the graphene network under the applied strain due to its two-dimensional (2D) shape. High stretchability originates from the high aspect ratio of MWCNTs that bridges the randomly distributed graphenes, maintaining a conductive network even under sizeable tensile strain. Furthermore, a small difference in work function between MWCNT and graphene and their stable percolation network enables sensitive UV light detection even under a significant strain of 300% that cannot be achieved by sensors composed of MWCNT- or graphene-only. The hybrids of MWCNT and graphene provide an opportunity to achieve high-performance stretchable devices.</p></div>","PeriodicalId":704,"journal":{"name":"Micro and Nano Systems Letters","volume":"10 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2022-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://mnsl-journal.springeropen.com/counter/pdf/10.1186/s40486-022-00160-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49601489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

In-vivo recording of sensory signals from peripheral nerves using flexible 3D neural electrodes 利用柔性三维神经电极在体内记录周围神经的感觉信号

IF 3.6

Micro and Nano Systems Letters Pub Date : 2022-11-02 DOI: 10.1186/s40486-022-00158-3

Byungwook Park, Jae-Won Jang, Sohee Kim

{"title":"In-vivo recording of sensory signals from peripheral nerves using flexible 3D neural electrodes","authors":"Byungwook Park, Jae-Won Jang, Sohee Kim","doi":"10.1186/s40486-022-00158-3","DOIUrl":"10.1186/s40486-022-00158-3","url":null,"abstract":"<div><p>To overcome the limitations of muscle-based prostheses, studies on nerve-based prostheses for sensory feedback have recently been reported. To develop such prostheses, intrafascicular electrodes, a type of peripheral nerve interface, are essentially used to connect the nervous system and external systems. Through these electrodes, sensory feedback to induce sensations in patients is possible. To evoke natural sensations, precise recordings of nerve signals should precede sensory feedback, in order to identify patterns of sensory signals in the nerve and to mimic these patterns in stimulating the nerve. For this purpose, we previously developed a PDMS-based flexible penetrating microelectrode array (FPMA). In the current study, we verified the ability of the FPMA to record sensory nerve signals. The FPMA implanted in the rabbit sciatic nerve was able to record spontaneous neural signals, and the recorded signals were separated into action potential units. In addition, sensory nerve signals synchronized with ankle movement were successfully recorded, demonstrating that the FPMA is a useful peripheral neural interface capable of recording high-resolution sensory signals.</p></div>","PeriodicalId":704,"journal":{"name":"Micro and Nano Systems Letters","volume":"10 1","pages":""},"PeriodicalIF":3.6,"publicationDate":"2022-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://mnsl-journal.springeropen.com/counter/pdf/10.1186/s40486-022-00158-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41725678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A 3D-printed pneumatic dispenser with monitoring droplet ejection 具有液滴喷射监测功能的3D打印气动分配器

IF 3.6

Micro and Nano Systems Letters Pub Date : 2022-10-31 DOI: 10.1186/s40486-022-00157-4

Dong Kwan Kang, Jeong Woo Park, Sangmin Lee

引用次数: 0

Methods to analyze extracellular vesicles at single particle level 方法在单颗粒水平上分析细胞外囊泡

IF 3.6

Micro and Nano Systems Letters Pub Date : 2022-10-28 DOI: 10.1186/s40486-022-00156-5

Yongmin Kwon, Jaesung Park

引用次数: 5