ACS Applied Nano Materials最新文献

{"title":"Metal−Organic Framework-Derived Sulfide−Selenide Heterostructure as an Efficient Electrocatalyst for Alkaline Hydrogen Evolution Reaction","authors":"Zubaira Manzoor,&nbsp;Saifullah Lone,&nbsp;Kowsar Majid","doi":"10.1021/acsanm.6c02860","DOIUrl":"https://doi.org/10.1021/acsanm.6c02860","url":null,"abstract":"<p>Heterostructure engineering has emerged as an effective strategy for developing efficient and durable non-precious-metal electrocatalysts for the hydrogen evolution reaction (HER) to enable sustainable hydrogen production. However, the development of MOF-derived heterostructures remains relatively underexplored, despite the unique opportunities offered by interfacial engineering to modulate electronic structures and accelerate catalytic kinetics. In this work, we designed a strategy to construct a heterostructured electrocatalyst comprising zeolitic imidazolate framework (ZIF)-derived Co₃S₄ coupled with Ni₃Se₄. The MOF-derived Co₃S₄ provides abundant catalytically active sites and structural stability, while Ni₃Se₄ enhances electrical conductivity and facilitates hydrogen adsorption/desorption kinetics. The intimate Co₃S₄/Ni₃Se₄ heterointerface generates strong electronic interactions that effectively modulate the electronic structure and accelerate interfacial charge transfer. As a result, the Co₃S₄/Ni₃Se₄ heterostructure exhibits superior HER activity in an alkaline electrolyte, requiring only an overpotential of 205 mV to reach a current density of 10 mA cm⁻² and displaying a low Tafel slope of 63 mV dec⁻¹. Moreover, the catalyst demonstrates excellent electrochemical durability during prolonged operation. The enhanced catalytic performance is attributed to the synergistic coupling between Co₃S₄ and Ni₃Se₄, which promotes water dissociation and optimizes hydrogen evolution kinetics. This study underscores the effectiveness of heterointerface engineering and MOF-derived architectures in the design of high-performance, earth-abundant electrocatalysts for sustainable hydrogen generation.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"9 40","pages":"18541–18552"},"PeriodicalIF":5.8,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149153279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nisin Z-Loaded Chitosan-Pectin Coated Liposomes for Controlled Release and Antibiofilm Activity","authors":"Minh Quan Ho,&nbsp;Nam-Son Dinh-Ngoc,&nbsp;Quynh-Anh Vu-Yen,&nbsp;Dang Nguyen Nha Khanh,&nbsp;Tan Anh Nguyen,&nbsp;Ngoc Thuy Trang Le","doi":"10.1021/acsanm.6c01975","DOIUrl":"https://doi.org/10.1021/acsanm.6c01975","url":null,"abstract":"<p>Pathogenic biofilms and complex biological environments significantly limit the therapeutic efficacy of antimicrobial peptides such as Nisin Z due to rapid degradation and poor penetration. In this study, we developed a Nisin Z-loaded chitosan-pectin coated liposome (LCPN) as a lipid-polymer hybrid nanosystem to overcome these limitations. The optimized LCP formulation exhibited an average particle size of 278.4 ± 3.1 nm, a polydispersity index of 0.229 ± 0.326, and a surface charge of −28.7 ± 0.8 mV. Furthermore, the nanosystem achieved a high encapsulation efficiency of 63.84% and demonstrated a sustained release profile, delivering 63.64% of Nisin Z over 72 h. In addition, LCPN exhibited a sustained release profile, contributing to prolonged antimicrobial activity. Functionally, the LCPN system demonstrated strong antibiofilm efficacy (88.13% at 350 μg/mL), effectively enhancing disruption of pre-formed biofilms and significantly reducing bacterial biomass compared to free Nisin Z. Notably, <em>in vivo</em> evaluation in a shrimp infection model showed enhanced antibacterial performance in hemolymph, resulting in improved survival rates (83.3% at 14 days post-infection) and growth performance following <em>Vibrio</em> challenge. These findings suggest that the chitosan-pectin coated liposomal platform is a highly stable and controlled-release delivery system for antimicrobial peptides, offering a promising and targeted strategy for disease management in aquaculture.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"9 40","pages":"18376–18389"},"PeriodicalIF":5.8,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149152936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hollow Coral-like Black g-C3N4 Nanoparticles for Photothermal-Assisted Photocatalytic Hydrogen Generation","authors":"Tianguang Liang,&nbsp;Lijing Wang,&nbsp;Pengnian Shan,&nbsp;Yuhan Wang,&nbsp;Pengyu Kang,&nbsp;Feng Guo,&nbsp;Weilong Shi","doi":"10.1021/acsanm.6c03134","DOIUrl":"https://doi.org/10.1021/acsanm.6c03134","url":null,"abstract":"<p>Graphitic carbon nitride (g-C₃N₄) is a promising photocatalyst for energy and environmental applications due to its stability and intrinsic activity, but it suffers from limited visible-light absorption and poor light harvesting. Herein, a porous, highly crystalline black g-C₃N₄ (H-BCN) was synthesized <em>via</em> a facile one-step molten salt calcination strategy. This material exhibits significantly enhanced light absorption and a pronounced photothermal effect, greatly boosting photocatalytic H₂ production. The optimal H-BCN achieved a H₂ evolution rate of 12.71 mmol g⁻¹ h⁻¹ under the full-spectrum illumination of a 300 W Xenon lamp, which is 1.94 times that of pristine yellow g-C₃N₄ (YCN) and exhibited a quantum efficiency (AQE) of 9.4% at 420 nm in water. The enhanced performance stems from four key factors: (i) laver-derived biomass carbon incorporated during calcination produces black g-C₃N₄ with improved photon harvesting and photothermal conversion; (ii) coral-like porous cavities promote multiple internal reflections of light, increasing absorption efficiency; (iii) molten salt synthesis raises crystallinity and introduces K/Na intercalation between layers, creating doping channels that accelerate charge transport; and (iv) surface functional groups on biochar improve hydrophilicity, facilitating catalyst−water interaction. This work provides a rational design strategy for developing black g-C₃N₄ photocatalysts with superior light absorption and photothermal-assisted photocatalytic hydrogen generation.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"9 40","pages":"18625–18636"},"PeriodicalIF":5.8,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149153149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive Regulation of Metal Centers and Electron Withdrawing Groups in Ligands of Metalloporphyrins Boosts NO Electrocatalytic Reduction Reaction","authors":"Zong-Hai Li,&nbsp;Yu-Xing Ren,&nbsp;Rui-Xiang Wang,&nbsp;Yang-Xin Yu","doi":"10.1021/acsanm.6c03153","DOIUrl":"https://doi.org/10.1021/acsanm.6c03153","url":null,"abstract":"<p>The electrochemical transformation of nitric oxide into ammonia (NH₃) presents a promising strategy for sustainable NH₃ production, offering an environmentally friendly alternative to address atmospheric NO pollution. This study establishes a database of metalloporphyrins having two-dimensional porphyrinic covalent organic frameworks with isolated transition-metal-N₄ sites. The transition metal porphyrin units (TMPh) are interconnected through conjugated linker environments (DX) containing C, N, O, or F atoms, denoted as TMPh-DX (X = C, N, O, and F). We systematically investigate the intrinsic relationships between NORR catalytic performance and key catalyst characteristics using interpretable machine-learning (ML) on the basis of the “four-plus-one” step high-throughput screening results from density functional theory (DFT). Using this framework, we initially screened 15 promising catalysts from a pool of 112 candidates. A comprehensive analysis of these 15 candidates identified six computationally promising NORR candidates with limiting potentials below −0.1 V, suggesting a joint influence of transition metal centers and electron withdrawing groups in ligands. To overcome the limitations of the “black box” in machine learning, we employed SHAP analysis coupled with SISSO symbolic regression, to identify key factors influencing the Gibbs energy changes in the three fundamental steps. Symbolic expressions were derived to predict Gibbs energy variations in the three reaction steps. This workflow can be extended to screen catalysts for other electrochemical reactions efficiently.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"9 40","pages":"18637–18653"},"PeriodicalIF":5.8,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149153140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multifunctional Nanoparticles for Imaging-Guided Tumor Phototherapy via ONOO- Mediated Tumor Microenvironment Remodeling","authors":"Shudi Liu,&nbsp;Qingzhen Hu,&nbsp;Huafei Liu,&nbsp;Weili Si","doi":"10.1021/acsanm.6c03534","DOIUrl":"https://doi.org/10.1021/acsanm.6c03534","url":null,"abstract":"<p>The highly condensed extracellular matrix characteristic of tumor tissues significantly impedes the transport and accumulation of fluorescent probes and therapeutic drugs, ultimately compromising the accuracy of tumor detection and the effectiveness of therapeutic interventions. Different from conventional fluorescence imaging, afterglow imaging is characterized by long-lasting luminescence that persists following the cessation of external photoexcitation, which has earned it increasing research attention in the field of biomedical imaging. However, currently reported afterglow probes generally suffer from weak luminescence signals and complicated component compositions. To address these issues, a multifunctional nanoparticle, mMB@DPA has been designed and constructed by self-assembling a photosensitizer with <span>l</span>-arginine loaded onto DSPE-PEG₂₀₀₀-NH₂. The resulting nanoparticles possess multiple functions, including hydrogen peroxide-responsive nitric oxide (NO) release, afterglow imaging, pronounced reactive oxygen species (ROS) generation capability and excellent photothermal conversion efficiency, enabling fluorescence-guided tumor visualization during phototherapy. In response to elevated intracellular hydrogen peroxide or ROS generated upon light irradiation, mMB@DPA rapidly produces abundant NO on its surface. Upon 660 nm laser irradiation, the nanoparticles concurrently produce ROS and hyperthermia. The generated ROS further reacts with NO to form peroxynitrite (ONOO¯), a potent oxidative and nitrative mediator. ONOO¯ generation not only upregulates matrix metalloproteinase (MMP) expression to facilitate nanoparticle penetration and tumor accumulation, but also inhibits heat-shock protein (HSP) expression, which potentially diminishes the thermotolerance of tumor cells. Using a subcutaneous tumor model, we verified that ONOO¯-mediated synergistic phototherapy achieves markedly improved antitumor therapeutic efficacy.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"9 40","pages":"18911–18924"},"PeriodicalIF":5.8,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149153130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lignin-Mediated In Situ Silver Nanoparticle Bioactive Conductive Hydrogels for Regenerative Wound Healing, Energy Harvesting, and Motion Sensing Applications","authors":"Azma Fakhar,&nbsp;Sadaf Mearaj,&nbsp;Muhammad Ajaz Ahmed,&nbsp;Sungok Hong,&nbsp;Na Yun Kim,&nbsp;Mirza Mahmood Baig,&nbsp;Seung Goo Lee,&nbsp;Hyo Jin Kim,&nbsp;Tae Min Kim,&nbsp;Joon Weon Choi","doi":"10.1021/acsanm.6c02138","DOIUrl":"https://doi.org/10.1021/acsanm.6c02138","url":null,"abstract":"<p>In this study, lignin−silver nanoparticle−polyacrylamide (lignin−AgNP−PAM) hybrid hydrogels were developed through persulfate-initiated free-radical polymerization for wound dressing, energy harvesting, and motion-sensing applications. Kraft lignin and milled wood lignin were incorporated at two different loadings to evaluate the formulation-dependent physicochemical, biological, and electromechanical performance. Lignin acted as a bioactive component and was proposed to assist the in situ formation and stabilization of AgNPs through its redox-active phenolic groups. FTIR analysis supported lignin incorporation and molecular interactions within the PAM network, while XRD indicated reduced semi-crystallinity following lignin addition and possible metallic silver formation in selected samples. Dynamic light scattering revealed lignin−silver hybrid particles with Z-average sizes ranging from 74 nm to 298 nm and polydispersity indices of 0.28−0.39. The hydrogels exhibited strong antioxidant activity, reaching approximately 88% ABTS radical-scavenging efficiency, and produced more than 87% antibacterial inhibition against <em>Escherichia coli</em> and <em>Staphylococcus aureus</em> under the tested conditions. Human dermal fibroblast viability remained above 85%, while M3 showed the highest viability and the lowest hemolysis, approximately 100% and 10%, respectively. Scratch assays demonstrated enhanced fibroblast migration, with K3 and M2 achieving approximately 90% and 92% wound closure, respectively, after 48 h. Proof-of-concept electromechanical testing of K2 generated triboelectric output up to approximately 28 V and distinct deformation-responsive signals near 1 V during finger motion. Overall, the hydrogels showed formulation-dependent trade-offs between bioactivity, blood compatibility, and electrical performance, supporting further optimization for wound contact and wearable sensing applications.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"9 40","pages":"18390–18406"},"PeriodicalIF":5.8,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149153087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CuO Nanoparticles Supported on NiFe2O4 Nanorods as a Visible-Light Photocatalyst for the Click Reaction","authors":"Milad Mohammadi Rasooll,&nbsp;Hassan Sepehrmansourie,&nbsp;Mohammad Ali Zolfigol,&nbsp;Saeid Azizian","doi":"10.1021/acsanm.5c05584","DOIUrl":"https://doi.org/10.1021/acsanm.5c05584","url":null,"abstract":"<p>Embedding different metal oxide nanoparticles on calcined metal-organic frameworks (MOFs) with bimetallic structures is a smart strategy for the architecture of heterogeneous nanostructures. Herein, the organization of CuO nanoparticles on NiFe₂O₄ nanorods, which themselves are calcined by MIL-88B(Fe₂/Ni) as a bimetallic MOF, was utilized for the click reaction under visible-light irradiation (λ &gt; 420 nm). In the first step, MIL-88B(Fe₂/Ni) nanorods were prepared as a host bimetallic MOF by a solvothermal method. The NiFe₂O₄ nanorods were obtained via the calcination of MOFs. Then, CuO was organized on the NiFe₂O₄ nanorods to obtain a type of magnetic heterogeneous NiFe₂O₄@CuO photocatalyst with an S-scheme heterojunction system. Under visible-light irradiation, this heterogeneous nanostructure acts as a highly efficient photocatalyst for the formation of triazole rings via a click reaction, which can compete with the best reported photocatalyst systems. The obtained results showed that the presence of Ni and Fe metals in the presence of CuO nanoparticles can significantly enhance the separation of photo-generated electron-hole pairs and then enhance their photocatalytic performance. Consistent with the results of photoelectrochemical findings such as electron paramagnetic resonance, Mott-Schottky, and UV-visible diffuse-reflectance spectra spectrum, the appropriate band gap structures of this nanorod structure ensure the generation of electrons required for the reaction under visible-light irradiation. The present study can provide insights into the calcination of MOFs to create heterogeneous structures as well as develop S-scheme heterojunction materials for click reactions and other organic reactions under visible-light irradiation.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"9 40","pages":"18339–18350"},"PeriodicalIF":5.8,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149153089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional Composite Modification of Cubic CeO2 Nanoparticles for Enhanced Dispersion and Polishing","authors":"Lulu Wang,&nbsp;Yunhui Shi,&nbsp;Yongxin Wang,&nbsp;Yao Xu,&nbsp;Chang Li,&nbsp;Long Zheng,&nbsp;Boyao Liu,&nbsp;Heqi Li","doi":"10.1021/acsanm.6c03632","DOIUrl":"https://doi.org/10.1021/acsanm.6c03632","url":null,"abstract":"<p>To address agglomeration, poor dispersion stability, and the trade-off between removal rate and surface quality of nano-CeO₂ abrasives in chemical mechanical polishing (CMP), this work focuses on cubic CeO₂ nanoparticles (C−CeO₂) with exposed (100) facets and systematically compares sodium dodecyl sulfate (SDS)-based composite modifications with 3-glycidyloxypropyltrimethoxysilane (GPTMS), polyvinyl alcohol (PVA), oleic acid (OA), and 2-methylpiperazine (2 MP). Comprehensive characterizations were used to elucidate the structure−property relationships between functional groups, interfacial interactions, and polishing performance. Results show that SDS-based composite modification suppresses nanoparticle agglomeration through synergistic electrostatic and steric effects. Among the four systems, C−CeO₂-SDS-GPTMS exhibits the best dispersion, wettability, and Ce³⁺ retention due to stable Si−O−Ce bonds, achieving a material removal rate (MRR) of 3230 Å/min (∼52% increase) and an ultra-low Sq of 0.0321 nm on a 5 × 5 μm SiO₂ dielectric layer. The PVA system balances high removal rate and low damage; OA shows stable adsorption but moderate dispersibility, whereas 2 MP exhibits the poorest performance because of weak coordination and severe hydrophobic agglomeration. Overall, the effectiveness of composite modification depends strongly on interfacial bonding strength and hydrophilic-hydrophobic balance. This study provides a systematic theoretical and experimental foundation for designing high-performance nano-CeO₂-based CMP abrasives.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"9 40","pages":"18959–18970"},"PeriodicalIF":5.8,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149153204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ligand−Surface Interactions and Band Structure Engineering in Cd-Doped MAPbI3 Quantum Dots for Photodetector Applications","authors":"Surya Poornachandiran,&nbsp;Pabitra Narayan Samanta,&nbsp;Oussama Oulhakem,&nbsp;Mohammed Majdoub,&nbsp;Jerzy Leszczynski,&nbsp;Ahmed Al-Ostaz,&nbsp;Sasan Nouranian,&nbsp;Dineshkumar Sengottuvelu","doi":"10.1021/acsanm.6c02816","DOIUrl":"https://doi.org/10.1021/acsanm.6c02816","url":null,"abstract":"<p>Cadmium-doped methylammonium lead iodide (MAPbI₃) quantum dots (QDs) offer a promising route to engineer defect states, enhance structural stability, and tune optoelectronic performance, yet their fundamental photophysics, surface chemistry, and ligand interactions remain poorly understood. Here, MAPb_{1−<em>x</em>}Cd_<em>x</em>I₃ QDs (<em>x</em> = 0−0.25) were synthesized at room temperature in a nonpolar solvent using a ligand-mediated transport (LMT) strategy, enabling systematic Cd²⁺ substitution at the B-site. The resulting nanocrystals are highly uniform (∼4 nm) and exhibit absolute photoluminescence quantum yields (PLQY) of up to ∼75%. X-ray diffraction with Rietveld refinement, HRTEM, and XPS confirm substitutional incorporation of Cd²⁺ into the tetragonal (<em>I</em>4/<em>mcm</em>) lattice, with progressive lattice contraction and subtle octahedral distortion. UV−visible absorption, PL emission, and CIE chromaticity analyses reveal a Cd-induced widening of the optical gap near 5 mol % Cd, consistent with trap-state passivation. Temperature-dependent PL between 20 and 70 °C further shows that low-level Cd-substitution suppresses thermal quenching and modifies exciton−phonon coupling, as captured by Varshni analysis. Complementary first-principles calculations establish (i) the binding modes and energetics of oleate and octylammonium ligands on MAPbI₃ surfaces via natural energy decomposition analysis (NEDA), and (ii) the evolution of band dispersion and projected density of states across MAPb_{1−<em>x</em>}Cd_<em>x</em>I₃ from relativistic DFT calculations, including a direct-to-indirect band−gap transition near 20% Cd. Together, experiment and theory provide a coherent mechanistic picture of how Cd-substitution and surface ligand chemistry govern the structural, electronic, and emissive properties of MAPbI₃ QDs, offering design guidelines for compositional engineering of hybrid perovskite nanocrystals for photodetector and related visible-to-near-infrared optoelectronic applications.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"9 40","pages":"18502–18519"},"PeriodicalIF":5.8,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149153275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leaf-Position-Dependent Remodeling of Phyllosphere Microbiome Mediated by Foliar Zinc Sulfide Nanoparticles Drives Tomato Growth","authors":"Jiahui Zhu,&nbsp;Yilei Sun,&nbsp;Xinya Zhan,&nbsp;Jiawei Wang,&nbsp;Xingyu Wang,&nbsp;Wenjie Li,&nbsp;Junsuo Li,&nbsp;Xinhua Zhan","doi":"10.1021/acsanm.6c03679","DOIUrl":"https://doi.org/10.1021/acsanm.6c03679","url":null,"abstract":"<p>Foliar nano-fertilization is emerging as a promising strategy to improve crop performance, yet the microbiome-mediated mechanisms and their dependence on canopy microhabitats remain poorly understood. Here, we prepared ball-milled ZnS nanoparticles (11.6 ± 2.8 nm) and conducted an equimolar Zn foliar experiment (ZnS at 0.6/1.2/2.4 mM; ZnO and ZnSO₄ at matched molarities). ZnS with recommend concentration (1.2 mM) produced the most robust overall plant improvement. 16S rRNA profiling showed that ZnS-induced microbiome restructuring was stronger in epiphytic than endophytic communities. Among epiphytic communities, ZnS induced a pronounced leaf-position-dependent response across top, middle, and bottom leaves, with the strongest remodeling occurring in middle leaves. Middle-leaf epiphytes showed marked dominant-genus turnover, including enrichment of Brevundimonas and elevation of Sphingobacterium with concurrent declines of control-associated Flavobacterium, together with the most pronounced remodeling of predicted functions (e.g., increased pyruvate metabolism and the TCA cycle). This response matched the growth pattern, suggesting that middle-leaf microbiome remodeling may link ZnS nanoparticles application to improved tomato performance. These results firstly identify middle leaves as a key microecological locus of ZnS action and provide a mechanistic basis for selecting an optimal spraying leaf position.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"9 40","pages":"18971–18983"},"PeriodicalIF":5.8,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149152861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}