ACS Applied Nano Materials最新文献

{"title":"Dual Enzyme-Mimic Popcorn-Shaped Copper–Erbium Nanoalloys for Combating Gram-Negative Pathogens and Promoting Wound Healing","authors":"Arbab Ali,&nbsp;Tao Liu,&nbsp;Jiakun Zhang*,&nbsp;Qiaolin Liu,&nbsp;Yufeng Peng,&nbsp;Shengmin Li,&nbsp;Kejian Shi* and Huige Zhou*,&nbsp;","doi":"10.1021/acsanm.4c0685910.1021/acsanm.4c06859","DOIUrl":"https://doi.org/10.1021/acsanm.4c06859https://doi.org/10.1021/acsanm.4c06859","url":null,"abstract":"<p >Nanozymes with intrinsic ROS-generating abilities hold promise as next-generation antimicrobials; however, optimizing their enzyme-mimic efficiency remains a significant challenge. Here, we fabricated popcorn-shaped copper–erbium nanoalloys (CuEr NAs) via a simple one-pot coreduction method, resulting in stabilized nanoconstructs with dual enzyme-mimic activities. We described that CuEr NAs effectively inactivate <i>Escherichia coli</i> (<i>E. coli</i>) by generating intracellular ROS and depleting glutathione (GSH) through the release of copper ions. These ions induced oxidative stress by generating hydroxyl radicals (^•OH) in acidic environments and oxidizing GSH to glutathione disulfide (GSSG), thereby amplifying ROS generation. CuEr NAs exhibited potent antibacterial activity and enhanced wound healing efficacy in an infected wound model by reducing the bacterial load, ameliorating inflammation, and promoting tissue remodeling. Histological analysis showed enhanced collagen deposition and re-epithelialization in wounds treated with CuEr NAs, highlighting their potential as a flexible platform for antimicrobial and regenerative biomedical applications. This study highlights CuEr NAs as a viable platform for antimicrobial applications and provides insights into the fabrication of multifunctional nanoantimicrobials.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 12","pages":"5926–5940 5926–5940"},"PeriodicalIF":5.3,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143714094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanostructured Cobalt Oxide Catalyst with a Three-Dimensional Flower-Like Structure for Photothermal Purification of Formaldehyde","authors":"Jiahai Fan,&nbsp;Jiasheng Wang,&nbsp;Binbin Chang,&nbsp;Man Xie,&nbsp;Baocheng Zhou*,&nbsp;Pengfei Sun and Xiaoping Dong*,&nbsp;","doi":"10.1021/acsanm.5c0015910.1021/acsanm.5c00159","DOIUrl":"https://doi.org/10.1021/acsanm.5c00159https://doi.org/10.1021/acsanm.5c00159","url":null,"abstract":"<p >Formaldehyde (HCHO), an indoor volatile organic compound (VOC), significantly impacts human health, driving the market demand for more effective degradation technologies. Photothermal catalysis offers a sustainable, efficient, and energy-saving solution for indoor HCHO purification. In this study, we investigated the photothermal catalytic efficiency of HCHO using synthesized copper foam (CF)-based monolithic catalysts. By loading nanostructured cobalt oxide with varying morphologies onto the CF surface, it was observed that cobalt oxide with a three-dimensional (3D) flower-like structure exhibited the highest photothermal performance. Under ultraviolet–visible–near-infrared (UV–vis–NIR) light irradiation alone, this structure achieved a surface temperature of 148.5 °C and demonstrated removal efficiencies of 96.5% and 94.6% for 300 ppm of HCHO in batch and fixed-bed reactors, respectively. The high efficiency of HCHO purification is attributed to the enhanced oxygen mobility from the catalyst, which activates the Mars–van Krevelen (MvK) oxidation pathway of the C–H bond at elevated temperatures. Additionally, short-wave light excitation induces electron transitions, initiating a mechanism involving free radical oxidation. This study highlights the potential of conventional transition metal catalysts as efficient photothermal catalysts for indoor air purification.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 12","pages":"6042–6051 6042–6051"},"PeriodicalIF":5.3,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143714005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In-Flight Observation and Surface Oxidation Modification of Tin Oxide Nanoparticles for Gas Sensing Applications","authors":"Calle Preger*,&nbsp;Linnéa Jönsson,&nbsp;Pau Ternero,&nbsp;Mehran Sedrpooshan,&nbsp;Marie Bermeo,&nbsp;Antti Kivimäki,&nbsp;Noelle Walsh,&nbsp;Maria E. Messing,&nbsp;Axel Christian Eriksson and Jenny Rissler*,&nbsp;","doi":"10.1021/acsanm.5c0014410.1021/acsanm.5c00144","DOIUrl":"https://doi.org/10.1021/acsanm.5c00144https://doi.org/10.1021/acsanm.5c00144","url":null,"abstract":"<p >Metal oxide nanoparticles are essential in various applications, and the synthesis through gas-phase generation methods offers a rapid and reliable pathway for nanoparticle production. Yet achieving precise control over their formation remains challenging due to the complex nature of oxidation processes. While bulk oxidation states can be assessed via off-line measurements, the dynamic nature of surface oxidation is more difficult to monitor and optimize in real time. Here, we investigate the surface oxidation state of unsupported tin oxide nanoparticles using an aerosol sample-delivery system and in-flight X-ray photoelectron spectroscopy. This powerful method allows the continuous monitoring of the surface oxidation of the gas-phase generated nanoparticles in real time, avoiding uncertainties associated with postcollection alterations. Tin oxide nanoparticles are widely used in gas sensing and catalytic applications, where the surface oxide layer plays a crucial role in determining their performance. Our findings demonstrate how the surface oxidation state of the free-flying particles can be controlled by adjusting the carrier gas composition, in-flight heating temperature, and particle composition. Specifically, the surface oxides of tin are partially reduced when heated in a slightly reducing atmosphere, and the reduction is further enhanced by forming mixed tin–gold nanoparticles. While previous studies on metal oxide nanoparticles have focused predominantly on bulk properties or off-line analysis, this study employs real-time in-flight X-ray photoelectron spectroscopy to investigate details of the surface oxidation state. Understanding the surface oxidation of metal oxide nanoparticles is essential to optimize processes, such as in-flight coating or subsequent deposition into a protective environment. This approach enables the exploration of direct correlations between generation conditions and surface properties, providing valuable insights into optimizing gas-phase nanoparticle synthesis.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 12","pages":"6004–6013 6004–6013"},"PeriodicalIF":5.3,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsanm.5c00144","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143714067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smart Textile Display with Addressable Quantum Dot Light-Emitting Diode Based on Durable Ultrathin Metal Electrode","authors":"Jiajie Yang,&nbsp;Jeong-Wan Jo,&nbsp;Yoonwoo Kim,&nbsp;Sung-Min Jung*,&nbsp;Sanghyo Lee* and Jong Min Kim,&nbsp;","doi":"10.1021/acsanm.5c0006810.1021/acsanm.5c00068","DOIUrl":"https://doi.org/10.1021/acsanm.5c00068https://doi.org/10.1021/acsanm.5c00068","url":null,"abstract":"<p >We report a fully addressable smart textile display using quantum dot light-emitting diodes (QD-LEDs) featuring a highly durable electrode. The key innovation lies in the development of an ultrathin oxide/metal hybrid structure for the durable electrode, which achieves mechanical bending durability surpassing the indium tin oxide (ITO) electrode. The optimized electrode, composed of MoO₃ and Au, exhibits a transmittance of <i>T</i>₅₅₀ = 81%, while maintaining a sheet resistance of <i>R</i>_s = 17.92, achieving a Figure of Merit (FoM) of 0.0077. The bending tests further demonstrate that the QD-LEDs with this electrode retain their luminance up to 6325 cd m^–2 after undergoing 500 bending cycles at a bending radius of 5 mm. Furthermore, this study introduces not only a highly mechanically robust device, but also an integration method for textile systems by employing an innovative lateral driving display system architecture enabling the precise addressing of individual QD-LEDs in a textile display.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 12","pages":"5961–5970 5961–5970"},"PeriodicalIF":5.3,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsanm.5c00068","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143714124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smart Textile Display with Addressable Quantum Dot Light-Emitting Diode Based on Durable Ultrathin Metal Electrode.","authors":"Jiajie Yang, Jeong-Wan Jo, Yoonwoo Kim, Sung-Min Jung, Sanghyo Lee, Jong Min Kim","doi":"10.1021/acsanm.5c00068","DOIUrl":"10.1021/acsanm.5c00068","url":null,"abstract":"<p><p>We report a fully addressable smart textile display using quantum dot light-emitting diodes (QD-LEDs) featuring a highly durable electrode. The key innovation lies in the development of an ultrathin oxide/metal hybrid structure for the durable electrode, which achieves mechanical bending durability surpassing the indium tin oxide (ITO) electrode. The optimized electrode, composed of MoO₃ and Au, exhibits a transmittance of <i>T</i> ₅₅₀ = 81%, while maintaining a sheet resistance of <i>R</i> _s = 17.92, achieving a Figure of Merit (FoM) of 0.0077. The bending tests further demonstrate that the QD-LEDs with this electrode retain their luminance up to 6325 cd m^-2 after undergoing 500 bending cycles at a bending radius of 5 mm. Furthermore, this study introduces not only a highly mechanically robust device, but also an integration method for textile systems by employing an innovative lateral driving display system architecture enabling the precise addressing of individual QD-LEDs in a textile display.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 12","pages":"5961-5970"},"PeriodicalIF":5.3,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11959519/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143770693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In-Flight Observation and Surface Oxidation Modification of Tin Oxide Nanoparticles for Gas Sensing Applications.","authors":"Calle Preger, Linnéa Jönsson, Pau Ternero, Mehran Sedrpooshan, Marie Bermeo, Antti Kivimäki, Noelle Walsh, Maria E Messing, Axel Christian Eriksson, Jenny Rissler","doi":"10.1021/acsanm.5c00144","DOIUrl":"10.1021/acsanm.5c00144","url":null,"abstract":"<p><p>Metal oxide nanoparticles are essential in various applications, and the synthesis through gas-phase generation methods offers a rapid and reliable pathway for nanoparticle production. Yet achieving precise control over their formation remains challenging due to the complex nature of oxidation processes. While bulk oxidation states can be assessed via off-line measurements, the dynamic nature of surface oxidation is more difficult to monitor and optimize in real time. Here, we investigate the surface oxidation state of unsupported tin oxide nanoparticles using an aerosol sample-delivery system and in-flight X-ray photoelectron spectroscopy. This powerful method allows the continuous monitoring of the surface oxidation of the gas-phase generated nanoparticles in real time, avoiding uncertainties associated with postcollection alterations. Tin oxide nanoparticles are widely used in gas sensing and catalytic applications, where the surface oxide layer plays a crucial role in determining their performance. Our findings demonstrate how the surface oxidation state of the free-flying particles can be controlled by adjusting the carrier gas composition, in-flight heating temperature, and particle composition. Specifically, the surface oxides of tin are partially reduced when heated in a slightly reducing atmosphere, and the reduction is further enhanced by forming mixed tin-gold nanoparticles. While previous studies on metal oxide nanoparticles have focused predominantly on bulk properties or off-line analysis, this study employs real-time in-flight X-ray photoelectron spectroscopy to investigate details of the surface oxidation state. Understanding the surface oxidation of metal oxide nanoparticles is essential to optimize processes, such as in-flight coating or subsequent deposition into a protective environment. This approach enables the exploration of direct correlations between generation conditions and surface properties, providing valuable insights into optimizing gas-phase nanoparticle synthesis.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 12","pages":"6004-6013"},"PeriodicalIF":5.3,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11959520/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143770691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sustainable 3D Nanofiber Aerogel Monoliths from Short Jute Fiber for Thermal Insulation","authors":"Abu Yousuf Mohammad Anwarul Azim,&nbsp;Jianhua Ren,&nbsp;Isao Tabata and Kazumasa Hirogaki*,&nbsp;","doi":"10.1021/acsanm.5c0021710.1021/acsanm.5c00217","DOIUrl":"https://doi.org/10.1021/acsanm.5c00217https://doi.org/10.1021/acsanm.5c00217","url":null,"abstract":"<p >Natural fiber-based sustainable aerogels have huge potential applications due to their low density, porous nanostructure, and high specific surface area. Here, the novel nanoporous three-dimensional (3D) jute nanofiber aerogel monoliths were successfully developed by a sol–gel–aerogel process, which were then analyzed and their potential application as thermal insulators evaluated. Acetone, an antisolvent, is used to regenerate short jute fiber (<i>Corchorus capsularis</i>) dissolved in dimethyl sulfoxide (DMSO)/tetrabutylammonium fluoride hydrate (TBAF) mixed solvents into wet gels. Wet gels are then dried by supercritical carbon dioxide (scCO₂) to obtain the jute nanofiber aerogels (JNAs). The gelation process, porosity, pore size, micromorphology, mechanical property, Brunauer–Emmett–Teller (BET) analysis (nitrogen gas adsorption), and thermal properties are carefully characterized. The findings indicate that the percentage of the fiber content in sols is related to the density of the nanofibrous structure, specific surface area, nanopore size, compressive modulus, and other properties as well. The aerogels have a very high specific surface area (172–1253 m² g^–1), very low density (0.0074–0.0490 g cm^–3), high compressive modulus (0.07–4.52 MPa), and high porosity (96.62–99.49%). Furthermore, attenuated total reflectance-Fourier transform infrared spectroscopy is used to confirm the possible existence of strong hydrogen bonds between the cellulose monomers. These nanostructures are an important factor to achieve the thermal insulation properties of JNAs, which make them suitable for a thermal insulator beneath metal roofing application.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 12","pages":"6073–6084 6073–6084"},"PeriodicalIF":5.3,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143714099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to “Lipoic Acid Capped Ag2S Quantum Dots for Mitochondria-Targeted NIR-II Fluorescence/Photoacoustic Imaging and Chemotherapy/Photothermal Treatment of Tumors”","authors":"Yang Xuan,&nbsp;Zhou Su,&nbsp;Meng Guan,&nbsp;Yinan Zhao,&nbsp;Wenliang Zhang,&nbsp;Yating Gao,&nbsp;Xinyu Bian,&nbsp;Mingfan Zhang,&nbsp;Donghui Zhao* and Shubiao Zhang*,&nbsp;","doi":"10.1021/acsanm.5c0126710.1021/acsanm.5c01267","DOIUrl":"https://doi.org/10.1021/acsanm.5c01267https://doi.org/10.1021/acsanm.5c01267","url":null,"abstract":"","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 12","pages":"6266 6266"},"PeriodicalIF":5.3,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143714068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Step toward Superior Nanoscale Biosensing: Investigation of Trace Cytochrome c Using TiO2 SERS Substrates and Phosphonium-Based Fluorine-Free Ionic Liquid “Linkers”","authors":"Yiqun Su,&nbsp;Mian Gong,&nbsp;Yipeng Liu,&nbsp;Faiz Ullah Shah,&nbsp;Aatto Laaksonen and Rong An*,&nbsp;","doi":"10.1021/acsanm.5c0088910.1021/acsanm.5c00889","DOIUrl":"https://doi.org/10.1021/acsanm.5c00889https://doi.org/10.1021/acsanm.5c00889","url":null,"abstract":"<p >Titanium dioxide (TiO₂) nanostructures exhibit exceptional flexibility for integration into surface-enhanced Raman spectroscopy (SERS) sensing platforms enabling nanoscale trace detection of biomolecules with high sensitivity. However, fabricating TiO₂ nanomaterials for large-scale SERS applications remains challenging due to the high cost and complexity of synthesis methods. In this study, we demonstrate a cost-effective and scalable approach using commercial TiO₂ P25 nanoparticles as the SERS substrates, functionalized with a phosphonium-based fluorine-free ionic liquid (IL) comprising the trihexyl(tetradecyl)phosphonium cation ([P_6,6,6,14]⁺) with four long alkyl chains and the 2–2-(2-methoxyethoxy)ethoxy anion ([MEEA]⁻). This IL serves as a nanoscale “linker”, effectively bridging Cytochrome c (Cyt c) molecules with TiO₂ nanoparticles, significantly enhancing the Cyt c–TiO₂ interactions and SERS signal intensity. The optimized system achieves remarkable sensitivity, enabling the detection of Cyt c concentrations as low as 5 × 10^–4 M, with an enhancement factor increased by 1 order of magnitude compared to the control system. This work stresses the importance of nanoscale interactions and offers an alternative straightforward strategy for trace protein detection using commercially available TiO₂ P25 nanoparticles, thus circumventing the need for complex nanomaterial fabrication methods.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 12","pages":"6234–6241 6234–6241"},"PeriodicalIF":5.3,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143714058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nitrogen-Doped Graphene Quantum Dots (N-GQDs): A Promising Material for the Development of Electrochemical Immunosensors","authors":"Gustavo Martins,&nbsp;Ana Laura S. Galvan,&nbsp;Marcia G. P. Valenga,&nbsp;Thomas Antonio Cardozo Martins,&nbsp;Márcio F. Bergamini* and Luiz Humberto Marcolino-Junior*,&nbsp;","doi":"10.1021/acsanm.4c0656810.1021/acsanm.4c06568","DOIUrl":"https://doi.org/10.1021/acsanm.4c06568https://doi.org/10.1021/acsanm.4c06568","url":null,"abstract":"<p >Electrochemical immunosensors have emerged as alternatives for the early diagnosis of diseases. The performance of such devices can be significantly improved by incorporating quantum dot materials, which enhance electron transfer and biomolecule immobilization. In this study, nitrogen-doped graphene quantum dots (N-GQDs) were synthesized, characterized, and applied to the assembly of label-free electrochemical immunosensors for the detection of antibodies against the receptor-binding domain (RBD) of the SARS-CoV-2 virus. The N-GQDs consisted of spherical-shaped particles, with a relatively narrow size distribution between 12.1 and 16.4 nm. Material characterization also showed the presence of oxygen groups as well as the presence of nitrogen heteroatoms. The N-GQDs were electrodeposited on screen-printed carbon electrodes, and the recognition site (RBD) of the SARS-CoV-2 S-protein was immobilized on them. Devices were applied to the determination of antibodies against SARS-CoV-2 RBD protein (Ab-RBD), and enabled analyte determination for the concentration level as low as 500 ng mL^–1 in the presence of a commercial serum matrix and a linear detection range up to 4.0 μg mL^–1. Additionally, the immunosensor was selective toward the presence of antibodies against the SARS-CoV-2 nucleocapsid protein (Ab-N) and enabled the differentiation of the response from negative and positive serum samples. The assembled device provided a stable analytical response for Ab-RBD detection when stored for up to 28 days. Therefore, the N-GQD material was obtained, and its performance as a modifying material for immunosensor assembly was successfully demonstrated, representing an alternative screening method to be employed in endemic and pandemic scenarios and to verify the efficiency of vaccines and humoral immunity.</p>","PeriodicalId":6,"journal":{"name":"ACS Applied Nano Materials","volume":"8 12","pages":"5908–5918 5908–5918"},"PeriodicalIF":5.3,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsanm.4c06568","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143713971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}