Acta dermato-venereologica最新文献_第4页

JAK Inhibitors in Down Syndrome: Alopecia Areata Resolution and Vitiligo Improvement with Baricitinib. 唐氏综合征的JAK抑制剂：Baricitinib治疗斑秃和白癜风。

IF 3.7 4区医学

Acta dermato-venereologica Pub Date : 2025-09-10 DOI: 10.2340/actadv.v105.44081

Federica Li Pomi, Mario Vaccaro, Marta Vitale, Roberta Alaimo, Francesco Borgia

引用次数: 0

Baricitinib 2 mg/day as a Cost-conscious Entry Point to Systemic Therapy in Moderate-to-severe Atopic Dermatitis: Real-world Data from a Japanese Clinic. Baricitinib 2mg /天作为中重度特应性皮炎系统治疗的成本意识切入点：来自日本诊所的真实世界数据

IF 3.7 4区医学

Acta dermato-venereologica Pub Date : 2025-09-10 DOI: 10.2340/actadv.v105.43616

Masato Mizuashi

引用次数: 0

Solitary Facial Nodule in a Young Female Patient: A Quiz. 一位年轻女性患者的面部孤立结节：一个小测验。

IF 3.7 4区医学

Acta dermato-venereologica Pub Date : 2025-09-04 DOI: 10.2340/actadv.v105.44549

Diogo De Sousa, Claúdia Brazão, Pedro Vasconcelos, Paulo Filipe

引用次数: 0

Intralesional Corticosteroid Versus Cryotherapy for Alopecia Areata: A Systematic Review and Meta-analysis. 斑块内皮质类固醇与冷冻治疗斑秃：系统回顾和荟萃分析。

IF 3.7 4区医学

Acta dermato-venereologica Pub Date : 2025-09-04 DOI: 10.2340/actadv.v105.44435

Yu-Cheng Liu, Kai-Wen Chuang, Hua-Ching Chang

引用次数: 0

Exploring the Risk Factors of Rosacea Exacerbation Associated with COVID-19 Infection or Vaccination: A Cross-sectional Study. 探讨与COVID-19感染或疫苗接种相关的酒渣鼻加重的危险因素：一项横断面研究

IF 3.7 4区医学

Acta dermato-venereologica Pub Date : 2025-09-04 DOI: 10.2340/actadv.v105.43615

Xidie Yin, Yiting Zhao, Liyuan Zhou, Xiaojing Liu, Yu Yan, Zhi Cao, Shu Zhan Shen, Qihang Chang, Yajing Cao, Xiuli Wang, Peiru Wang

{"title":"Exploring the Risk Factors of Rosacea Exacerbation Associated with COVID-19 Infection or Vaccination: A Cross-sectional Study.","authors":"Xidie Yin, Yiting Zhao, Liyuan Zhou, Xiaojing Liu, Yu Yan, Zhi Cao, Shu Zhan Shen, Qihang Chang, Yajing Cao, Xiuli Wang, Peiru Wang","doi":"10.2340/actadv.v105.43615","DOIUrl":"10.2340/actadv.v105.43615","url":null,"abstract":"COVID-19 can affect the skin, with rosacea flare-ups reported after infection or vaccination. This study compared rosacea patients with and without post-COVID-19 exacerbation to identify contributing factors. A customized electronic questionnaire was administered to rosacea patients, gathering COVID-19 infection/vaccination status, demographics, and rosacea features. Participants were classified by post-COVID-19 rosacea exacerbation vs none. Multivariable logistic regression identified risk factors. Finally, a total of 104 patients were analysed; 15.4% experienced rosacea exacerbation after COVID-19 vaccination and 28.8% after infection. Comorbidities such as metabolic diseases or allergic diseases were associated with a higher risk of rosacea exacerbation after vaccination or infection (OR = 11.083, 95% CI: 1.136-108.135). Burning and stinging symptoms predicted higher exacerbation risk after vaccination (OR = 8.978, 95% CI 1.968-40.969). Papulopustular rosacea was associated with lower risk (OR = 0.276, 95% CI: 0.066-1.160). Higher body mass index (BMI) was associated with lower exacerbation risk after vaccination (OR = 0.646, 95% CI 0.450-0.928) and infection (OR = 0.731, 95% CI: 0.572-0.933). Frequent rosacea episodes increased exacerbation risk after infection (OR = 8.288, 95% CI: 2.044-33.608). In conclusion, lower BMI was associated with higher risk of rosacea exacerbation after COVID-19 vaccination or infection. Patients with burning and stinging symptoms or a non-papulopustular subtype were more likely to experience exacerbation after vaccination.","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"105 ","pages":"adv43615"},"PeriodicalIF":3.7,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12427583/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144999435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New-onset Autoimmune Diseases in Patients with Prurigo Nodularis: A Global-federated Retrospective Cohort Study. 结节性痒疹患者新发自身免疫性疾病：一项全球联合回顾性队列研究

IF 3.7 4区医学

Acta dermato-venereologica Pub Date : 2025-09-04 DOI: 10.2340/actadv.v105.43515

Hui-Chin Chang, Chia-Chi Chang, Yen-Ju Chu, Wei-Ting Hsu, Yun-Feng Li, Yi-Sheng Jhang, Yu-Jung Su, Shiu-Jau Chen, Torsten Zuberbier, Shuo-Yan Gau

{"title":"New-onset Autoimmune Diseases in Patients with Prurigo Nodularis: A Global-federated Retrospective Cohort Study.","authors":"Hui-Chin Chang, Chia-Chi Chang, Yen-Ju Chu, Wei-Ting Hsu, Yun-Feng Li, Yi-Sheng Jhang, Yu-Jung Su, Shiu-Jau Chen, Torsten Zuberbier, Shuo-Yan Gau","doi":"10.2340/actadv.v105.43515","DOIUrl":"10.2340/actadv.v105.43515","url":null,"abstract":"Prurigo nodularis (PN) has been associated with autoimmune diseases, though longitudinal data are limited. This study investigates the risk of autoimmune disease development in PN patients using a global electronic health record database. This retrospective cohort study analysed data from the Global Collaborative Network within the TriNetX research network. Adults (≥ 18 years) with PN were compared with propensity score-matched controls without PN. Matching considered age, sex, comorbidities, race, and socioeconomic status. Patients with prior autoimmune diseases or cancers were excluded. Incident autoimmune diseases, including systemic lupus erythematosus (SLE), Sjögren's syndrome, psoriasis, ankylosing spondylitis (AS), rheumatoid arthritis (RA), Crohn's disease (CD), and ulcerative colitis (UC), were evaluated using hazard ratios (HR). Among 17,963 PN patients and the same amount of matched pairs, PN patients had higher risks for SLE (HR: 2.16, 95% CI: 1.44-3.24), Sjögren's syndrome (HR: 1.86, 95% CI: 1.33-2.59), and psoriasis (HR: 3.20, 95% CI: 2.58-3.97). Stratified analysis revealed that female PN patients had higher risks for SLE and Sjögren's syndrome, while psoriasis risk was elevated in both sexes, especially in males. Risks for AS, RA, CD, and UC were not significant. Sensitivity analyses validated these findings. In conclusion, PN is linked to increased risks for SLE, Sjögren's syndrome, and psoriasis, highlighting the need for proactive screening and management of autoimmune diseases in PN patients.","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"105 ","pages":"adv43515"},"PeriodicalIF":3.7,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12427582/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144999420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Retrospective Analysis of Itch Intensity and Comorbidities in Lichen Simplex Chronicus. 慢性单纯地衣瘙痒强度及合并症的回顾性分析。

IF 3.7 4区医学

Acta dermato-venereologica Pub Date : 2025-09-04 DOI: 10.2340/actadv.v105.43776

Kayla D Mashoudy, Joselyn Ye-Tay, Sarah Kim, Nicole Khalil, Gil Yosipovitch

{"title":"A Retrospective Analysis of Itch Intensity and Comorbidities in Lichen Simplex Chronicus.","authors":"Kayla D Mashoudy, Joselyn Ye-Tay, Sarah Kim, Nicole Khalil, Gil Yosipovitch","doi":"10.2340/actadv.v105.43776","DOIUrl":"10.2340/actadv.v105.43776","url":null,"abstract":"Lichen simplex chronicus is a chronic pruritic skin condition that significantly impacts quality of life. This retrospective study analysed 125 patients with clinically confirmed lichen simplex chronicus seen at a tertiary academic centre to characterize itch severity, anatomical distribution, and associated comorbidities. Itch intensity was assessed using the Numerical Rating Scale (NRS), and clinical data were stratified by demographics and disease extent. Most patients (75%) reported moderate-to-severe itch (NRS 4-10), with nearly 90% experiencing daily pruritus and half reporting both daytime and nocturnal symptoms. The limbs were the most commonly affected sites. Comorbid conditions were frequent, including generalized anxiety disorder (50% vs ~3% in the US adult population), major depressive disorder (44% vs ~8%), hypertension (61% vs ~45%), and type 2 diabetes (30% vs ~11%). Patients with multiple-lesion lichen simplex chronicus had significantly higher itch severity (mean NRS 7.81 vs 7.08, p = 0.001) and were more likely to be female (81% vs 46%, p = 0.002) compared with those with localized disease. These findings highlight the high symptom burden and frequent co-occurrence of psychiatric and metabolic comorbidities in lichen simplex chronicus. Thus, early identification and management of psychiatric, neurological, and metabolic conditions may improve outcomes for patients with lichen simplex chronicus.","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"105 ","pages":"adv43776"},"PeriodicalIF":3.7,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12427579/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144999461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Paradoxical Associations Between Sun-Protective Behaviours and Mortality: Evidence From a Nationally Representative Cohort. 防晒行为与死亡率之间的矛盾关联：来自全国代表性队列的证据。

IF 3.7 4区医学

Acta dermato-venereologica Pub Date : 2025-09-02 DOI: 10.2340/actadv.v105.44507

Xiaofeng Liang, Zhishen Peng, Peixian Chen, Ying Deng, Jinglin Gao, Yongyi Liang, Yujing Niu

引用次数: 0

Successful Treatment of Subcorneal Pustular Dermatosis with Abrocitinib. 阿布替尼成功治疗角膜下脓疱性皮肤病。

IF 3.7 4区医学

Acta dermato-venereologica Pub Date : 2025-09-01 DOI: 10.2340/actadv.v105.44512

Zirui Chen, Jiahui Zhao, Hang Li

引用次数: 0

Giant Plaques on the Back with Gyrus-like Alteration: A Quiz. 巨大的斑块与脑回样的改变：一个测验。

IF 3.7 4区医学

Acta dermato-venereologica Pub Date : 2025-09-01 DOI: 10.2340/actadv.v105.44562

Mingxuan Ma, Shuli Gu, Jiaao Fang, Guangwen Yin

引用次数: 0