Acta dermato-venereologica最新文献_第4页

European S2k Guideline on Chronic Pruritus 欧洲S2k慢性瘙痒指南

IF 3.7 4区医学

Acta dermato-venereologica Pub Date : 2025-08-22 DOI: 10.2340/actadv.v105.44220

Elke Weisshaar, Simon Müller, Jacek C Szepietowski, Florence Dalgard, Simone Garcovich, Jörg Kupfer, Ana Gimenez-Arnau, Julien Lambert, Thomas Mettang, Laurent Misery, Ekin Savk, Erwin Tschachler, Joanna Wallengren, Sonja Ständer

引用次数: 0

Obesity: A Modulator in Acne Management. 肥胖：痤疮管理的调节剂。

IF 3.7 4区医学

Acta dermato-venereologica Pub Date : 2025-08-21 DOI: 10.2340/actadv.v105.43945

Jean-Paul Claudel, Fabienne Ballanger, Nicole Auffret, Marie-Thérèse Leccia, Brigitte Dréno

{"title":"Obesity: A Modulator in Acne Management.","authors":"Jean-Paul Claudel, Fabienne Ballanger, Nicole Auffret, Marie-Thérèse Leccia, Brigitte Dréno","doi":"10.2340/actadv.v105.43945","DOIUrl":"https://doi.org/10.2340/actadv.v105.43945","url":null,"abstract":"Acne vulgaris is an inflammatory and multifactorial skin disease involving the sebaceous gland and the skin microbiome. Different exposome factors, including hormonal and family factors, have been suggested to influence acne. Obesity is an increasingly observed condition worldwide, and is considered as a public health problem by the World Health Organization. Recently, a high body mass index has been identified as an acne severity risk factor in adolescents. A group of 5 dermatologists from different institutions and private practices from France involved in the research and clinical fields of acne -analysed recent literature on \"obesity and acne\" focusing on epidemiology, the pathogenesis of acne and obesity, as well as the management of acne in obese patients. The authors selected, prior to their discussion in November and December 2024 and again in March 2025, and discussed 52 articles concerning acne and obesity published since 2000 and available from the PubMed database. The authors agreed that, considering these common metabolic features, managing both acne and obesity in parallel and helping patients through a global approach including dermatological, endocrinal, psychological and nutrition, as well as lifestyle support is mandatory, and may allow for the improvement of both acne and obesity. Moreover, in order to allow dermatologists to manage acne in obese patients in the most efficient way, the authors developed and propose a decision tree. The authors consider that acne in obese patients is not a fatality, and taking care of acne should not be considered an isolated task in this specific patient population.","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"105 ","pages":"adv43945"},"PeriodicalIF":3.7,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12382383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A 9-month-old Child with Diffuse Cutaneous Bullous Erythema: A Quiz. 一个9个月大的儿童弥漫性皮肤大疱性红斑：一个小测验。

IF 3.7 4区医学

Acta dermato-venereologica Pub Date : 2025-08-21 DOI: 10.2340/actadv.v105.43939

Shengyuan Hua, Jing Chen, Qiufang Qian, Jia Zhang

引用次数: 0

High Prevalence of Lash Collarettes in Patients with Atopic Dermatitis Treated with Dupilumab. 杜匹单抗治疗特应性皮炎患者中睫毛脱落的高患病率

IF 3.7 4区医学

Acta dermato-venereologica Pub Date : 2025-08-18 DOI: 10.2340/actadv.v105.43322

Ilaria Trave, Ilaria Salvi, Rei Canameri, Carlo Alberto Cutolo, Chiara Bonzano, Matteo Baldi, Carolina Bologna, Gabriele Drago, Giorgio Battaglia, Aurora Parodi, Michele Iester, Emanuele Cozzani

引用次数: 0

PAPASH Syndrome with a Pathogenic PSTPIP1 p.(Ala230Thr) Variant: A Case Report of Therapeutic Complexity. PAPASH综合征伴致病性PSTPIP1 p.（Ala230Thr）变异：一例治疗复杂性报告

IF 3.7 4区医学

Acta dermato-venereologica Pub Date : 2025-08-18 DOI: 10.2340/actadv.v105.43622

Meri Tikka, Tiina Ilves

引用次数: 0

In Vitro Evidence Demonstrating the Nondepleting Mechanism of Action of Amlitelimab, an OX40 Ligand Monoclonal Antibody. OX40配体单克隆抗体Amlitelimab非耗竭作用机制的体外证据

IF 3.7 4区医学

Acta dermato-venereologica Pub Date : 2025-08-18 DOI: 10.2340/actadv.v105.43608

James G Krueger, Brian S Kim, Stephan Weidinger, Yoko Kataoka, John T O'Malley, Karl Yen, Cassie Van Krinks, Jose Vela

引用次数: 0

Adverse Events and Immune Response in Psoriasis Patients Receiving Interleukin-17 Inhibitors. 银屑病患者接受白介素-17抑制剂的不良事件和免疫反应。

IF 3.7 4区医学

Acta dermato-venereologica Pub Date : 2025-08-18 DOI: 10.2340/actadv.v105.43685

Christopher Willy Schwarz, Charlotte Näslund-Koch, Claus Zachariae, Jakob Benedict Seidelin, Susanne Dam Nielsen, Sisse Rye Ostrowski, Karen Marie Thyssen Astvad, Inger Brock, Lars Iversen, Mads Kirchheiner Rasmussen, Nikolai Loft, Lone Skov

{"title":"Adverse Events and Immune Response in Psoriasis Patients Receiving Interleukin-17 Inhibitors.","authors":"Christopher Willy Schwarz, Charlotte Näslund-Koch, Claus Zachariae, Jakob Benedict Seidelin, Susanne Dam Nielsen, Sisse Rye Ostrowski, Karen Marie Thyssen Astvad, Inger Brock, Lars Iversen, Mads Kirchheiner Rasmussen, Nikolai Loft, Lone Skov","doi":"10.2340/actadv.v105.43685","DOIUrl":"10.2340/actadv.v105.43685","url":null,"abstract":"Interleukin-17 inhibitors are effective in psoriasis; however, they are associated with an increased risk of infections, particularly oral candidiasis, and new-onset/flares of inflammatory bowel disease. This study aimed to identify predictive markers for these adverse events and to describe the functional immune response in patients treated with interleukin-17 inhibitors using a whole-blood stimulation system (TruCulture®). Patients with psoriasis initiating an interleukin-17 inhibitor (n = 36) or adalimumab (n = 24) were enrolled. Patients attended visits at baseline, week 12, and week 52, during which skin and mucosal swabs, and faecal and blood samples were collected. Baseline oral Candida albicans colonization with no clinical symptoms was associated with an increased risk of oral candidiasis during the first year of interleukin-17 inhibitor therapy, with no cases of oral candidiasis observed in the adalimumab group. Gut inflammation, measured by faecal calprotectin, remained stable in both the adalimumab and interleukin-17 inhibitor group. Colonization with Staphylococcus aureus did not change during treatment. It was found that interleukin-17 inhibitors induced an anti-inflammatory state and potentially more active toll-like receptor 3-mediated antiviral responses compared with adalimumab. In conclusion, screening for oral Candida albicans colonization prior to initiation of interleukin-17 inhibitor therapy may be a useful strategy for risk stratification and early intervention.","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"105 ","pages":"adv43685"},"PeriodicalIF":3.7,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12376385/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144870726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Hidden Socioeconomic Toll of Severe Hidradenitis Suppurativa. 严重化脓性汗腺炎隐藏的社会经济代价。

IF 3.7 4区医学

Acta dermato-venereologica Pub Date : 2025-08-18 DOI: 10.2340/actadv.v105.44495

Florian Regensberger, Fiona André, Sarah Maier, Christian Posch, Matthias Schmuth

引用次数: 0

Evaluating Melanoma Risk in Adult Mastocytosis: Potential Impact of Detection Bias - A Registry-based Study (Sweden). 评估成人肥大细胞增多症的黑色素瘤风险：检测偏差的潜在影响-一项基于登记的研究（瑞典）。

IF 3.7 4区医学

Acta dermato-venereologica Pub Date : 2025-08-18 DOI: 10.2340/actadv.v105.43052

Anna Bergström, Hans Hägglund, Anders Berglund, Gunnar Nilsson, Mats Lambe

{"title":"Evaluating Melanoma Risk in Adult Mastocytosis: Potential Impact of Detection Bias - A Registry-based Study (Sweden).","authors":"Anna Bergström, Hans Hägglund, Anders Berglund, Gunnar Nilsson, Mats Lambe","doi":"10.2340/actadv.v105.43052","DOIUrl":"10.2340/actadv.v105.43052","url":null,"abstract":"There is some evidence that mastocytosis patients are at increased risk of skin cancer. This study aimed to assess the risk of malignant melanoma (MM), melanoma in situ (Mis), and basal cell carcinoma (BCC). A dataset was generated by individual-level record linkages between Swedish population registers including the National Patient Register (NPR), the Swedish Cancer Register (SCR), and the Population Register (PR). Adult patients with a mastocytosis diagnosis between 2001 and 2018 were identified in the SCR and NPR. For each case, 5 mastocytosis-free comparators matched on age, sex, and county of residence were randomly chosen from the PR. Records of skin cancer were identified in the SCR and NPR. In total, the study encompassed 2,040 mastocytosis patients of whom 63 had a record of MM/Mis and 168 a record of BCC. Compared with comparators, the risk of MM/Mis was more than twofold higher (OR 2.39, 95% CI 1.8-3.2). Risk estimates for BCC were also elevated (OR 1.77, 95% CI 1.49-2.14). When assessing the timing of skin cancers, a substantial portion were diagnosed near index date. Taken together, in the present study these findings of increased risk of MM/Mis and BCC in mastocytosis patients may reflect an influence of detection bias.","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"105 ","pages":"adv43052"},"PeriodicalIF":3.7,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12371744/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144870727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Global, Regional, and National Burden of Alopecia Areata and its Associated Comorbidities, 1990-2021, and Projections to 2050: An Analysis of the Global Burden of Disease Study 2021. 全球、地区和国家斑秃及其相关合并症的负担，1990-2021年，以及到2050年的预测：2021年全球疾病负担研究分析

IF 3.7 4区医学

Acta dermato-venereologica Pub Date : 2025-08-18 DOI: 10.2340/actadv.v105.43367

Dan Wang, Peizhi Deng, Shengbo Yang, Yangfan Xu, Jianyun Lu

{"title":"Global, Regional, and National Burden of Alopecia Areata and its Associated Comorbidities, 1990-2021, and Projections to 2050: An Analysis of the Global Burden of Disease Study 2021.","authors":"Dan Wang, Peizhi Deng, Shengbo Yang, Yangfan Xu, Jianyun Lu","doi":"10.2340/actadv.v105.43367","DOIUrl":"10.2340/actadv.v105.43367","url":null,"abstract":"There are no updated epidemiological data on alopecia areata up to 2021. The objective of this study was to emphasize the urgency of addressing the evolving public health challenges of alopecia areata. The annual point prevalence, incidence, and years lived with disability of alopecia areata from 204 countries and regions from 1990-2021 were extracted. Subgroup analyses based on gender, age, global, national, regional, sociodemographic index, and World Bank income were conducted. From 1990-2021, age-standardized prevalence, incidence, and years lived with disability of alopecia areata globally show a decreasing trend, with females dominating. There was a reduction in the disease burden in high sociodemographic index regions, but alopecia areata in general did not reflect a concentration in certain regions and was more equally distributed. Decomposition analysis revealed that population growth was the major contributor to the burden of alopecia areata, followed by population ageing. Patients with alopecia areata before the age of 14 were associated with anxiety disorders and other psychological disorders, but patients after the age of 14 were not associated with the onset of these disorders. Also, atopic dermatitis has been associated with alopecia areata. The epidemiological differences in psychological disorders between children and adolescents/adults with alopecia areata further demonstrate the importance of differentiated recognition at different ages.","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"105 ","pages":"adv43367"},"PeriodicalIF":3.7,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12376388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144870728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0