Acta dermato-venereologica最新文献

{"title":"Molluscum Contagiosum, Warts and Condylomas during JAK Inhibitor Therapy for Atopic Dermatitis: a Retrospective Series of 17 Cases.","authors":"Giuseppe Russo, Emmanuel Mahé, Florence Tetart, Audrey Loretan, Audrey Nosbaum, Marie Tauber, Nadia Raison-Peyron, Estelle Burle, Angèle Soria, Emilie Brenaut, Anne Saussine, Thibault Mahévas, Jean-David Bouaziz, Emmanuel Laffitte, Marie Jachiet","doi":"10.2340/actadv.v106.adv-2026-0779","DOIUrl":"https://doi.org/10.2340/actadv.v106.adv-2026-0779","url":null,"abstract":"","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"106 ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149163483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"OX40/OX40L Inhibitors in Atopic Dermatitis: Current Evidence on Short-term Safety.","authors":"Kian Karimian, Daniel Isufi, Mikkel Bak Jensen, Raj Chovatiya, Christopher G Bunick, Tiago Torres, Jakob Ferløv Baselius Schwensen, Nikolai Loft","doi":"10.2340/actadv.v106.adv-2026-0665","DOIUrl":"10.2340/actadv.v106.adv-2026-0665","url":null,"abstract":"","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"106 ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13656841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149163799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Invisible Challenges of a Visible Disease: A Qualitative Study on Disease-related Impairment, Participation Barriers and Care Experiences in Adults with Ichthyosis.","authors":"Jana Stucke, Alina Wacker, Kira Suessmuth, Vinzenz Oji, Sabine Steinke","doi":"10.2340/actadv.v106.adv-2025-0166","DOIUrl":"10.2340/actadv.v106.adv-2025-0166","url":null,"abstract":"<p><p>Ichthyoses are rare genodermatoses characterized by scaling, hyperkeratosis, and barrier dysfunction, often accompanied by hypohidrosis and pruritus. Beyond visible symptoms, ichthyosis imposes substantial psychosocial, financial, and time-related challenges. This qualitative study explored patient-perceived impairments, disability, and experiences with medical and social care. Semi-structured interviews were conducted with 18 adults (13 women, 5 men; aged 18-67 years) with various ichthyosis subtypes, recruited from two specialized dermatology clinics in Germany and the patient organization Ichthyosis e.V. Reflexive thematic analysis showed that participants' daily lives were influenced not only by symptoms and time-consuming care routines but also by social and structural factors limiting participation in various life domains. Participants reported inequalities in education and employment, rejection during job seeking and at work. This can lead to social anxiety, depression, and negative self-image. Psychological strain also arises from limited treatment options and financial strain. Perceptions of disability vary, though many seek formal recognition. The impact of ichthyosis is often underestimated by healthcare professionals, complicating access to social and medical support. Dermatologists should recognize the crucial role of their diagnosis and documentation and carefully guide patients through the healthcare system to ensure appropriate socio-medical support.</p>","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"106 ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13643892/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149126303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Haemophagocytic Lymphohistiocytosis Following Severe Erysipelas with EBV Reactivation.","authors":"Thilo Gambichler, Josefine Brune, Laura Susok","doi":"10.2340/actadv.v106.adv-2026-0822","DOIUrl":"10.2340/actadv.v106.adv-2026-0822","url":null,"abstract":"","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"106 ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13643893/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149126317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and Safety of Delgocitinib and Its Impact on Patient's Perspective for Moderate-to-severe Chronic Hand Eczema in Adults: A 16-week Real-world Prospective Multicentre Study.","authors":"Elena Pezzolo, Raul Armando Luyo Saboya, Michela Ortoncelli, Simone Ribero, Federica Gelato, Marco Galluzzo, Marina Talamonti, Edoardo Mortato, Antonio Costanzo, Luigi Gargiulo, Alessandra Narcisi, Matteo Bianco, Carlotta Gurioli, Gionathan Orioni, Camilla Loi, Niccolò Gori, Ketty Peris, Elena Ippoliti, Giampiero Girolomoni, Martina Maurelli, Maria Esposito, Sara Triolo, Caterina Foti, Giorgia Sbarra, Ersilia Tolino, Nevena Skroza, Andrea Carugno, Nicola Zerbinati, Anna Balato, Eugenia Veronica Di Brizzi, Martina Burlando, Vito Di Lernia, Pietro Morrone, Emiliano Antiga, Maria Concetta Fargnoli, Filomena Russo, Francesca Caroppo, Laura Fagotto, Piergiacomo Calzavara-Pinton, Stefano Bighetti, Mariateresa Rossi","doi":"10.2340/actadv.v106.adv-2026-0765","DOIUrl":"10.2340/actadv.v106.adv-2026-0765","url":null,"abstract":"<p><p>Delgocitinib is a pan-Janus kinase inhibitor approved for moderate-to-severe chronic hand eczema (CHE) in adults. However, real-world evidence remains limited. We prospectively evaluated 149 adult patients (mean age: 46.4 years; 60.4 % female) treated with delgocitinib for chronic hand eczema across 20 Italian dermatology centres between May and November 2025, with a four-month follow-up. Two-thirds of patients were non-occupationally exposed, and>80% had vesicular or atopic chronic hand eczema. At week 4, Physician Global Assessment (PGA)-chronic hand eczema 0/1 and Hand Eczema Severity Index (HECSI)-75 were achieved in 42.3% and 43.8% of patients, increasing significantly to 74.3% and 88.0% at week 16. Pruritus and pain Numerical Rating Scale (NRS) 0/1 were reported in 43.8% and 52.3% of patients at week 4, rising significantly to 74.4% and 86.5% at week 16. Hand Eczema Symptom Diary-Patient Global Impression of Severity (HESD PGI-S) 0/1 increased from 45.6% to 76.6%. Non-occupationally exposed patients showed significantly higher early response rates than occupationally exposed, with attenuation of differences by week 16. HECSI-75 responses were consistent across chronic hand eczema subtypes, particularly vesicular (94.0%) and atopic (90.0%). Treatment was well tolerated, with rare and no severe adverse events reported. These findings support delgocitinib as a rapid, effective and safe treatment option for chronic hand eczema.</p>","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"106 ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13642238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149102617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multimodal Large Language Models in Dermatologic Diagnosis: A Game Changer or a Clinical Risk?","authors":"Ümit Akpinar, Mehmet Semih Çelik, Ekrem Civaş, Yildiz Hayran, Başak Yalçın","doi":"10.2340/actadv.v106.adv-2026-0586","DOIUrl":"10.2340/actadv.v106.adv-2026-0586","url":null,"abstract":"","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"106 ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13639989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149102645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in Topical Corticosteroid Dispensing Patterns Following Specialist Consultation in Patients with Atopic Dermatitis: A Two-year Longitudinal Study.","authors":"Fatema Shahin, Anne Sofie Frølunde, Christian Vestergaard","doi":"10.2340/actadv.v106.adv-2026-0783","DOIUrl":"10.2340/actadv.v106.adv-2026-0783","url":null,"abstract":"","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"106 ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13639988/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149102571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Localized Scleroderma Is Associated with an Increased Risk of Systemic Sclerosis: A Matched Cohort Study.","authors":"Bastian Aschoff, Gabriela Riemekasten, Sören Dräger, Ralf J Ludwig, Philip Curman","doi":"10.2340/actadv.v106.adv-2026-0759","DOIUrl":"10.2340/actadv.v106.adv-2026-0759","url":null,"abstract":"","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"106 ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13639990/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149102620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lawsonella clevelandensis as a Mimic of Mycobacterial Infection Presenting as Umbilical Angiomatosis-like Lesion.","authors":"Shaoheng Wang, Jing Zhang, Yun Jin, Xiaohua Tao","doi":"10.2340/actadv.v106.adv-2026-0919","DOIUrl":"10.2340/actadv.v106.adv-2026-0919","url":null,"abstract":"","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"106 ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13640434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149102675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum: Safety and Effectiveness Profile of Dupilumab in the Treatment of Atopic Dermatitis in Special Populations.","authors":"Niccolo Gori","doi":"10.2340/actadv.v106.46962","DOIUrl":"https://doi.org/10.2340/actadv.v106.46962","url":null,"abstract":"<p><p>Corrigendum to article: https://doi.org/10.2340/actadv.v105.43523.</p>","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"106 ","pages":"adv46962"},"PeriodicalIF":3.8,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149102698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}