Acta dermato-venereologica最新文献_第3页

Birth Outcomes of Infants Born to Mothers with Alopecia Areata: A Nationwide Population-based Study in Korea. 斑秃母亲所生婴儿的出生结局：韩国一项基于全国人口的研究。

IF 3.5 4区医学

Acta dermato-venereologica Pub Date : 2025-01-08 DOI: 10.2340/actadv.v105.42248

Jung-Won Shin, Taeuk Kang, Heather Swan, Kyungho Paik, Chang-Hun Huh, Hyun Jung Kim

{"title":"Birth Outcomes of Infants Born to Mothers with Alopecia Areata: A Nationwide Population-based Study in Korea.","authors":"Jung-Won Shin, Taeuk Kang, Heather Swan, Kyungho Paik, Chang-Hun Huh, Hyun Jung Kim","doi":"10.2340/actadv.v105.42248","DOIUrl":"10.2340/actadv.v105.42248","url":null,"abstract":"Data on pregnancy outcomes in patients with alopecia areata (AA) are limited. The aim of this study is to determine the association between maternal AA and risk of adverse birth outcomes in children. A retrospective cohort study was conducted on 45,328 children born to mothers with AA and 4,703,253 controls born to mothers without AA using the Korean National Health Insurance Claims database from 2002 to 2016. Multivariate logistic regression analyses were performed to evaluate the association between maternal AA and the birth outcomes of their children. Infants born to mothers with AA exhibited a significantly higher risk of preterm birth (odds ratio [OR] 1.39, 95% CI 1.33-1.45; adjusted OR [aOR] 1.07, 95% CI 1.01-1.13), low birthweight (OR 1.36, 95% CI 1.30-1.42; aOR 1.11, 95% CI 1.05-1.17), and Caesarean section birth (OR 1.24, 95% CI 1.22-1.26; aOR 1.12, 95% CI 1.08-1.15) than controls. In addition, the risk of congenital malformations was also significantly higher in infants born to mothers with AA (OR 1.19, 95% CI 1.15-1.22; aOR 1.10, 95% CI 1.07-1.14), especially for malformations of the urinary (OR 1.33, 95% CI 1.19-1.48; aOR 1.16, 95% CI 1.04-1.29) and musculoskeletal (OR 1.19, 95% CI 1.12-1.27; aOR 1.12, 95% CI 1.05-1.19) systems, than controls. Maternal AA is associated with an increased risk of adverse birth outcomes in infants.","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"105 ","pages":"adv42248"},"PeriodicalIF":3.5,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11736662/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Yellow Nodule on the Right Nipple and Multiple Yellowish Plaques on the Face: A Quiz. 右侧乳头黄色结节和面部多个黄色斑块：一个小测验。

IF 3.5 4区医学

Acta dermato-venereologica Pub Date : 2025-01-03 DOI: 10.2340/actadv.v105.42478

Yue-Tong Qian, Jia-Wei Liu, Dong-Lai Ma

引用次数: 0

Patterns of Addiction in Chronic Skin Diseases: A Comparative Analysis of Addictions and Influencing Factors in Atopic Dermatitis and Psoriasis. 慢性皮肤病的成瘾模式：特应性皮炎和牛皮癣成瘾及其影响因素的比较分析。

IF 3.5 4区医学

Acta dermato-venereologica Pub Date : 2025-01-03 DOI: 10.2340/actadv.v105.41350

Roxana Mazilu, Stefanie Ziehfreund, Tilo Biedermann, Alexander Zink

{"title":"Patterns of Addiction in Chronic Skin Diseases: A Comparative Analysis of Addictions and Influencing Factors in Atopic Dermatitis and Psoriasis.","authors":"Roxana Mazilu, Stefanie Ziehfreund, Tilo Biedermann, Alexander Zink","doi":"10.2340/actadv.v105.41350","DOIUrl":"10.2340/actadv.v105.41350","url":null,"abstract":"Addictions seem to be more frequent in atopic dermatitis and psoriasis patients than in the general population. This cross-sectional observational study comparatively evaluated substance-related and behavioural addictions in atopic dermatitis and psoriasis patients and analysed possible addiction patterns. From October 2023 to April 2024, 100 atopic dermatitis and 104 psoriasis patients at a German university hospital completed an anonymous questionnaire, including sociodemographic and health-related parameters, along with validated assessment tools for common addictions (smoking, gambling, alcohol, drugs, food, and internet). More psoriasis patients had at least 1 addiction (50.0% vs 39.0%), were more frequent daily smokers (34.6% vs 15.0%) and reported gambling more frequently than atopic dermatitis patients. No differences emerged regarding gambling addiction. Psoriasis patients showed higher body mass index, with 1.9% addicted to food. Atopic dermatitis patients were more vulnerable to pathological internet use (9.0% vs 2.9%). Low happiness was a risk factor for smoking in atopic dermatitis and for gambling and drug consumption in psoriasis patients. Low disease severity was associated with pathological alcohol in-take in psoriasis. Younger age emerged as a ubiquitous risk factor for drug consumption. Distinct addiction patterns in atopic dermatitis and psoriasis patients, influenced by age, happiness, and disease severity, should guide the development of education and screening strategies.","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"105 ","pages":"adv41350"},"PeriodicalIF":3.5,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11711691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142918914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Facial Discoid Dermatosis, a Still Unknown Entity. 面部盘状皮肤病，一个仍然未知的实体。

IF 3.5 4区医学

Acta dermato-venereologica Pub Date : 2025-01-03 DOI: 10.2340/actadv.v105.40911

Clotilde Fera, Mélanie Chamaillard, Marie Beylot-Barry, Matthieu Levavasseur

引用次数: 0

Histopathological Diagnostic Discordance between Punch Biopsies and Final Diagnostic Excisions of Cutaneous Squamous Cell Carcinoma: Analysis of 737 Cases. 737例皮肤鳞状细胞癌穿孔活检与最终诊断切除的组织病理学诊断差异分析。

IF 3.5 4区医学

Acta dermato-venereologica Pub Date : 2025-01-03 DOI: 10.2340/actadv.v105.40727

Katherine Hopkins, Åsa Ingvar, Johan Palmgren, Valdis Thorhallsdottir, Kari Nielsen, Karim Saleh

{"title":"Histopathological Diagnostic Discordance between Punch Biopsies and Final Diagnostic Excisions of Cutaneous Squamous Cell Carcinoma: Analysis of 737 Cases.","authors":"Katherine Hopkins, Åsa Ingvar, Johan Palmgren, Valdis Thorhallsdottir, Kari Nielsen, Karim Saleh","doi":"10.2340/actadv.v105.40727","DOIUrl":"10.2340/actadv.v105.40727","url":null,"abstract":"The recommended treatment for cutaneous squamous cell carcinoma is surgical excision. An initial punch biopsy is often performed as an aid to diagnosis. A retrospective registry-based study was performed to assess histopathological concordance of punch biopsy of cutaneous squamous cell carcinoma and subsequent excision. Analysis of 737 punch biopsies and subsequent matched excisions was performed. In total, 493 (67%) lesions were confirmed as invasive cutaneous squamous cell carcinoma on excision, 76% when excluding \"scar\" as a final diagnosis. Tumour diameter > 20mm was highly predictive of cutaneous squamous cell carcinoma (positive predictive value 91.1%). Tumours on the scalp were significantly more likely to demonstrate a final diagnosis of cutaneous squamous cell carcinoma than those on the arm (odds ratio 6.11, 95% confidence interval 3.1,12.0). There was moderate concordance between biopsy and excision in grade of histopathological differentiation. This study demonstrates that clinical high-risk features may be of more value in predicting a diagnosis of cutaneous squamous cell carcinoma than partial punch biopsy. Use of clinical and dermoscopic competencies in assessment of cutaneous tumours rather than reliance on biopsies both avoids delay in patient management in the case of high-risk cutaneous squamous cell carcinoma and may also minimize unnecessary surgical excisions if there is a low clinical index of suspicion of cutaneous squamous cell carcinoma.","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"105 ","pages":"adv40727"},"PeriodicalIF":3.5,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11711690/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142918894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term Satisfaction with CO2 Laser Treatment for Moderate to Major Rhinophyma: A Single-centre Study. 二氧化碳激光治疗中重度鼻肿的长期满意度：一项单中心研究。

IF 3.5 4区医学

Acta dermato-venereologica Pub Date : 2025-01-03 DOI: 10.2340/actadv.v105.41335

Berta Olafsdottir, William Jebril, Philip Curman, Etty Bachar-Wikström, Jakob D Wikström

{"title":"Long-term Satisfaction with CO2 Laser Treatment for Moderate to Major Rhinophyma: A Single-centre Study.","authors":"Berta Olafsdottir, William Jebril, Philip Curman, Etty Bachar-Wikström, Jakob D Wikström","doi":"10.2340/actadv.v105.41335","DOIUrl":"10.2340/actadv.v105.41335","url":null,"abstract":"Rhinophyma, a severe manifestation of rosacea, predominantly affects Caucasian males aged 50-70 and is characterized by thickening and enlargement of the nasal skin. The condition can seriously both impact cosmetic appearance and obstruct nasal breathing. While its appearance is distinct, conditions such as basal cell carcinoma can mimic it, complicating diagnosis. Treatment options for rhinophyma range from medical therapies to surgical interventions, with CO2 laser resurfacing emerging as the gold standard due to its precision and minimal blood loss. This retrospective case series evaluates the long-term efficacy and patient satisfaction of CO2 laser treatment in 11 male patients treated between 2015 and 2023 at the Karolinska University Hospital. The results revealed sustained positive outcomes, with 92% of patients reporting high satisfaction and 55% experiencing improved nasal airflow post-procedure. Despite some instances of hypopigmentation and scarring, no major side effects were reported. The study supports CO2 laser treatment as a safe and effective option for moderate to major rhinophyma in Caucasian male patients with Fitzpatrick skin types I-III. The importance of considering skin type, where extra caution must be employed when treating skin types IV-VI, should be emphasized as the treatment.","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"105 ","pages":"adv41335"},"PeriodicalIF":3.5,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11697134/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142918896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atopic Dermatitis And Intercourse Difficulties : A Cross-sectional Study of the Northern Finland Birth Cohort 1966 Study. 特应性皮炎和性交困难：1966年芬兰北部出生队列研究的横断面研究。

IF 3.5 4区医学

Acta dermato-venereologica Pub Date : 2025-01-03 DOI: 10.2340/actadv.v105.40785

Atte Sopenlehto, Jari Jokelainen, Laura Huilaja, Suvi-Päivikki Sinikumpu

引用次数: 0

Topical Steroid Withdrawal in Atopic Dermatitis: Patient-reported Characterization from a Swedish Social Media Questionnaire. 特应性皮炎的局部类固醇停药：瑞典社交媒体问卷中患者报告的特征

IF 3.5 4区医学

Acta dermato-venereologica Pub Date : 2025-01-03 DOI: 10.2340/actadv.v105.40187

Mikael Alsterholm, Maja Af Klinteberg, Sophie Vrang, Gunnthorunn Sigurdardottir, MariHelen Sandström Falk, Alexander Shayesteh

{"title":"Topical Steroid Withdrawal in Atopic Dermatitis: Patient-reported Characterization from a Swedish Social Media Questionnaire.","authors":"Mikael Alsterholm, Maja Af Klinteberg, Sophie Vrang, Gunnthorunn Sigurdardottir, MariHelen Sandström Falk, Alexander Shayesteh","doi":"10.2340/actadv.v105.40187","DOIUrl":"10.2340/actadv.v105.40187","url":null,"abstract":"Topical steroid withdrawal (TSW) is described as an adverse reaction to topical glucocorticoids (TGCs). A pathophysiological mechanism has not been identified. There are no diagnostic criteria. The aim was to describe patient-reported characteristics of TSW in atopic dermatitis (AD). An observational cross-sectional study was performed by posting a questionnaire for participants, aged ≥18 years, reporting both AD and TSW, in a Swedish TSW-themed Facebook group during 4 weeks in 2023. The questionnaire was accessed by 98 participants, with 82 completing it. Most were female (95%), 18-39 years old (74%), self-diagnosed with TSW (84%), and reported current symptoms of AD and TSW. They defined TSW as dependency on TGCs and adverse reactions to their use. Erythema, desquamation, dryness, and oozing affecting the face, neck, and upper extremities were the most reported signs. Pruritus, sleep disturbance, and signs of anxiety and depression were the most reported symptoms. Recurring episodes of manifestations attributed to TSW were reported by 60%. The personal trigger factor was believed to be TGCs by 93%, and 33% also identified oral glucocorticoids. TGCs were currently used by 21%. Self-reported manifestations of TSW are similar to those of AD but appeared to be distinguishable for the participants and caused considerable morbidity.","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"105 ","pages":"adv40187"},"PeriodicalIF":3.5,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11697140/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142918919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between Atopic Dermatitis and Dementia: Evidence from Systematic Review, Meta-analysis, and Mendelian Randomization. 特应性皮炎与痴呆之间的关联：来自系统评价、meta分析和孟德尔随机化的证据。

IF 3.5 4区医学

Acta dermato-venereologica Pub Date : 2025-01-03 DOI: 10.2340/actadv.v105.41321

Yeon-Su Gwak, Seo-Yeon Kim, Chae-Eon Woo, Kihyuk Shin, Eunjeong Son, Jin-Woo Kim, Sung-Jin Kim, Tae-Jin Song, Hae Ryoun Park, Kihun Kim, Dai Sik Ko, Yun Hak Kim

{"title":"Association between Atopic Dermatitis and Dementia: Evidence from Systematic Review, Meta-analysis, and Mendelian Randomization.","authors":"Yeon-Su Gwak, Seo-Yeon Kim, Chae-Eon Woo, Kihyuk Shin, Eunjeong Son, Jin-Woo Kim, Sung-Jin Kim, Tae-Jin Song, Hae Ryoun Park, Kihun Kim, Dai Sik Ko, Yun Hak Kim","doi":"10.2340/actadv.v105.41321","DOIUrl":"10.2340/actadv.v105.41321","url":null,"abstract":"Recent cohort studies suggest a potential association between atopic dermatitis and dementia, though the evidence remains conflicting. This study aims to elucidate the association between atopic dermatitis and dementia employing systematic review, meta-analysis, and Mendelian randomization (MR). A comprehensive search was performed to select eligible cohort studies using Medline, Embase, Scopus, ScienceDirect, and the Web of Science database. In MR analysis, genomic data from the Genome Wide Association Study (GWAS) (864,982 European individuals) for atopic dermatitis cases and dementia cases were obtained from the MRBase. Statistical analyses included the inverse-variance weighted (IVW) method, sensitivity tests, and MR-PRESSO for outliers. The adjustment accounted for various factors, including sex, age, smoking status, and other medical comorbidities, along with several additional variables. In the systematic review and meta-analysis, 5 longitudinal cohort studies (12,576,235 participants) indicated a significant association between atopic dermatitis and all-cause dementia (adjusted hazard ratio: 1.15, 95% CI: 1.07-1.23). Subgroup analyses revealed an adjusted hazard ratio of 1.18 (95% CI: 1.08-1.27) for Alzheimer's disease in patients with atopic dermatitis, and an adjusted hazard ratio of 1.37 (95% CI: 1.21-1.55) for all-cause dementia in patients with moderate-to-severe atopic dermatitis. However, MR analysis showed no significant causal link between atopic dermatitis and dementia, Alzheimer's disease, vascular dementia, or cognitive performance. While the meta-analysis revealed a significant association, MR analysis did not substantiate a significant causal link. Future research should consider demographic variables and medication influences in unravelling the intricate atopic dermatitis-dementia interplay.","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"105 ","pages":"adv41321"},"PeriodicalIF":3.5,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11697145/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142918874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cell-free DNA Levels in Herpes Zoster: A Cross-sectional Longitudi-nal Study. 带状疱疹无细胞DNA水平：横断面纵向研究。

IF 3.5 4区医学

Acta dermato-venereologica Pub Date : 2025-01-03 DOI: 10.2340/actadv.v105.42137

Chaya Bracha Gordon, Yaron Zenaty, Ayelet Ollech, Gidon Test, Amos Douvdevani, Amir Horev

{"title":"Cell-free DNA Levels in Herpes Zoster: A Cross-sectional Longitudi-nal Study.","authors":"Chaya Bracha Gordon, Yaron Zenaty, Ayelet Ollech, Gidon Test, Amos Douvdevani, Amir Horev","doi":"10.2340/actadv.v105.42137","DOIUrl":"10.2340/actadv.v105.42137","url":null,"abstract":"This study investigates serum cell-free DNA fluctuations in patients with herpes zoster or post-herpetic neuralgia, offering insight into the tissue damage and inflammatory dynamics associated with these conditions. A single-centre combined cross-sectional and longitudinal study was conducted with 59 patients to assess cell-free DNA levels in herpes zoster and post-herpetic neuralgia. Cell-free DNA was extracted from blood samples of patients with herpes zoster or post-herpetic neuralgia and compared with healthy controls. The findings demonstrated elevated cell-free DNA levels in patients with herpes zoster, which remained elevated for 3 months or longer following treat-ment. These results suggest the presence of a subacute inflammatory state after herpes zoster infection. Furthermore, patients who developed post-herpetic neuralgia did not show elevated cell-free DNA levels, while those who did not develop post-herpetic neuralgia exhibited increased levels. This indicates that post-herpetic neuralgia is likely a localized response to prior nerve damage rather than a systemic inflammatory process with acute tissue damage.","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"105 ","pages":"adv42137"},"PeriodicalIF":3.5,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11697138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142918891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0