Acta endocrinologica最新文献_第5页

ECTOPIC LINGUAL THYROID PRESENTING WITH MASSIVE HEMATEMESIS. 舌状甲状腺异位表现为大量呕血。

Acta endocrinologica Pub Date : 2019-04-01 DOI: 10.4183/AEB.2019.244

G. Koç, I. Taşkaldıran, S. Aslan Felek, M. A. Saltabas, T. Omma, A. Akbulut, C. Culha

引用次数: 4

EFFECT OF HYPEROSIDE ON THE INHIBITION OF ADIPOGENESIS IN 3T3-L1 ADIPOCYTES. 金丝桃苷对3t3-l1脂肪细胞脂肪生成的抑制作用。

Acta endocrinologica Pub Date : 2019-04-01 DOI: 10.4183/AEB.2019.165

M. Berkoz

{"title":"EFFECT OF HYPEROSIDE ON THE INHIBITION OF ADIPOGENESIS IN 3T3-L1 ADIPOCYTES.","authors":"M. Berkoz","doi":"10.4183/AEB.2019.165","DOIUrl":"https://doi.org/10.4183/AEB.2019.165","url":null,"abstract":"Context\u0000The inhibition of adipocyte differentiation has a significant role on the prevention of obesity and obesity-associated complications.\u0000\u0000\u0000Objective\u0000In this study, we aimed to detect whether hyperoside is able to inhibit the conversion of pre-adiposits into mature adiposits.\u0000\u0000\u0000Design and Methods\u00003T3-L1 pre-adipocytes were stimulated so as to differentiate into mature adipocytes. Hyperoside in non-cytotoxic concentrations (1, 2, 5, and 10 µM) were separately applied to differentiated 3T3-L1 cells. Oil red O staining was performed and triacylglycerol contents were measured. Furthermore, gene and protein expressions of transcription factors, adipogenic genes and adipokines were examined in order to investigate the effect of hyperoside on adipocyte differentiation.\u0000\u0000\u0000Results\u0000Hyperoside in high concentrations significantly suppressed the adipogenic process by inhibiting the expression of transcription factors and adipogenic genes and reducing lipid accumulation in adipocytes (p<0.05). Low doses of hyperoside are able to inhibit adipogenesis, but higher doses are needed to reduce fat accumulation in mature adipocytes. In the case of maturing preadipocytes, 5 μM of hyperoside exerts its antiadipogenic effect at the early stages of adipogenesis, whereas 10 μM of hyperoside acts at the later stages (p<0.05).\u0000\u0000\u0000Conclusion\u0000These results suggest that hyperoside has a beneficial effect on the prevention and treatment of obesity.","PeriodicalId":6910,"journal":{"name":"Acta endocrinologica","volume":"23 1","pages":"165-172"},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77915878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

FETAL NEUROBLASTOMA. ULTRASOUND AND MRI FINDINGS. 胎儿的神经母细胞瘤。超声和核磁共振检查结果。

Acta endocrinologica Pub Date : 2019-04-01 DOI: 10.4183/AEB.2019.272

L. Pop, M. Rădulescu, O. Toader, Ioan Dumitru Suciu

引用次数: 1

THE EFFECT OF HSP60 ON FERTILIZATION AND PRE-IMPLANTATION EMBRYO DEVELOPMENT IN MICE: AN IN VITRO STUDY. hsp60对小鼠受精和着床前胚胎发育影响的体外研究。

Acta endocrinologica Pub Date : 2019-04-01 DOI: 10.4183/AEB.2019.153

Z. Abdi, S. Mohsenzadeh, I. Jafari Anarkooli, A. Ahmadi, M. Ghorbanlou, M. Arianmanesh

{"title":"THE EFFECT OF HSP60 ON FERTILIZATION AND PRE-IMPLANTATION EMBRYO DEVELOPMENT IN MICE: AN IN VITRO STUDY.","authors":"Z. Abdi, S. Mohsenzadeh, I. Jafari Anarkooli, A. Ahmadi, M. Ghorbanlou, M. Arianmanesh","doi":"10.4183/AEB.2019.153","DOIUrl":"https://doi.org/10.4183/AEB.2019.153","url":null,"abstract":"Context\u0000Heat Shock Protein 60 (HSP60) is a chaperone protein which is involved in proteins transfer and re-folding of proteins.\u0000\u0000\u0000Objective\u0000Importance of HSP60 in sperm capacitation and facility of sperm-oocyte membrane binding was confirmed, therefore in this study the effect of HSP60 on the rate of in vitro fertilization and the cleavage rate in mouse embryo was investigated.\u0000\u0000\u0000Design\u0000Ten male mice and twenty five female mice were involved to collect sperms and oocytes required for this study.\u0000\u0000\u0000Subjects and Methods\u0000Sperms were collected from the epididymis of male mouse and oocytes were collected from the oviduct of female mouse following ovarian hyperstimulation. Then, capacitated sperms and oocytes were placed together in fertilization medium in four groups in the presence of different concentrations of HSP60 (10, 50 and 100 ng/mL) and in the absence of HSP60. After calculation of the fertilization rate, zygotes were transformed into the other medium for development and the cleavage rate was monitored to blastocyst stage.\u0000\u0000\u0000Results\u0000There was not a significant difference in the rate of fertilization between 10 ng/mL HSP60 group and the control group. The rate of fertilization and two-cell embryo development decreased significantly (P≤0.05) in 100 ng/mL HSP60 compared to other experimental and control groups. Further, the rate of two-cell embryo development increased significantly (P≤0.05) in 10 ng/mL HSP60 compared to other experimental and control groups.\u0000\u0000\u0000Conclusions\u0000The present study demonstrated that HSP60 in low dose had a positive effect on two-cell embryo development, however it did not have any significant effect on the fertilization rate. Conversely, HSP60 had adverse effects on the fertilization and cleavage rates at higher doses.","PeriodicalId":6910,"journal":{"name":"Acta endocrinologica","volume":"33 1","pages":"153-157"},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75608009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

FIRST DAY SERUM CALCIUM AND PARATHYROID HORMONE LEVELS AS PREDICTIVE FACTORS FOR SAFE DISCHARGE AFTER THYROIDECTOMY. 第一天血清钙和甲状旁腺激素水平作为甲状腺切除术后安全出院的预测因素。

Acta endocrinologica Pub Date : 2019-04-01 DOI: 10.4183/AEB.2019.225

Daniela Sala, M. Mureșan, S. Voidăzan, T. Cvasciuc, R. Darie, V. Danielopol, S. Mureșan, Ionela Pascanu

{"title":"FIRST DAY SERUM CALCIUM AND PARATHYROID HORMONE LEVELS AS PREDICTIVE FACTORS FOR SAFE DISCHARGE AFTER THYROIDECTOMY.","authors":"Daniela Sala, M. Mureșan, S. Voidăzan, T. Cvasciuc, R. Darie, V. Danielopol, S. Mureșan, Ionela Pascanu","doi":"10.4183/AEB.2019.225","DOIUrl":"https://doi.org/10.4183/AEB.2019.225","url":null,"abstract":"Context\u0000Permanent hypocalcemia is a rare but significant complication of thyroid surgery.\u0000\u0000\u0000Objective\u0000The aim of this study was to identify predictive factors of hypocalcemia and hypoparathyroidism after thyroidectomy.\u0000\u0000\u0000Design\u0000Study included 134 total patients submitted to thyroidectomy from two endocrine units (January 2015 - August 2016).\u0000\u0000\u0000Methods\u0000We measured total serum calcium (sCa) and intact PTH (iPTH) on postoperative day one and 1 month after surgery.\u0000\u0000\u0000Results\u0000118 patients were women with F/M ratio of 7.3/1 and a mean age of 51.8 years. 64 patients were included in group A (iPTH <12 pg/mL) and 70 patients in group B (iPTH >12 pg/mL). sCa and hypocalcemia symptoms were correlated with iPTH, measured 24 hours after surgery. The cut-off value was for sCa 8.05 mg/dL with a sensitivity of 85.29% and a specificity of 88.0% and for iPTH 11.2 pg/mL, with a sensitivity of 82.3% and a specificity of 71.0%. SCa (< 8.05 mg/dL) was a predictive factor with a 99 (IC95%:12.86-761.58) and iPTH (<11.2 pg/mL) with a 10.77 higher risk (CI95%: 3.83-30.30) to be associated with symptoms.\u0000\u0000\u0000Conclusion\u0000SCa and iPTH represent good predictive factors of early and safe hospital discharge and can predict the risk of prolonged and permanent hypoparathyroidism.","PeriodicalId":6910,"journal":{"name":"Acta endocrinologica","volume":"6 1","pages":"225-230"},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80156877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

FROM DIABETES INSIPIDUS TO SELLAR XANTHOGRANULOMA - A "YELLOW BRICK ROAD" DEMANDING TEAM-WORK. 从尿崩症到腹腔黄色肉芽肿——一条要求团队合作的“黄砖路”。

Acta endocrinologica Pub Date : 2019-04-01 DOI: 10.4183/AEB.2019.247

M. Stojanović, E. Manojlović-Gačić, S. Pekic, T. Milojević, D. Miljić, M. Doknic, M. Nikolic Djurovic, Z. Jemuovic, M. Petakov

{"title":"FROM DIABETES INSIPIDUS TO SELLAR XANTHOGRANULOMA - A \"YELLOW BRICK ROAD\" DEMANDING TEAM-WORK.","authors":"M. Stojanović, E. Manojlović-Gačić, S. Pekic, T. Milojević, D. Miljić, M. Doknic, M. Nikolic Djurovic, Z. Jemuovic, M. Petakov","doi":"10.4183/AEB.2019.247","DOIUrl":"https://doi.org/10.4183/AEB.2019.247","url":null,"abstract":"Xanthogranulomas are inflammatory lesions exceptionally rarely occurring in the sellar region. Sellar xanthogranulomas (SXG) result from secondary hemorrhage, infarction, inflammation or necrosis upon existing craniopharyngioma (CP), Rathkès cleft cyst (RCC) or pituitary adenoma (PA), or represent a stage in xanthomatous hypophysitis evolution. \"Pure SXG\" are independent of a preexisting lesion. A 70 year old male patient, laryngeal cancer survivor, presented with central diabetes insipidus (CDI). MRI revealed an intra-suprasellar mass of uncertain origin. Transsphenoidal surgery resulted in an efficient lesion resection with maximal pituitary sparing. Pathological report has confirmed SXG without conclusive identification of preexisting sellar lesion. Age at presentation and gender were atypical for SXG. The most frequent presenting signs of SXG were absent. Most SXG are initially misdiagnosed as CP, RCC or PA. Preoperative clinical and radiological uncertainty may impact operative planning. Differentiating from CP is crucial, due to divergent operative target goals and prognosis. Intraoperative frozen section analysis could guide surgical extensiveness. Close collaboration must include endocrinologist, neuroradiologist, neurosurgeon and pathologist. Quantity and quality of provided tissue are essential for avoiding bias in pathohistological analysis of cystic or heterogenous lesions. Awareness is needed of new pathological entities in the sellar-parasellar region. SXG should be considered in differential diagnosis of CDI-causing sellar lesions.","PeriodicalId":6910,"journal":{"name":"Acta endocrinologica","volume":"18 1","pages":"247-253"},"PeriodicalIF":0.0,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89905233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

LITHIUM-INDUCED NEPHROGENIC DIABETES INSIPIDUS RESPONSIVE TO DESMOPRESSIN. 锂诱发肾源性尿崩症对去氨加压素的反应。

Acta endocrinologica Pub Date : 2019-01-01 DOI: 10.4183/aeb.2019.270

E. Şenocak Taşçı, H. Eralp, K. Kayataş

引用次数: 1

THYROID MALIGNANCY RISK OF INCIDENTAL THYROID NODULES IN PATIENTS WITH NON-THYROID CANCER. 非甲状腺癌患者偶发甲状腺结节的甲状腺恶性风险。

Acta endocrinologica Pub Date : 2015-05-01 DOI: 10.1530/ENDOABS.37.EP913

M. Yalçın, A. Altinova, C. Ozkan, F. Toruner, M. Akturk, O. Akdemir, T. Emiroğlu, D. Gokce, A. Poyraz, F. Taneri, I. Yetkin

{"title":"THYROID MALIGNANCY RISK OF INCIDENTAL THYROID NODULES IN PATIENTS WITH NON-THYROID CANCER.","authors":"M. Yalçın, A. Altinova, C. Ozkan, F. Toruner, M. Akturk, O. Akdemir, T. Emiroğlu, D. Gokce, A. Poyraz, F. Taneri, I. Yetkin","doi":"10.1530/ENDOABS.37.EP913","DOIUrl":"https://doi.org/10.1530/ENDOABS.37.EP913","url":null,"abstract":"Context\u0000Thyroid incidentaloma is a common disorder in endocrinology practice. Current literature regarding the risk of thyroid cancer in incidentalomas found in patients with non-thyroid cancer is limited.\u0000\u0000\u0000Objective\u0000The aim of the present study was to investigate the frequency of thyroid malignancy in thyroid incidentalomas detected in patients with non-thyroid cancer.\u0000\u0000\u0000Design\u0000Case control study.\u0000\u0000\u0000Subjects and Methods\u0000The database of 287 thyroid nodules from 161 patients with a history of non-thyroid cancer followed between 2008 and 2014 were retrospectively evaluated.\u0000\u0000\u0000Results\u0000From 287 thyroid nodules, 69.7 % had a benign final cytology. Thyroid cancer detected in one nodule while follicular neoplasia detected in 4 nodules, atypia of unknown significance (AUS) detected in 10 nodules, Hurthle cell neoplasia detected in 5 nodules and suspicious for malignancy detected in 6 nodules according to fine needle aspiration biopsy results. Metastasis of the non-thyroid cancer to the thyroid gland was detected in 4 nodules. Twenty seven nodules from 15 patients were removed with surgery. There were 3 malignant nodules found after surgery (1 papillary, 1 follicular and 1 medullary cancer). In addition to these three thyroid cancers, two patients with benign nodules had co-incidental thyroid cancer detected after surgery. Finally, 11.1 % of thyroid nodules which underwent thyroid surgery had malignant histopathology except for co-incidental and metastatic cancers.\u0000\u0000\u0000Conclusions\u0000The frequency of thyroid malignancy seems not to be substantially increased in incidental thyroid nodules detected in patients with non-thyroid cancer when these patients were evaluated in nodule-based approach.","PeriodicalId":6910,"journal":{"name":"Acta endocrinologica","volume":"133 10 1","pages":"185-190"},"PeriodicalIF":0.0,"publicationDate":"2015-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79098627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

The influence of prominal on thyroid function in the rat. 日珥对大鼠甲状腺功能的影响。

Acta endocrinologica Pub Date : 2010-09-02 DOI: 10.1002/RECL.19550740320

F. Schwarz

引用次数: 0

Life with Turner's syndrome--a psychosocial report from 22 middle-aged women. 特纳综合症患者的生活——来自22名中年妇女的心理社会报告。

Acta endocrinologica Pub Date : 1994-04-01 DOI: 10.1097/00006254-199404000-00019

L. Sylvén, C. Magnusson, K. Hagenfeldt, B. V. VON Schoultz

{"title":"Life with Turner's syndrome--a psychosocial report from 22 middle-aged women.","authors":"L. Sylvén, C. Magnusson, K. Hagenfeldt, B. V. VON Schoultz","doi":"10.1097/00006254-199404000-00019","DOIUrl":"https://doi.org/10.1097/00006254-199404000-00019","url":null,"abstract":"Twenty-two middle-aged women (median age 44.5 years) with Turner's syndrome were interviewed about family background, social identity, emotional development, relations, female identity, sexuality and reactions to the diagnosis, to evaluate how the condition has affected their lives and coping style. During the years preceding the diagnosis and hormonal replacement therapy (HRT) they had often isolated themselves as they felt different from their peers. Ovarian failure and infertility, not the body height, were the major problems for most of the women. Infertility had affected the women very deeply and many felt depressed because of this. Adolescent behaviour, a feeling of chronic inferiority or a feeling of grief were different ways of coping with the situation. Median age at sexual debut was 19.5 years. Painful intercourse related to vaginal constriction and sore membranes was commonly reported. Most of the women had stopped HRT because of side-effects. Many of the problems experienced by the women could have been avoided if proper HRT had been administered in due time and on a long-term basis. This emphasizes the importance of regular contact with a gynecologist of special training and interest.","PeriodicalId":6910,"journal":{"name":"Acta endocrinologica","volume":"29 1","pages":"188-94"},"PeriodicalIF":0.0,"publicationDate":"1994-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79315726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 24