L. Pop, M. Rădulescu, O. Toader, Ioan Dumitru Suciu
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Acquired partial lipodystrophy is a rare disease with slightly over 250 patients reported so far. The disease is characterized by the loss of adipose tissue from the face, upper limbs, and the upper trunk. Fat loss usually starts in childhood and early adulthood, and the disease is more common in females. Some patients may exhibit an accumulation of fat in the lower part of the body. Metabolic abnormalities secondary to insulin resistance may develop in patients with acquired partial lipodystrophy; however, they are relatively less frequent compared to other subtypes of lipodystrophy. Here, we present a 23-year-old female with acquired partial lipodystrophy who presented with acanthosis nigricans which is a rare event in the case of acquired partial lipodystrophy.
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