中国疾病预防控制中心周报最新文献

{"title":"Genomic Insights into the 2024 HAdV-14p1 Strain in China: Traced to Early Prevalent Strains.","authors":"Yali Jin, Jiangxia Wang, Naiying Mao, Chunyu Zhu, Haiqing Zhou, Weiyan He, Hao Ding, Baicheng Xia, Aili Cui, Yan Zhang, Zhen Zhu, Hongmei Xu","doi":"10.46234/ccdcw2026.033","DOIUrl":"https://doi.org/10.46234/ccdcw2026.033","url":null,"abstract":"<p><strong>Introduction: </strong>Human adenovirus type 14 variant p1 (HAdV-14p1) has been associated with severe respiratory infections worldwide. However, no cases of HAdV-14p1 infection have been reported in China since 2019. HAdV-14 was unexpectedly identified in 2024 in a pediatric patient hospitalized with bronchopneumonia in Chongqing, China. This study aims to elucidate the genetic characteristics of this strain and determine its phylogenetic relationship with previously circulating domestic and international strains.</p><p><strong>Methods: </strong>Whole-genome sequencing was performed on the HAdV-14 strain Chongqing2024-115, followed by comprehensive phylogenetic and genetic variation analyses using all publicly available global HAdV-14 genome sequences from the GenBank database.</p><p><strong>Results: </strong>Genome-based phylogenetic analysis classified global HAdV-14 strains into two well-supported clades: the HAdV-14 prototype clade and the variant HAdV-14p1 clade. The latter was further subdivided into three distinct subclades (I-III). Chongqing2024-115 clustered closely with earlier HAdV-14p1 subclade III and isolates from Beijing (2012) and Gansu (2013), showing high sequence identity (99.7%-99.9%). Compared with the genome of the HAdV-14 prototype strain (de Wit, AY803294), all three HAdV-14p1 subclades shared 99 specific nucleotide variations, including a six-nucleotide deletion in the knob domain of the fiber gene (nt751-756). The identification of subclade-specific variations and mutations unique to strain Chongqing2024-115 indicates ongoing microevolution within the HAdV-14p1 clade.</p><p><strong>Conclusions: </strong>Our results confirm that the contemporary HAdV-14p1 strain shares a common genetic ancestry with earlier Chinese subclade III strains. Considering the association between HAdV-14p1 and severe disease, sustained surveillance is essential to understand better its prevalence, evolution, and impact on public health in China.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"8 8","pages":"195-200"},"PeriodicalIF":2.9,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13056505/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147647769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reported Cases and Deaths of National Notifiable Infectious Diseases - China, December 2025.","authors":"","doi":"10.46234/ccdcw2026.032","DOIUrl":"https://doi.org/10.46234/ccdcw2026.032","url":null,"abstract":"","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"8 7","pages":"193-194"},"PeriodicalIF":2.9,"publicationDate":"2026-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13058458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147647677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First Human Case of <i>Streptococcus parasuis</i> Infection - Henan Province, China, 2025.","authors":"Pengyun Zhang, Shuangling Li, Xue Luo, Yafei Li, Xiaolong Ma, Hui Li, Xin Zhu, Yinxia Zhu","doi":"10.46234/ccdcw2026.031","DOIUrl":"https://doi.org/10.46234/ccdcw2026.031","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong><i>Streptococcus parasuis</i> was historically classified as serotypes 20, 22, and 26 of <i>Streptococcus suis</i>. Limited availability of suitable detection methods has resulted in scarce case reports, which have predominantly focused on bacterial identification and pathogenic mechanisms rather than comprehensive epidemiological investigations.</p><p><strong>What is added by this report?: </strong>This study confirmed the first documented human case of <i>Streptococcus parasuis</i> infection in Henan Province through comprehensive genetic sequencing. Phylogenetic analysis revealed that this strain exhibits substantial genetic divergence from previously isolated domestic strains. Notably, the patient reported no documented history of livestock contact, indicating that environmental exposure may represent a critical transmission route.</p><p><strong>What are the implications for public health practice?: </strong>This investigation underscores the urgent need to strengthen environmental surveillance and implement rigorous disinfection protocols for <i>Streptococcus parasuis</i>, while expanding monitoring efforts to encompass both high-risk occupational groups and the general population. Development and deployment of rapid diagnostic reagents should be prioritized to prevent underdiagnosis in cases lacking documented livestock exposure history.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"8 7","pages":"188-192"},"PeriodicalIF":2.9,"publicationDate":"2026-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13054701/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147640691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-City Outbreak of <i>Staphylococcus aureus</i> Infections Linked to Durian Mille-Feuille Cakes - Shandong Province, China, May-June 2025.","authors":"Maoqiang Zhuang, Xinpeng Li, Peirui Xiao, Zhengqiao Kong, Jian Song, Zunhua Chu, Liansen Wang","doi":"10.46234/ccdcw2026.029","DOIUrl":"https://doi.org/10.46234/ccdcw2026.029","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong><i>Staphylococcus aureus</i> (<i>S. aureus</i>) is a Gram-positive, halotolerant bacterium. Enterotoxin-producing strains of <i>S. aureus</i> can cause foodborne outbreaks in humans, with incubation periods typically ranging from 1 to 6 hours.</p><p><strong>What is added by this report?: </strong>Investigation identified 22 cases aged 9-61 years. All patients experienced diarrhea. Durian mille-feuille cakes were identified as the suspected food vehicle. cgMLST analysis demonstrated that clinical isolates, food samples, and food handler isolates exhibited minimal genetic divergence.</p><p><strong>What are the implications for public health practice?: </strong>Comprehensive hygiene control measures throughout the production chain are critical for cold-processed pastries, encompassing thorough fruit sanitation, rigorous microbial monitoring of raw ingredients, robust employee health surveillance, and uninterrupted cold chain maintenance with storage temperatures consistently below 4 °C. Franchise food operations demand enhanced regulatory oversight despite decentralized supply chains, underscoring the necessity for uniform food safety protocols implemented across all retail outlets.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"8 7","pages":"175-180"},"PeriodicalIF":2.9,"publicationDate":"2026-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13054700/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147640715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Local Chikungunya Fever Outbreak Field Investigation - Fujian Province, China, 2025.","authors":"Shenggen Wu, Jiangyi Liu, Zhangbin Tang, Xiaoling Chen, Yuedong Lin, Jiawei Lin, Ruyi Guo, Weiming Wang, Yuwei Weng","doi":"10.46234/ccdcw2026.030","DOIUrl":"https://doi.org/10.46234/ccdcw2026.030","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>In China, both imported and locally transmitted Chikungunya fever (CHIKF) cases have been documented in southern provinces. The urban transmission chain comprises three critical links: viremic humans, the extrinsic incubation period (EIP, 2-10 days), and the intrinsic incubation period (IIP, 1-12 days).</p><p><strong>What is added by this report?: </strong>This outbreak in Fujian Province demonstrated that in a non-endemic area for CHIKF, the introduction of an imported viremic case combined with the presence of local <i>Aedes</i> mosquitoes can establish local transmission within approximately 9 days through mosquito vectors.</p><p><strong>What are the implications for public health practice?: </strong>In regions with established <i>Aedes</i> mosquito populations, imported CHIKF cases may trigger import-driven local transmission if vector control measures are delayed or inadequately implemented. During epidemic seasons, upon identifying imported cases, public health authorities should immediately map the patients' viremic-phase activity areas, delineate high-risk zones, and implement targeted mosquito elimination measures.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"8 7","pages":"181-187"},"PeriodicalIF":2.9,"publicationDate":"2026-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13054704/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147640747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Foodborne Outbreak Caused by ST8(CC8)-<i>spa</i> t024 Methicillin-Sensitive <i>Staphylococcus aureus</i> Harboring <i>sea</i>, <i>seq</i>, and <i>sek</i> - Taizhou City, Zhejiang Province, China, February 2025.","authors":"Weiwei Shen, Xiaoyue Wei, Haiyan Hu, Guiwei Zhu, Ying Sheng, Ning Wang, Tianlan Pang, Luwei Wang, Lingbo Wang, Li Zhan, Zhangnyu Yang, Xiaomei Yan, Haijiang Lin","doi":"10.46234/ccdcw2026.028","DOIUrl":"https://doi.org/10.46234/ccdcw2026.028","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>The <i>Staphylococcus aureus</i> (S. aureus) sequence type 8 (ST8) clone has emerged as a dominant epidemic clone strongly associated with community-associated methicillin-resistant <i>S. aureus</i> (CA-MRSA) infections worldwide. However, documentation of this clone in China remains sparse.</p><p><strong>What is added by this report?: </strong>This report documents the first staphylococcal food poisoning outbreak in Zhejiang Province, China, caused by methicillin-susceptible <i>S. aureus</i> (MSSA) of the ST8 (CC8)-<i>spa</i> t024 lineage harboring enterotoxin genes <i>sea</i>, <i>seq</i>, and <i>sek</i>. Whole-genome phylogenetic analysis revealed that the outbreak strains belonged to a distinct evolutionary subclade (Clade II.1). These strains demonstrated close genetic relatedness to previously reported European lineages.</p><p><strong>What are the implications for public health practice?: </strong>The identification of the ST8-<i>spa</i> t024 MSSA strain carrying <i>sea</i>, <i>seq</i>, and <i>sek</i> genes underscores the substantial public health risk in China. This finding highlights the emerging threat of foodborne illnesses caused by novel or under-recognized <i>S. aureus</i> ST8 strains and emphasizes the urgent need for enhanced surveillance of CA-<i>S. aureus</i> among food handlers to prevent future outbreaks.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"8 7","pages":"169-174"},"PeriodicalIF":2.9,"publicationDate":"2026-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13054699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147640708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accessible Blood Based Biomarkers Reflecting Inflammation-Lipid Dysregulation in Silicosis Progression - Jiangsu Province, China, 2021-2024.","authors":"Rong Jiang, Qianqian Gao, Lang Zhou, Feng Shi, Yunfeng Hua, Feifei Wang, Zhen Hong, Lei Han","doi":"10.46234/ccdcw2026.025","DOIUrl":"https://doi.org/10.46234/ccdcw2026.025","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>Silicosis, an occupational lung disease caused by exposure to silica dust, is characterized by persistent inflammation and lipid dysregulation. Clinicians typically rely on radiographic imaging and pulmonary function tests instead of accessible blood-based biomarkers to quantify inflammation-lipid imbalance and predict functional decline in disease management.</p><p><strong>What is added by this report?: </strong>We evaluate two novel hematological indices - Neutrophil-to-HDL Ratio (NHR) and Platelet-to-HDL Ratio (PHR) - in 160 patients with silicosis and 123 silica-exposed controls from Jiangsu Province, China. Both the NHR and PHR of patients in the silicosis group are significantly higher than those in the control group, with the highest levels observed in advanced stages (Stage II-III). Both ratios show significant negative correlations with lung function decline (FVC%, FEV₁%, FEV₁/FVC), and these correlations strengthen in patients with advanced silicosis.</p><p><strong>What are the implications for public health practice?: </strong>NHR and PHR are low-cost, accessible biomarkers of inflammation-lipid dysregulation during the progression of silicosis. Incorporating these ratios into routine occupational health screening for silica-exposed workers could serve as a complementary method to radiographic examination or spirometry tests, thereby improving silicosis monitoring and management.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"8 6","pages":"141-147"},"PeriodicalIF":2.9,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13054698/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147640639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intervention of Hypertension by Occupational Health Management Among Dock Workers - Shenzhen City, Guangdong Province, China, 2020-2024.","authors":"Naixing Zhang, Wei Zhou, Jinlin Wang, Wenting Feng, Qiujie Sheng, Aipin Xiao, Dafeng Lin, Shaofan Weng","doi":"10.46234/ccdcw2026.024","DOIUrl":"https://doi.org/10.46234/ccdcw2026.024","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>Hypertension predisposes dock workers to higher health risks in their work environments, requiring urgent intervention via comprehensive health management.</p><p><strong>What is added by this report?: </strong>This study explored occupational health management in hypertension among dock workers and found that occupational health management measures helped reduce the blood pressure of patients with hypertension, curb the incidence, and slow the growth rate of its prevalence.</p><p><strong>What are the implications for public health practice?: </strong>The intervention measures adopted in this study should be promoted in similar occupational environments.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"8 6","pages":"135-140"},"PeriodicalIF":2.9,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13054697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147640688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Classroom Environmental Determinants of Poor Vision in Chinese Schoolchildren - Guangdong Province, China, 2024.","authors":"Jingxi Feng, Jing Jiang, Meng Li, Rong Liu, Qiuxia Chen, Chengshu Yang, Jiwei Niu, Lin Xu, Yabin Qu","doi":"10.46234/ccdcw2026.026","DOIUrl":"https://doi.org/10.46234/ccdcw2026.026","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>The prevalence of poor vision among Chinese children and adolescents has been progressively increasing, constituting a significant public health concern. As the primary visual setting for students, the classroom environment may have a profound impact on ocular health.</p><p><strong>What is added by this report?: </strong>This study revealed a poor vision detection rate of 60.22% among primary and junior high school students. The statistically significant relevant factors were blackboard reflectance, desk-chair allocation compliance rate, and desktop illuminance uniformity.</p><p><strong>What are the implications for public health practice?: </strong>This study provides scientific evidence and prioritizes recommendations for modifying classroom environments. It supports targeted environmental interventions as a priority in school-based myopia prevention strategies.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"8 6","pages":"148-153"},"PeriodicalIF":2.9,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13054696/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147640752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of an Infectious Diarrhea Outbreak Associated with Direct Drinking Water in a High School - Baisha County, Hainan Province, China, November 2024.","authors":"Faren Li, Li Qiu, Yan Jin, Huiwen Gao, Jianhua Dong, Meirong Huang, Shennv Xue, Yunhui Su, Xianglin Huang, Ren Qiu, Shuyun Xie","doi":"10.46234/ccdcw2026.022","DOIUrl":"https://doi.org/10.46234/ccdcw2026.022","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>Diarrheagenic <i>Escherichia coli</i> (DEC) represents a major causative agent of diarrheal outbreaks in China. Transmission occurs through consumption of contaminated food or drinking water and through person-to-person contact, frequently resulting in clustered infections.</p><p><strong>What is added by this report?: </strong>Between November 6 and 20, 2024, an outbreak of infectious diarrhea affected 344 students at a high school in Baisha County, Hainan Province. Comprehensive field epidemiological and environmental investigations, combined with laboratory testing, identified DEC as the causative agent. This outbreak was primarily attributed to consumption of direct drinking water supplied by substandard water dispensers that inadequately filtered contaminated municipal water.</p><p><strong>What are the implications for public health practice?: </strong>Substandard direct drinking water dispensers equipped only with polypropylene (PP) cotton and activated carbon filters cannot effectively remove microorganisms. When source water is contaminated, the warm water produced by mixing cold and hot water outputs from such dispensers fails to meet required hygienic standards. Ensuring municipal drinking water compliance and strict implementation of quality and safety management regulations for direct drinking water dispensers are therefore essential for drinking water safety. The public and all relevant sectors should be reminded to purchase and use only qualified direct drinking water dispensers, particularly in schools, collective establishments, and public venues.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"8 6","pages":"161-167"},"PeriodicalIF":2.9,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13054703/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147640695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}