中国疾病预防控制中心周报最新文献

{"title":"Epidemiological Characteristics of Human Respiratory Syncytial Virus in Children with Acute Respiratory Infection - Shijiazhuang City, Hebei Province, China, 2021-2023.","authors":"Yan Li, Guangyue Han, Caixiao Jiang, Wenhao Zhou, Minghao Geng, Nana Guo, Wentao Wu, Yamei Wei, Lanfen Liu, Xu Han, Guofan Li, Shangze Liu, Zhihuai Xing, Qi Li","doi":"10.46234/ccdcw2025.038","DOIUrl":"10.46234/ccdcw2025.038","url":null,"abstract":"<p><strong>Introduction: </strong>Human respiratory syncytial virus (HRSV) is the predominant respiratory pathogen causing acute respiratory tract infection (ARTI). Globally, HRSV infection represents the leading cause of acute respiratory morbidity and hospitalization in children under 2 years of age. HRSV infection continues to pose a significant public health challenge worldwide. Through epidemiological surveillance of HRSV in children with ARTI, we can elucidate its incidence patterns and epidemic characteristics to inform evidence-based prevention and control strategies.</p><p><strong>Methods: </strong>We collected upper and lower respiratory tract specimens and clinical data from children under 14 years of age with ARTI. HRSV was detected using Real-time Polymerase Chain Reaction to analyze its incidence and epidemic characteristics.</p><p><strong>Results: </strong>Among 1,440 specimens, the overall HRSV detection rate was 7.8% (HRSVA and HRSVB detection rates were 4.0% and 3.8%, respectively). Detection rates peaked in spring (12.2%), followed by winter (10.3%), with the lowest rates in autumn (2.8%) (<i>P</i><0.05). HRSVB was the dominant subtype throughout 2021, while HRSVA predominated during 2022 and the first half of 2023. Detection rates were significantly higher in children under 5 years compared to older children, with lower respiratory tract infections in the 0-2 years age group showing notably higher detection rates (18.1%) than upper respiratory tract infections (8.1%) (<i>P</i><0.05).</p><p><strong>Conclusions: </strong>HRSV exhibited consistent circulation among children with ARTI in the Shijiazhuang area from 2021 to 2023, characterized by winter and spring outbreaks and alternating predominance of subtypes A and B. Infections predominantly affected children under 5 years of age.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 7","pages":"239-243"},"PeriodicalIF":4.3,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832439/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Analysis of Epidemiological and Clinical Characteristics Between Mpox Cases with and Without HIV - China, 2023.","authors":"Yichen Jin, Qianqian Qin, Chao Li, Houlin Tang, Dapeng Zhang, Wenqing Bai, Fangfang Chen, Peilong Li, Pairidai Duolaitiniyazi, Ruiqi Ren, Dan Li, Nijuan Xiang, Guoqing Shi, Fan Lyu, Qun Li","doi":"10.46234/ccdcw2025.037","DOIUrl":"10.46234/ccdcw2025.037","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to analyze the epidemiological characteristics and clinical symptoms of mpox cases with and without human immunodeficiency virus (HIV) reported in China in 2023, providing evidence for coordinated prevention and control strategies for both infections.</p><p><strong>Method: </strong>All confirmed mpox cases reported in 2023 were extracted from China's Information System for Disease Control and Prevention. Data were collected from the surveillance system and epidemiological investigations. Statistical analyses were performed using SPSS 24.0, with group comparisons conducted using <i>t-</i>tests and chi-square tests.</p><p><strong>Results: </strong>Among 1,712 confirmed mpox cases in China during 2023, 802 (46.8%) were people with human immunodeficiency virus (PWH). Of the 1,702 male cases, 97.3% of PWH and 91.1% of those without HIV self-identified as men who have sex with men (MSM). Age distribution showed 79.4% of PWH and 87.6% of those without HIV were under 40 years old, while 64.2% of PWH and 71.3% of those without HIV were reported from eastern regions. Cardinal symptoms at diagnosis occurred at similar rates between those with and without HIV, including rash (90.9% <i>vs</i>. 93.4%), fever (52.5% <i>vs.</i> 53.8%), and lymphadenopathy (23.8% <i>vs.</i> 25.4%). Among coinfected cases, individuals diagnosed with HIV after mpox or within one year before mpox demonstrated higher rates of immunodeficiency and lower rates of HIV viral suppression.</p><p><strong>Conclusion: </strong>Male mpox cases with HIV was more likely to be MSM, older, and reported from central and western regions compared to those without HIV. No significant differences were observed in cardinal symptom occurrence between groups. These findings emphasize the importance of implementing integrated prevention strategies targeting both HIV and mpox, particularly among key populations.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 7","pages":"233-238"},"PeriodicalIF":4.3,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variations in Prevalence and Characteristics of Rotavirus Diarrhea Among Outpatients - Shanghai Municipality, China, 2017-2023.","authors":"Xiaohuan Gong, Xiaozhou Kuang, Yaxu Zheng, Sheng Lin, Wenjia Xiao, Min Chen, Jian Chen, Zheng Teng, Hao Pan","doi":"10.46234/ccdcw2025.039","DOIUrl":"10.46234/ccdcw2025.039","url":null,"abstract":"<p><strong>Introduction: </strong>This study investigated temporal changes in rotavirus group A (RVA) prevalence, epidemiological characteristics, and genotype distribution patterns among diarrhea outpatients in Shanghai Municipality, China.</p><p><strong>Methods: </strong>We conducted prospective active surveillance of diarrheal disease in pediatric and adult outpatients in Shanghai. Stool specimens were analyzed for five viral and twelve bacterial pathogens. Real-time reverse transcription polymerase chain reaction (rRT-PCR) was employed for RVA detection, followed by genotyping of RVA-positive specimens through partial amplification of VP7 and VP4 genes.</p><p><strong>Results: </strong>The study analyzed 2,331 diarrhea cases in children aged 0-14 years and 8,418 cases in individuals aged ≥15 years between January 2017 and December 2023. Overall RVA positivity rates decreased significantly from 7.43% in 2017 to 1.19% in 2023 (<i>P</i>=0.024). The most pronounced decline occurred in children aged 2-5 years, where positivity rates fell from 13.08% to 1.72%. Adults aged ≥30 years also showed a substantial reduction. Among RVA-positive pediatric cases (≤14 years), the proportion of cases aged 6-14 years increased from 2.33% to 18.18%. While G9P[8] remained the predominant strain, its prevalence decreased from 77.78% to 31.25%, concurrent with the emergence of G8P[8] strains.</p><p><strong>Conclusions: </strong>RVA prevalence has shown a marked decline since 2018-2019, accompanied by a shift in age distribution toward older children. The diminishing dominance of G9P[8] strains coincided with the emergence of G8P[8] strains. Continued epidemiological and genetic surveillance of rotavirus diarrhea, coupled with real-world effectiveness evaluations of domestic vaccines, remains crucial for optimizing rotavirus immunization strategies.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 7","pages":"244-252"},"PeriodicalIF":4.3,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832438/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Factors Influencing the Survival Times of Chinese Patients with Probable Creutzfeldt-Jacob Disease - China, 2020-2022.","authors":"Weiwei Zhang, Yuan Wang, Ruhan A, Donglin Liang, Kang Xiao, Donghua Zhou, Xiaoxi Jia, Bing Xu, Rundong Cao, Cao Chen, Xiaoping Dong, Qi Shi","doi":"10.46234/ccdcw2025.040","DOIUrl":"10.46234/ccdcw2025.040","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>The clinical durations of sporadic Creutzfeldt-Jacob disease (sCJD) patients typically do not exceed 2 years, though considerable variation exists. The factors influencing survival among Chinese sCJD patients remain incompletely characterized.</p><p><strong>What is added by this report?: </strong>A comprehensive evaluation of 31 factors across 7 categories was conducted in a retrospective cohort of 300 probable Chinese sCJD patients. The analysis revealed that patients over 65 years of age at onset, those presenting with pyramidal or extrapyramidal dysfunction, those showing high signal intensity in caudate/putamen on magnetic resonance imaging, and those not receiving nasal feeding demonstrated significantly shorter survival times.</p><p><strong>What are the implications for public health practice?: </strong>This study provides the first systematic documentation of potential risk factors affecting survival times in Chinese sCJD patients, establishing an evidence base for developing and implementing targeted intervention strategies.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 7","pages":"253-260"},"PeriodicalIF":4.3,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Imported Yellow Fever Adverse Events Following Immunization Case Identified by Targeted Next-Generation Sequencing - Guangdong Province, China, October 2024.","authors":"Xin Zhang, Zhe Liu, Jieling Wang, Jianhua Huang, Shen Huang, Biao Di, Jiandong Li, Qiqi Tan, Xiaolu Shi, Min Kang, Baisheng Li","doi":"10.46234/ccdcw2025.041","DOIUrl":"10.46234/ccdcw2025.041","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>Yellow fever (YF) is a highly lethal mosquito-borne infectious disease endemic to tropical regions for which no antiviral treatments currently exist. Vaccination remains the most effective preventive measure and is recommended by the World Health Organization (WHO) for YF control and prevention. However, the YF vaccination associated Adverse Events following Immunization (AEFI) cases occur globally occasionally.</p><p><strong>What is added by this report?: </strong>This report describes the first imported suspected YF case in China in 2024, which was a 46-year-old Peruvian man with a recent YF vaccination history. Guangdong CDC employed Targeted Next-Generation Sequencing (tNGS) analysis to determine whether the patient was infected by the wild-type YF virus strain or experienced an AEFI. tNGS analysis successfully yielded a 10.2 kb viral genomic sequence and BLAST analysis revealed high similarity to the YF vaccine strain 17D-213. Phylogenetic analysis classified the sequence within the West Africa II genotype, clustering with the 17D vaccine strain and showing 99.89%-99.79% homology with vaccine strains, while demonstrating only 85.4%-84.9% similarity to wild-type YF virus strains from South America. Based on this evidence, an expert panel consultation concluded that this case represented YF AEFI.</p><p><strong>What are the implications for public health practice?: </strong>The implementation of tNGS technology enables more precise and expeditious pathogen sequencing, providing critical evidence for accurate disease diagnosis and informed public health interventions.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 7","pages":"261-264"},"PeriodicalIF":4.3,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832440/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection Rate and Risk Factors of Abnormal Spinal Curvature Among Children and Adolescents - Jiangsu Province, China, 2021-2023.","authors":"Yuanyuan Li, Yao Xiang, Yan Wang, Xiyan Zhang, Yiliang Xin, Hui Xue, Xiaoyan Ni, Jie Yang, Wei Du","doi":"10.46234/ccdcw2025.033","DOIUrl":"10.46234/ccdcw2025.033","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>Spinal curvature abnormalities have emerged as a major public health challenge for children and adolescents in China, with detection rates showing a concerning upward trend in recent years.</p><p><strong>What is added by this report?: </strong>This population-based surveillance study revealed a 2.1% detection rate of abnormal spinal curvature among children and adolescents aged 6-17 years in Jiangsu Province. The findings emphasize the critical need for early intervention programs targeting modifiable risk factors, including insufficient physical activity, inadequate sleep duration, and improper reading and writing posture.</p><p><strong>What are the implications for public health practice?: </strong>The increasing burden of abnormal spinal curvature requires targeted attention, particularly for high school students and females during growth spurts. A comprehensive approach combining early lifestyle interventions, such as adequate outdoor activities, with appropriate referrals to public health specialists and orthopedic surgeons may enhance risk mitigation. Success in addressing this challenge requires coordinated multisectoral collaboration and active parental engagement.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 6","pages":"208-216"},"PeriodicalIF":4.3,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832448/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variation in and Factors Associated with Youth Self-Harm in College Students - Jiangsu Province, China, 2019-2023.","authors":"Hui Xue, Xin Wang, Yiwen Hua, Xiyan Zhang, Wenyi Yang, Xiaoyan Ni, Yong Tian, Lijun Fan, Jie Yang, Wei Du","doi":"10.46234/ccdcw2025.034","DOIUrl":"10.46234/ccdcw2025.034","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>Self-harm represents a significant public health challenge that disproportionately affects young adults. Understanding individual- and institutional-level risk factors is crucial for developing and implementing effective mental wellness intervention programs for college students.</p><p><strong>What is added by this report?: </strong>The prevalence of youth self-harm fluctuated between 2.21% and 3.83% from 2019 to 2023. Risk factors associated with self-harm included unhealthy lifestyle behaviors, particularly internet addiction, while the implementation of regular family psychological forums was associated with reduced self-harm risk.</p><p><strong>What are the implications for public health practice?: </strong>Effective campus-based psychosocial support systems must incorporate person-centered approaches and context-specific needs, optimize resource allocation through targeted interventions, and prioritize high-risk groups exhibiting unhealthy lifestyle behaviors.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 6","pages":"217-224"},"PeriodicalIF":4.3,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence, Risk Factors, and Relevant Consequences of Mobile Phone Dependence Among Middle School Students - Guangzhou City, Guangdong Province, China, 2023.","authors":"Chang Wang, Haiyuan Zhu, Rong Lin, Hui Liu, Jinrong Li, Minying Sun, Weiquan Lin, Qin Zhou, Bing Huang, Jierong Zhao, Yingyu Yang, Ying Li, Qiqi Wu, Runquan Zhang, Xiaomei Dong","doi":"10.46234/ccdcw2025.032","DOIUrl":"10.46234/ccdcw2025.032","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>The risk factors for mobile phone dependence (MPD) remain inconsistent and debated in the literature. Previous studies in China reported MPD prevalence rates of 26.2% among junior high students and 27.9% among senior high students in 2012. A 2021 study in Guangzhou City found a prevalence of 13.5% among first-year senior high students.</p><p><strong>What is added by this report?: </strong>This study reveals that the overall MPD prevalence among middle school students in Guangzhou was 10.0% in 2023, with distinct rates between junior high (7.3%) and senior high (12.4%) students. The research identifies key risk factors for MPD development and documents injury patterns associated with excessive phone use.</p><p><strong>What are the implications for public health practice?: </strong>These findings provide an evidence base for developing targeted interventions to reduce both MPD occurrence and associated injuries among middle school students.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 6","pages":"201-207"},"PeriodicalIF":4.3,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in HPV-Associated Cervical Cancer Dynamic Modelling for Prevention and Control Evaluation.","authors":"Yuxi He, Han Ni, Wentao Kuang, Liuyi Fu, Shanghui Yi, Wenting Zha, Yuan Lyu","doi":"10.46234/ccdcw2025.035","DOIUrl":"10.46234/ccdcw2025.035","url":null,"abstract":"<p><p>Cervical cancer is a common malignancy in women, with persistent human papillomavirus (HPV) infection as its primary cause. Understanding the progression from HPV infection to cervical cancer is crucial. Mathematical models play a key role in converting clinical trial data into long-term health forecasts, helping decision-makers tackle challenges posed by limited data and uncertain outcomes. This paper reviews transmission dynamics models and advancements in simulating HPV transmission leading to cervical cancer. It evaluates preventive and control measures, focusing on the impact of HPV vaccination across different vaccine types, doses, age groups, and both genders. These model-based assessments aim to provide insights for developing effective strategies to prevent and control HPV-related cervical cancer.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 6","pages":"225-229"},"PeriodicalIF":4.3,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832444/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical Activity Patterns Across Life Domains in Chinese Older Adults Aged 60-79 Years - China, 2020.","authors":"Chaoqun Fan, Qiang Feng, Jingjing Wang, Chengdong Xu, Yuehua Hu, Zonghao Sun, Kai Xu, Mei Wang","doi":"10.46234/ccdcw2025.031","DOIUrl":"10.46234/ccdcw2025.031","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>Physical inactivity among older adults is increasing globally. Analyzing the characteristics and influencing factors of physical activity patterns (PAPs) can inform the design of targeted physical activity (PA) promotion strategies for diverse subgroups.</p><p><strong>What is added by this report?: </strong>Analysis of national data from 2020 revealed three distinct PAPs among Chinese older adults across life domains: low activity (LA) cluster (53.3%), active leisure (AL) cluster (31.4%), and active home (AH) cluster (15.3%). The AL cluster demonstrated superior psychological status, physical fitness, and built environment conditions compared to both AH and LA clusters. The AH cluster exhibited better physical fitness and built environment characteristics than the LA cluster.</p><p><strong>What are the implications for public health practice?: </strong>The distinct characteristics among clusters suggest that targeted interventions and policies may be beneficial for each subgroup. These interventions should incorporate enhanced psychosocial support, built environment modifications, and evidence-based guidance for physical fitness improvement, specifically tailored to each cluster's unique characteristics and needs.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 6","pages":"195-200"},"PeriodicalIF":4.3,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}