中国疾病预防控制中心周报Pub Date : 2025-10-10Epub Date: 2025-09-19DOI: 10.46234/ccdcw2025.218
Xi Li, Jue Liu
{"title":"Artificial Intelligence in Health and Medicine: Progress, Challenges, and Recommendations.","authors":"Xi Li, Jue Liu","doi":"10.46234/ccdcw2025.218","DOIUrl":"https://doi.org/10.46234/ccdcw2025.218","url":null,"abstract":"<p><p>Artificial intelligence (AI) has broadly reshaped health and medicine, benefiting clinicians, patients, and health systems. However, technical, regulatory, and ethical challenges exist in the application of medical AI, ranging from data scarcity to fairness. We provide our perspective on how to address the major challenges facing widespread clinical adoption from both technical (e.g., building high-quality datasets, using larger and more diverse datasets for training, creating problem formulations that go beyond supervised learning, and combining human skills with AI tools) and ethical (e.g., using highly secure data platforms and strengthening governmental legislation) perspectives.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 41","pages":"1291-1295"},"PeriodicalIF":2.9,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12518967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国疾病预防控制中心周报Pub Date : 2025-10-10DOI: 10.46234/ccdcw2025.220
Tao Zhang, Qifeng Zhao, Yaxin Dai, Mengna Wu, Yujia Zhai, Le Xu, Xue Gu, Junfen Lin, Chen Wu
{"title":"Evaluating Large Language Models' Potential in Field Epidemiology Investigation Based on Chinese Context- Zhejiang Province, China, 2025.","authors":"Tao Zhang, Qifeng Zhao, Yaxin Dai, Mengna Wu, Yujia Zhai, Le Xu, Xue Gu, Junfen Lin, Chen Wu","doi":"10.46234/ccdcw2025.220","DOIUrl":"https://doi.org/10.46234/ccdcw2025.220","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>Large language models (LLMs) have demonstrated considerable potential in clinical applications. However, their performance in field epidemiology, particularly within Chinese-language contexts, remains largely unexplored.</p><p><strong>What is added by this report?: </strong>This study evaluates six leading LLMs (ChatGPT-o4-mini-high, ChatGPT-4o, DeepSeek-R1, DeepSeek-V3, Qwen3-235B-A22B, and Qwen2.5-Max) using examination questions from the Zhejiang Field Epidemiology Training Program. For multiple-choice questions, all models except DeepSeek-V3 scored below the 75th percentile of junior field epidemiologists, while for case-based questions, LLMs generally outperformed that percentile. However, LLMs demonstrated significant limitations when addressing questions requiring specialized knowledge. Notably, LLMs may generate inaccurate or fabricated references, presenting substantial risks for inexperienced practitioners.</p><p><strong>What are the implications for public health practice?: </strong>LLMs demonstrate promising potential for supporting epidemiological investigations. Nevertheless, current LLMs cannot replace human expertise in field epidemiology. Their practical implementation faces considerable challenges, including ensuring output accuracy and reliability. Future efforts should prioritize optimizing performance through verified knowledge databases and establishing robust regulatory frameworks to enhance their effectiveness in public health applications.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 41","pages":"1296-1301"},"PeriodicalIF":2.9,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12518964/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国疾病预防控制中心周报Pub Date : 2025-10-10DOI: 10.46234/ccdcw2025.221
Zhiping Long, Liebo Zhu, Jian Cai, Hanran Ji, Zhen Ye, Xuguang Shi, Guangming Zhang, Shuying Zhu, Xuelian Zhang, Zhifeng Pang, Kaizhi Bai, Jun Jiang, Jiming Sun
{"title":"The Cluster of Mpox (Clade Ib) Infections - Yiwu City, Zhejiang Province, China, July-August 2025.","authors":"Zhiping Long, Liebo Zhu, Jian Cai, Hanran Ji, Zhen Ye, Xuguang Shi, Guangming Zhang, Shuying Zhu, Xuelian Zhang, Zhifeng Pang, Kaizhi Bai, Jun Jiang, Jiming Sun","doi":"10.46234/ccdcw2025.221","DOIUrl":"https://doi.org/10.46234/ccdcw2025.221","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>Mpox transmission occurs primarily through close skin-to-skin contact, sexual contact, and exposure to contaminated materials; imported cases can establish local transmission clusters in settings characterized by high international mobility.</p><p><strong>What is added by this report?: </strong>This report documents the first identified cluster of mpox virus Clade Ib infections in Yiwu, China, an international trade hub. A total of six laboratory-confirmed cases were identified between July 23-August 6, 2025, including one imported source case from Tanzania and five locally linked secondary cases. Among 43 environmental samples, 27 (62.8%) tested positive for MPXV DNA. Ninety close and general contacts were traced and monitored under 21-day health surveillance, with no additional infections detected. We also report a case with oropharyngeal PCR positivity prior to rash onset, suggesting potential pre-symptomatic viral shedding.</p><p><strong>What are the implications for public health practice?: </strong>Rapid multi-agency collaboration encompassing case identification, isolation protocols, contact tracing, and environmental decontamination proves effective for interrupting transmission in international trade hubs; targeted surveillance and proactive outreach to high-risk social and sexual networks remain essential components of outbreak control.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 41","pages":"1308-1313"},"PeriodicalIF":2.9,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12518958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国疾病预防控制中心周报Pub Date : 2025-10-10DOI: 10.46234/ccdcw2025.219
Ying Liu, Yushan Zhang, Ji Shen, Chi Zhang, Yingchen Sang, Youjiao Wang, Houguang Zhou, Lei Wang, Jie Zhang, Ying Yuan, Shiwei Liu, Hong Shi
{"title":"Spatial Distribution and Clustering Patterns of Cognitive Impairment Among the Older Population - 31 PLADs, China, 2024.","authors":"Ying Liu, Yushan Zhang, Ji Shen, Chi Zhang, Yingchen Sang, Youjiao Wang, Houguang Zhou, Lei Wang, Jie Zhang, Ying Yuan, Shiwei Liu, Hong Shi","doi":"10.46234/ccdcw2025.219","DOIUrl":"https://doi.org/10.46234/ccdcw2025.219","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>As the Chinese population ages, the prevalence of cognitive impairment among older adults continues to increase. Cognitive impairment severely restricts daily activities and creates significant social and economic burdens.</p><p><strong>What is added by this report?: </strong>Using nationally representative data from the China Survey of Aging and Health (CAHS), this study found that the weighted prevalence of subjective cognitive decline and mild cognitive impairment among individuals aged 65 years and older in China was 38.8% and 28.4% in 2024, respectively, and both showed spatial clustering.</p><p><strong>What are the implications for public health practice?: </strong>Through the analysis of spatial distribution patterns and identification of high-risk regions of cognitive impairment, this study provides critical information for developing targeted regional prevention and control interventions.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 41","pages":"1302-1307"},"PeriodicalIF":2.9,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12518956/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国疾病预防控制中心周报Pub Date : 2025-10-03DOI: 10.46234/ccdcw2025.217
Keke Liu, Ran Qin, Huijuan Luo, Huining Kuang, Ranbo E, Chenyu Zhang, Bingjie Sun, Xin Guo
{"title":"Predicting Cycloplegic Spherical Equivalent Refraction Among Children and Adolescents Using Non-cycloplegic Data and Machine Learning - China, 2020-2024.","authors":"Keke Liu, Ran Qin, Huijuan Luo, Huining Kuang, Ranbo E, Chenyu Zhang, Bingjie Sun, Xin Guo","doi":"10.46234/ccdcw2025.217","DOIUrl":"https://doi.org/10.46234/ccdcw2025.217","url":null,"abstract":"<p><strong>Introduction: </strong>Cycloplegic refraction is the gold standard for assessing refractive error in children. However, logistical constraints hinder its implementation in large-scale surveys.</p><p><strong>Methods: </strong>Data obtained from a nationwide ocular health survey conducted in ten provincial-level administrative divisions in China were analyzed (2020-2024). Participants aged 5-18 years underwent standardized non-cycloplegic and cycloplegic autorefraction, axial length (AL), corneal radius (CR), and AL/CR measurements. Random forest and XGBoost models were trained to predict the cycloplegic spherical equivalent (SE) using non-cycloplegic SE, uncorrected visual acuity (UCVA), and biometric parameters. Performance was evaluated using R<sup>2</sup>, root mean square error (RMSE), and Bland-Altman analysis.</p><p><strong>Results: </strong>Both models exhibited strong predictive performance. In the test set, random forest achieved R<sup>2</sup>=0.88 and RMSE=0.55 diopter (D), whereas XGBoost achieved R<sup>2</sup>=0.89 and RMSE=0.54 D. Non-cycloplegic SE, AL/CR ratio, AL, and UCVA were consistently the top predictors. The predicted SE exhibited strong agreement with the cycloplegic SE, with minimal residual bias.</p><p><strong>Conclusion: </strong>Machine learning models incorporating noncycloplegic SE and ocular biometrics accurately estimate cycloplegic SE in children and adolescents, providing a practical alternative for large-scale refractive-error surveillance when cycloplegia is impractical.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 40","pages":"1284-1289"},"PeriodicalIF":2.9,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12518965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association Between Refractive Status and Ocular Biometric Parameters Among Children and Adolescents - 10 PLADs, China, 2020-2024.","authors":"Ruoyi Gao, Huijuan Luo, Yaqing Meng, Liru Wang, Suyun Li, Bingjie Sun, Xin Guo","doi":"10.46234/ccdcw2025.214","DOIUrl":"https://doi.org/10.46234/ccdcw2025.214","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>Myopia prevalence among Chinese students remains persistently high, with axial length and the axial length-to-corneal radius ratio demonstrating significant associations with refractive status in children and adolescents.</p><p><strong>What is added by this report?: </strong>This investigation employed cycloplegic optometry to assess refractive errors across children and adolescents in 10 provincial-level administrative divisions, utilizing axial length (AL) and axial length-to-corneal radius ratio (AL/CR) as predictive indicators of refractive status.</p><p><strong>What are the implications for public health practice?: </strong>The AL/CR ratio demonstrates superior predictive accuracy for myopia compared to AL alone and can effectively identify at-risk children during early developmental stages. Incorporating routine monitoring of AL and AL/CR into school health programs can enhance early detection capabilities and support targeted myopia management strategies.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 40","pages":"1267-1271"},"PeriodicalIF":2.9,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12518955/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国疾病预防控制中心周报Pub Date : 2025-10-03DOI: 10.46234/ccdcw2025.215
Huijuan Luo, Ruoyi Gao, Ting Li, Ming Wu, Yabin Qu, Yaqing Meng, Bingjie Sun, Ran Qin, Xin Guo
{"title":"Current Status of Hyperopic Reserve Among Children and Adolescents - 10 PLADs, China, 2020-2024.","authors":"Huijuan Luo, Ruoyi Gao, Ting Li, Ming Wu, Yabin Qu, Yaqing Meng, Bingjie Sun, Ran Qin, Xin Guo","doi":"10.46234/ccdcw2025.215","DOIUrl":"https://doi.org/10.46234/ccdcw2025.215","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>China exhibits a high prevalence of myopia; however, comprehensive national data based on cycloplegic refraction to assess the current status of hyperopic reserve in children and adolescents remains unavailable.</p><p><strong>What is added by this report?: </strong>This study describes different percentiles of spherical equivalent (SE) after cycloplegic refraction for children and adolescents aged 5-18 years across 10 provincial-level administrative divisions (PLADs) and cities in China. SE values declined progressively with age in both males and females, with females demonstrating significantly lower median SE values than males beginning at age 10.</p><p><strong>What are the implications for public health practice?: </strong>Hyperopic reserve requires systematic monitoring, particularly among females approaching puberty and younger children. Early surveillance by relevant departments is strongly recommended to support comprehensive myopia prevention and control strategies.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 40","pages":"1272-1276"},"PeriodicalIF":2.9,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12518971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国疾病预防控制中心周报Pub Date : 2025-10-03DOI: 10.46234/ccdcw2025.216
Yuwei Zhang, Huijuan Luo, Shuaixing Song, Ran Qin, Yanhua Chen, Ming Wu, Liru Wang, Ciyong Lu, Xin Guo
{"title":"Regional Heterogeneity in Screen Time and Usage Habits Associated with Insufficient Hyperopic Reserve in Schoolchildren - 9 PLADs, China, 2020-2024.","authors":"Yuwei Zhang, Huijuan Luo, Shuaixing Song, Ran Qin, Yanhua Chen, Ming Wu, Liru Wang, Ciyong Lu, Xin Guo","doi":"10.46234/ccdcw2025.216","DOIUrl":"https://doi.org/10.46234/ccdcw2025.216","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>Insufficient hyperopic reserve serves as a preclinical indicator of myopia development and is influenced by socioeconomic factors and behavioral patterns. However, region-specific risk profiles remain inadequately characterized.</p><p><strong>What is added by this report?: </strong>This nationwide investigation demonstrates substantial regional heterogeneity in myopia risk factors. Children residing in low-gross domestic product (GDP) regions exhibit significantly stronger associations between screen time usage and poor screen habits with insufficient hyperopic reserve. This relationship is most pronounced among girls in low-GDP areas.</p><p><strong>What are the implications for public health practice?: </strong>Public health interventions should prioritize targeted screen use guidance for children, particularly girls in socioeconomically disadvantaged regions, to effectively protect visual health and prevent myopia progression.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 40","pages":"1277-1283"},"PeriodicalIF":2.9,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12518968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国疾病预防控制中心周报Pub Date : 2025-10-03DOI: 10.46234/ccdcw2025.213
Xin Guo
{"title":"The Significance of Hyperopic Reserve Monitoring and Its Value for Myopia Prevention and Control.","authors":"Xin Guo","doi":"10.46234/ccdcw2025.213","DOIUrl":"https://doi.org/10.46234/ccdcw2025.213","url":null,"abstract":"","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 40","pages":"1263-1266"},"PeriodicalIF":2.9,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12518961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中国疾病预防控制中心周报Pub Date : 2025-09-26DOI: 10.46234/ccdcw2025.212
Qingjun Chen, Wenwu Yin, Zhenggang Zhu, Chuanlin Wang
{"title":"The Clinical Advantages of Anti-Rabies Monoclonal Antibodies in Post-Exposure Prophylaxis - Worldwide, 2016-2025.","authors":"Qingjun Chen, Wenwu Yin, Zhenggang Zhu, Chuanlin Wang","doi":"10.46234/ccdcw2025.212","DOIUrl":"https://doi.org/10.46234/ccdcw2025.212","url":null,"abstract":"<p><p>Post-exposure prophylaxis (PEP) represents the critical intervention for preventing rabies and comprises three essential components: thorough wound cleansing, vaccination, and administration of rabies immunoglobulin (RIG) or monoclonal antibodies (mAbs) for category III exposures. The World Health Organization (WHO) endorses the use of mAb cocktails as an effective replacement for RIG in PEP protocols. Since 2016, four anti-rabies monoclonal antibodies (RmAbs) have received clinical approval for use in India and China. This article provides an overview of the current research status of RmAb. By reviewing clinical studies related to RmAb, it highlights the clinical advantages of RmAb over HRIG in terms of efficacy, accessibility, safety, acceptability, and clinical application in special populations. Additionally, it explores the future clinical prospects of RmAb, including their use in extremely high-risk cases, their impact on circulating antibodies, and their potential role in rabies treatment.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 39","pages":"1258-1262"},"PeriodicalIF":2.9,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12518957/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}