Analysis on Cross-Species Transmission of Human-Suidae Zoonotic Viruses - Global, 1882-2022.

Abstract

What is already known about this topic?: Zoonotic diseases, particularly those caused by viruses capable of cross-species transmission, represent a significant threat to global public health security. Suidae have been recognized as critical intermediate hosts in numerous zoonotic virus transmission pathways. However, previous research has predominantly concentrated on individual viruses or isolated outbreaks, thereby constraining our comprehensive understanding of broader cross-species transmission patterns and risk factors.

What is added by this report?: This study systematically investigates cross-species transmission patterns of Suidae-related zoonotic viruses using comprehensive data from public databases, including the National Center for Biotechnology Information (NCBI). Through the integration of viral characteristics, host factors, environmental variables, and anthropogenic influences, we constructed predictive models to identify transmission hotspots and assess potential cross-species events. The research provides a comprehensive, data-driven framework for understanding zoonotic virus dynamics on a global scale.

What are the implications for public health practice?: These findings provide robust theoretical foundations and practical tools for early warning systems and targeted prevention strategies for zoonotic diseases, particularly those involving Suidae as intermediate hosts. This research advances the One Health approach by elucidating the interconnected roles of humans, animals, and environmental factors in viral transmission dynamics, thereby informing evidence-based global surveillance and response strategies for pandemic preparedness.