中国疾病预防控制中心周报最新文献

{"title":"Implications of International and Domestic Strategies, Policies, and Practices for Obesity Prevention and Control - China, 2023.","authors":"Weixi Deng, Wenqi Xia, Xiaomin Sun, Xinyi Zheng, Sichen Zhang, Zhaozhang Sun, Wen Peng, Bo Gou, Youfa Wang, Jianduan Zhang","doi":"10.46234/ccdcw2025.192","DOIUrl":"10.46234/ccdcw2025.192","url":null,"abstract":"<p><strong>Introduction: </strong>Obesity has emerged as a critical public health challenge in China, with prevalence rates rising steadily across all age groups and threatening both long-term health outcomes and economic sustainability. This study examines China's current obesity prevention and control landscape, comparing it with international practices to provide evidence-based recommendations for strengthening national strategies.</p><p><strong>Methods: </strong>Between July and October 2023, we conducted a comprehensive literature review and engaged 19 experts (9 from China; 10 from the United States (US), Japan, the United Kingdom (UK), and Spain) through purposive, criterion-based sampling. We collected data using a semi-structured questionnaire covering personal information, obesity-related policies and service status, and recommendations for China. Quantitative data underwent descriptive analysis, while qualitative data were examined using thematic analysis.</p><p><strong>Results: </strong>Experts identified persistent barriers in China's obesity control efforts, including fragmented policies, insufficient public awareness, suboptimal service quality, and limited healthcare facilities. Compared with high-income countries, China's approach lacks robust regulatory frameworks and effective multisectoral coordination mechanisms.</p><p><strong>Conclusions: </strong>These findings underscore the urgent need for China to strengthen evidence-based, integrated approaches to obesity prevention and management. Adapting successful international experiences to local contexts will be essential for enhancing national obesity control efforts and advancing the <i>Healthy China</i> initiative goals.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 35","pages":"1144-1150"},"PeriodicalIF":2.9,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12421418/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obesity Control and Cancer Prevention in China: Insights from the Weight Management Year.","authors":"Ci Song, Hongbing Shen","doi":"10.46234/ccdcw2025.189","DOIUrl":"10.46234/ccdcw2025.189","url":null,"abstract":"<p><p>Obesity has emerged as a critical public health challenge worldwide and in China, substantially contributing to the burden of chronic diseases, including cancer. In response, China launched the \"Weight Management Year\" initiative in 2024, representing a strategic shift toward upstream interventions in chronic disease control. This perspective examines the essential role of obesity control in cancer prevention across the complete prevention continuum - primordial (zero-level), primary, secondary, and tertiary prevention. The initiative presents a unique opportunity to integrate weight management strategies into health promotion, early risk identification, screening programs, and post-diagnosis rehabilitation. It emphasizes incorporating obesity-related cancer prevention into routine healthcare through digital platforms, multidisciplinary collaboration, and population-wide education campaigns. However, significant challenges persist, including limited public awareness of obesity's carcinogenic risks, insufficient integration between clinical and public health systems, and inadequate multi-sectoral cooperation. Moving forward, cancer prevention in China must transition from a reactive, screening-focused model to a proactive, life-course approach centered on behavioral and lifestyle interventions. Strengthening risk communication, institutionalizing weight management across all prevention levels, and fostering cross-sectoral collaboration are essential for building a sustainable, population-wide cancer prevention framework.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 35","pages":"1127-1131"},"PeriodicalIF":2.9,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12421416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal Trajectories of Adiposity Indicators and Cancer Risk Over 14 Years: Evidence from Repeated Health Check-Ups of 10 Times or More - China, 2010-2023.","authors":"Le Wang, Tingting Fu, Yong Yang, Yifei Lin, Jin Huang","doi":"10.46234/ccdcw2025.191","DOIUrl":"10.46234/ccdcw2025.191","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>Central obesity is a recognized risk factor for several types of cancers. However, most supporting evidence originates from Western populations and relies on single adiposity measurements, with limited longitudinal data available from China.</p><p><strong>What is added by this report?: </strong>Drawing on data from more than 25,000 Chinese adults who each underwent 10 or more health check-ups over 14 years, this study demonstrated that waist-related indicators - particularly Body Mass Index -adjusted waist circumference (WCadjBMI) and waist-to-hip ratio (WHRadjBMI) - and their inverted U-shaped trajectories are more strongly associated with cancer risk than BMI alone, especially in men and adults aged 50 years and above.</p><p><strong>What are the implications for public health practice?: </strong>Tracking changes in waist-related fat measures over time may help identify cancer risk earlier than BMI monitoring alone. Integrating central obesity measures into routine screening could improve targeted cancer prevention, particularly for the older and male populations, and advance the goals of Healthy China 2030.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 35","pages":"1138-1143"},"PeriodicalIF":2.9,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12421424/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Auxiliary Diagnostic Value of the Interferon Gamma-Induced Protein 10 mRNA Release Assay for Tuberculosis in People Living with HIV/AIDS - Beijing Municipality, China, 2022-2024.","authors":"Hongxia Yan, Hongfei Duan, Xiaoxu Han, Jin Sun, Qingtao Liang, Yan Zhao, Zhenglai Ma, Ning Ding, Meixin Ren, Taiyi Jiang, Tong Zhang, Bin Su","doi":"10.46234/ccdcw2025.186","DOIUrl":"10.46234/ccdcw2025.186","url":null,"abstract":"<p><strong>Introduction: </strong>Diagnosing tuberculosis (TB) in HIV-infected individuals presents significant challenges due to difficulties in obtaining specimens containing adequate quantities of <i>Mycobacterium tuberculosis</i> (<i>Mtb</i>). This study aimed to evaluate the diagnostic performance of the <i>IP-10</i> mRNA assay independently and in combination with established diagnostic tests for <i>Mtb</i> detection.</p><p><strong>Methods: </strong>The study cohort comprised 111 HIV-infected individuals who presented with TB at Beijing Youan Hospital from 2022 to 2024. Participants were categorized into confirmed TB, probable TB, or non-TB groups according to the diagnostic criteria for tuberculosis (WS288-2017). The performance of the <i>IP-10</i> mRNA release assay was evaluated by the STARD guidelines on blood samples collected after enrollment.</p><p><strong>Results: </strong>The <i>IP-10</i> mRNA release assay demonstrated significantly higher sensitivity than interferon-γ release assays (IGRAs) and culture methods for confirming pulmonary tuberculosis (PTB) diagnosis while maintaining comparable specificity. Receiver operating characteristic (ROC) analysis revealed that the diagnostic performance of the <i>IP-10</i> mRNA release assay used in parallel with Xpert MTB/RIF significantly exceeded that of the <i>IP-10</i> mRNA release assay alone (0.731 <i>vs</i>. 0.687, <i>P</i>=0.02). Among HIV-infected individuals, the <i>IP-10</i> mRNA release assay showed superior performance compared to IGRAs for diagnosing extrapulmonary tuberculosis.</p><p><strong>Conclusions: </strong>The <i>IP-10</i> mRNA release assay exhibited excellent diagnostic performance and demonstrates substantial potential as an auxiliary tool for diagnosing TB in HIV-infected individuals. The combined application of IP-10<i>.</i>TB and Xpert MTB/RIF further enhance diagnostic efficacy.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 34","pages":"1106-1113"},"PeriodicalIF":2.9,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12421425/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Outbreak of Dermatitis Caused by <i>Redoa leucoscela</i> Larvae in A Scenic Area - Tongren City, Guizhou Province, China, July-August 2024.","authors":"Mei Xiao, Dafei Ren, Leting Ning, Qi Yang, Tian Fei","doi":"10.46234/ccdcw2025.188","DOIUrl":"10.46234/ccdcw2025.188","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong><i>Redoa leucoscela</i> (<i>R. leucoscela)</i> Collenette (Lepidoptera: Erebidae), releases urticating setae during larval molting. These setae disperse through aquatic and aerial pathways and can trigger allergic reactions upon dermal contact. Clinical manifestations include pruritic dermatitis with stinging sensations and papular lesions; untreated cases may progress to systemic reactions or secondary infections.</p><p><strong>What is added by this report?: </strong>Between July 10 and August 16, 2024, a dermatitis outbreak caused by <i>R. leucoscela</i> occurred in Y Village, Tongren City, Guizhou Province. A total of 32 cases were identified, including 30 residents and 2 tourists. This report provides the first epidemiological evidence linking <i>R. leucoscela</i> larvae to dermatitis outbreaks through rigorous case-control methodology.</p><p><strong>What are the implications for public health practice?: </strong>During peak <i>R. leucoscela</i> larvae infestation periods, local authorities must implement integrated dermatitis surveillance and larval eradication programs, coupled with prominent warning signage in high-risk zones (riversides, swimming areas) advising against water contact and minimizing exposure to <i>P. stenoptera</i> tree foliage to prevent outbreak recurrence. Concurrently, health promotion campaigns must prioritize eco-awareness education for tourism stakeholders and the public, advocating for eco-conscious tourism behaviors to minimize anthropogenic habitat disruption, thereby achieving sustainable tourism-conservation synergy.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 34","pages":"1121-1126"},"PeriodicalIF":2.9,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12421417/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Intercultural Communication Competence for China Field Epidemiology Training Program (CFETP) Trainees - China, 2025.","authors":"Jing Sun, Yuansheng Fang, Jiewen Wu, Hanran Ji, Mingfan Pang, Lili Wang, Xinping Yang, Na Li, Daijun Teng, Yating Sun, Xiaopeng Qi","doi":"10.46234/ccdcw2025.187","DOIUrl":"10.46234/ccdcw2025.187","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>Trainees in the China Field Epidemiology Training Program (CFETP) constitute a vital workforce in addressing global public health emergencies. Developing intercultural communication competence is essential for their future participation in international public health efforts. However, within China's existing public health training system, this aspect has not yet received adequate attention or been systematically strengthened.</p><p><strong>What is added by this report?: </strong>This study is the first to evaluate and investigate the intercultural communication competence of domestic CFETP trainees. There are 77 trainees that demonstrated strong cognitive (Score rates: 86.57%) and emotional (87.22%) competencies. However, behavioral (79.42%) competence, particularly language proficiency, can be improved. Further analysis indicated that international experience, duration of time spent abroad, and foreign language proficiency had a significant impact on their intercultural communication competence.</p><p><strong>What are the implications for public health practice?: </strong>This study examined the current state of intercultural communication competence among public health professionals and the factors influencing it. It highlights the key obstacles and practical challenges trainees face in intercultural communication while providing essential data to inform the development of targeted strategies for improving competence and refining training programs.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 34","pages":"1114-1120"},"PeriodicalIF":2.9,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12421420/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Service Utilization and Medication Adherence Among Attendees of HIV Nonoccupational Post-Exposure Prophylaxis Clinics - China, 2022-2024.","authors":"Mengnan Tan, Jie Xu, Wei Dong","doi":"10.46234/ccdcw2025.185","DOIUrl":"10.46234/ccdcw2025.185","url":null,"abstract":"<p><strong>Introduction: </strong>Human Immunodeficiency Virus (HIV) nonoccupational post-exposure prophylaxis (nPEP) clinics are specialized healthcare facilities that provide urgent medical interventions to individuals with potential high-risk HIV exposures. This study analyzed utilization patterns of HIV nPEP services in China and examined factors associated with medication adherence among consultees, providing evidence to inform further implementation and optimization of HIV nPEP interventions.</p><p><strong>Methods: </strong>We analyzed nPEP case data collected from the national nPEP data information system between November 1, 2022, and November 1, 2024, using SPSS 29.0 software. Chi-square tests were applied to analyze characteristics of nPEP consultees, and logistic regression models were used to identify factors influencing medication adherence and follow-up compliance among those who initiated treatment.</p><p><strong>Results: </strong>As of November 1, 2024, 924 nPEP clinics nationwide received 54,108 consultees, with 53,405 (98.70%) initiating medication. Most individuals seeking services were male (88.63%), classified as high-risk (83.11%), and heterosexual with multiple partners (67.66%). The \"BIC/FTC/TAF\" regimen was selected by 63.07% of recipients. Nearly all users (99.03%) completed medication evaluation within 72 hours post-exposure. Among medication users, 60.34% (30,650) adhered to the full 28-day regimen, and 60.10% (30,509) completed either one-month or three-month follow-ups. Multivariate logistic regression analysis identified gender, exposure risk assessment results, exposure population classification, individual preferences, and medication regimen as significant factors influencing both 28-day medication adherence and follow-up compliance (<i>P</i><0.05).</p><p><strong>Conclusions: </strong>nPEP clinic consultees in China are predominantly young male heterosexual individuals with multiple sexual partners, with most selecting the Biktarvy regimen. However, both current 28-day medication adherence and follow-up compliance rates remain suboptimal. High-risk men and those receiving the Biktarvy regimen demonstrate superior medication adherence and follow-up compliance compared to other groups. Further research is needed to develop targeted interventions to improve medication adherence and follow-up rates among nPEP recipients. Enhancing adherence and follow-up should be prioritized in future interventions, supported by continuous monitoring to inform timely intervention strategy adjustments.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 34","pages":"1099-1105"},"PeriodicalIF":2.9,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12421423/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Viral Load Dynamics of Chikungunya Virus in Human Specimens - Foshan City, Guangdong Province, China, 2025.","authors":"Shuichun Wan, Xin Zhang, Xiao Cong, Yi Liu, Shen Huang, Mingyi Zhou, Changyun Sun, Xiaofang Peng, Huan Zhang, Yihai Yu, Baisheng Li, Jianfeng He","doi":"10.46234/ccdcw2025.182","DOIUrl":"10.46234/ccdcw2025.182","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>Chikungunya virus (CHIKV) represents an Aedes-borne alphavirus that causes fever, rash, and severe arthralgia. Outbreaks have expanded across 119 countries, with sporadic imported cases documented in China. While serum has been regarded as the optimal diagnostic specimen, comprehensive data comparing multiple specimen types across all infection phases have remained lacking.</p><p><strong>What is added by this report?: </strong>Using 1,156 samples from the 2025 Foshan outbreak, we quantified CHIKV RNA levels from 6 days before to 12 days after symptom onset. Serum consistently yielded the highest viral loads, while saliva, urine, and throat swabs demonstrated inferior performance. Viral RNA detection was achievable as early as 1 day before symptom onset. Days 0-7 post-symptom onset constitute the phase of explosive viral replication, representing the optimal timeframe for specimen collection to minimize false-negative results. From Day 8 onward, antibody IgG testing should be incorporated to prevent diagnostic gaps.</p><p><strong>What are the implications for public health practice?: </strong>Pre-symptomatic polymerase chain reaction (PCR) testing of serum (day-1) enables interception of imported cases at ports of entry; days 0-7 represent the optimal clinical sampling window to minimize false negatives. After day 8, antibody testing must supplement molecular diagnostics. This systematic analysis of CHIKV viral-load kinetics provides critical evidence for calibrating quarantine duration, optimizing contact-tracing intensity, and allocating resources effectively, thereby reducing community transmission risk substantially.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 33","pages":"1067-1072"},"PeriodicalIF":2.9,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12365650/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144980431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological Characteristics of Tuberculosis Among Interprovincial Migrants - China, 2019-2023.","authors":"Da Xu, Xue Li, Feifei Tian, Zhezhe Cui, Wei Chen","doi":"10.46234/ccdcw2025.180","DOIUrl":"10.46234/ccdcw2025.180","url":null,"abstract":"<p><strong>Introduction: </strong>Tuberculosis (TB) represents one of China's most significant infectious disease, with inter-provincial population migration posing a challenge to controlling its spread. This study examined TB cases among inter-provincial migrants across China from 2019 to 2023.</p><p><strong>Methods: </strong>TB surveillance data were extracted from China's Tuberculosis Information Management System and analyzed using R software (version 4.4.0). After information desensitization, the relevant information of TB patients with differing current and permanent address codes was extracted.</p><p><strong>Results: </strong>Between 2019 and 2023, we identified 123,945 TB cases among inter-provincial migrants, representing 4.03% (123,945/3,077,951) of all reported TB cases. The primary destination provincial-level administrative divisions (PLADs) for TB patients were Guangdong (48,183 cases, 38.9%), Zhejiang (27,383 cases, 22.1%), Fujian (8,582 cases, 6.9%), Beijing (7,959 cases, 6.4%), and Shanghai (7,403 cases, 5.9%), collectively accounting for 80.3% of all inter-provincial migrant TB cases. The PLADs with the highest outflow of TB migrants were Sichuan (15,155 cases, 12.23%), Hunan (14,707 cases, 11.87%), Guizhou (13,927 cases, 11.24%), Jiangxi (8,892 cases, 7.17%), and Hubei (8,441 cases, 6.81%). Among these migrant cases, 66.2% were male, 93.0% were newly diagnosed, 2.4% exhibited drug resistance. The proportion of individuals aged 45-64, aged ≥65 and re-treated exhibited a significant annual increase (<i>P</i><0.001). The overall successful treatment rate was 89.5%, while 5.3% experienced adverse treatment outcomes. Throughout the study period, the lowest proportion of TB cases among inter-provincial migrants occurred in February.</p><p><strong>Conclusion: </strong>From 2019 to 2023, the characteristics of TB among inter-PLADs migrant patients have undergone certain changes. The migration of TB primarily flows from economically weaker regions to more developed areas, with the main destination PLADs relatively stable. Effective TB control among inter-PLADs migrants requires targeted screening programs focusing on individuals from major source and destination PLADs. Tailored strategies should be developed based on the migration patterns of different PLADs.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 33","pages":"1079-1086"},"PeriodicalIF":2.9,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12365652/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144980412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Outbreak of Isoniazid-Resistant Tuberculosis in a School Originating from Household Transmission - Guigang City, Guangxi Zhuang Autonomous Region, China, November 2024.","authors":"Da Xu, Xiaoyan Liang, Lingyun Zhou, Wei Chen, Jing Ye, Juan Li, Weihua Yao, Jinhui Zhu, Zhezhe Cui","doi":"10.46234/ccdcw2025.183","DOIUrl":"10.46234/ccdcw2025.183","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>Tuberculosis (TB) represents one of the world's most significant infectious diseases, caused by <i>Mycobacterium tuberculosis</i> (<i>M. tuberculosis</i>). The pathogen spreads readily among students due to crowded environments and prolonged close contact during school activities.</p><p><strong>What is added by this report?: </strong>This outbreak investigation identified 18 TB cases (15 students, 1 teacher, and 2 staff members), including 5 cases with isoniazid-resistant TB. Sixteen pulmonary TB cases demonstrated clear epidemiological linkage, indicating a clustered outbreak spanning multiple households, school grades, and both junior and senior high schools.</p><p><strong>What are the implications for public health practice?: </strong>This outbreak underscores the critical importance of comprehensive household contact screening. When tuberculosis emerges within a family unit, school contacts - particularly students and teachers - require immediate and thorough screening. Additionally, the outbreak reveals significant gaps in the effectiveness and quality of entrance physical examinations that demand urgent improvement.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 33","pages":"1087-1092"},"PeriodicalIF":2.9,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12365653/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144980370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}