中华普通外科杂志最新文献_第3页

Roux-en-Y hilar-jejunum anastomosis for biliary tract reconstruction after radical resection of hilar cholangiocarcinoma Roux-en-Y肝门-空肠吻合术在肝门胆管癌根治术后胆道重建中的应用

中华普通外科杂志 Pub Date : 2020-02-25 DOI: 10.3760/CMA.J.ISSN.1007-631X.2020.02.001

Zhedong Zhang, Dafang Zhang, Weihua Zhu, Jiye Zhu, Shu Li, X. Leng

{"title":"Roux-en-Y hilar-jejunum anastomosis for biliary tract reconstruction after radical resection of hilar cholangiocarcinoma","authors":"Zhedong Zhang, Dafang Zhang, Weihua Zhu, Jiye Zhu, Shu Li, X. Leng","doi":"10.3760/CMA.J.ISSN.1007-631X.2020.02.001","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-631X.2020.02.001","url":null,"abstract":"Objective \u0000To investigate the effect of Roux-en-Y hilar-jejunum anastomosis in surgical resection of hilar cholangiocarcinoma. \u0000 \u0000 \u0000Methods \u0000The clinical data of 31 patients with hilar cholangiocarcinoma admitted from Feb 2009 to Feb 2017 who underwent Roux-en-Y hilar-jejunum anastomosis after resection were retrospectively analyzed. \u0000 \u0000 \u0000Results \u0000According to Bismuth-Corlette classification there were 6 cases of IIIa, 6 cases of IIIb and 19 cases of type IV. These patients all successfully underwent Roux-en-Y hilar-jejunum anastomosis, with intraoperative blood loss of 50-4000 ml (on average of 1146±1082 ml). The average operation time was (346±118) min, and the average hilar-jejunum anastomosis time was (35±13) min. The average postoperative hospital stay was (20±11) days. There were 25 cases of R0 resection(80.6%). The postoperative complication rate was 25.8% (8/31). The overall median survival time was 21 months, and the 1-, 3-, and 5-year survival rates were 68.8%, 14.6%, and 3.6%, respectively. During the follow-up period, 7 cases of reflux cholangitis, 5 cases of biliary anastomotic stenosis, and 1 case of adhesive intestinal obstruction were found. \u0000 \u0000 \u0000Conclusion \u0000The hilar-jejunum anastomosis is simple, safe, widely applicable prcedure, which is easy to perform. \u0000 \u0000 \u0000Key words: \u0000Bile duct neoplasms; Roux-en-Y hilar-jejunum anastomosis; Postoperative complications","PeriodicalId":66425,"journal":{"name":"中华普通外科杂志","volume":"35 1","pages":"89-91"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44123006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prognostic value of the fibrinogen to albumin ratio in patients with gallbladder carcinoma 纤维蛋白原与白蛋白比值对胆囊癌患者的预后价值

中华普通外科杂志 Pub Date : 2020-02-25 DOI: 10.3760/CMA.J.ISSN.1007-631X.2020.00.015

Rui Li, Shibo Song, Qiang Li, Xiaolei Shi, Zhen Sun, Xiu-wen He, Zhe Li, Jinghai Song

{"title":"Prognostic value of the fibrinogen to albumin ratio in patients with gallbladder carcinoma","authors":"Rui Li, Shibo Song, Qiang Li, Xiaolei Shi, Zhen Sun, Xiu-wen He, Zhe Li, Jinghai Song","doi":"10.3760/CMA.J.ISSN.1007-631X.2020.00.015","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-631X.2020.00.015","url":null,"abstract":"Objective \u0000To investigate the prognostic value of preoperative fibrinogen and albumin ratio (FAR) in patients with gallbladder carcinoma. \u0000 \u0000 \u0000Methods \u0000The clinicopathological data of 100 patients with gallbladder carcinoma who underwent radical surgery at Beijing Hospital from Feb 2007 to Feb 2019 were retrospectively analyzed. The receiver operating characteristic (ROC) curve was drawn to determine the optimal cut-off value of FAR, and the prognostic factors were evaluated by Kaplan-Meier method, univariate and multivariate analysis. \u0000 \u0000 \u0000Results \u0000The optimal cut-off value of preoperative FAR for postoperative overall survival was 0.08. FAR was significantly associated with preoperative total bilirubin(TBil)levels, tumor differentiation, T stage, TNM stage, resection margin status, and preoperative CA199 levels (all P<0.05). Multivariate analysis indicated that TNM staging (HR=3.562, 95% CI: 1.075-11.798, P=0.038) and FAR (HR=2.482, 95% CI: 1.263-4.875, P=0.008) were independent prognostic factors in patients with gallbladder carcinoma who underwent radical surgery. \u0000 \u0000 \u0000Conclusion \u0000Preoperative FAR is closely related to the prognosis of patients with gallbladder carcinoma and might be useful for the evaluation of prognosis of patients with gallbladder carcinoma. \u0000 \u0000 \u0000Key words: \u0000gallbladder carcinoma; fibrinogen; albumin; prognosis","PeriodicalId":66425,"journal":{"name":"中华普通外科杂志","volume":"35 1","pages":"142-145"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41376221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical characteristics and prognosis of 26 cases of combined hepatocellular carcinoma and cholangiocarcinoma 肝细胞癌合并胆管癌26例临床特点及预后分析

中华普通外科杂志 Pub Date : 2020-02-25 DOI: 10.3760/CMA.J.ISSN.1007-631X.2020.02.011

Linhong Wu, Peng-ji Gao, Jie Gao, Zhao Li, Jiye Zhu, X. Leng

{"title":"Clinical characteristics and prognosis of 26 cases of combined hepatocellular carcinoma and cholangiocarcinoma","authors":"Linhong Wu, Peng-ji Gao, Jie Gao, Zhao Li, Jiye Zhu, X. Leng","doi":"10.3760/CMA.J.ISSN.1007-631X.2020.02.011","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-631X.2020.02.011","url":null,"abstract":"Objective \u0000To investigate the clinical manifestations, imaging features and prognosis of mixed liver cancer. \u0000 \u0000 \u0000Methods \u0000The clinical and pathological data of 26 patients with combined hepatocellular carcinoma and cholangiocarcinoma (cHCC-CC) pathologically diagnosed after liver resection were retrospectively analyzed, and the relevant factors affecting the prognosis were statistically analyzed. \u0000 \u0000 \u0000Results \u0000Of the 26 cHCC-CC patients, 19 were on background of chronic viral hepatitis, including 17 chronic viral hepatitis B and 2 chronic viral hepatitis C. There were 18 cases having AFP≥20ng/ml, 9 cases were with carbohydrate antigen 199 (CA199)≥37U/ml, and 5 cases with carcinoembryonic antigen (CEA)≥5ng/ml. The 1 -, 3 -, and 5-year postoperative survival rates were 68.8%, 34.4%, and 17.4%. Multivariate analysis showed that serum CA199≥37U/ ml(χ2=5.687, P=0.019) was an independent risk factor for patients′ survival. \u0000 \u0000 \u0000Conclusion \u0000Most cHCC-CC is found in association with chronic viral hepatitis. Serum CA199≥37U/ml is an independent risk factor affecting patients survival. \u0000 \u0000 \u0000Key words: \u0000Carcinoma, hepatocellular; Prognosis; Survival analysis","PeriodicalId":66425,"journal":{"name":"中华普通外科杂志","volume":"35 1","pages":"128-130"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41482408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Expression of FNDC5 in liver cancer tissues and its relationship with clinical parameters FNDC5在癌症组织中的表达及其与临床参数的关系

中华普通外科杂志 Pub Date : 2020-02-25 DOI: 10.3760/CMA.J.ISSN.1007-631X.2020.02.016

N. Tang, F. Huang, Deguo Zhang, Guangjun Shi

{"title":"Expression of FNDC5 in liver cancer tissues and its relationship with clinical parameters","authors":"N. Tang, F. Huang, Deguo Zhang, Guangjun Shi","doi":"10.3760/CMA.J.ISSN.1007-631X.2020.02.016","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-631X.2020.02.016","url":null,"abstract":"Objective \u0000To investigate the expression of FNDC5 in hepatocellular carcinoma (HCC) and its relationship with clinicopathological characteristics and prognosis of HCC patients. \u0000 \u0000 \u0000Methods \u0000Immunohistochemistry and qRT-PCR were used to detect the expression of FNDC5 in HCC tissues, and the relationship between its expression and clinicopathological parameters and prognosis. \u0000 \u0000 \u0000Results \u0000FNDC5 was mainly expressed in the cytoplasm of HCC cells, weakly expressed in the nucleus. Among the 30 liver cancer tissues, FNDC5 was weakly positive in 5, positive in 19, and strongly positive in 6 cases. QRT-PCR assay showed that FNDC5 was highly expressed in HCC tissues with vascular invasion.The incidence of vascular invasion in the high-expression of FNDC5 was 30% (9/30), which was significantly higher than that of the FNDC5 low-expression group[6.7% (2/30), ]and the difference was significant (χ2 =15.026, P 0.05). \u0000 \u0000 \u0000Conclusion \u0000FNDC5 level in the liver cancer tissues is closely related to the occurrence of vascular invasion. \u0000 \u0000 \u0000Key words: \u0000Carcinoma, hepatocellular; Neoplasm invasiveness","PeriodicalId":66425,"journal":{"name":"中华普通外科杂志","volume":"35 1","pages":"146-149"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47222657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical analysis on 13 cases of hepatic lymphoepithelioma-like carcinoma 肝淋巴上皮瘤样癌13例临床分析

中华普通外科杂志 Pub Date : 2020-02-25 DOI: 10.3760/CMA.J.ISSN.1007-631X.2020.02.012

Jianjun Xu, Xiang Cheng, Xingdi Zhou, Yang Gao, Weimin Wang, Q. Zheng, Shao-bo Hu

{"title":"Clinical analysis on 13 cases of hepatic lymphoepithelioma-like carcinoma","authors":"Jianjun Xu, Xiang Cheng, Xingdi Zhou, Yang Gao, Weimin Wang, Q. Zheng, Shao-bo Hu","doi":"10.3760/CMA.J.ISSN.1007-631X.2020.02.012","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-631X.2020.02.012","url":null,"abstract":"Objective \u0000To summarize the clinical characteristics of hepatic lymphoepithelioma-like carcinoma, and to explore the diagnosis and treatment strategies of hepatic lymphoepithelioma-like carcinoma. \u0000 \u0000 \u0000Methods \u0000A retrospectively analysis on 13 patients with liver lymphoepithelioma-like carcinoma in Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, between March 2005 and May 2019 were carried out. \u0000 \u0000 \u0000Results \u00008 cases were male , 5 were female, median age was 45 years (27 to 68 y). There were 8 cases of intrahepatic cholangiocytic lymphoepithelioma-like carcinoma, 4 cases of hepatocytic lymphoepithelioma-like carcinoma, and 1 case of mixed hepatocytic and cholangiocytic lymphoepithelioma-like carcinoma . All patients received partial hepatectomy and postoperative comprehensive treatment. The patients were followed from 6 months to 7 years. Only one patient died, and the other patients were all in a tumor-free state. \u0000 \u0000 \u0000Conclusion \u0000Primary hepatic lymphoepithelioma-like carcinoma is a rare liver cancer. It is confirmed mainly by pathological examination and immunohistochemistry. With surgery as the main treatment, prognosis is usually fair. \u0000 \u0000 \u0000Key words: \u0000Liver neoplasms; Hepatectomy","PeriodicalId":66425,"journal":{"name":"中华普通外科杂志","volume":"35 1","pages":"131-134"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47860162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnosis and treatment of rare types of hepatic benign space occupying lesions 罕见型肝脏良性占位性病变的诊断与治疗

中华普通外科杂志 Pub Date : 2020-02-25 DOI: 10.3760/CMA.J.ISSN.1007-631X.2020.02.003

Gang Wang, Tao Li, X. Leng, Jiye Zhu

{"title":"Diagnosis and treatment of rare types of hepatic benign space occupying lesions","authors":"Gang Wang, Tao Li, X. Leng, Jiye Zhu","doi":"10.3760/CMA.J.ISSN.1007-631X.2020.02.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-631X.2020.02.003","url":null,"abstract":"Objective \u0000To summarize the experience of diagnosis and treatment of rare type of hepatic benign space occupying lesions. \u0000 \u0000 \u0000Methods \u0000The clinical data of 113 patients with rare type of hepatic benign space occupying lesions confirmed by surgery and pathology from Jan 2009 to Dec 2018 were retrospectively analyzed. \u0000 \u0000 \u0000Results \u0000There were 51 males and 62 females , age ranging from 12 to 83 years, with an average of 44.3 years. 91.2% of the 113 cases were single lesions and 8.8% were multiple lesions. Surgical methods included hepatectomy in 98 cases, ablation therapy in 12 cases and hepatectomy combined with ablation in 3 cases. There were 21 types of pathology in 113 patients. The top five types were focal nodular hyperplasia (30 cases), hepatocellular adenoma (16 cases), dysplasia nodules (14 cases), perivascular epithelioid cell tumors (12 cases), and mucinous cystic neoplasms (11 cases), accounting for 73.5% cases. All the patients were alive in the follow-up period ranging from 6 to 120 months. \u0000 \u0000 \u0000Conclusion \u0000Preoperative diagnosis of rare benign space-occupying lesions of the liver is very difficult. Preoperative MRI is helpful for diagnosis. Conservative treatment or follow-up observation can be considered for the type malignancy have never been reported. For the borderline types or those with difficulty in definite diagnosis, surgical removal is recommended. \u0000 \u0000 \u0000Key words: \u0000Liver neoplasms; Surgical procedures, operatives","PeriodicalId":66425,"journal":{"name":"中华普通外科杂志","volume":"35 1","pages":"96-99"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42962474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comprehensive treatment for acute iliac femoral vein thrombosis complicating left iliac vein compression 急性髂股静脉血栓形成合并左髂静脉压迫的综合治疗

中华普通外科杂志 Pub Date : 2020-02-25 DOI: 10.3760/CMA.J.ISSN.1007-631X.2020.02.009

Jie Zhang, Dafang Liu, Hui-rong Zhao, Changbao Yan, Peiqiang Geng, Yanyang Wang, Liang Zhao

{"title":"Comprehensive treatment for acute iliac femoral vein thrombosis complicating left iliac vein compression","authors":"Jie Zhang, Dafang Liu, Hui-rong Zhao, Changbao Yan, Peiqiang Geng, Yanyang Wang, Liang Zhao","doi":"10.3760/CMA.J.ISSN.1007-631X.2020.02.009","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-631X.2020.02.009","url":null,"abstract":"Objective \u0000To explore the significance of comprehensive treatment including anticoagulation, inferior vena cava filter implantation, mechanical thrombectomy, iliac vein angioplasty and stent placement and catheter-directed thrombolysis(CDT) in the treatment of acute iliac femoral vein thrombosis on the basis of left iliac vein compression. \u0000 \u0000 \u0000Methods \u0000In this study 61 patients were enrolled at Beijing Luhe Hospital, Capital Medical University between Mar 2013 and Mar 2019 in anticoagulation combined with CDT group and comprehensive treatment group. Short-term venous recanalization rate scores and long-term proximal valvular function of left femoral vein were compared. The survival curve was drawn using kaplan-meier method, and incidence of PTS was compared with the Log rank test. \u0000 \u0000 \u0000Result \u0000The short-term venous recanalization rate scores of the patients in the comprehensive treatment group were higher than scores of the patients in the traditional treatment group(t=9.872, P<0.001). 16 patients developed PTS. The incidence of PTS in the comprehensive treatment group was lower than that in the traditional treatment group(χ2=7.146, P=0.008). Patients in comprehensive treatment group kept a better function of the proximal valvular of left femoral vein than patients in the traditional treatment group(χ2=23.834, P<0.001). \u0000 \u0000 \u0000Conclusion \u0000The comprehensive treatment can effectively reduce the occurrence of long-term PTS in patients with acute iliac femoral vein thrombosis complicated with left iliac vein compression, and Improves the quality of patients′ life. \u0000 \u0000 \u0000Key words: \u0000Venous thrombosis; Angioplasty; Mechanical thrombolysis","PeriodicalId":66425,"journal":{"name":"中华普通外科杂志","volume":"35 1","pages":"120-123"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44191508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of PCOA+ NOSES with 3D high-resolution laparoscopic radical operation for left sided colon cancer PCOA+NOSES联合三维高分辨率腹腔镜左半结肠癌根治术的应用

中华普通外科杂志 Pub Date : 2020-02-25 DOI: 10.3760/CMA.J.ISSN.1007-631X.2020.02.006

Junwei Bai, Chao Zhang, Zhi-kai Wang, Hui Zhang, Yi Xie, Junmeng Li, Chunbo Zhang

{"title":"Application of PCOA+ NOSES with 3D high-resolution laparoscopic radical operation for left sided colon cancer","authors":"Junwei Bai, Chao Zhang, Zhi-kai Wang, Hui Zhang, Yi Xie, Junmeng Li, Chunbo Zhang","doi":"10.3760/CMA.J.ISSN.1007-631X.2020.02.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-631X.2020.02.006","url":null,"abstract":"Objective \u0000To evaluate the PCOA+ NOSES with 3D laparoscopy in the left colon cancer radical resection. \u0000 \u0000 \u0000Methods \u0000In this study 64 patients underwent PCOA+ NOSES with 3D laparoscopic radical operation of the left colon cancer in He′nan Provincial People′s Hospital from June 2016 to June 2019. \u0000 \u0000 \u0000Result \u0000The operation time was(146±53)min, time for anastomosis of PCOA was(30.3±2.5)min, intraoperative blood loss was (51±26)ml, the bowel function recovered in (2.1±1.3)d, the time to semi-liquid diet was (4.1±1.4)d, time to being up and about was (1.3±0.6) d, the mean postoperative hospital stay was (5.4±1.4)d, the number of lymph nodes dissection was (22±9.5), the inhospital cost was (4.1±1.2) ten thousand yuan. Complications developed in 4 patients(6%), one of intestinal obstruction, one of anastomotic leakage, one patient had ascites and infection, one suffred pulmonary infection. \u0000 \u0000 \u0000Conclusion \u0000The PCOA+ NOSES with 3D laparoscope in the left colon cancer radical resection was safe and feasible. \u0000 \u0000 \u0000Key words: \u0000Colonic neoplasms; Anastomosis, surgical; Colectomy; Laparoscopy","PeriodicalId":66425,"journal":{"name":"中华普通外科杂志","volume":"35 1","pages":"108-111"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44472299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation between preoperative serum alanine transaminase and the prognosis of postoperative gastric cancer patients 癌症患者术前血清丙氨酸转氨酶与预后的相关性

中华普通外科杂志 Pub Date : 2020-01-25 DOI: 10.3760/CMA.J.ISSN.1007-631X.2020.01.005

B. Han, Yimin Wang, Yingwei Xue

{"title":"Correlation between preoperative serum alanine transaminase and the prognosis of postoperative gastric cancer patients","authors":"B. Han, Yimin Wang, Yingwei Xue","doi":"10.3760/CMA.J.ISSN.1007-631X.2020.01.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-631X.2020.01.005","url":null,"abstract":"Objective \u0000To study the relationship between preoperative serum ALT and clinicopathological factors in patients with gastric cancer after radical gastrectomy. \u0000 \u0000 \u0000Methods \u0000At the Department of Gastrointestinal Surgery, Tumor Hospital of Harbin Medical University from Jan 2008 to Dec 2010, 491 patients were grouped according to ROC curve cut-off point of serum ALT. The relationship between ALT and clinical factors was analyzed, and single-factor and multi-factor survival analysis was performed. \u0000 \u0000 \u0000Results \u0000There were 201 patients with ALT ≤ 20.05 U/L, and 290 patients with ALT >20.05 U/L. Serum ALT was associated with age(χ2=11.231, P 20.05U/L were 83.5%, 51.4%, 42.1% and 66.2%, 27.4%, 15.7%. There was significant difference between the two groups (χ2=41.711, P<0.001). Multivariate analysis showed that tumor TNM stage(HR=1.882, 95% CI: 1.468-2.413, P<0.001), tumor infiltration depth(HR=1.161, 95% CI: 1.020-1.322, P=0.024), lymph node metastasis(HR=1.177, 95% CI: 1.042-1.329, P=0.009), Hb(HR=0.726, 95% CI: 0.579-0.909, P=0.005), neutrophil to lymphocyte rate(HR=1.275, 95% CI: 1.002-1.623, P=0.048)and ALT(HR=2.191, 95% CI: 1.754-2.738, P<0.001)were independent risk factors for the prognosis. \u0000 \u0000 \u0000Conclusions \u0000Serum ALT is an independent risk factor for the prognosis of gastric cancer patients after radical gastrectomy. \u0000 \u0000 \u0000Key words: \u0000Stomach neoplasms; Alanine transaminase; Prognosis","PeriodicalId":66425,"journal":{"name":"中华普通外科杂志","volume":"35 1","pages":"13-16"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46549601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combined detection of MLNR and serum CEA in predicting preoperative distant metastasis of stage II-III colon cancer 联合检测MLNR和血清CEA对II-III期结肠癌术前远处转移的预测价值

中华普通外科杂志 Pub Date : 2020-01-25 DOI: 10.3760/CMA.J.ISSN.1007-631X.2020.01.006

W. Han, Shenyi Wan, F. Deng, Mancai Wang, Xiaodong Xu, Youcheng Zhang

{"title":"Combined detection of MLNR and serum CEA in predicting preoperative distant metastasis of stage II-III colon cancer","authors":"W. Han, Shenyi Wan, F. Deng, Mancai Wang, Xiaodong Xu, Youcheng Zhang","doi":"10.3760/CMA.J.ISSN.1007-631X.2020.01.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-631X.2020.01.006","url":null,"abstract":"Objective \u0000To investigate the predictive value of metastatic lymph node ratio (MLNR) combined with preoperative serum carcinoembryonic antigen (CEA) in the detection of distant metastasis of stage Ⅱ-Ⅲ colon cancer after radical resection. \u0000 \u0000 \u0000Methods \u0000A retrospective study was performed on the clinical data of 325 patients with stage Ⅱ-Ⅲ colon cancer undergoing radical resection in the Second Hospital of Lanzhou University from Jan 2010 to Jan 2015. \u0000 \u0000 \u0000Results \u0000MLNR was correlated with the maximum diameter of tumors, the degree of differentiation of tumors, clinical TNM stage and distant metastasis (P<0.05), serum CEA was correlated with the maximum diameter of tumors, clinical TNM stage, nerve or vascular invasion and distant metastasis (P<0.05). Logistic regression analysis showed that low differentiation of tumor tissue, TNM Ⅲ stage, high MLNR and high serum CEA were independent risk factors for distant metastasis of colon cancer after radical operation. \u0000 \u0000 \u0000Conclusions \u0000The combined detection of MLNR and serum CEA has a good predictive value for distant metastasis with stage Ⅱ-Ⅲ colon cancer. \u0000 \u0000 \u0000Key words: \u0000Colon neoplasms; Lymphatic metastasis; Carcinoembryonic antigen; Prognosis","PeriodicalId":66425,"journal":{"name":"中华普通外科杂志","volume":"35 1","pages":"17-20"},"PeriodicalIF":0.0,"publicationDate":"2020-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44637456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0