Clinical analysis on 13 cases of hepatic lymphoepithelioma-like carcinoma

中华普通外科杂志 Pub Date : 2020-02-25 DOI:10.3760/CMA.J.ISSN.1007-631X.2020.02.012

Jianjun Xu, Xiang Cheng, Xingdi Zhou, Yang Gao, Weimin Wang, Q. Zheng, Shao-bo Hu

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Abstract

Objective To summarize the clinical characteristics of hepatic lymphoepithelioma-like carcinoma, and to explore the diagnosis and treatment strategies of hepatic lymphoepithelioma-like carcinoma. Methods A retrospectively analysis on 13 patients with liver lymphoepithelioma-like carcinoma in Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, between March 2005 and May 2019 were carried out. Results 8 cases were male , 5 were female, median age was 45 years (27 to 68 y). There were 8 cases of intrahepatic cholangiocytic lymphoepithelioma-like carcinoma, 4 cases of hepatocytic lymphoepithelioma-like carcinoma, and 1 case of mixed hepatocytic and cholangiocytic lymphoepithelioma-like carcinoma . All patients received partial hepatectomy and postoperative comprehensive treatment. The patients were followed from 6 months to 7 years. Only one patient died, and the other patients were all in a tumor-free state. Conclusion Primary hepatic lymphoepithelioma-like carcinoma is a rare liver cancer. It is confirmed mainly by pathological examination and immunohistochemistry. With surgery as the main treatment, prognosis is usually fair. Key words: Liver neoplasms; Hepatectomy

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肝淋巴上皮瘤样癌13例临床分析

目的总结肝淋巴上皮瘤样癌的临床特点，探讨肝淋巴上皮癌样癌的诊断和治疗策略。方法对华中科技大学同济医学院协和医院2005年3月至2019年5月收治的13例肝淋巴上皮瘤样癌患者进行回顾性分析。结果男性8例，女性5例，中位年龄45岁（27～68岁）。肝内胆管细胞淋巴上皮瘤样癌8例，肝细胞淋巴上皮癌样癌4例，肝、胆管细胞混合性淋巴上皮瘤状癌1例。所有患者均接受肝部分切除术及术后综合治疗。随访6个月至7年。只有一名患者死亡，其他患者均处于无肿瘤状态。结论原发性肝淋巴上皮瘤样癌是一种罕见的癌症。主要通过病理检查和免疫组化证实。以手术为主要治疗手段，预后通常尚可。关键词：肝肿瘤；肝切除术

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中华普通外科杂志

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