Clinical analysis on 13 cases of hepatic lymphoepithelioma-like carcinoma

Objective To summarize the clinical characteristics of hepatic lymphoepithelioma-like carcinoma, and to explore the diagnosis and treatment strategies of hepatic lymphoepithelioma-like carcinoma. Methods A retrospectively analysis on 13 patients with liver lymphoepithelioma-like carcinoma in Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, between March 2005 and May 2019 were carried out. Results 8 cases were male , 5 were female, median age was 45 years (27 to 68 y). There were 8 cases of intrahepatic cholangiocytic lymphoepithelioma-like carcinoma, 4 cases of hepatocytic lymphoepithelioma-like carcinoma, and 1 case of mixed hepatocytic and cholangiocytic lymphoepithelioma-like carcinoma . All patients received partial hepatectomy and postoperative comprehensive treatment. The patients were followed from 6 months to 7 years. Only one patient died, and the other patients were all in a tumor-free state. Conclusion Primary hepatic lymphoepithelioma-like carcinoma is a rare liver cancer. It is confirmed mainly by pathological examination and immunohistochemistry. With surgery as the main treatment, prognosis is usually fair. Key words: Liver neoplasms; Hepatectomy