Diagnosis and treatment of rare types of hepatic benign space occupying lesions

Abstract

Objective To summarize the experience of diagnosis and treatment of rare type of hepatic benign space occupying lesions. Methods The clinical data of 113 patients with rare type of hepatic benign space occupying lesions confirmed by surgery and pathology from Jan 2009 to Dec 2018 were retrospectively analyzed. Results There were 51 males and 62 females , age ranging from 12 to 83 years, with an average of 44.3 years. 91.2% of the 113 cases were single lesions and 8.8% were multiple lesions. Surgical methods included hepatectomy in 98 cases, ablation therapy in 12 cases and hepatectomy combined with ablation in 3 cases. There were 21 types of pathology in 113 patients. The top five types were focal nodular hyperplasia (30 cases), hepatocellular adenoma (16 cases), dysplasia nodules (14 cases), perivascular epithelioid cell tumors (12 cases), and mucinous cystic neoplasms (11 cases), accounting for 73.5% cases. All the patients were alive in the follow-up period ranging from 6 to 120 months. Conclusion Preoperative diagnosis of rare benign space-occupying lesions of the liver is very difficult. Preoperative MRI is helpful for diagnosis. Conservative treatment or follow-up observation can be considered for the type malignancy have never been reported. For the borderline types or those with difficulty in definite diagnosis, surgical removal is recommended. Key words: Liver neoplasms; Surgical procedures, operatives