Thi Yen Hong Huynh, Huu Ngan Thy Truong, Thanh Thao Tran, Ngoc Ba Vu
{"title":"In situ gamma ray spectrometry for environmental monitoring: Full Spectrum Analysis and dose assessment","authors":"Thi Yen Hong Huynh, Huu Ngan Thy Truong, Thanh Thao Tran, Ngoc Ba Vu","doi":"10.1007/s10967-025-10359-w","DOIUrl":"10.1007/s10967-025-10359-w","url":null,"abstract":"<div><p>This study developed and validated an in situ Full Spectrum Analysis (FSA) method using a NaI(Tl) detector for environmental radiation monitoring in Ho Chi Minh City. Mean activity concentrations of <sup>238</sup>U (21.8 Bq kg⁻<sup>1</sup>) and <sup>232</sup>Th (33.8 Bq kg⁻<sup>1</sup>) were near or below global averages, while <sup>40</sup>K (57.8 Bq kg⁻<sup>1</sup>) was notably depleted. Anthropogenic <sup>137</sup>Cs was negligible. Derived radiological hazard indices, including an average outdoor annual effective dose of 0.04 mSv y⁻<sup>1</sup>, were well within international safety limits. The findings confirm the method’s utility and indicate a low terrestrial gamma radiation risk in the surveyed urban areas.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"334 9","pages":"6267 - 6280"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145210232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A reduced-volume manganese bath facility for low emission rate neutron source measurement at CIAE","authors":"Haixian Zhang, Yina Liu, Chunjuan Li, Mingzhe Song, Zhiqiang Wang, Xinyu Xu, Hailong Luo","doi":"10.1007/s10967-025-10339-0","DOIUrl":"10.1007/s10967-025-10339-0","url":null,"abstract":"<div><p>The CIAE manganese bath facility has been employed to measure the emission rate of a radionuclide neutron source in 5 × 10<sup>5</sup>s<sup>−1</sup> ~ 1 × 10<sup>9</sup>s<sup>−1</sup> for nearly forty years. In order to measure neutron sources with lower emission rate, a reduced-volume manganese bath facility was developed. By reducing the bath radius to increasing the specific activity of the solution, the emission rate of neutron sources which is nearly an order of magnitude lower than the previous manganese bath can be measured by the reduced-volume manganese bath system. Two neutron sources with lower emission rates which were 4.09 × 10<sup>4</sup> s<sup>−1</sup> and 1.75 × 10<sup>5</sup> s<sup>−1</sup> with an uncertainties of < 1.5% (<i>k</i> = 1) have been measured with the new bath.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"334 9","pages":"5971 - 5977"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145210309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ceren Sezgin, Emre Uygur, Yasemin Parlak, Busra Karatay, Sabri Barutca, Ahmet Dirican, Tevfik Sinan Sozen, Guven Arslan, Coskun Harmansah, Turkay Toklu, Ugur Avcibasi, Zumrut Biber Muftuler, Omer Aras, Gul Gumuser
{"title":"Terbium-161 PSMA therapy in mCRPC patient based on an optimized radiolabeling protocol","authors":"Ceren Sezgin, Emre Uygur, Yasemin Parlak, Busra Karatay, Sabri Barutca, Ahmet Dirican, Tevfik Sinan Sozen, Guven Arslan, Coskun Harmansah, Turkay Toklu, Ugur Avcibasi, Zumrut Biber Muftuler, Omer Aras, Gul Gumuser","doi":"10.1007/s10967-025-10352-3","DOIUrl":"10.1007/s10967-025-10352-3","url":null,"abstract":"<div><p>This study presents a novel radiolabeling technique for [<sup>161</sup>Tb]-PSMA-617 in metastatic castration-resistant prostate cancer (mCRPC). The research focused on assessing the radiochemical yield, in vivo stability, and pharmacokinetics of [<sup>116</sup> Tb]-PSMA-617 in a clinical setting. Using a sodium acetate buffer and ascorbic acid, a high radiochemical yield (97.98% ± 2.01) was achieved, ensuring stability and purity. The therapy was evaluated to a 77-year-old mCRPC patient resistant to [177Lu]-PSMA-617, showing favorable biodistribution and urinary excretion. Despite initial stability, disease progression occurred, with a TP53 mutation identified via liquid biopsy. While the method holds promise for targeted radionuclide therapy, resistance mechanisms remain a challenge, necessitating further research for optimized patient selection and treatment strategies.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"334 9","pages":"5979 - 5988"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145210308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anionically modified chitosan-coated magnetic silica particles with enhanced adsorption for uranium removal","authors":"Weiran Wang, Hui He, Zhifen Wang","doi":"10.1007/s10967-025-10366-x","DOIUrl":"10.1007/s10967-025-10366-x","url":null,"abstract":"<div><p>In this study, two new, highly selective, acid-resistant and reusable functionalized magnetic chitosan-based composites (FOS@C-DTPA and FOS@C-PBTCA) were successfully prepared. The adsorption performance of the composites was systematically evaluated through controlled variations in solution pH, exposure time, and starting uranium content, while the underlying mechanisms for uranium uptake were analyzed using kinetic models and thermodynamic equilibrium studies. In the multi-ion competition experiments, a high degree of selectivity for U(VI) was demonstrated; good cyclic regeneration performance was shown in both cycling experiments. XPS analysis combined with complementary characterization techniques demonstrated that uranium adsorption was predominantly caused by surfaces complexation between U(VI) ions and the composite material’s abundant functional groups rich in carbon, nitrogen, and oxygen on the composite material. At pH 5, FOS@C-PBTCA demonstrated an adsorption capacity of 303.53 mg·g<sup>−1</sup>, while FOS@C-DTPA achieved 487.39 mg·g<sup>−1</sup> at pH 6. The proposed approach aims to achieve efficient and selective uranium extraction by leveraging an anion-assisted synergistic mechanism, enabled through the rational design of acid-resistant and recyclable magnetic composite adsorbents.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"334 9","pages":"6295 - 6303"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145210229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tita Puspitasari, Adam Febriyanto Nugraha, Farah Nurlidar, Ade Lestari Yunus, Muhammad Caessar, Maurice Efroza, Mochamad Chalid, Uwe Gohs
{"title":"Utilizing gamma irradiation-induced oxidation on recycled high-density polyethylene to produce a compatibilizer for fabrication of waste-derived wood-polymer composite","authors":"Tita Puspitasari, Adam Febriyanto Nugraha, Farah Nurlidar, Ade Lestari Yunus, Muhammad Caessar, Maurice Efroza, Mochamad Chalid, Uwe Gohs","doi":"10.1007/s10967-025-10358-x","DOIUrl":"10.1007/s10967-025-10358-x","url":null,"abstract":"<div><p>In fabrication of wood polymer composites (WPC), a compatibilizer plays an important role in enhancing interfacial adhesion between polymeric matrix and wood filler. This study investigated the effects of gamma irradiation-induced oxidation on recycled high-density polyethylene (rHDPE) to be used as a compatibilizer for WPC production. FTIR analysis showed that gamma irradiation induces significant functional group modifications, as demonstrated by the rising of carbonyl index as the irradiation doses increase up to 200 kGy. Differential scanning calorimetry analysis reveals that irradiation lowers melting temperature, indicating a chain scission in the rHDPE. Additional assessments of wetting angle, work of adhesion, spreading coefficient, and surface energy confirmed the aforementioned findings. Mechanical testing of the WPC made from rHDPE reinforced with oil palm empty fruit bunch (OPEFB) showed that an optimal formulation of 78 wt% rHDPE, 2 wt% irradiated rHDPE (i-rHDPE) 200 kGy as a compatibilizer, and 20 wt% OPEFB yields the most optimum mechanical strength. This indicates a strong interfacial adhesion between the rHDPE and OPEFB in the presence of i-rHDPE as the compatibilizer. These findings suggest that gamma irradiation has strong potential to induce surface modification through radiation induced-oxidation on the rHDPE and enhance its hydrophilicity properties. Thus, it can be utilized as a compatibilizer for the WPC production.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"334 9","pages":"6187 - 6198"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145210230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Construction of various nanostructured cerium oxide for highly efficient adsorption of uranium","authors":"Guofeng Wang, Yishuo Zhang, Xiaoyan Li, Yibao Liu","doi":"10.1007/s10967-025-10341-6","DOIUrl":"10.1007/s10967-025-10341-6","url":null,"abstract":"<div><p>Nanostructured cerium oxide (CeO<sub>2</sub>) with various morphologies, including nanoparticles, nanorods, and mixture thereof, was synthesized for the purpose of removing uranium (U(VI)) from aqueous solutions. The influence of the morphology of nanostructured CeO<sub>2</sub> on its adsorption performance for uranium was investigated. Additionally, several factors affecting the adsorption experiments—such as pH, initial U(VI) concentration, and contact time—were thoroughly examined. The results demonstrated that nanostructured CeO<sub>2</sub> exhibit rapid (30 min to reach equilibrium) and high adsorption capacities (up to 561.22 mg⋅g<sup>−1</sup> for nanoparticles, 408.48 mg⋅g<sup>−1</sup> for nanorods, and 507.62 mg⋅g<sup>−1</sup> for mixture).</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"334 9","pages":"6129 - 6140"},"PeriodicalIF":1.6,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145210821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correlation between soil parameters, soil gas radon and its exhalation rate into ambient air in Kuwait","authors":"Reem Aljber, Fouad Shaaban, Darwish Al-Azmi","doi":"10.1007/s10967-025-10331-8","DOIUrl":"10.1007/s10967-025-10331-8","url":null,"abstract":"<div><p>Correlation between soil characteristics and field radon measurements was studied at 20 sites in Kuwait. Soil samples were collected from the same sites and analyzed for grain size. Results show that the outdoor radon concentrations had a mean value of 8.9 Bq m<sup>−3</sup>. The radon exhalation rates ranged from 2.8 to 18.2 mBq m<sup>−2</sup> s<sup>−1</sup> with a mean of 9.7 mBq m<sup>−2</sup> s<sup>−1</sup>. Radon exhalation rates were higher for dry, friable, gravelly sand soil when compared to those recorded in the wet and compacted muddy sand soil. A poor correlation was observed between the radon exhalation rates and soil gas radon concentrations.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"334 9","pages":"5989 - 6000"},"PeriodicalIF":1.6,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145210823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Synthesis and quality control of [225Ac][Ac-DOTATATE]: feasibility of the targeted alpha therapy (TAT) in conventional clinical pharmacy equipped for Tc-99 m in Pakistan","authors":"Shakera Khatoon Rizvi, Amna Javed, Qaiser Khan","doi":"10.1007/s10967-025-10346-1","DOIUrl":"10.1007/s10967-025-10346-1","url":null,"abstract":"<div><p>Actinium-225-labeled DOTATATE is a promising candidate for targeted alpha therapy (TAT) of neuroendocrine tumors due to its favorable radionuclide properties and ease of synthesis. This study evaluates the feasibility of using standard QC methods, typically used for Tc-99 m, for TAT with Ac-225. [225Ac][Ac-DOTATATE] was synthesized with > 92 ± 2% radiochemical purity and the product remained stable for 24 h. Gamma spectrometry showed > 99.9% radionuclide purity. ITLC-SG paper in aqueous acetonitrile resolved radiochemical species effectively, with Rf values of 0.2 for free radiometal and 0.8–0.9 for the labeled peptide while opposite behavior was observed with sodium citrate as mobile phase. These results demonstrate that standard QC infrastructure in Pakistan is adequate for alpha therapy, facilitating routine clinical application.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"334 9","pages":"6349 - 6358"},"PeriodicalIF":1.6,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145210820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saba Shirin, Syed Qaiser Shah, Ralph Santos-Oliveira, Derya Ilem-Ozdemir, Muhammad Imran, Nadeem Ahmed Lodhi
{"title":"Synthesis and evaluation of [99mTc]Tc–octapa–necitumumab for targeted imaging of squamous non-small cell lung cancer","authors":"Saba Shirin, Syed Qaiser Shah, Ralph Santos-Oliveira, Derya Ilem-Ozdemir, Muhammad Imran, Nadeem Ahmed Lodhi","doi":"10.1007/s10967-025-10365-y","DOIUrl":"10.1007/s10967-025-10365-y","url":null,"abstract":"<div><p>This study reports the synthesis and in vitro as well as in vivo evaluation of [<sup>99m</sup>Tc]Tc–octapa–necitumumab for targeted imaging of squamous non-small cell lung cancer (NSCLC). Necitumumab was conjugated with p-SCN-Bn–H<sub>4</sub>Octapa and efficiently labeled with technetium-99m under mild conditions, yielding excellent radiochemical purity and favorable in vitro stability. The [<sup>99m</sup>Tc]Tc–octapa–necitumumab presented strong EGFR-specific in vitro binding and internalization in HCC827 cells. Biodistribution studies in tumor-bearing mice showed a tumor uptake of 5.85 ± 0.1% ID/g at 4 h post-injection, with promising tumor-to-organ ratios, including 2.07 ± 0.18 for tumor-to-blood, 2.49 ± 0.20 for tumor-to-blocked tumor, 2.21 ± 0.18 for tumor-to-liver, 2.02 ± 0.15 for tumor-to-lung, 1.14 ± 0.06 for tumor-to-kidney, and 3.44 ± 0.57 for tumor-to-muscle. Rabbit SPECT studies validated selective tumor localization with insignificant off-target accumulation. These findings categorize [<sup>99m</sup>Tc]Tc–octapa–necitumumab as a novel radiotracer with potential for EGFR-targeted imaging in squamous NSCLC.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"334 9","pages":"6281 - 6294"},"PeriodicalIF":1.6,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145210819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nguyen An Trung, Nguyen Hao Quang, Nguyen Thi Thu Ha, Duong Duc Thang, Nguyen Chi Thanh, Phung Nhu Hai
{"title":"Quantification of Ra-226 and U-235 in soil using HPGe gamma spectra and linear regression","authors":"Nguyen An Trung, Nguyen Hao Quang, Nguyen Thi Thu Ha, Duong Duc Thang, Nguyen Chi Thanh, Phung Nhu Hai","doi":"10.1007/s10967-025-10348-z","DOIUrl":"10.1007/s10967-025-10348-z","url":null,"abstract":"<div><p>This study aims to develop a linear regression model using the Scikit-Learn libraries for direct quantification of Ra-226 and U-235 in soil using HPGe gamma spectrometers. The proposed approach eliminates the need for radioactive equilibrium with Rn-222 and its decay products, as well as bypasses conventional spectral correction procedures. The model was trained on a dataset comprising 20,000 synthetic 8192-channel gamma spectra and achieved quantification accuracies within 15% for both radionuclides. The findings highlight the model’s simplicity and reliability, underscoring its potential as a rapid and practical tool for routine environmental radioactivity assessment, particularly for overcoming challenges posed by spectral overlap and equilibrium constraints.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"334 9","pages":"6055 - 6061"},"PeriodicalIF":1.6,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145210822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}