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Assessment of human organs absorbed dose of 113mIn-BBN: extrapolation from mice biodistribution data using different phantom models 人体器官113mIn-BBN吸收剂量的评估：基于不同模型小鼠生物分布数据的推断
IF 1.6 3区 化学
Journal of Radioanalytical and Nuclear Chemistry Pub Date : 2026-02-05 DOI: 10.1007/s10967-026-10753-y
Zahra Saberi, Elham Saeedzadeh, Hassan Yousefnia, Samaneh Zolghadri, Saeed Rajabifar
{"title":"Assessment of human organs absorbed dose of 113mIn-BBN: extrapolation from mice biodistribution data using different phantom models","authors":"Zahra Saberi,&nbsp;Elham Saeedzadeh,&nbsp;Hassan Yousefnia,&nbsp;Samaneh Zolghadri,&nbsp;Saeed Rajabifar","doi":"10.1007/s10967-026-10753-y","DOIUrl":"10.1007/s10967-026-10753-y","url":null,"abstract":"<div><p>This study investigated the absorbed radiation dose of <sup>113m</sup>In-BBN, targeting gastrin-releasing peptide receptors which are overexpressed in various human cancers. The compound was prepared under optimized conditions, with its radiochemical purity confirmed by RTLC and HPLC. Biodistribution was studied in tumor-bearing mice, and human organ absorbed doses were estimated using mouse data and MIRD method. Results showed the highest absorbed doses in the pancreas and kidneys with the average value of 0.0080 and 0.0034 mGy/MBq, respectively. Based on dosimetric estimates derived from tumor-bearing mice biodistribution data, <sup>113m</sup>In-BBN demonstrated comparatively lower absorbed dose than selected <sup>67</sup>Ga- and <sup>99m</sup>Tc-labeled radiopharmaceuticals.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"335 3","pages":"1983 - 1993"},"PeriodicalIF":1.6,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147631822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Balsa wood/ZIF-8 composite material for efficient uranium adsorption from aqueous solutions 巴尔沙木/ZIF-8复合材料对水溶液中铀的高效吸附
IF 1.6 3区 化学
Journal of Radioanalytical and Nuclear Chemistry Pub Date : 2026-02-05 DOI: 10.1007/s10967-026-10754-x
Shan Gao, Li-peng Wang, Dongxu Gu
{"title":"Balsa wood/ZIF-8 composite material for efficient uranium adsorption from aqueous solutions","authors":"Shan Gao,&nbsp;Li-peng Wang,&nbsp;Dongxu Gu","doi":"10.1007/s10967-026-10754-x","DOIUrl":"10.1007/s10967-026-10754-x","url":null,"abstract":"<div><p>With the rapid growth of nuclear power generation and fuel processing, the treatment of nuclear industry wastewater has become a major problem, and if not handled properly, it will pose a potential threat to the ecological environment and human health. A novel ZIF-8@Balsa wood composite aerogel was synthesized for efficient uranium adsorption from water. The material exhibited a maximum capacity of 399 mg·g⁻<sup>1</sup> at pH 4, following the Langmuir model and pseudo-second-order kinetics. It demonstrated excellent selectivity, reusability over four cycles, and effective performance in complex water matrices. The composite presents a sustainable adsorbent for uranium recovery in environmental remediation.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"335 3","pages":"2003 - 2013"},"PeriodicalIF":1.6,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147631792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preclinical evaluation of a 64Cu-labeled αvβ6-targeting peptide PET probe for pancreatic cancer: from radiometal production to molecular probe validation 64cu标记αvβ6靶向肽PET胰腺癌探针的临床前评价：从放射性金属生产到分子探针验证
IF 1.6 3区 化学
Journal of Radioanalytical and Nuclear Chemistry Pub Date : 2026-02-05 DOI: 10.1007/s10967-026-10747-w
Xiao Pang, Liujing Zhao, Yanqin Yu, Yousheng Zhan, Yuchuan Zhou, Daiyuan Ma, Suping Li
{"title":"Preclinical evaluation of a 64Cu-labeled αvβ6-targeting peptide PET probe for pancreatic cancer: from radiometal production to molecular probe validation","authors":"Xiao Pang,&nbsp;Liujing Zhao,&nbsp;Yanqin Yu,&nbsp;Yousheng Zhan,&nbsp;Yuchuan Zhou,&nbsp;Daiyuan Ma,&nbsp;Suping Li","doi":"10.1007/s10967-026-10747-w","DOIUrl":"10.1007/s10967-026-10747-w","url":null,"abstract":"<div><p>Pancreatic cancer exhibits a high mortality rate globally, making precise diagnosis particularly critical. Integrin αvβ6 is a promising target for pancreatic cancer imaging, however, high gastrointestinal uptake has been a significant challenge in the clinical translation of previously developed αvβ6-targeted PET probes. In this study, we produced and purified high-quality <sup>64</sup>Cu using a medical cyclotron, and developed a <sup>64</sup>Cu-labeled αvβ6-targeted molecular imaging probe. Target specificity and binding affinity were evaluated through cell uptake, blocking, and competitive binding assays. Leveraging the relatively long half-life of <sup>64</sup>Cu, multi-time-point Micro-PET/CT imaging was performed to explore the feasibility of obtaining high tumor-to-background ratios with low gastrointestinal uptake at extended time points. <sup>64</sup>Cu-αvβ6 exhibits high affinity for integrin αvβ6 both in vitro and in vivo. Micro-PET/CT imaging in BxPC-3 (αvβ6 +) tumor-bearing nude mice showed good tumor visualization at all time points, with radioactivity uptake still observed at 24 h. Gastrointestinal uptake was significantly reduced after 8 h, yielding high-quality images with favorable tumor-to-background ratios.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"335 3","pages":"1807 - 1816"},"PeriodicalIF":1.6,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147631795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Soil-to-plant 137Cs transfer factors in Western Amazon, Brazil 巴西亚马逊西部土壤-植物137Cs转移因子
IF 1.6 3区 化学
Journal of Radioanalytical and Nuclear Chemistry Pub Date : 2026-02-05 DOI: 10.1007/s10967-026-10751-0
A. N. S. Geber Filho, A. Costa-Gonçalves, M. V. Licínio
{"title":"Soil-to-plant 137Cs transfer factors in Western Amazon, Brazil","authors":"A. N. S. Geber Filho,&nbsp;A. Costa-Gonçalves,&nbsp;M. V. Licínio","doi":"10.1007/s10967-026-10751-0","DOIUrl":"10.1007/s10967-026-10751-0","url":null,"abstract":"<div><p>This study presents a assessment of <sup>137</sup>Cs activity concentrations in surface soils and food from the state of Acre, Western Amazon, Brazil, and soil-to-plant transfer factors (T<sub>F</sub>). Soil and food samples (common beans, bananas, cassava, and cassava flour) from six regions were analyzed by HPGe gamma spectrometry. T<sub>f</sub>values ranged from 0.02 (banana—Cruzeiro do Sul) to 1.88 (banana -Epitaciolandia). Significant relationships were observed between T<sub>F</sub> and soil parameters (pH, Al, Ca, K), reflecting the influence of soil parameters on radionuclide bioavailability. These findings contribute to the understanding of <sup>137</sup>Cs behavior in tropical agroecosystems and provide a regional baseline.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"335 3","pages":"1961 - 1968"},"PeriodicalIF":1.6,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147631821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of gamma irradiation for the decontamination of historical glass plate photographic negatives 伽玛辐照在历史玻璃底片去污中的应用
IF 1.6 3区 化学
Journal of Radioanalytical and Nuclear Chemistry Pub Date : 2026-02-03 DOI: 10.1007/s10967-026-10734-1
Maria Luiza E. Nagai, Elizabeth S. R. Somessari, Tatiana A. Reis, Pablo A. S. Vasquez
{"title":"Application of gamma irradiation for the decontamination of historical glass plate photographic negatives","authors":"Maria Luiza E. Nagai,&nbsp;Elizabeth S. R. Somessari,&nbsp;Tatiana A. Reis,&nbsp;Pablo A. S. Vasquez","doi":"10.1007/s10967-026-10734-1","DOIUrl":"10.1007/s10967-026-10734-1","url":null,"abstract":"<div><p>Ionizing radiation is an effective method for fungal decontamination of photographic heritage materials; however, its application to glass plate negatives may induce optical darkening due to radiation-induced defects in the glass matrix. This study investigates the influence of temperature during gamma irradiation and the potential of UVB light exposure as a non-thermal bleaching strategy. Historical glass plate negatives were irradiated at 6 kGy under room temperature and dry-ice cooling, while common soda–lime–silica glass samples were used as analogues to quantify optical changes. Low-temperature processing mitigated color alterations without affecting decontamination efficacy, whereas UVB exposure promoted partial recovery of transparency in a dose-dependent manner. The combined approach offers a viable strategy for balancing biocidal effectiveness and optical preservation in glass-based photographic heritage.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"335 2","pages":"1215 - 1227"},"PeriodicalIF":1.6,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s10967-026-10734-1.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147558860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing cesium ion removal efficiency through Ti-based MOF/reduced graphene oxide composites: a central composite design approach 通过钛基MOF/还原氧化石墨烯复合材料提高铯离子去除效率：一种核心复合设计方法
IF 1.6 3区 化学
Journal of Radioanalytical and Nuclear Chemistry Pub Date : 2026-02-03 DOI: 10.1007/s10967-026-10719-0
Sodeh Sadjadi, Sareh Ammari Allahyari, Ali Yadollahi, Reza Saberi
{"title":"Enhancing cesium ion removal efficiency through Ti-based MOF/reduced graphene oxide composites: a central composite design approach","authors":"Sodeh Sadjadi,&nbsp;Sareh Ammari Allahyari,&nbsp;Ali Yadollahi,&nbsp;Reza Saberi","doi":"10.1007/s10967-026-10719-0","DOIUrl":"10.1007/s10967-026-10719-0","url":null,"abstract":"<div><p>A Ti-based metal–organic framework/reduced graphene oxide composite was prepared and utilized as an adsorbent for the removal of cesium ions. The effects of the adsorbent dosage, pH, contact time, and initial cesium concentration were investigated using the response surface methodology. Due to the analysis of variance, pH was the most effective factor influencing cesium removal. According to the results, the optimum conditions were pH 5.5.5 ± 0.1, an initial cesium concentration of 300 mg L<sup>−1</sup>, an adsorbent dosage of 0.05 ± 0.001 g, and a sorption duration of 90 min. The adsorption of cesium on the adsorbent was better represented by the Sips model.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"335 3","pages":"1869 - 1884"},"PeriodicalIF":1.6,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147631727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research on PGNAA online multi-element quantitative method based on SE-Auto-MBR neural network 基于SE-Auto-MBR神经网络的PGNAA在线多元素定量方法研究
IF 1.6 3区 化学
Journal of Radioanalytical and Nuclear Chemistry Pub Date : 2026-01-29 DOI: 10.1007/s10967-026-10745-y
You-Jian Zhang, Yan Zhang, Hao-ran Zhang, Xuan-di Hu, Shi-Liang Liu, Fang-zheng Luo, Ren-Bo Wang
{"title":"Research on PGNAA online multi-element quantitative method based on SE-Auto-MBR neural network","authors":"You-Jian Zhang,&nbsp;Yan Zhang,&nbsp;Hao-ran Zhang,&nbsp;Xuan-di Hu,&nbsp;Shi-Liang Liu,&nbsp;Fang-zheng Luo,&nbsp;Ren-Bo Wang","doi":"10.1007/s10967-026-10745-y","DOIUrl":"10.1007/s10967-026-10745-y","url":null,"abstract":"<div><p>Prompt Gamma Neutron Activation Analysis (PGNAA) enables real-time multi-element analysis of bulk materials but suffers from severe peak overlap, high noise, and complex backgrounds. To address these challenges, we propose SE-Autoencoder-MBR Net, an end-to-end deep learning model integrating Squeeze-and-Excitation (SE) attention, a symmetric autoencoder, and multi-branch heteroscedastic regression. The SE module recalibrates spectral features to enhance characteristic peaks of Ca, Si, Fe, and Al, while the autoencoder enforces spectral morphology preservation and implicit denoising. Crucially, the multi-branch regression outputs element concentrations alongside input-dependent uncertainty estimates, enabling adaptive task weighting via heteroscedastic negative log-likelihood. Experiments on a Monte Carlo–simulated cement dataset—verified for spectral fidelity against experimental measurements—demonstrate that the method outperforms CNN and PLS baselines, achieving an average R<sup>2</sup> &gt; 0.97 and RMSE &lt; 0.47. Ablation studies confirm the contribution of each module, highlighting the framework’s potential for accurate, robust, and uncertainty-aware industrial monitoring.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"335 3","pages":"1929 - 1943"},"PeriodicalIF":1.6,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147631626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hydrogeochemical and radium isotope characterization of the Capibaribe River’s water quality in Northeast Brazil 巴西东北部卡巴巴里伯河水质的水文地球化学和镭同位素特征
IF 1.6 3区 化学
Journal of Radioanalytical and Nuclear Chemistry Pub Date : 2026-01-29 DOI: 10.1007/s10967-025-10669-z
Taiwo Saheed Yinusa, José Araújo dos Santos Júnior, Zahily Herrero Fernández, Romilton dos Santos Amaral, Robert Fernandes de Melo, Josineide Marques do Nascimento Santos, Mariana Brayner Cavalcanti Freire Bezerra, Artur Paiva Coutinho, Marvic Ortueta Milan, Lino Angel Valcarcel Rojas, Jussiê Soares da Rocha, João Tadeu da Silva Santana, Yasmin Marques dos Santos, Rafaela Kelly Constantino Ferreira, João Marcos de Freitas Santos Silva, Guilherme Ramos de Mendonça
{"title":"Hydrogeochemical and radium isotope characterization of the Capibaribe River’s water quality in Northeast Brazil","authors":"Taiwo Saheed Yinusa,&nbsp;José Araújo dos Santos Júnior,&nbsp;Zahily Herrero Fernández,&nbsp;Romilton dos Santos Amaral,&nbsp;Robert Fernandes de Melo,&nbsp;Josineide Marques do Nascimento Santos,&nbsp;Mariana Brayner Cavalcanti Freire Bezerra,&nbsp;Artur Paiva Coutinho,&nbsp;Marvic Ortueta Milan,&nbsp;Lino Angel Valcarcel Rojas,&nbsp;Jussiê Soares da Rocha,&nbsp;João Tadeu da Silva Santana,&nbsp;Yasmin Marques dos Santos,&nbsp;Rafaela Kelly Constantino Ferreira,&nbsp;João Marcos de Freitas Santos Silva,&nbsp;Guilherme Ramos de Mendonça","doi":"10.1007/s10967-025-10669-z","DOIUrl":"10.1007/s10967-025-10669-z","url":null,"abstract":"<div><p>The Capibaribe River in Northeast Brazil is affected by water quality degradation driven by population growth and industrial activities. Seventeen water samples were analyzed for physicochemical parameters, major ions, radium isotopes, and the results were compared with Brazilian and WHO standards. Most samples showed elevated electrical conductivity, salinity, and chloride, indicating strong mineralization influenced by evaporation and human activities. Activity concentrations of <sup>226</sup>Ra and <sup>228</sup>Ra were mostly within permissible limits. Hydrochemical facies revealed Ca–HCO<sub>3</sub> and Cl–SO<sub>4</sub> water types. The study highlights the effect of natural processes and human activities on water quality, providing crucial insights for water management.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"335 3","pages":"1773 - 1786"},"PeriodicalIF":1.6,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147631670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of instrumental neutron activation analysis (INAA) with a californium neutron source for the determination of valuable metals in black shales of the Baltic Paleobasin 加利福尼亚中子源仪器中子活化分析（INAA）在测定波罗的海古盆地黑色页岩中有价金属中的应用
IF 1.6 3区 化学
Journal of Radioanalytical and Nuclear Chemistry Pub Date : 2026-01-29 DOI: 10.1007/s10967-026-10738-x
Sergei Ivannikov, Vladimir Ivanov, Nikita Markin, Larisa Zemskova, Igor Okunev
{"title":"Application of instrumental neutron activation analysis (INAA) with a californium neutron source for the determination of valuable metals in black shales of the Baltic Paleobasin","authors":"Sergei Ivannikov,&nbsp;Vladimir Ivanov,&nbsp;Nikita Markin,&nbsp;Larisa Zemskova,&nbsp;Igor Okunev","doi":"10.1007/s10967-026-10738-x","DOIUrl":"10.1007/s10967-026-10738-x","url":null,"abstract":"<div><p>Instrumental neutron activation analysis using a californium-252 neutron source (<sup>252</sup>Cf INAA) was applied for multi-element analysis of Dictyonema Shales from the Baltic Paleobasin. The method enabled rapid, precise determination of V, Mo, Sc, several rare earth elements (REEs: La, Sm, Eu, Dy), Au, and U in 54 samples without complex preparation. Their concentrations exceeded the respective Clarke values by factors of 3 to 35., with uranium enrichment driving high natural radioactivity (Raₑq up to 1734 Bq kg⁻<sup>1</sup>). A strong correlation (r = 0.95) between INAA-derived U and gamma-spectrometric <sup>226</sup>Ra confirmed analytical accuracy. Inter-element correlations (U–V–Mo–REEs) indicate co-enrichment and metallogenic potential.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"335 3","pages":"1905 - 1918"},"PeriodicalIF":1.6,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147631671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative analysis of biochemical marker responses and extracranial dose measurements in low and high dose 60Co gamma knife radiosurgery 低、高剂量60Co伽玛刀放射治疗中生化标志物反应及颅外剂量测定的比较分析
IF 1.6 3区 化学
Journal of Radioanalytical and Nuclear Chemistry Pub Date : 2026-01-29 DOI: 10.1007/s10967-026-10748-9
Bazhdar N. Mohammed, Asaad H. Ismail, Edrees M. Tahir, Hoshanc S. Rashid
{"title":"Comparative analysis of biochemical marker responses and extracranial dose measurements in low and high dose 60Co gamma knife radiosurgery","authors":"Bazhdar N. Mohammed,&nbsp;Asaad H. Ismail,&nbsp;Edrees M. Tahir,&nbsp;Hoshanc S. Rashid","doi":"10.1007/s10967-026-10748-9","DOIUrl":"10.1007/s10967-026-10748-9","url":null,"abstract":"<div><p>This study presents physiological responses and extracranial radiation exposure in patients undergoing Gamma Knife Radiosurgery using a practical, cost-effective, direct-reading novel dosimeter. Biochemical changes were assessed in two dose groups and radiation doses to body organs were quantified. High-dose treatment induced significant (<i>p</i> ≤ 0.05) hepatic stress and lipid metabolism alterations, with dose dependent changes across multiple organ systems. Extracranial organs received 0.001–0.017% of prescribed dose, with neck and chest regions most exposed. Larger collimators produced greater scattered radiation. This study uniquely combines scatter radiation dosimetry with comprehensive biochemical monitoring, revealing measurable systemic effects requiring enhanced protection protocols for patients undergoing Gamma Knife treatments to minimize secondary radiation risks.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"335 3","pages":"1857 - 1867"},"PeriodicalIF":1.6,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147631625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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