{"title":"Preparation and bioevaluation of a 99mTc-labeled small-molecular radiotracer for PD-L1 imaging","authors":"Xiang Xu, Yiyin Mao, Peng Zhou, Yujing Wu, Yaling Liu, Hongyong Wang, Chunxiong Lu, Pei Zou","doi":"10.1007/s10967-024-09901-z","DOIUrl":"10.1007/s10967-024-09901-z","url":null,"abstract":"<div><p>In this study, a <sup>99m</sup>Tc-labeled small molecule imaging probe [<sup>99m</sup>Tc]Tc-PG3C-CBM for PD-L1 imaging was designed. It showed a radiochemical yield of > 97% and good in vitro stability. Uptake in A375-hPD-L1 cells (17.07 ± 1.40%) was 4.5 times higher than in A375 cells (3.81 ± 0.19%). The probe demonstrated moderate PD-L1 affinity (K<sub>D</sub>: 11.6 ± 2.57 nM; IC<sub>50</sub>: 59.2 ± 2.40 nM). Additionally, SPECT/CT imaging and biodistribution results indicated that [<sup>99m</sup>Tc]Tc-PG3C-CBM was mainly metabolized by the liver and showed some accumulation at the tumor site. These results suggest that [<sup>99m</sup>Tc]Tc-PG3C-CBM could potentially target PD-L1 at tumor sites.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"334 2","pages":"1621 - 1629"},"PeriodicalIF":1.5,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143481149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seyed Javad Seyedi, Ehsan Ebrahimibasabi, Mohammad Mahdi Shahidi
{"title":"Evaluating the effects of gamma radiation on boron carbide: dose-dependent changes in crystallinity and microstructure","authors":"Seyed Javad Seyedi, Ehsan Ebrahimibasabi, Mohammad Mahdi Shahidi","doi":"10.1007/s10967-024-09909-5","DOIUrl":"10.1007/s10967-024-09909-5","url":null,"abstract":"<div><p>In this study, boron carbide particles (10 to 20 µm) were irradiated with cobalt-60 at doses of 10, 50, 100, and 200 kGy. Comprehensive analyses using X-ray diffraction (XRD) and field emission scanning electron microscopy (FESEM) were conducted on samples before and after exposure. XRD results indicated a significant decrease in amorphization at 100 kGy, revealing a discernible crystalline structure. FESEM analysis showed that this dose also led to an increase in particle size and a reduction in shell-like peeling. These findings suggest that a 100 kGy dose enhances crystallinity and modifies the surface morphology of boron carbide.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"334 3","pages":"2211 - 2217"},"PeriodicalIF":1.5,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s10967-024-09909-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143707006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development of analytical method for zirconium determination in U–Pu–Zr alloy samples","authors":"Vivekchandra Guruprasad Mishra, Neetika Rawat, Uday Kumar Thakur, Ashwani Kumar, Kaity Santu","doi":"10.1007/s10967-024-09893-w","DOIUrl":"10.1007/s10967-024-09893-w","url":null,"abstract":"<div><p>The study focuses on developing a robust method for determining zirconium in U–Pu–Zr alloy samples, crucial for assessing fuel composition and ensuring uniformity. Using mandelic acid precipitation and spectrophotometric quantification with Arsenazo-III, the method achieves high sensitivity and reproducibility, crucial for handling microgram-levels of Pu. By optimizing conditions to maintain Pu in its + 3 oxidation state, interference during Zr precipitation is minimized. Comparative analyses with ICP-AES validate the accuracy and reliability of the results. This approach not only enhances analytical precision but also reduces radioactive waste, making it suitable for nuclear fuel characterization.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"334 1","pages":"535 - 540"},"PeriodicalIF":1.5,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s10967-024-09893-w.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143110173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Imran Ali, Gunel Imanova, Teymur Agayev, Anar Aliyev, Tonni Agustiono Kurniawan, Abdulrahman Bin Jumah
{"title":"Green and sustainable hydrogen production from methane and methane water mixture using aluminosilicate catalyst and gamma radiations","authors":"Imran Ali, Gunel Imanova, Teymur Agayev, Anar Aliyev, Tonni Agustiono Kurniawan, Abdulrahman Bin Jumah","doi":"10.1007/s10967-024-09899-4","DOIUrl":"10.1007/s10967-024-09899-4","url":null,"abstract":"<div><p>Hydrogen production was achieved by irradiating methane and methane-water mixtures at 300–873 K on aluminosilicate (Al–O–Si) surface with gamma radiations. Results with methane molecules were two times higher at 773 K i.e. an increase in G(H<sub>2</sub>) yields from 1.2 to 2.3 molecules/100 eV. The efficiency of energy transfer in Al–O–Si–methane system was less than in Al–O–Si–water system. The maximum amount of hydrogen produced was 65.0 × 10<sup>17</sup> molecules/g at 10 atm methane pressure, 773 K temperature, 8 h and 1.2 Gy/s radiation dose. The amount of hydrogen produced is quite good and the results may be used on a pilot scale.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"334 2","pages":"1533 - 1540"},"PeriodicalIF":1.5,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143481003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mounir Aït-Ziane, Edmond Dupuis, Hilde Loots, Leen Verheyen, Michel Bruggeman, Marielle Lecomte, Damien Braekers, Meriem Mezaguer-Lekouaghet, Zohra Lounis-Mokrani
{"title":"Radon measurements in drinking water: a comparison between different techniques","authors":"Mounir Aït-Ziane, Edmond Dupuis, Hilde Loots, Leen Verheyen, Michel Bruggeman, Marielle Lecomte, Damien Braekers, Meriem Mezaguer-Lekouaghet, Zohra Lounis-Mokrani","doi":"10.1007/s10967-024-09884-x","DOIUrl":"10.1007/s10967-024-09884-x","url":null,"abstract":"<div><p>Radon-222 concentrations in drinking water samples, collected from four sites, with known concentrations, located in Troine, Hoffelt and Hachiville (Luxembourg) and Sainte Adèle source (Belgium) have been found about 111.2, 90.4, 86.0, and 83.7 Bq l<sup>−1</sup> respectively. The samples have been analysed by six laboratories using gamma-ray spectrometry, emanometry and liquid scintillation counting. The performance of the participating laboratories and their measurements were evaluated with respect to the consensus value using statistical tests. The obtained results indicate that all measurement system used as well as methods to measure radon-222 in water are good and comply to the European directive.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"334 1","pages":"57 - 66"},"PeriodicalIF":1.5,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143109812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ho Manh Dung, Tran Quang Thien, Ho Van Doanh, Phonesavanh Lathdavong, Truong Truong Son, Tran Tuan Anh, Dao Van Hoang
{"title":"A dual method using SMELS for neutron flux self-monitoring and quality control in k0-NAA","authors":"Ho Manh Dung, Tran Quang Thien, Ho Van Doanh, Phonesavanh Lathdavong, Truong Truong Son, Tran Tuan Anh, Dao Van Hoang","doi":"10.1007/s10967-024-09890-z","DOIUrl":"10.1007/s10967-024-09890-z","url":null,"abstract":"<div><p>This study presents a dual method for neutron flux self-monitoring and quality control in the <i>k</i><sub>0</sub>-based neutron activation analysis (<i>k</i><sub>0</sub>-NAA) using the Synthetic Multi-Element Standards (SMELS). SMELS comprise three distinct types, designated as Type I for short-lived, Type II for medium-lived, and Type III for long-lived radionuclides, all of which are employed for validating the <i>k</i><sub>0</sub>-NAA. Each SMELS type incorporates assigned amounts of gold (Au) and can serve as a neutron flux monitor. The Au concentration was automatically integrated into k0-DALAT—a home made software to calculate the gold specific activity (<i>A</i><sub>sp,Au</sub>), thereby derivating of mass fractions of elements of interest in the <i>k</i><sub>0</sub>-NAA. Additionally, the assigned concentrations of other elements within SMELS were used for <i>k</i><sub>0</sub>-NAA quality control purpose. Replicate analyses of NIST-SRM-1633b (Coal Fly Ash) and NIST-SRM-679 (Brick Clay) by <i>k</i><sub>0</sub>-NAA showed determination up to 29 and 25 elements, respectively with deviations within 7%, of which <i>u</i>-scores were almost less than ∣2.58∣, except only for Na and Fe of all 2.99. It revealed that the dual method using SMELS for both neutron flux self-monitoring and quality control considered convenient and consistent in comparison with the results obtained by the conventional independent comparator method biased within 1%.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"334 1","pages":"49 - 56"},"PeriodicalIF":1.5,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143109247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The diffusion behavior of Re(VII) in bentonite with low porosity","authors":"Weitong Chen, Dongyang Chen, Xinyu Chen, Jintao Wang, Weiran Wang, Zhifen Wang","doi":"10.1007/s10967-024-09887-8","DOIUrl":"10.1007/s10967-024-09887-8","url":null,"abstract":"<div><p>The diffusion behavior of Re(VII) in bentonite with low porosity was investigated by the capillary method at different SO<sub>4</sub><sup>2−</sup> concentrations, dry densities, pH values and ionic strengths. The batch experiment results revealed that the <i>D</i><sub><i>a</i></sub> values decreased with increasing SO<sub>4</sub><sup>2−</sup> concentration and dry density. This is mainly due to CaSO<sub>4</sub> precipitation blocking pore water channels to form low-porosity bentonite, and the porosity of bentonite with low porosity decreases as the dry density increases. In contrast, the influence of pH on the diffusion behavior of Re(VII) is relatively small. Moreover, the <i>D</i><sub><i>a</i></sub> values increase as the ionic strength increases because the free water pore channels widen.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"334 1","pages":"525 - 533"},"PeriodicalIF":1.5,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143109106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Research progress on neutron depth profiling at China advanced research reactor","authors":"Caijin Xiao, Liang Zhao, Yonggang Yao, Xiangchun Jin, Yu Zhang, Guojian Guo","doi":"10.1007/s10967-024-09891-y","DOIUrl":"10.1007/s10967-024-09891-y","url":null,"abstract":"<div><p>A neutron depth profiling (NDP) system was established at a cold neutron beam of China Advanced Research Reactor (CARR). In the recent years, we have upgraded the CARR NDP facility and made considerable advancements in spectral deconvolution methodology and related experiments. In 2023 CARR has been operational for over 100 days, conducting various experiments utilizing the NDP apparatus. These experiments encompassed several objectives: measurement thin films thickness, Li transportation and distribution in cathode materials and B distribution in semiconductor materials.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"334 1","pages":"41 - 47"},"PeriodicalIF":1.5,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143109231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adsorption of aqueous uranium(VI) species on graphitic carbon nitride adsorbent (g-CNA): kinetic, isotherm and thermodynamic studies","authors":"A. Dhanasekaran, Ilaiyaraja Perumal","doi":"10.1007/s10967-024-09869-w","DOIUrl":"10.1007/s10967-024-09869-w","url":null,"abstract":"<div><p>A graphitic carbon nitride adsorbent (g-CNA) has been developed for the removal of uranium from water. Experiments revealed that g-CNA exhibited a U(VI) adsorption capacity of 312.5 mg g<sup>−1</sup>, reaching equilibrium within 30 min at pH 6.0. The Langmuir isotherm fit confirmed the monolayer U(VI) adsorption. Pseudo-second-order kinetics indicated that U(VI) and g-CNA concentrations influenced the reaction rate, with electrostatic interactions involved in the adsorption mechanism. Thermodynamic studies indicated spontaneous exothermic adsorption of U(VI) on g-CNA. The adsorption efficiency of g-CNA remained stable with the electrolytes, and the adsorbed U(VI) was removed with HCl, confirming its potential for U(VI) remediation.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"334 1","pages":"79 - 91"},"PeriodicalIF":1.5,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143109067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Distribution of 226Ra, 210Pb and 210Po in soil of a uranium mineralised region of Northern Karnataka, India","authors":"I. Yashodhara, K. Sudeep Kumara, N. Karunakara","doi":"10.1007/s10967-024-09880-1","DOIUrl":"10.1007/s10967-024-09880-1","url":null,"abstract":"<div><p>The activity concentrations of <sup>226</sup>Ra, <sup>210</sup>Pb, and <sup>210</sup>Po in soil samples were measured in the Gogi region of Yadgiri district, Karnataka, South India, which is a uranium mineralisation area with prospects for future mining. A total of 273 samples were analysed from 0–5, 5–15, and 15–30 km zones around Gogi, the common centre of all the zones. The activity concentrations of these radionuclides were similar to the global average values. A strong positive correlation was found between the activity concentration values of <sup>226</sup>Ra, <sup>210</sup>Pb and <sup>210</sup>Po. Negative correlations were found between the activity concentrations of these radionuclides and soil characteristics such as cation exchange capacity (CEC), organic matter content (OMC), and pH.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"334 1","pages":"303 - 314"},"PeriodicalIF":1.5,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143109128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}