Amna Saeed, Aisha Munawar, Irfan Ullah Khan, Rizwana Zahoor, Arjumand Iqbal Durrani, Muhammad Waqas Ishaq, Surriya Bibi
{"title":"Preparation of multifunctional protein-capped selenium nanoparticles for drug delivery","authors":"Amna Saeed, Aisha Munawar, Irfan Ullah Khan, Rizwana Zahoor, Arjumand Iqbal Durrani, Muhammad Waqas Ishaq, Surriya Bibi","doi":"10.1007/s10967-026-11103-8","DOIUrl":"10.1007/s10967-026-11103-8","url":null,"abstract":"<div><p>This study focuses on the development of drug-loaded and radiolabeled nanoparticles with high carrying capacity for applications in diagnostic imaging and chemotherapy. Stable selenium nanoparticles (SeNPs) with controlled size were synthesized through a redox reaction involving ascorbic acid and sodium selenite. Doxorubicin (DOX) was efficiently loaded onto bromelain-capped SeNPs (BR-SeNPs), achieving a loading efficiency of 86.7%. The morphology and physicochemical properties of BR-SeNPs and DOX-BR-SeNPs were characterized using UV–visible spectrophotometry, dynamic light scattering (DLS), Fourier transform infrared (FTIR) spectroscopy, and zeta potential analysis. Radiolabeling of DOX-BR-SeNPs with ⁹⁹ᵐTc yielded an efficiency of ≥91 ± 2%. SPECT imaging in an animal model revealed considerable uptake in the liver, heart, and bladder. Collectively, these findings demonstrate that DOX-BR-SeNPs constitute a promising nanocarrier system for both diagnostic imaging and targeted drug delivery.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"335 9","pages":"6217 - 6228"},"PeriodicalIF":1.7,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149023064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yipeng Zhou, Guangrong Li, Kai Zhao, Zhanxue Sun, Suwen Zhu, Pingchao Ke, Lingling Xu, Jian Wang
{"title":"CO2 alteration in sandstone-type uranium ore during in-situ leaching: a case study from Mengqiguer deposit in Northwest China","authors":"Yipeng Zhou, Guangrong Li, Kai Zhao, Zhanxue Sun, Suwen Zhu, Pingchao Ke, Lingling Xu, Jian Wang","doi":"10.1007/s10967-026-11086-6","DOIUrl":"10.1007/s10967-026-11086-6","url":null,"abstract":"<div><p>The influence of CO<sub>2</sub> fluid on the element migration in rocks is a hot long-term argumentative issue. Mengqiguer sandstone type uranium deposit among which the ore were calcite‐cemented is one of the main uranium producers in china. This deposit is using in-situ neutral (CO<sub>2</sub> + O<sub>2)</sub> leaching process because of conventional leaching process (acid and alkaline) would cause blockage. With leaching progress going, blockage still occurred, which probably is caused by CO<sub>2</sub> reaction with calcium‐cemented uranium ore. That makes the uranium leaching factory a huge artificial laboratory that may reveal the effect of CO<sub>2</sub> fluid on elemental behavior. Polarizing microscope, field emission scanning electron microscope, electron probe, polycrystalline X‐ray diffraction, X‐ray fluorescence spectrometer and in-situ laser ablation inductively coupled plasma mass spectrometry were used in this study. The result showed that the gangue minerals in ore are quartz, feldspar, kaolinite and calcite, the first three of which are relative stable during leaching, however calcite changes obviously. The surface of the calcite after leaching is obviously rougher. In-situ geochemical analysis on the calcite illustrated that the relative contents of U and Sr decrease, and the contents of La, Ce, Nd, Sm, Gd, Pb, Lu increased. In addition, fractionation of heavy rare earth elements in the leached calcite is obviously higher than that in the un-leached. After leaching, Ce depletion in calcite is more obvious. After all, calcite has been unevenly dissolved in the whole leaching process, which provides the possibility for the evolution from calcareous cementation to argillaceous cementation.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"335 9","pages":"6067 - 6095"},"PeriodicalIF":1.7,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149023182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mona Maghsoudlou, Katalin Zsuzsanna Szabó, Judith Pena Dembo, Gabriel Iklaga, Péter Völgyesi, Csaba Szabó
{"title":"Influence of soil physicochemical properties on the distribution and variability of 137Cs activity concentrations in urban soils of Ózd, Hungary","authors":"Mona Maghsoudlou, Katalin Zsuzsanna Szabó, Judith Pena Dembo, Gabriel Iklaga, Péter Völgyesi, Csaba Szabó","doi":"10.1007/s10967-026-11093-7","DOIUrl":"10.1007/s10967-026-11093-7","url":null,"abstract":"<div><p>Urban soils exhibit substantial heterogeneity in their physicochemical properties influencing the sequestration of <sup>137</sup>Cs. This study investigates the distribution of <sup>137</sup>Cs in urban soils from Ózd, Hungary, and its relationship with soil properties using multivariate statistical analysis. The activity concentrations of <sup>137</sup>Cs were measured by gamma-ray spectrometry with well-type HPGe detector and ranged from below detection limit (DL = 0.3 Bq kg⁻<sup>1</sup>) to 19.3 ± 0.5 Bq kg⁻<sup>1</sup>, indicating distinct spatial variability. Ammonium and silt content of the studied urban soils were identified as the primary variables, together explaining 45% of <sup>137</sup>Cs variability. These results demonstrate that the interplay between ionic exchange and sorption onto fine-grained soil fractions controls <sup>137</sup>Cs retention, providing a framework for understanding radionuclide fate in disturbed urban soils.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"335 9","pages":"6045 - 6065"},"PeriodicalIF":1.7,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s10967-026-11093-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149023192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Riham A. Abou-Lilah, H. A. Elsanafeny, Abeer E. Kasem
{"title":"Separation of cesium and strontium from real radioactive waste solutions using a high-efficiency cobalt aluminum silico tungstate: batch and column studies","authors":"Riham A. Abou-Lilah, H. A. Elsanafeny, Abeer E. Kasem","doi":"10.1007/s10967-026-11115-4","DOIUrl":"10.1007/s10967-026-11115-4","url":null,"abstract":"<div><p>An advanced inorganic cobalt aluminum silico tungstate (CoAlSiW) sorbent was successfully synthesized and subsequently applied for the selective elimination of radioactive cesium and strontium ions from real liquid radioactive waste streams. CoAlSiW was characterized using diverse analytical techniques to reveal its structure, surface morphology, and physicochemical features. Studies on batch adsorption were conducted to evaluate the impacts of pH, contact time, initial ion concentration, and temperature on the sorption performance. The adsorption of Cs(I) and Sr(II) follows Freundlich isotherm model, confirming heterogeneous surface characteristics and favorable multilayer sorption behavior. According to thermodynamics, the process is spontaneous and energetically favorable. Importantly, the impact of gamma irradiation was evaluated, confirming the material’s high radiation stability and resistance, with no significant loss of sorption efficiency. Dynamic column breakthrough experiments further highlighted high sorption capacities of 78 mg g<sup>−1</sup> for Sr(II) and 72 mg g<sup>−1</sup> for Cs(I). The applicability of CoAlSiW for real radioactive waste treatment was confirmed by its high removal efficiency toward <sup>137</sup>Cs (92.6%) and a decontamination factor exceeding 13.3. Consequently, separation of radioactive cesium from liquid radioactive waste streams is recommended due to its significant radiological hazard, long half-life, and high mobility in the environment.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"335 9","pages":"6241 - 6256"},"PeriodicalIF":1.7,"publicationDate":"2026-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149023072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yangchun Chen, Jianjia Jiang, Ping Yuan, Jianwei Chen, Ruozhu Dai
{"title":"Kinetic modeling of [18F]FDG myocardial metabolism: elucidating the mechanistic superiority of insulin loading in viability assessment","authors":"Yangchun Chen, Jianjia Jiang, Ping Yuan, Jianwei Chen, Ruozhu Dai","doi":"10.1007/s10967-026-11100-x","DOIUrl":"10.1007/s10967-026-11100-x","url":null,"abstract":"<div><p>This study investigates the mechanism by which insulin loading enhances myocardial [<sup>18</sup>F]fluorodeoxyglucose ([<sup>18</sup>F]FDG) uptake compared to glucose loading. Using dynamic positron emission tomography and two-compartment irreversible kinetic modeling, 18 patients with ischemic heart disease were analyzed. Results demonstrate that insulin significantly increases the net influx rate (<i>Ki</i>) by accelerating blood-to-tissue transport (<i>K</i>1), while concurrently reducing tracer efflux (<i>k</i>2) and phosphorylation (<i>k</i>3). These findings provide a quantitative metabolic basis for the clinical superiority of insulin-enhanced imaging in detecting viable myocardium.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"335 9","pages":"6209 - 6216"},"PeriodicalIF":1.7,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149023112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Constraints of the uranium mineralization process of the Longchuanjiang basin, Western Yunnan, China: indications from mineralogical and geochemical evidence","authors":"Yongqun Tang, Jianjun Zhang, Min Shen, Ting Chen, Zeyi Chen, Kuanxin Huang, Donglin Xin","doi":"10.1007/s10967-026-11091-9","DOIUrl":"10.1007/s10967-026-11091-9","url":null,"abstract":"<div><p>A new sandstone-type uranium deposit was discovered in the Longchuanjiang Basin as uranium exploration continued. This article employs mineralogical and geochemical techniques to investigate the paleoenvironment, provenance, and tectonic setting of the newly identified mineral deposit while also examining its mineralization process. The Zr, ICV, and Zr/Sc-Th/Sc diagrams suggest that the Mangbang Formation has experienced multiple sedimentary cycles. The δCe-δEu, δCe-∑REE, and δCe-(Dy/Sm)<sub>N</sub> diagrams of the samples suggest that the chemical composition of the samples was marginally influenced by diagenesis, making them suitable for the investigation of paleoenvironments and provenance. The Sr, CIA, CIA<sub>corr</sub>, Rb/Sr, V/Cr, U/Th, (Cu+Mo)/Zn, and Ni/Co ratios indicate that the Mangbang Formation exhibits oxidative conditions, with certain portions transitioning to oxidation–reduction conditions and freshwater deposits in a warm and humid environment. Al<sub>2</sub>O<sub>3</sub>/TiO<sub>2</sub>, TiO<sub>2</sub>/Zr ratios, and Co/Th-La/Sc, La/Th-Hf, REE-La/Yb, SiO<sub>2</sub>-K<sub>2</sub>O/Na<sub>2</sub>O, Fe<sub>2</sub>O<sub>3</sub><sup>T</sup>+MgO-TiO<sub>2</sub>, Th-Co-Zr/10, and Th-Sc Zr/10 diagrams indicate the provenance of the Mangbang Formation is a mixture of felsic igneous rocks and granite, within an active continental margin setting associated with the closure of the Paleo-Tethys Ocean. During the sedimentary stage, there was pre-enrichment of uranium in the Mangbang Formation. The pre-enrichment of uranium is similar to that of Cd and Mo and is related to oxidation–reduction conditions and the clay minerals, but different from Ga. During the post-sedimentary stage, the uranium and oxygen-rich water migrate along the strata, activating the pre-enriched uranium and ultimately reducing and precipitating near the oxidation–reduction front. Through the ongoing processes of oxidation, migration, and precipitation, uranium accumulates and ultimately forms sandstone-type uranium deposits that can be industrially mined.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"335 9","pages":"6111 - 6127"},"PeriodicalIF":1.7,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149023110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Selective electrochemical removal of radium-226 and radium-228 from NORM-contaminated oilfield scales using functionalized graphene oxide electrodes: thermodynamic insights into Ba–Ra co-precipitation in high-salinity brines","authors":"Mostafa A. Algrifi","doi":"10.1007/s10967-026-11110-9","DOIUrl":"10.1007/s10967-026-11110-9","url":null,"abstract":"<div><p>Naturally occurring radioactive material (NORM), particularly Ra-226 and Ra-228, accumulates in oil-production scales and associated brines, creating radiological, environmental, and waste-management challenges. Radium removal from high-salinity systems is complicated by competition from Ba<sup>2+</sup>, Sr<sup>2+</sup>, and Ca<sup>2+</sup> and by sulfate-driven co-precipitation. Scale leachates were treated in synthetic brines up to 85 g/L total dissolved solids using functionalized GO-coated titanium electrodes in a batch electrochemical reactor. The effects of pH, salinity, applied potential, contact time, initial radium activity, and barium concentration were examined. Ra-226 and Ra-228 were quantified by HPGe gamma spectrometry using geometry- and density-matched calibration and equilibrium controls, and aqueous speciation and precipitation tendencies were modeled in PHREEQC. Under the optimized operating condition (pH 11.3, 2.5 V, 90 min), apparent removal efficiencies were 83.1% for Ra-226 and 79.3% for Ra-228, with distribution coefficients of 3.1 × 10^4 and 2.2 × 10^4 mL/g, respectively. Because Ra-226 and Ra-228 are chemically identical, the consistently lower Ra-228 values are treated as the more conservative estimate of radium removal. The electrode retained 90.8% regeneration efficiency after five cycles. At 250 mg/L Ba<sup>2+</sup>, modeling and experiments indicated that approximately 61% of apparent radium loss was attributable to Ba-Ra sulfate co-precipitation rather than electrode selectivity alone. Functionalized GO electrodes are potential selective and low sludge radium-control units in high-salinity oilfield systems. Co-precipitation with barium is however a large controlling process that needs to be distinguished from the actual electrochemical uptake and should not be overlooked when interpreting the removal efficiencies.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"335 9","pages":"6257 - 6269"},"PeriodicalIF":1.7,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149023180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Isaac W. Haynes, Charles M. Folden III, Iain May, Nathan C. Smythe
{"title":"155Eu analysis-extending the timeline of fission product measurement from separated element samples","authors":"Isaac W. Haynes, Charles M. Folden III, Iain May, Nathan C. Smythe","doi":"10.1007/s10967-026-11120-7","DOIUrl":"10.1007/s10967-026-11120-7","url":null,"abstract":"<div><p>As a high mass ‘wing’ fission product, the cumulative fission yield (CFY) of <sup>156</sup>Eu varies both with incident neutron energy and actinide isotope undergoing fission. Fission product <sup>155</sup>Eu should yield comparable information to that of <sup>156</sup>Eu long after this shorter half-life radioisotope has decayed (half-life of 4.75 years versus 15.19 days). In this context a series of solid Eu<sub>2</sub>O<sub>3</sub> mounts previously prepared for the measurement of <sup>156</sup>Eu have been reanalyzed for <sup>155</sup>Eu. Samples generated from the separation of europium from dissolved Highly Enriched Uranium (HEU) targets irradiated by thermal neutrons were used for technique development, with gamma-ray spectrometry proving to be an effective measurement technique. Utilizing this method two complimentary analyses paths were developed and then successfully applied to the measurement of sample sets where either the incident neutron and/or actinide fuels were varied. As would be expected, if the measurements were accurate and precise, <sup>155</sup>Eu fission yields varied in a predictable fashion with both neutron energy and actinide fuel. As further validation of the technique, the increased perturbation away from thermal fission yields as the cumulative fission yield mass chain increases was also observed (153<155<156). This was evidenced through comparison with prior analysis results for <sup>153</sup>Sm and <sup>156</sup>Eu. <sup>155</sup>Eu can thus be measured with a high degree of confidence in samples where both these shorter half-life radioisotopes have decayed.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"335 9","pages":"6271 - 6279"},"PeriodicalIF":1.7,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s10967-026-11120-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149023065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Huaidan Zhang, Yalong Ma, Yi Yang, Kim Dowling, Miao Chen
{"title":"Impact of environmental changes on uranium uptake by ferrihydrite synthesized from mine tailing leachate and its stability study","authors":"Huaidan Zhang, Yalong Ma, Yi Yang, Kim Dowling, Miao Chen","doi":"10.1007/s10967-026-11092-8","DOIUrl":"10.1007/s10967-026-11092-8","url":null,"abstract":"<div><p>Exposure to uranium poses significant environmental and health risks, with remediation being particularly challenging in acidic, aerobic environments. Uranium transformation is closely linked to iron minerals via adsorption and co-precipitation. In this study, ferrihydrite (Fh-LS) was synthesized from mine tailing leachate via bioleaching followed by precipitation, presenting a potential approach that reuse mining waste. Compared to pure ferrihydrite, Fh-LS demonstrated enhanced uranium adsorption capacity, reaching 195.6 mg/g at pH 5.5 and 30 °C, and maintained stability over extended periods. FT-IR revealed that phosphate species in Fh-LS contributed to enhanced uranium uptake. Kinetics and isotherm analysis indicated that this adsorption process involves both physical and chemical interactions, occurring on a heterogeneous surface with varying affinities—supporting the potential for multilayer adsorption. Environmental factors including pH, coexisting ions, ion strength and temperature were investigated for their influence on uranium uptake and retention. U adsorption was impaired at pH < 4 but remained high above this threshold for 1 year. Higher amount of U retained in solid during desorption than that in adsorption at the same pH, which highlights irreversibility of the U adsorption. Most anions, particularly PO<sub>4</sub><sup>3−</sup> and AsO<sub>4</sub><sup>3−</sup>, exhibited a positive effect on uranium uptake and stability, whereas most of cations tend to negative impact, with Fe<sup>3+</sup> being a notable exception. These findings help develop low-cost, site-adaptable remediation strategies in uranium-contaminated mining areas and offer insights into uranium mobility in acidic, aerobic conditions that underpins fundamental processes key to the mitigation of uranium contamination in mining sites.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"335 9","pages":"6169 - 6185"},"PeriodicalIF":1.7,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s10967-026-11092-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149023071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Synergistic enhancement of strontium extraction by open-chain polyether ligands in [Cnmim][NTf2] ionic liquids: a combined experimental and theoretical study","authors":"Chuanqi Gu, Ying Dai, Qifeng Lai, Xing Zhong, Zhuyao Li, Qinqin Tao","doi":"10.1007/s10967-026-11109-2","DOIUrl":"10.1007/s10967-026-11109-2","url":null,"abstract":"<div><p>The efficient separation of strontium from high-level liquid waste is crucial for nuclear waste management. This study investigates the synergistic enhancement of Sr<sup>2+</sup> extraction using two open-chain polyether ligands, BPht-14 and BPPT-14, by replacing chloroform with imidazolium-based ionic liquids [C<sub>n</sub>mim][NTf<sub>2</sub>] (n = 4, 6, 8). The effects of pH, contact time, initial concentration, temperature, and IL alkyl chain length on extraction performance were systematically evaluated. The results demonstrate significant enhancement in IL systems, with BPPT-14 achieving 95.2% extraction efficiency in [C₄mim][NTf<sub>2</sub>], compared to 84% in CHCl<sub>3</sub>. The extraction followed pseudo-second-order kinetics and was spontaneous and exothermic. Selectivity studies revealed improved separation factors for Sr<sup>2+</sup> over coexisting ions, with Sr/Cs increasing from 1.7 to 6.07. DFT calculations further suggested that the ionic-liquid systems favor Sr<sup>2+</sup> extraction mainly through a thermodynamically favorable cation-exchange pathway, while differences in ionic-liquid polarity help explain the alkyl-chain-length dependence of extraction performance. This work provides a useful basis for the development of ionic-liquid-based systems for efficient and selective Sr<sup>2+</sup> separation.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"335 9","pages":"6197 - 6207"},"PeriodicalIF":1.7,"publicationDate":"2026-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149023062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}