Journal of Cluster Science最新文献_第9页

Structural, Surface Interactions, Physicochemical, and Molecular Docking Evaluation of a New Hybrid 4-Chloroanilinium Trichloromercurate (II) Hybrid Material 新型 4-氯苯胺三氯化脲（II）杂化材料的结构、表面相互作用、物理化学和分子对接评估

IF 2.8 4区化学

Journal of Cluster Science Pub Date : 2024-04-06 DOI: 10.1007/s10876-024-02596-y

{"title":"Structural, Surface Interactions, Physicochemical, and Molecular Docking Evaluation of a New Hybrid 4-Chloroanilinium Trichloromercurate (II) Hybrid Material","authors":"","doi":"10.1007/s10876-024-02596-y","DOIUrl":"https://doi.org/10.1007/s10876-024-02596-y","url":null,"abstract":"<h3>Abstract</h3> Using the slow evaporation process, we successfully synthesized a novel hybrid material, (C6H7ClN)[HgCl3], which was subsequently characterized through various physicochemical methods. The crystal structure was determined within the triclinic system, specifically in space group P-1. The packing arrangement exhibited alternating di-trichloromercurate (II) (C6H7ClN)[HgCl3] dimers and 4-chloroanilinium cations. Hirshfeld surface analysis revealed that H...Cl interactions dominated, constituting 50.2% of the total interactions. Functional groups were assigned using IR spectroscopy, and the material’s classification as a wide forbidden band semiconductor was supported by an Eg value of 3.893 eV. The compound’s thermal stability was explored through TG-DTA analysis, and complex impedance spectroscopy aided in comprehending its electrical behavior. Molecular docking simulations demonstrated that the (C6H7ClN)[HgCl3] ligand effectively targeted active areas on bacterial and fungal proteins, suggesting its potential as a potent inhibitor against these microorganisms. These diverse findings highlight the multifaceted properties and potential applications of this intriguing novel hybrid material.","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140581947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Controlled Synthesis of Flower-Like TiO2 Nanosheets with Enhanced Photocatalytic Performance 可控合成具有增强光催化性能的花朵状二氧化钛纳米片

IF 2.8 4区化学

Journal of Cluster Science Pub Date : 2024-04-06 DOI: 10.1007/s10876-024-02599-9

{"title":"The Controlled Synthesis of Flower-Like TiO2 Nanosheets with Enhanced Photocatalytic Performance","authors":"","doi":"10.1007/s10876-024-02599-9","DOIUrl":"https://doi.org/10.1007/s10876-024-02599-9","url":null,"abstract":"<h3>Abstract</h3> Exploring inorganic flower-like nanosheets is of increasing interest not only for fundamental research, but also for development of devices due to their good chemical stability, versatility, and high surface-to-volume ratio. In this work, flower-like TiO2 nanosheets (FTN) are successfully synthesized by a facile hydrothermal method. Notably, a series of single-factor experiments are carried out to drive multiple functional components in order to integrate into a single flower-like nanostructure perfectly. In addition, these experimental results further reveal that alcohol/glycerol molar ratio acts in a vital role for preparing optimal flower-like morphology and structure of TiO2. Furthermore, the photodegradation pathways and mechanism of Levofloxacin (LVOF) by FTN are shown according to photodegradation intermediates of LVOF, trapping experiments, and ligand-to-metal charge transfer (LMCT) sensitizing effect. Therefore, the present work not only demonstrates the controlled synthesis of flower-like TiO2 nanosheets, but also provides a guide for constructing other inorganic flower-like nanosheets or TiO2-based photocatalysts with optimal morphology, structure and photocatalytic performance.","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140582050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

pH-Sensitive Stimulus Responsive ZIF-8 Composites Nanoparticles Coated with Folic Acid-Conjugated Chitosan for Targeted Delivery of Curcumin 叶酸共轭壳聚糖包覆的 pH 值敏感型刺激响应 ZIF-8 复合纳米粒子用于靶向输送姜黄素

IF 2.8 4区化学

Journal of Cluster Science Pub Date : 2024-04-06 DOI: 10.1007/s10876-024-02602-3

{"title":"pH-Sensitive Stimulus Responsive ZIF-8 Composites Nanoparticles Coated with Folic Acid-Conjugated Chitosan for Targeted Delivery of Curcumin","authors":"","doi":"10.1007/s10876-024-02602-3","DOIUrl":"https://doi.org/10.1007/s10876-024-02602-3","url":null,"abstract":"<h3>Abstract</h3> Zeolitic imidazolate framework-8 (ZIF-8) is a promising material for drug delivery, but its poor stability limits its wide application. In this work, homogeneous dodecahedral ZIF-8 was prepared by the room-temperature solution stirring method, and to improve the stability of ZIF-8, ZIF-8@mSiO2 and DZIF-8 (ZIF-8 after calcination) @PMO composites with the core-shell structure were obtained using mesoporous silica (mSiO2) and periodic mesoporous organic silica (PMO) coatings. Folic acid-coupled chitosan (CS-FA) was modified on nanoparticles, and curcumin (CUR) was used as a model anti-tumor drug to obtain the drug delivery systems with targeting and pH stimulation response: ZIF-8@mSiO2@CUR@CS-FA and DZIF-8@PMO@CUR@CS-FA, which exhibited good dispersion and high drug loading capability. In addition, we used the MTT assay to assess the cytotoxicity of the drug-carrying systems and selected human cervical cancer cells (Hela) as model cells. The results of the in vitro experiments suggested that the final CUR-loaded drug delivery systems had significantly increased anticancer efficiency compared with the free drug CUR, which improved the therapeutic effect of the hydrophobic CUR on tumors. In conclusion, the pH-responsive nanocarriers provided potential for the targeted delivery of anticancer medication, resulting in a platform for drug-controlled release and cancer therapy.","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140582038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Silver-Graphene Oxide-Cobalt Oxide Nanocomposite on Cytotoxic Levels in MRC-5 and HepG2 Cell Lines and Molecular Docking Studies 银-氧化石墨烯-氧化钴纳米复合材料对 MRC-5 和 HepG2 细胞系细胞毒性水平的影响及分子对接研究

IF 2.8 4区化学

Journal of Cluster Science Pub Date : 2024-04-06 DOI: 10.1007/s10876-024-02604-1

{"title":"Effect of Silver-Graphene Oxide-Cobalt Oxide Nanocomposite on Cytotoxic Levels in MRC-5 and HepG2 Cell Lines and Molecular Docking Studies","authors":"","doi":"10.1007/s10876-024-02604-1","DOIUrl":"https://doi.org/10.1007/s10876-024-02604-1","url":null,"abstract":"<h3>Abstract</h3> The cytotoxic properties of cobalt oxide (Co3O4) nanoparticles (NPs), in addition to graphene oxide (GO)-Co3O4 and silver (Ag)-GO-Co3O4 nanocomposites (NCs), were evaluated against both human healthy lung fibroblast (MRC-5) and hepatocellular carcinoma (HepG2) cell lines utilizing the XTT assay. The investigation revealed that synthesized Co3O4 NPs and NCs (GO-Co3O4 and Ag-GO-Co3O4) elicited significant cytotoxic responses in MRC-5 and HepG2 cell lines in a concentration-dependent manner. Through molecular docking analyses, it was observed that all fabricated nanomaterials exhibited DNA recognition via minor groove binding, with molecular affinities ranging from − 4.82 to -11.66 kcal/mol. Furthermore, the docking outcomes illustrated that the angular conformations of GO-Co3O4 and Ag-GO-Co3O4 conferred ‘shape-selective’ characteristics as DNA minor groove binders, leading to heightened cytotoxicity, particularly in the HepG2 cell line compared to the normal MRC-5 cell line.","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140582037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reactivity of 5-Methylpyridyl-2-Selenolate With Platinoid Metal Precursors: Isolation of Tri and Hexanuclear Complexes via Se-Se and Se-C Bond Cleavage 5-Methylpyridyl-2-Selenolate 与铂类金属前体的反应性：通过 Se-Se 和 Se-C 键裂解分离三核和六核配合物

IF 2.8 4区化学

Journal of Cluster Science Pub Date : 2024-04-06 DOI: 10.1007/s10876-024-02606-z

{"title":"Reactivity of 5-Methylpyridyl-2-Selenolate With Platinoid Metal Precursors: Isolation of Tri and Hexanuclear Complexes via Se-Se and Se-C Bond Cleavage","authors":"","doi":"10.1007/s10876-024-02606-z","DOIUrl":"https://doi.org/10.1007/s10876-024-02606-z","url":null,"abstract":"<h3>Abstract</h3> A series of palladium (II) and platinum (II) selenolate complexes have been isolated depending upon the nature of the phosphine ligand. The substitution reaction of [PdCl2(PPh3)2] with two equivalents of NaSeC5H3(5-Me)N resulted in the hexanuclear complex [Pd6Br0.87Cl1.13{2-SeC5H3(5-Me)N2}2(PPh3)6] (1a) whereas a chelated compound [Pt{κ-Se, κ-N: SeC5H3(5-Me)N}{SeC5H3(5-Me)N}(PPh3)] (1b) has been obtained in the case of [PtCl2(PPh3)2]. However, chelated phosphine as an ancillary ligand with a similar reaction by using [PtCl2(P∩P)] (P∩P = dppm, dppe) yielded cis-configured monomer [Pt{2-SeC5H3(5-Me)N}2(P∩P)]. The trinuclear complexes [M3(µ-Se)3(dppp)3]2+ [M = Pd (2d), Pt (2e)] were isolated by reactions of [MCl2(dppp)] (M = Pd, Pt) with NaSeC5H3(5-Me)N via facile cleavage of Se-C bond in presence of chlorinated solvents. All the synthesized complexes have been characterized by elemental analyses, 1H, 31P{1H}, 77Se{1H} NMR spectroscopy. The molecular structure of complexes [Pd6Br0.87Cl1.13{2-SeC5H3(5-Me)}2(PPh3)6] (1a) and [Pt{2-SeC5H3(5-Me)N}2(dppm)].C6H5CH3 (2a) were determined by single crystal X-ray diffraction analyses.","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140582041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fluorescent Carbon Dots from Cumin Seeds: Preparation, Characterization and In Vitro Biocompatibility Test for Cell Imaging Application 小茴香种子中的荧光碳点：用于细胞成像的制备、表征和体外生物相容性测试

IF 2.8 4区化学

Journal of Cluster Science Pub Date : 2024-04-06 DOI: 10.1007/s10876-024-02609-w

{"title":"Fluorescent Carbon Dots from Cumin Seeds: Preparation, Characterization and In Vitro Biocompatibility Test for Cell Imaging Application","authors":"","doi":"10.1007/s10876-024-02609-w","DOIUrl":"https://doi.org/10.1007/s10876-024-02609-w","url":null,"abstract":"<h3>Abstract</h3> Carbon dots (CDs) are a new type of nanomaterial with great potential in bioimaging, biosensing, and drug delivery. In this study, novel CDs were prepared from cumin seeds (Cuminum cyminum L) by pyrolysis. The pyrolysis method and several extraction steps were optimized to fabricate CDs from cumin seed. The size, structure, chemical composition, and photoluminescence properties of the CDs were characterized using size analyzer, zeta sizer, TEM, SEM, EDX, UV-Vis, fluorescence spectroscopy, and FTIR. The influence of the CDs on cell viability was investigated in A549, 3T3, and MCF-7 cell lines using MTT assay. The cancer cell imaging potential of the CDs was assessed using fluorescence microscopy. The results showed that the CDs with a mean diameter of 13.4 ± 3.7 nm and zeta potential of -23.3 ± 7.5 mv can be obtained by the pyrolysis of cumin seed powder. The obtained CDs exhibited strong and unique fluorescence properties when they were excited at different wavelengths, particularly 350 nm. The CDs were highly stable over time, and their fluorescence properties remained unchanged after three months. Apart from the physicochemical properties of the CDs, cell viability assays showed that these CDs were non-toxic to A549, MCF-7, and 3T3 cells, over 90% of the cells were viable after 24 h, even at the highest concentration (1000 µg/ml). The CDs successfully penetrated the MCF-7 cells as revealed by fluorescent images. Taken together, the fluorescent CDs derived from cumin seeds through the presented facile technique indicated excellent and stable fluorescence properties. In addition, these CDs were highly biocompatible in vitro and could be a potential option for theragnostic applications.","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140581941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimization, Characterization and In-Vitro Cellular Uptake of Donepezil-Loaded NanoCrystVesicles 多奈哌齐负载型纳米晶体囊泡的优化、表征和体外细胞吸收

IF 2.8 4区化学

Journal of Cluster Science Pub Date : 2024-04-06 DOI: 10.1007/s10876-024-02608-x

{"title":"Optimization, Characterization and In-Vitro Cellular Uptake of Donepezil-Loaded NanoCrystVesicles","authors":"","doi":"10.1007/s10876-024-02608-x","DOIUrl":"https://doi.org/10.1007/s10876-024-02608-x","url":null,"abstract":"<h3>Abstract</h3> The prevalence of Alzheimer's disease (AD) in developed and developing nations is increasing day by day. The monotherapy doesn't fit best for AD due to chronic treatment. This work aimed to prepare the liposomes coloaded with Donepezil and pine oil intended for adjuvant effect. Pine oil was selected due to its amyloid disaggregation and AChE inhibition property. The thin film hydration method with sonication was selected to formulate ultra-small-sized unilamellar vesicles. Apart from this formulated vesicle were subject to particle size, morphological, release, nasal ciliotoxicity and cellular uptake studies. The PDI, particle size, and zeta potential of the final egg lecithin-based liposome were found to be 0.19, 129 nm, and -27.5 mV, respectively, stable at 4° and 25°C. SEM microscopy of oil-loaded liposomes exhibits a crystalline cubic shape and is compared with alone drug-loaded liposomes that are spherical. AChE inhibition activity was found to be higher in combination when compared with others. The prepared liposomes were safe when studied for nasal ciliotoxicity studies and rapid uptake by C6 cells with complete internalization. This study demonstrated the development and potential of the vesicular system that carries valuable characteristics and overcomes patient compliance concerns that prove to be novel therapeutics for managing AD. <h3>Graphical Abstract</h3> <img alt=\"\" src=\"https://static-content.springer.com/image/MediaObjects/10876_2024_2608_Figa_HTML.png\"/> ","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140582336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fabrication of a Fe3O4/CS/AgNPs Composite from Indigenous Iron Sand for Enhanced Methylene Blue Adsorption 利用本地铁砂制备用于增强亚甲基蓝吸附的 Fe3O4/CS/AgNPs 复合材料

IF 2.8 4区化学

Journal of Cluster Science Pub Date : 2024-04-05 DOI: 10.1007/s10876-024-02594-0

Rhaya Desinta Ningtyas, Demi Dama Yanti, Amalia Kurnia Amin, Abdul Aji

{"title":"Fabrication of a Fe3O4/CS/AgNPs Composite from Indigenous Iron Sand for Enhanced Methylene Blue Adsorption","authors":"Rhaya Desinta Ningtyas, Demi Dama Yanti, Amalia Kurnia Amin, Abdul Aji","doi":"10.1007/s10876-024-02594-0","DOIUrl":"https://doi.org/10.1007/s10876-024-02594-0","url":null,"abstract":"In this study, magnetite (Fe3O4) material was synthesized from natural iron sand and subsequently augmented with chitosan/silver nanoparticles (Fe3O4/CS/AgNPs) to serve as a methylene blue (MB) adsorbent. The Fe3O4/CS/AgNPs composite was prepared via co-precipitation method and confirmed by X-ray diffraction (XRD), vibrating sample magnetometry (VSM), Fourier transform infrared spectroscopy (FTIR), and field emission-scanning electron microscopy (FE-SEM). FE-SEM images revealed that Fe3O4 and Fe3O4/CS/AgNPs composites were octahedron and oval-shaped, respectively, with Ag particles evenly dispersed across the Fe3O4/CS surface. The VSM data disclosed that the saturation magnetization for the Fe3O4/CS/AgNPs adsorbent was 21.36 emu/g, and it could be effortlessly separated from the solution with the help of an external magnet. The kinetics and adsorption isotherms data for MB on the Fe3O4/CS/AgNPs composite correspond well with the pseudo-second-order kinetic model and Langmuir isotherm model. The maximum adsorption capacity for MB on the Fe3O4/CS/AgNPs adsorbent was 74.63 mg/g, and the percentage removal of MB could be maintained at 70.4% after five cycles of repetition. Overall, the Fe3O4/CS/AgNPs composite shows promise as a reliable adsorbent for eliminating MB from environments.","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140585805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of Box–Behnken Design to Optimize Visible-Light Degradation of 2,4-Dichlorophenoxyacetic Acid Using Hybrid CNQDs/CuBi2O4 Catalyst 应用盒式贝肯设计优化 CNQDs/CuBi2O4 混合催化剂在可见光下降解 2,4 二氯苯氧乙酸的过程

IF 2.8 4区化学

Journal of Cluster Science Pub Date : 2024-03-30 DOI: 10.1007/s10876-024-02590-4

Nguyen Thi Thanh Huong, D. Khanh, N. Vy, L. Khoa, Nguyen Ngoc Nghia, Nguyen Thi Kim Phuong

引用次数: 0

Hemocompatibility and Antioxidant Properties of Nano-Sized Barium Titanate in Cubic and Tetragonal System 立方和四方体系纳米级钛酸钡的血液相容性和抗氧化特性

IF 2.8 4区化学

Journal of Cluster Science Pub Date : 2024-03-30 DOI: 10.1007/s10876-024-02611-2

K. V. Ivanov, Yu. A. Filimonova, N. Sirotkin, A. Agafonov, S. B. Nazarov

引用次数: 0