Journal of Cluster Science最新文献

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Selenium Nanorods from Lawsonia inermis Flowers: Enhancing Anti-Diabetic Effects and Cognitive Function Via mTOR/Akt and BDNF/pTrKB/CREB Pathways in High Glucose-Induced Neuroblastoma SH-SY5Y Cells 荆芥硒纳米棒:通过mTOR/Akt和BDNF/pTrKB/CREB通路在高糖诱导的神经母细胞瘤SH-SY5Y细胞中增强抗糖尿病作用和认知功能
IF 3.6 4区 化学
Journal of Cluster Science Pub Date : 2025-06-02 DOI: 10.1007/s10876-025-02846-7
Shahanaj Ismail, Ramalingam Srinivasan, Ramamoorthy Kavitha, Natarajan Devarajan
{"title":"Selenium Nanorods from Lawsonia inermis Flowers: Enhancing Anti-Diabetic Effects and Cognitive Function Via mTOR/Akt and BDNF/pTrKB/CREB Pathways in High Glucose-Induced Neuroblastoma SH-SY5Y Cells","authors":"Shahanaj Ismail,&nbsp;Ramalingam Srinivasan,&nbsp;Ramamoorthy Kavitha,&nbsp;Natarajan Devarajan","doi":"10.1007/s10876-025-02846-7","DOIUrl":"10.1007/s10876-025-02846-7","url":null,"abstract":"<div><p>Cognitive impairment and brain cell death are linked to the harmful effects of high hyperglycemia. This work examines the antioxidant and cognitive-boosting properties of selenium nanorods derived from <i>Lawsonia inermis</i> (Henna) flower extract in protecting SH-SY5Y neuroblastoma cells from oxidative damage generated by high glucose (HG). The selenium nanorods (HF-SeNRs) were produced by employing the henna flower extract (HFE) as both a stabilizer and reductant. The pharmacokinetic behavior of the phytocompounds present in the HFE explored using computational approaches. The physico-chemicals properties of nanorods were then examined utilizing a range of spectral and microscopic methods, including FTIR, XRD, EDX, HR-TEM, DSC and FFT. HF-SeNRs, measuring 17–20 nm in size and having a rod-shaped structure, demonstrated notable antioxidant properties and effectively inhibited the acetylcholinesterase enzyme activity. Pre-treatment of SH-SY5Y cells exposed to high glucose with HF-SeNRs (at concentrations ranging from 6.25 to 25 µg/mL) resulted in a dose-dependent preservation of cell viability. This pre-treatment also postponed the onset of oxidative damage-induced mitochondrion-related impairment, DNA breakage, and programmed cell death. In addition, HF-SeNRs decreased the expression of cell death promotor proteins (p53, Bax, caspase 3) and increased the expression of the cell death inhibiting protein Bcl-2 in high glucose circumstances. They regulated the AKT/mTOR and BDNF/TrkB/CREB signaling pathways, which are linked to cellular development, proliferation, and cognitive function. HF-SeNRs showed potential in mitigating oxidative damage and cell death induced by high glucose exposure in SH-SY5Y cells. This was achieved by increasing antioxidant activity and modulating signaling proteins related to cell death and cognitive function.</p></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"36 4","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145141974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ellagic Acid-Wrapped Gold Nanoparticles: Evaluation of Antimicrobial, Antioxidant, Anti-Inflammatory, and Cytotoxicity Effects of KB Cells 鞣花酸包裹金纳米颗粒:KB细胞的抗菌、抗氧化、抗炎和细胞毒性作用的评价
IF 3.6 4区 化学
Journal of Cluster Science Pub Date : 2025-06-02 DOI: 10.1007/s10876-025-02852-9
Muskan Soni, Chinnasamy Ragavendran, Mohamed Imath, Salim Manoharadas, Ismini Nakouti
{"title":"Ellagic Acid-Wrapped Gold Nanoparticles: Evaluation of Antimicrobial, Antioxidant, Anti-Inflammatory, and Cytotoxicity Effects of KB Cells","authors":"Muskan Soni,&nbsp;Chinnasamy Ragavendran,&nbsp;Mohamed Imath,&nbsp;Salim Manoharadas,&nbsp;Ismini Nakouti","doi":"10.1007/s10876-025-02852-9","DOIUrl":"10.1007/s10876-025-02852-9","url":null,"abstract":"<div><p>The green synthesis of metal nanoparticles using plant-based molecules is gaining attention for its potential in biomedical applications. The aim of present study the eco-friendly synthesis of gold nanoparticles (AuNPs) using ellagic acid, a natural antioxidant, which acted as both reducing and capping agent. The successful synthesized ellagic acid-coated AuNPs (EA-AuNPs) was indicated by a colour change to dark brown and confirmed through UV-visible spectroscopy with a peak at 587.5 nm. Transmission electron microscopy (TEM) revealed long rod-shaped nanoparticles ranging from 50 to 70 nm in size, and energy-dispersive X-ray spectroscopy (EDX) confirmed the presence of Au, C, Cl, and N elements. Zeta potential analysis showed a stable surface charge of -17.7 mV. EA-AuNPs exhibited strong antibacterial activity, including a 37.26 ± 0.9 mm inhibition zone against <i>Klebsiella pneumoniae</i> at 100 µg/mL and minimum inhibitory concentration (MIC) values below 1 µg/mL against <i>Staphylococcus aureus</i>. The nanoparticles also demonstrated potent antioxidant activity, achieving 91% and 89% radical scavenging in DPPH and ABTS assays, respectively. Anti-inflammatory testing showed 78% membrane stabilization at 200 µg/mL. Moreover, cytotoxicity studies revealed that EA-AuNPs had an IC₅₀ of 59.58 µg/mL against oral epidermoid carcinoma (KB) cells. In-silico analysis also demonstrated a promising binding affinity of -7.3 kcal/mol with <i>Candida albicans</i>, suggesting notable antifungal properties. The present study highlights the multi-functional therapeutic potential of EA-AuNPs in oral health care, offering a biocompatible approach to combat microbial infections, oxidative stress, inflammation, and oral cancer. The integration of both in-vitro and in-silico results supports their future application in dental and oral medicine.</p></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"36 4","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145142031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structural, Electronic and Magnetic Properties of S 0/±8 and S8X0/± Clusters, X = (Sc-Ni) s0 /±8和S8X0/±簇的结构、电子和磁性能,X = (Sc-Ni)
IF 3.6 4区 化学
Journal of Cluster Science Pub Date : 2025-06-01 DOI: 10.1007/s10876-025-02842-x
Yamina Cheballah, Mohammed Ziane, Karima Cheballah
{"title":"Structural, Electronic and Magnetic Properties of S\u0000 0/±8\u0000 \u0000 and S8X0/± Clusters, X = (Sc-Ni)","authors":"Yamina Cheballah,&nbsp;Mohammed Ziane,&nbsp;Karima Cheballah","doi":"10.1007/s10876-025-02842-x","DOIUrl":"10.1007/s10876-025-02842-x","url":null,"abstract":"<div><p>The geometric, electronic and magnetic properties of neutral and charged S<span>(_{8}^{0/pm })</span> and S<span>(_{8})</span>X<span>(^{0/pm })</span>, X = (Sc-Ni), clusters have been investigated in the framework of the density functional theory, within the generalized gradient approximation for the exchange and correlation. Results indicate that the most stable structure of S<span>(_{8})</span> cluster is the D<span>(_{4d})</span> crown shaped geometry. The calculated values of the bond length, S-S-S angle, vibrational frequency and adiabatic ionization potential of S<span>(_{8})</span> cluster are found to be in good agreement with the available experimental data. Doping with a single X impurity is enough to change the structure of the sulfur cluster to a large extent. The X atom is always adsorbed in the center of the sulfur host. For all doped clusters, only three-dimensional low-energy isomers are found. The impact of transition-metal doping of sulfur clusters on the atomic structure, stability, and reactivity is determined through the analysis of the binding energy per atom and global reactivity indicators like the electronegativity and chemical hardness. All doped clusters show larger binding energies with respect to the pure one, indicating that doping could stabilize the S<span>(_8)</span> cluster, and enhances the thermodynamic stability of the host. According to the HOMO-LUMO gaps, the doped cluster S<span>(_8)</span>Fe could have interesting optical properties. Doping change the magnetic state and the magnetic moment distribution in the S<span>(_{8})</span> host. A completely quenched dopant magnetic moment is found in S<span>(_{8})</span>Sc<span>(^{-})</span>, S<span>(_{8})</span>Ti, S<span>(_{8})</span>V<span>(^{pm })</span>, and S<span>(_{8})</span>Co<span>(^{pm })</span>, while high spin magnetic moments are located on S<span>(_{8})</span>Cr<span>(^{0/-})</span>, S<span>(_{8})</span>Mn<span>(^{0/pm })</span>, and S<span>(_{8})</span>Fe<span>(^{0/-})</span> clusters. In order to explain the changes of the magnetic moments within doped clusters, partial densities of states are discussed in detail.</p></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"36 3","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145160571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of Cervical Cancer with Tumor Homing Peptide LyP-2 Functionalized Liposome Loaded with Cisplatin and Vorinostat 顺铂与伏立诺他负载肿瘤归巢肽LyP-2功能化脂质体治疗宫颈癌
IF 2.7 4区 化学
Journal of Cluster Science Pub Date : 2025-05-21 DOI: 10.1007/s10876-025-02827-w
Zuoping Li, Jiaru Zhang, Shiwan You, Jing Zhang, Zhenzhen Xie, Na Zhao, Shiguo Sun
{"title":"Treatment of Cervical Cancer with Tumor Homing Peptide LyP-2 Functionalized Liposome Loaded with Cisplatin and Vorinostat","authors":"Zuoping Li,&nbsp;Jiaru Zhang,&nbsp;Shiwan You,&nbsp;Jing Zhang,&nbsp;Zhenzhen Xie,&nbsp;Na Zhao,&nbsp;Shiguo Sun","doi":"10.1007/s10876-025-02827-w","DOIUrl":"10.1007/s10876-025-02827-w","url":null,"abstract":"<div><p>Neuropilin-1 (NRP-1) is overly expressed on the membrane of cervical cancer cells, which is indispensable for cell internalization. NRP-1 achieves the goal of targeting cervical cancer cells with tumor homing peptide (THPs) in C-terminal (CendR) pathway. By this feature, the ligand LyP-2 peptide of NRP-1 with high affinity (also containing CendR motif) was functionalized on the surface of liposome (Lipo@LyP-2) to mediate its tumor homing. Under TEM, Lipo@LyP-2 is a smooth global body, whose diameter was less than 200 nm. Lipo@LyP-2 showed enhanced cell uptake in cervical cancer cells associated with human papillomavirus type 16 (HPV16) by the Confocal laser scanning microscope (CLSM). In the MTT assay, Lipo@LyP-2/SAHA/CDDP loaded with cisplatin (CDDP) and vorinostat (SAHA) also showed significant toxicity via increasing pro-apoptotic factors and decreasing anti-apoptotic factors. In addition, Western blot assay found that SAHA enhanced the intra-tumoral level of MHC class I chain-associated protein A (MICA) in cervical cancer, thus enhancing the sensitivity of cervical cancer cells to cytolysis mediated by natural killer (NK) cells. These results strongly indicate that LyP-2 functionalized Lipo/SAHA/CDDP can improve the targeting of CDDP and SAHA to SiHa cells and improve the therapeutic efficiency.</p></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"36 3","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144108455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structural Isomers and Superatomic Character of the Smallest Endohedral Azafullerene U@C27N 最小内嵌氮杂烯的结构异构体及其超原子性质U@C27N
IF 2.7 4区 化学
Journal of Cluster Science Pub Date : 2025-05-17 DOI: 10.1007/s10876-025-02833-y
Zhenyao Shi, Xinde Li, Dongrun Sun, Peng Jin
{"title":"Structural Isomers and Superatomic Character of the Smallest Endohedral Azafullerene U@C27N","authors":"Zhenyao Shi,&nbsp;Xinde Li,&nbsp;Dongrun Sun,&nbsp;Peng Jin","doi":"10.1007/s10876-025-02833-y","DOIUrl":"10.1007/s10876-025-02833-y","url":null,"abstract":"<div><p>Endohedral metalloazafullerenes (EMAFs) and endohedral metalloborafullerenes (EMBFs) are nitrogen- and boron-doped carbon cages, respectively, with metallic species inside. Recent experiments have successfully synthesized U@C<sub>27</sub>B as the smallest EMBF. Herein, density functional theory (DFT) calculations were conducted to systematically investigate the possible structure of its corresponding EMAF analogue, U@C<sub>27</sub>N. By fully considering the relative energies at 0 K and entropy effect at high temperatures for all potential U@C<sub>27</sub>N isomers, we predicted U@<i>T</i><sub><i>d</i></sub>-C<sub>27</sub>N-[5,5,5] and U@<i>T</i><sub><i>d</i></sub>-C<sub>27</sub>N-[5,5,6] with different nitrogen doping positions as its two major isomers. The encapsulated U atom formally adopts the highest VI oxidation state, and is effectively stabilized by the strong covalent interactions with the cage. Holding an unpaired electron on the cage, U@C<sub>27</sub>N could easily dimerize. Interestingly, it maintains a superatomic state with a perfect closed-shell 1S<sup>2</sup>1P<sup>6</sup>1D<sup>10</sup>1F<sup>14</sup> electronic configuration by using 32 out of 35 valence electrons in both the monomers and dimers. The novel structures and good stability promise the possible synthesis of this smallest EMAF in the experiments.</p></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"36 3","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144073638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Elucidating the Structural Stability of the Ligand Protected Ag Nanoclusters with 5e-8e Valence Electrons 5e-8e价电子配体保护银纳米团簇结构稳定性的研究
IF 2.7 4区 化学
Journal of Cluster Science Pub Date : 2025-05-17 DOI: 10.1007/s10876-025-02838-7
Endong Wang, Yi Gao
{"title":"Elucidating the Structural Stability of the Ligand Protected Ag Nanoclusters with 5e-8e Valence Electrons","authors":"Endong Wang,&nbsp;Yi Gao","doi":"10.1007/s10876-025-02838-7","DOIUrl":"10.1007/s10876-025-02838-7","url":null,"abstract":"<div><p>The concept of superatoms has long been used as a guide to understand the stability of clusters. However, little work has been done to compare the structural stability of ligand-protected Ag nanoclusters with the same kernel using the superatom concept. In this study, we construct six clusters based on the same Ag<sub>13</sub> kernel, including 5<i>e</i> Ag<sub>17</sub>(SR)<sub>12</sub>, 6<i>e</i> Ag<sub>20</sub>(SR)<sub>14</sub>, 6<i>e</i> Ag<sub>18</sub>(SR)<sub>12</sub>, 7<i>e</i> Ag<sub>19</sub>(SR)<sub>12</sub>(DMPA)<sub>3</sub>, 7<i>e</i> Ag<sub>25</sub>(SR)<sub>18</sub>, and 8<i>e</i> [Ag<sub>25</sub>(SR)<sub>18</sub>]<sup>–</sup> (where R = -CH<sub>3</sub>, Methyl; DMPA = C<sub>6</sub>H<sub>16</sub>P<sub>2</sub>, 1,2-Bis(dimethylphosphino)ethane). The regulation of the valence electron count is achieved by varying the outer motifs—Ag(SR)<sub>2</sub>, Ag<sub>2</sub>(SR)<sub>3</sub>, Ag(SR)<sub>3</sub>, and Ag<sub>2</sub>(SR)<sub>4</sub>(DMPA)—which withdraw 1, 1, 2, and 2 valence electrons from the inner kernel, respectively. The results show that the 8<i>e</i> [Ag<sub>25</sub>(SR)<sub>18</sub>]<sup>–</sup> cluster, with its closed 1S<sup>2</sup>|1P<sup>6</sup> electron configuration, exhibits the least structural variation, a more balanced atomic charge distribution in the kernel Ag atoms, and a relatively large HOMO-LUMO gap. This work contributes to a better understanding of the superatom concept in the context of the structure of ligand-protected Ag nanoclusters.</p></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"36 3","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144073640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Design and Evaluation of Water-Responsive Polymer-Coated Zeolite as a Synergistic Antibacterial Carrier for Essential Oil Delivery 水响应型聚合物包膜沸石精油协同抗菌载体的设计与评价
IF 2.7 4区 化学
Journal of Cluster Science Pub Date : 2025-05-17 DOI: 10.1007/s10876-025-02826-x
Xinhui Peng, Yanshuang Shi, Shuai Cen, Minyue Jia, Qing Zhou, Weishuo Ren, Bingxuan Li, Guoqing Li, Yueyang Xie, Xingxing Dai, Xinyuan Shi
{"title":"Design and Evaluation of Water-Responsive Polymer-Coated Zeolite as a Synergistic Antibacterial Carrier for Essential Oil Delivery","authors":"Xinhui Peng,&nbsp;Yanshuang Shi,&nbsp;Shuai Cen,&nbsp;Minyue Jia,&nbsp;Qing Zhou,&nbsp;Weishuo Ren,&nbsp;Bingxuan Li,&nbsp;Guoqing Li,&nbsp;Yueyang Xie,&nbsp;Xingxing Dai,&nbsp;Xinyuan Shi","doi":"10.1007/s10876-025-02826-x","DOIUrl":"10.1007/s10876-025-02826-x","url":null,"abstract":"<div><p>Essential oil (EO), a promising natural antimicrobial agent, face challenges in therapeutic applications due to volatility and instability. This study presents a coated peppermint oil-zeolite composite (PO@zeolite) with dual-release functionality. Analysis of 14 zeolites revealed that the High Pressure-Ball-1 (HP-B-1) zeolite demonstrated optimal adsorption capabilities of 30.14% maximum loading, attributed to structural parameters including pore topology, surface area (&gt; 800 m²/g), and pore volume. Encapsulation through stirring processes achieved uniform EO and polymer distribution within zeolites, as confirmed by SEM and FTIR analyses. Tuning coating thickness enabled adjustable release: higher coating gain leads to more sustained release and less water-responsive burst release. Synergistic bacteriostatic effects between zeolite excipients and EOs enhanced antimicrobial efficacy against <i>Escherichia coli</i>, <i>Staphylococcus aureus</i>, and <i>Candida albicans</i> through adsorption mechanisms. This study demonstrates multifunctional material design concept for multifunctional carriers for economic EO delivery systems.</p></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"36 3","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144073636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eco-Friendly CuMoO4/Bi2S3 Nanocomposites: Superior Solar-Light Catalysts for Indigo Carmine Dye Degradation and Its Antibacterial Efficacy 环保CuMoO4/Bi2S3纳米复合材料:降解靛蓝胭脂红染料的光能催化剂及其抑菌效果
IF 2.7 4区 化学
Journal of Cluster Science Pub Date : 2025-05-17 DOI: 10.1007/s10876-025-02835-w
Ramasamy Govarthini, Shanmugam Vignesh, Elango Visithira, Govindasami Periyasami, Lalitha Gnanasekaran, Rajendran Ranjith, Thammasak Rojviroon, Tae Hwan Oh, Paramasivam Shanmugam, Arumugam Priyadharsan
{"title":"Eco-Friendly CuMoO4/Bi2S3 Nanocomposites: Superior Solar-Light Catalysts for Indigo Carmine Dye Degradation and Its Antibacterial Efficacy","authors":"Ramasamy Govarthini,&nbsp;Shanmugam Vignesh,&nbsp;Elango Visithira,&nbsp;Govindasami Periyasami,&nbsp;Lalitha Gnanasekaran,&nbsp;Rajendran Ranjith,&nbsp;Thammasak Rojviroon,&nbsp;Tae Hwan Oh,&nbsp;Paramasivam Shanmugam,&nbsp;Arumugam Priyadharsan","doi":"10.1007/s10876-025-02835-w","DOIUrl":"10.1007/s10876-025-02835-w","url":null,"abstract":"<div><p>In this study, Bi<sub>2</sub>S<sub>3</sub>, CuMoO<sub>4</sub>, and a novel CuMoO<sub>4</sub>/Bi<sub>2</sub>S<sub>3</sub> nanocomposite were successfully synthesized via a straightforward solvothermal and hydrothermal method. The resulting nanocomposites underwent comprehensive characterization utilizing XRD, FTIR, XPS, TEM, and UV-vis DRS techniques to elucidate their structural, chemical, morphological, and optical properties. Furthermore, the photocatalytic performance of Bi<sub>2</sub>S<sub>3</sub>, CuMoO<sub>4</sub>, and the CuMoO<sub>4</sub>/Bi<sub>2</sub>S<sub>3</sub> nanocomposite was evaluated through the degradation of Indigo carmine dye (IC) under solar light irradiation. Remarkably, the CuMoO<sub>4</sub>/Bi<sub>2</sub>S<sub>3</sub> nanocomposite displayed significantly enhanced photocatalytic efficiency compared to individual Bi<sub>2</sub>S<sub>3</sub> and CuMoO<sub>4</sub> counterparts. The CuMoO<sub>4</sub>/Bi<sub>2</sub>S<sub>3</sub> heterojunction reduces electron–hole (e<sup>–</sup>–h<sup>+</sup>) recombination and enhances visible light absorption, significantly improving photocatalytic degradation. Under solar light, CuMoO<sub>4</sub>/Bi<sub>2</sub>S<sub>3</sub> achieves 98% degradation efficiency, surpassing Bi<sub>2</sub>S<sub>3</sub> (46%) and CuMoO<sub>4</sub> (53%). The investigation into photodegradation kinetics revealed adherence to the pseudo-first-order model, with the CuMoO<sub>4</sub>/Bi<sub>2</sub>S<sub>3</sub> nanocomposite demonstrating a larger rate constant than Bi<sub>2</sub>S<sub>3</sub> and CuMoO<sub>4</sub>, affirming its superior photocatalytic activity. Additionally, the photostability of the CuMoO<sub>4</sub>/Bi<sub>2</sub>S<sub>3</sub> nanocomposite was explored, and a plausible photocatalytic mechanism was proposed. The antibacterial activity was tested against <i>Staphylococcus aureus</i> (<i>S.aureus</i>) and <i>Escherichia coli</i> (<i>E.coli</i>). The findings suggest promising ways for employing these composite materials in various environmental remediation and energy conversion applications.</p></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"36 3","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144073639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mitochondria-Targeted Nanoparticles and their Progress in the Treatment of Cerebral Ischaemia-Reperfusion Injury 线粒体靶向纳米颗粒治疗脑缺血再灌注损伤的研究进展
IF 2.7 4区 化学
Journal of Cluster Science Pub Date : 2025-05-17 DOI: 10.1007/s10876-025-02832-z
Jun Li, Sen Tong, Yi Hou, Ronghui Liu, Wenchao Hu, Song Tao, Hong Huang, Junzi Wu
{"title":"Mitochondria-Targeted Nanoparticles and their Progress in the Treatment of Cerebral Ischaemia-Reperfusion Injury","authors":"Jun Li,&nbsp;Sen Tong,&nbsp;Yi Hou,&nbsp;Ronghui Liu,&nbsp;Wenchao Hu,&nbsp;Song Tao,&nbsp;Hong Huang,&nbsp;Junzi Wu","doi":"10.1007/s10876-025-02832-z","DOIUrl":"10.1007/s10876-025-02832-z","url":null,"abstract":"<p>Therapeutic strategies targeting mitochondria, which is at the centre of cellular energy metabolism and a significant source of reactive oxygen species, have become a particular focus in research. Advances in nanomedicine have provided new approaches for mitochondria-targeted therapies, mainly including lipophilic cations and mitochondria-targeted peptides. However, in cerebral ischaemia–reperfusion injury (CIRI), targeted treatment is more complex due to the presence of the blood–brain barrier. This topic has emerged as a critical area of research. This review introduces the common strategies of mitochondrial targeting, focuses on the targeting role and overall efficacy of mitochondria-targeted nanoparticles in CIRI models and finally analyses the advantages and potential shortcomings of this therapeutic strategy in CIRI. This article provides a valuable theoretical basis and useful research ideas for the further development and optimisation of mitochondria-targeted nanotherapeutic strategies for CIRI.</p>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"36 3","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144073637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retraction Note: Single-Step Biofabrication of Silver Nanocrystals UsingNaregamia Alata: A Cost Effective and Eco-Friendly Control Tool in the Fight against Malaria, Zika Virus and St. Louis Encephalitis Mosquito Vectors 撤稿说明:利用纳雷伽米亚单步生物制造银纳米晶体:一种成本效益高、环保的控制工具,用于对抗疟疾、寨卡病毒和圣路易斯脑炎蚊子载体
IF 2.7 4区 化学
Journal of Cluster Science Pub Date : 2025-05-14 DOI: 10.1007/s10876-025-02844-9
Raja Mohamed Sait Thameem Azarudeen, Marimuthu Govindarajan, Abubucker Amsath, Udaiyan Muthukumaran, Giovanni Benelli
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