Journal of Cluster Science最新文献

{"title":"Effects of Hexagonal Boron Nitride and Mesoporous Silica Nanoparticles on the Morphology, Mechanical Properties and Antimicrobial Activity of Dental Composites","authors":"Sedef Kaptan Usul,&nbsp;Ayşe Aslan,&nbsp;Hatice Büşra Lüleci,&nbsp;Bengü Ergüden","doi":"10.1007/s10876-024-02658-1","DOIUrl":"10.1007/s10876-024-02658-1","url":null,"abstract":"<div><p>Hexagonal boron nitride (HBN), an artificial material with unique properties, is used in many industries. This article focuses on the extent to which hexagonal boron nitride and silica nanoparticles (MSN) affect the physicochemical and mechanical properties and antimicrobial activity of prepared dental composites. In this study, HBN, and MSN were used as additives in dental composites. 5% and 10% by weight of HBN are added to the structure of the composite materials. FTIR analysis were performed to determine the components of the produced boron nitride powders, hexagonal boron nitride-containing composites, and filling material applications. The structural and microstructural properties of dental composites have been extensively characterized using X-ray diffractometry (XRD). Surface morphology and distributions of nano boron nitride were determined by scanning electron microscopy (SEM)-EDS. In addition, the solubility of dental composites in water and their stability in water and chemical solution (Fenton) were determined by three repetitive experiments. Finally, the antimicrobial activity of dental composites was detected by using Minimum Inhibitory Concentration (MIC) measurement, as well as Minimum Fungicidal Concentration (MFC) method against yeast strain <i>Saccharomyces cerevisiae</i>, and Minimum Bactericidal Concentration (MBC) method against bacteria strains, <i>Staphylococcus aureus</i> and <i>Escherichia coli</i>. Since the HMP series have better antimicrobial activity than the HP series, they are more suitable for preventing dental caries and for long-term use of dental composites. In addition, when HMP and HP series added to the composite are compared, HMP-containing dental composites have better physicochemical and mechanical properties and therefore have a high potential for commercialization.</p></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"35 7","pages":"2293 - 2309"},"PeriodicalIF":2.7,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s10876-024-02658-1.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141640853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of Bimetallic Copper oxide-silver Nanoparticles by Gum Arabic: Unveiling Antimicrobial, and Antibiofilm Potential against some Pathogenic Microbes Causing Wound Infection","authors":"Roqayah Saleh Al-Habeeb,&nbsp;Widad M. Al-Bishri","doi":"10.1007/s10876-024-02656-3","DOIUrl":"10.1007/s10876-024-02656-3","url":null,"abstract":"<div><p>The adoption of environmentally friendly approaches in NPs production represents a pivotal stride towards achieving sustainability in nanotechnology through biomass conversion. Due to their potential for synergy at low concentrations and biological applications, bimetallic nanoparticles have drawn a lot of attention recently. In the current work, Gum Arabic as a biological macromolecules source was used to create bimetallic copper oxide-silver nanoparticles (CuO-Ag NPs) in an economical and environmentally friendly manner. Bimetallic CuO-Ag NPs were successfully synthesized at the nanoscale, showed excellent dispersion, and formed stable colloidal nano-solutions, according to their characterization. Additionally, the antifungal and antibacterial potentials of bimetallic CuO-Ag NPs were assessed in relation to some pathogenic microbes that were isolated from the sides of wounds. Also, growth curve assay had been performed to <i>P. aeruginosa</i>, and <i>S. epidermidis</i> after the treatment by bimetallic CuO-Ag NPs. Finally, antibacterial reaction mechanism had been determined by SEM imaging process. Bimetallic CuO-Ag NPs’ minimum inhibitory concentration (MIC) was determined for every tested strain of yeast and bacteria. With inhibition zones of 22 ± 1.80 mm, and 26 ± 1.0 mm (at a concentration of 50 µg/mL), the results showed the antibacterial activity of bimetallic CuO-Ag NPs against <i>P. aeruginosa</i>, and <i>S. epidermis</i>, respectively. In summary, Gum Arabic was effectively used to create bimetallic CuO-ZnO NPs, which demonstrated promising antimicrobial properties, paving the path for their safe implementation in a variety of biomedical applications specially to treat some pathogenic microbes-causing wound infection.</p></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"35 7","pages":"2311 - 2327"},"PeriodicalIF":2.7,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141642069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemical Modification of Cu2O Nanoparticles with Triacetoxy(Vinyl)Silane: Enhanced Dispersion, Abrasion Resistance, and Thermal Stability in Acrylic Coatings","authors":"Xuan Thang Dam,&nbsp;Thuy Chinh Nguyen,&nbsp;Anh Hiep Nguyen,&nbsp;Dinh Hieu Vu,&nbsp;Thi Ngoc Lien Ly,&nbsp;Hoang Nghia Trinh,&nbsp;Thi Lan Phung,&nbsp;Tuan Anh Nguyen,&nbsp;Phi Hung Dao,&nbsp;Hoang Thai","doi":"10.1007/s10876-024-02659-0","DOIUrl":"10.1007/s10876-024-02659-0","url":null,"abstract":"<div><p>The synthesis of Cu₂O nanoparticles (NPs) through the reduction of copper hydroxide using ascorbic acid and then Cu₂O NPs modified with triacetoxy(vinyl)silane (TVAS) (m-Cu₂O) by solution method were achieved. FTIR analysis of the unmodified Cu₂O NPs and m-Cu₂O NPs revealed the presence of absorption characteristics corresponding to Cu–O–Si linkages in the FTIR spectra of m-Cu₂O NPs, which is strong evidence that the Cu₂O NPs have been successfully modified. The characteristics and properties of m-Cu₂O NPs were determined and compared to those of the u-Cu₂O NPs. The results indicated that the modification process had an insignificant effect on the crystal structure and morphology of Cu₂O NPs. X-ray diffraction analysis indicated that the crystal grain size of m-Cu₂O NPs slightly increased, measuring 41.04 nm compared to 38.36 nm for the u-Cu₂O NPs, this change was minor. However, the m-Cu₂O NPs demonstrated enhanced dispersion into acrylic emulsion polymer, resulting in improved abrasion resistance and thermal stability of the acrylic coating. In comparison with an acrylic coating filled with the u-Cu₂O NPs, the coating filled with m-Cu₂O NPs exhibited a 70% increase in abrasion resistance and better thermal stability. Importantly, the antibacterial performance against <i>E. coli</i> and <i>S. aureus</i> of acrylic coating filled with m-Cu₂O NPs was similar to that of the u-Cu₂O NPs nanocomposite coating. These findings underscore the versatility and benefits of chemical modification in enhancing specific properties of the acrylic coating without compromising antibacterial efficacy.</p></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"35 7","pages":"2329 - 2340"},"PeriodicalIF":2.7,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141641932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BSA-Incorporated Sulphur and Nitrogen Doped Carbon dots (BSA-S,N-CDs) Based Platform for turn-on Fluorescence Detection of Histidine in Presence of Cu2+ ion","authors":"Aswathy A. O,&nbsp;Sony George","doi":"10.1007/s10876-024-02661-6","DOIUrl":"10.1007/s10876-024-02661-6","url":null,"abstract":"<div><p>Measuring of histidine levels can be used as an indication of the onset of diseases such as chronic kidney disease (CKD), anaemia, and cancer, etc. Due to its abnormal level in human diseases, histidine (His) monitoring has received a lot of interest. Here a feasible, sulphur and nitrogen-doped carbon dots-based (BSA-S,N-CDs) fluorescent switch-off-on nano sensor has been developed for the detection of histidine in an aqueous solution. The BSA-S,N-CDs was synthesized <i>via</i> microwave-assisted method from citric acid, urea, and bovine serum albumin (BSA). The blue fluorescence of BSA-S,N-CDs ( λ_em: 444 nm) was quenched in the presence of Cu²⁺ ion by static quenching and the quenched probe (BSA-S,N-CDs@Cu²⁺ ) was used for the detection of histidine in the linear range from 0.29 to 2.33 mM. The limit of detection (LOD) and quantification (LOQ) of the probe was obtained as 34.55 µM and 115.18 µM respectively. The sensor exhibits good selectivity and less interference toward various biomolecules and ions. The BSA-S,N-CDs@Cu²⁺ probe was used to detect histidine in spiked human serum and urine samples. Additionally, a paper strip-based sensor was developed to validate its practical applicability.</p></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"35 7","pages":"2341 - 2352"},"PeriodicalIF":2.7,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141643744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Ruthenium Metal Complexes and Their Applications as a Light-Absorbing Material/ A DFT Study","authors":"Faeq A. AL-Temimei","doi":"10.1007/s10876-024-02657-2","DOIUrl":"10.1007/s10876-024-02657-2","url":null,"abstract":"<div><p>We have developed new derivatives of Ruthenium metal complex-based dyes for use as sensitizers in DSSCs. Theoretical investigations have been conducted on ten Ruthenium metal complex clusters to analyse their geometries, electronic structures, density of states, optical properties, photovoltaic properties, and electrochemical properties. These investigations were carried out using the Density Functional Theory (DFT) and Time-Dependent Density Functional Theory (TD-DFT) methods. The objective was to design novel ligands that enhance the performance of dyes in dye-sensitized solar cells. We evaluated the impact of various chalcogen atoms in the ligand donor moieties, using different aromatic annulenes as building blocks. Additionally, we examined the influence of different functional groups connected to the bipyridyl unit in the ligand acceptor moiety. The designed dyes exhibit red-shifted spectra and improved electron transition abilities compared to other dyes, resulting in more effective intramolecular charge transfer upon photo-excitation. This suggests that these dyes would deliver the best photovoltaic performance. Furthermore, the designed dyes demonstrate a significantly enhanced light-harvesting efficiency, a higher open-circuit voltage (<span>({text{V}}_{text{o}text{c}})</span>), a greater short-circuit current, and favourable electrochemical properties. These characteristics are crucial for achieving faster electron injection efficiency and higher performance in photovoltaic devices.</p></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"35 7","pages":"2283 - 2291"},"PeriodicalIF":2.7,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141647683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highly Sensitive and Selective Gas Sensors for Ethanol Based on Mn Doped ZnO Nanoflakes","authors":"Mangesh Awale,&nbsp;S. D. Lokhande,&nbsp;L. H. Kathwate,&nbsp;M. Vasundhara,&nbsp;V. D. Mote,&nbsp;A. B. Kadam","doi":"10.1007/s10876-024-02662-5","DOIUrl":"10.1007/s10876-024-02662-5","url":null,"abstract":"<div><p>Low-operating temperature gas sensors play a pivotal role in environmental and health safety. Here, we investigate the performance of hexagonal ZnO nanostructures for detecting hazardous ethanol gas. Pure and 3% Mn doped ZnO thin films were synthesized by a spray pyrolysis method. The study focused on investigating structural, morphological, chemical composition, optical and gas sensing properties of these films. By adding 3% Mn doping, the structural, morphological and optical properties of ZnO film notably changed. The 3% Mn-doped ZnO thin film exhibits a high response of 360 compared to undoped ZnO (154) towards 50 ppm of ethanol at room temperature. This may be due to the increased surface reactivity and defects sites. The response/recovery time of the Mn-doped ZnO to ethanol is found to be 18/40s. Gas sensing studies suggest that the 3% Mn-doped ZnO thin film has good reproducibility, stability and selectivity. The sensing mechanism of ethanol by Mn-doped ZnO thin films is studied and discussed. These findings suggest that Mn-doped ZnO thin films are promising candidates for low temperature ethanol sensing application.</p></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"35 7","pages":"2273 - 2282"},"PeriodicalIF":2.7,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141646245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Curcumin Nanoemulgel: Characterization, Optimization, and Evaluation of Photoprotective Efficacy, Anti-Inflammatory Properties, and Antibacterial Activity","authors":"Amir Mohammad Bagheri,&nbsp;Mehdi Ranjbar,&nbsp;Somayyeh Karami-Mohajeri,&nbsp;Mohammad Hassan Moshafi,&nbsp;Yasmin Dehghan Noudeh,&nbsp;Mandana Ohadi,&nbsp;Gholamreza Dehghannoudeh","doi":"10.1007/s10876-024-02651-8","DOIUrl":"10.1007/s10876-024-02651-8","url":null,"abstract":"<div><p>As a natural bioactive compound, curcumin (Cur) has traditionally used for various therapeutic purposes, but due to low solubility, poor skin permeability, and the possibility of superficial staining, its topical applications is restricted. Thus, this study aimed to develop a topical formulation, increasing the solubility of Cur and promoting potential applications. In this context, Cur nanoemulsions were prepared through continuous emulsification and optimized with different ratios of components to achieve desirable properties and superior encapsulation. Accordingly, nanoemulsions prepared by the oleic acid (10%w/w) as oil phase, PEG 400 (6%w/w) as co-surfactant and mixture of Tween 80® and Span 80® (8%w/w) as surfactant showed the most favorable properties with a droplet size of 12.26 nm and polydispersity index (PDI) of 0.254. Afterward, the optimized formulation was converted to nanoemulgel using 1%w/w of Carbopol 940. The Cur formulation presented good physiochemical properties in terms of uniformity, thermodynamic stability, spreadability, and droplet size. The results showed that the release profile follows the Higuchi kinetic model. Moreover, this formulation presented excellent antioxidant capacity (FRAP value of 533.49 ± 2.84 µM Fe (II)/g) and potential photoprotective efficacy (SPF value of 13.86). It was also found to have high anti-inflammatory properties and antibacterial activity (250 µg/ml ≤ MIC &lt; 500 µg/ml) against <i>Staphylococcus aureus</i> and <i>Escherichia coli</i>. According to the results, the current formulation of Cur is a promising candidate to improve the solubility and promote its efficacy for various topical applications.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"35 7","pages":"2253 - 2272"},"PeriodicalIF":2.7,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141614210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A 6-Connected {Cu2O5} Cluster-Based Metal-Organic Framework Based on Tetrabromoterephthalate: Synthesis, Crystal Structure and Fluorescent Properties","authors":"Yan-Fei Wang,&nbsp;Hang-Yi An,&nbsp;Qian Mao,&nbsp;Lin-Tao He,&nbsp;Shu-Yan Li,&nbsp;Jia-Ming Li","doi":"10.1007/s10876-024-02655-4","DOIUrl":"10.1007/s10876-024-02655-4","url":null,"abstract":"<div><p>An interseting Cu(II)-based organic framework containing a Cu₂O₅ cluster, [Cu (TBA)(CH₃OH)]_<i>n</i> (<b>1</b>) has been hydrothermally synthesized with tetrabromoterephthalate (H₂TBA) ligand, and characterized through infrared spectroscopy (IR), elemental and thermal analysis (EA), power X-ray diffraction (PXRD), and single-crystal X-ray diffraction (SCXRD) analyses. The X-ray single-crystal diffraction analysis shows that the Cu^II center is hexa-coordinated and situated on perfect octahedral geometry formed by four carboxyl oxygen atoms of four symmetry-related TBA²⁻ anions and two O-donors of two reverse <i>µ</i>₂-CH₃OH bridges. Each TBA²⁻ ligand plays as a <i>µ</i>₄ tetra-monodentate linker and connect four Cu²⁺ cations together to form the three dimensional structure of <b>1</b>. Surprisingly, there are no significant hydrogen bonds and <i>π</i>-stack interactions in <b>1</b>, but the Br<b>···</b>Br halogen bonds interactions. Detailed topology analysis found that the 3D cluster-based metal-organic framework of <b>1</b> can be simplified to 4 topological types: a 4-c 1-nodal net <i>dia</i> with point symbol {6⁶}, a 6,6-c 2-nodal net <i>htp</i> with point symbol {4¹³·6²}{4⁸·6⁶·8}, a 4,6-c 2-nodal net <i>bpq</i> with point symbol {3²·6²·7²}{3⁴·4²·6⁴·7⁵}, and a 6,8-c 2-nodal net <i>6,8T902</i> with point symbol {3⁴·4⁴·5⁴·6³}{3⁸·4¹⁴·5⁴·6²}, respectively. Moreover, <b>1</b> exhibits intense solid-state luminescence emissions centered at 478 nm at room temperature, which mainly originates from the intraligand π→ π* transitions of TBA²⁻. The CCDC number of <b>1</b> is 2,355,788.</p></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"35 7","pages":"2591 - 2599"},"PeriodicalIF":2.7,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141574156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Heat Treatment and Electrolyte Type on the Properties of Vanadium Pentoxide","authors":"M. Fuentes-Pérez,&nbsp;J. Castrellón-Uribe,&nbsp;U. León-Silva,&nbsp;D. Hernández-Martínez,&nbsp;S. García-Carvajal,&nbsp;M. E. Nicho","doi":"10.1007/s10876-024-02653-6","DOIUrl":"10.1007/s10876-024-02653-6","url":null,"abstract":"<div><p>In this work, the effect of heat treatment in the synthesis of vanadium pentoxide (V₂O₅) on its physicochemical properties was studied. Furthermore, the effect of liquid and viscous electrolytes based on lithium perchlorate (LiClO₄) on the performance of electrochromic devices (ECDs) was evaluated using heat-treated V₂O₅ as electrochromic film. V₂O₅ was synthesized using the chemical bath technique. The V₂O₅ without and with heat treatment at 400 °C was characterized using FT-IR, UV-Vis, XRD, XPS, FESEM, AFM, and cyclic voltammetry (CV) techniques. Better physicochemical behavior was shown by the thermally treated V₂O₅, which is why it was used in the ECDs. Single ECDs were characterized using optical transmittance spectra, kinetic curves, and electrochemical impedance spectroscopy. A broadening of the absorption band towards the red and better electrochemical properties were observed when a thermal treatment was applied to the amorphous V₂O₅. A charge storage capacity of 1061.42 mC/cm² was obtained for the crystalline V₂O₅ film (with heat treatment) compared to the charge storage capacity of 303.38 mC/cm² obtained for the amorphous V₂O₅ film. A better distribution and decrease in grain size was observed for V₂O₅ with heat treatment. The CV curves showed higher stability of crystalline V₂O₅ compared to amorphous V₂O₅, even after several cycles and at different scan rates. A higher flow of ions between the working electrode and the counter electrode was achieved with the use of liquid electrolyte in the ECD, allowing a more efficient ECD with greater change in transmittance in the near-infrared region, compared to the use of viscous electrolyte. This research work contributes to the improvement of the physicochemical properties of V₂O₅.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"35 7","pages":"2571 - 2589"},"PeriodicalIF":2.7,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141574163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biological Efficacy Evaluation of Lab Synthesized MgGA Bio-MOF as an Antioxidant Agent and Drug Vehicle","authors":"Manu Sharma,&nbsp;Gagandeep Kaur,&nbsp;Pawan Kumar","doi":"10.1007/s10876-024-02650-9","DOIUrl":"10.1007/s10876-024-02650-9","url":null,"abstract":"<div><p>In this work, a magnesium-based biomolecule metal organic framework (MgGA Bio-MOF) has been synthesized using magnesium chloride hexahydrate (MgCl₂.6H₂O) as a metal cation and an edible linker gallic acid (GA, C₆H₂(OH)₃CO₂H) as a organic building unit in water under certain experimental conditions. Initially, MgGA Bio-MOF synthesis has been confirmed through  spectroscopic and microscopic analysis techniques. Afterwards, 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay has been performed to know the antioxidant activity of MOF. From the DPPH assay, it has been found that MgGA Bio-MOF possesses 70.4% scavenging activity. To proceed further, the drug release studies have been performed through IBU@MgGA Bio-MOF conjugate using UV- vis spectroscopy In investigation of drug release studies, we have observed 79% IBU released up to 150 min from IBU@MgGA Bio-MOF conjugate at neutral pH. After that, a constant absorbance has been observed, indicating the complete release of IBU. Overall, we found the selected BioMOF has excellent biological utility as an antioxidant agent as well as an anti-inflammatory drug carrier in line of its real-world applications</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"35 7","pages":"2243 - 2251"},"PeriodicalIF":2.7,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141550438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}