Journal of Cluster Science最新文献

{"title":"Synthesis, Structure and Fluxional Behaviour of Sulfido-Capped Triruthenium Clusters Containing a Bridging 1,1’-Bis(diphenylphosphino)ferrocene Ligand","authors":"Profulla Mondol,&nbsp;Md. Abdullah Al Mamun,&nbsp;Md. Emdad Hossain,&nbsp;Shishir Ghosh,&nbsp;Vladimir N. Nesterov,&nbsp;Shariff E. Kabir","doi":"10.1007/s10876-024-02648-3","DOIUrl":"10.1007/s10876-024-02648-3","url":null,"abstract":"<div><p>The reactivity of dppf-bridged triruthenium [Ru₃(CO)₁₀(µ-dppf)] with three thiourea derivatives namely <i>N,N´</i>-diisopropylthiourea, <i>N,N´</i>-dimethylthiourea and tetramethylthiourea has been examined. The reaction of [Ru₃(CO)₁₀(µ-dppf)] with <i>N,N´</i>-diisopropylthiourea or <i>N,N´</i>-dimethylthiourea affords [Ru₃(CO)₆{κ¹-SC(NHR)₂}(µ-dppf)(µ₃-S)₂] (<b>1</b>, R = CHMe₂; <b>2</b>, R = Me) that contains an intact thiourea ligand coordinated to a single ruthenium atom using the sulfur atom. The previously reported [Ru₃(CO)₇(µ-dppf)(µ₃-S)₂] (<b>3</b>) is also isolated as the minor product from the reaction with <i>N, N´</i>-dimethylthiourea. Both <b>1</b> and <b>2</b> furnishes <b>3</b> upon thermolysis in boiling toluene as confirmed by control experiments. In contrast, similar reaction between [Ru₃(CO)₁₀(µ-dppf)] and tetramethylthiourea furnishes [Ru₃(CO)₅(µ-CO){µ-η¹,κ¹-COPh}(µ-PhPFcPPh₂)(µ₃-S)] (<b>4</b>) and [HRu₃(CO)₇(µ-OH)(µ-dppf)(µ₃-S)] (<b>5</b>) together with small amount of <b>3</b>. All the new clusters are fluxional in solution which has been probed by VT NMR experiments and their molecular structures have been established by single-crystal X-ray diffraction analysis.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div><div><p>The reactions of dppf-bridged triruthenium cluster [Ru₃(CO)₁₀(µ-dppf)] with some thiourea derivatives have been investigated which leads to the isolation and characterization of four new triruthenium clusters</p></div></div></figure></div></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"35 8","pages":"2705 - 2719"},"PeriodicalIF":2.7,"publicationDate":"2024-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141367687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two Metallic Nanoparticles Formulas of Phyllostachys heterocycla Extract Exhibited Potent Cytotoxicity against Ovarian Cancer Cells through Apoptosis Induction","authors":"Reda F. A. Abdelhameed,&nbsp;Mohamed S. Nafie,&nbsp;Ahmed K. Ibrahim,&nbsp;Amany K. Ibrahim,&nbsp;Maged S. Abdel-Kader,&nbsp;Safwat A. Ahmed,&nbsp;Gharieb S. El-Sayyad,&nbsp;Ahmed I. El-Batal,&nbsp;Koji Yamada,&nbsp;Jihan M. Badr,&nbsp;Eman S. Habib","doi":"10.1007/s10876-024-02645-6","DOIUrl":"10.1007/s10876-024-02645-6","url":null,"abstract":"<div><p><i>Phyllostachys heterocycla</i> is well-known for its high diversity of bioactive metabolites, which are the reason for its various potential medical uses for which anticancer activity has been proven. Herein, <i>Phyllostachys heterocycla</i> extract was prepared in two different metallic nanoparticle formulas such as iron oxide nanoparticle-boron, and iron oxide nanoparticle-humic acid (Fe₂O₃ NP-B and Fe₂O₃ NP-HA) with average particle sizes of 12.25 nm and 15.80 nm, respectively. <i>Phyllostachys heterocycla</i> extract and the two nano-formulas were investigated to obtain their cytotoxic activity. The crude extract exhibited potent cytotoxic activity against the ovarian (OVCAR-3) cancer cell line, with IC₅₀ values of 16.3 µg/mL. In comparison, the two nano-loaded forms displayed a much more promising cytotoxic activity with IC₅₀ values of 0.9 µg/mL for Fe₂O₃ NP-HA, and 6.4 µg/mL for Fe₂O₃ NP-B. Additionally, NP-HA and NP-B showed potent cytotoxic activities against prostate (PC-3) and pancreatic (Panc1) cancer cell lines with IC₅₀ values of 2.31, 6.3 µg/mL for Fe₂O₃ NP-HA, and 14.9, 16.8 µg/mL for Fe₂O₃ NP-B. For apoptosis investigation, Fe₂O₃ NP-HA induced total ovarian apoptotic cell death by a 87.34-fold change, and necrosis by 1.29-fold change. Regarding cell cycle analysis, Fe₂O₃ NP-HA-PHE arrested the cell proliferation of OVCAR-3 cells in S-phase, with an increased cell population at S-phase of 42.6%. Additionally, it confirmed the apoptosis mechanism by inhibiting the antiapoptotic gene and activating the proapoptotic gene markers. Moreover, upon continuation of our phytochemical investigation of the plant, additional chemical components of the crude extract of <i>Phyllostachys heterocycla</i> were isolated using various chromatographic techniques. As a result, six compounds were isolated. By using different spectroscopic data, the chemical structures of the pure isolated compounds were assigned as stigmasterol (1), glyceryl monobehenate (2), vanillic acid (3), ferulic acid (4), catechin (5), and thymidine (6). These isolated compounds were previously reported for their potent cytotoxic activities against panel of cancer cell lines including pancreatic cancer and prostate cancer cell lines (Ferulic acid), beside the anti-tumor potential against ovarian cell lines (Stigmasterol). In addition to the cytotoxic activity against human larynx carcinoma HepG-2 cell lines (Catechin), human breast cancer MCF7 (Thymidine), and human colon cancer cell line HT-29 (Vanillic acid). Which may explain the significant cytotoxic and anticancer properities of the crude extract of <i>Phyllostachys</i> <i>heterocycla</i>.</p></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"35 7","pages":"2557 - 2569"},"PeriodicalIF":2.7,"publicationDate":"2024-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s10876-024-02645-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141368344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fabrication of Nanostructured Surfaces Towards the Prevention of Hospital-Acquired Infection","authors":"Sanjeev Kumar Paikra,&nbsp;Samir Bauri,&nbsp;Monalisa Mishra","doi":"10.1007/s10876-024-02652-7","DOIUrl":"10.1007/s10876-024-02652-7","url":null,"abstract":"<div><p>\u0000 Hospital-acquired infections are a marked burden on the healthcare system and the leading cause of death in hospitals. Medical devices and implants contribute significantly to the infection because it has direct contact with the patient body cavity. To solve this issue surface of the devices needs to be modified for efficient functioning. To achieve different surface properties advanced surface modification strategies like plasma-assisted surface modification, plasmonic lithography, nanopatterning by laser beam or electron beam, and chemical etching oxidation can be used. Nanostructure inhibits bacterial growth without causing toxicity or the least toxicity to the surrounding tissue in the human body. The current review summarizes the numerous surface modification strategies adopted for developing novel nanostructured surfaces with more emphasis on titanium-based nanostructure in medical devices along with a brief review of the bactericidal mechanism. This review also sheds some light on the biomedical importance of polymeric and Inorganic nanocomposite materials with their biocompatibility and toxicity profile.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"35 6","pages":"1687 - 1707"},"PeriodicalIF":2.7,"publicationDate":"2024-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141366679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Glutathione Capping on Copper Nanoclusters and Nanoparticles: A Review","authors":"Mamta Sahu,&nbsp;Mainak Ganguly,&nbsp;Ankita Doi","doi":"10.1007/s10876-024-02639-4","DOIUrl":"10.1007/s10876-024-02639-4","url":null,"abstract":"<div><p>Being a highly available 3d group11 transition metal, copper in the form of nanoparticles (NPs) and nanoclusters (NCs) has been extensively investigated. However, aerial oxidation limits its application. Capping agents and experimental conditions have quite a significance in the stability of copper particles. Here, we reviewed the glutathione (GSH) capping on copper nanopaticles (CuNPs) and copper nanoclusters (CuNCs). CuNCs and CuNPs benefit greatly from the stabilizing, modifying, and enhancing effects of GSH, a naturally occurring tripeptide. It assists in preventing their aggregation, which is a typical problem for these tiny particles. Strong metal-sulfur (Cu-S) interactions allow the thiol (-SH) groups in GSH molecules to attach to the copper surface, forming a protective coating that prevents copper particles from clumping together. The synthesis with the mechanism, and the fate of copper particles, with myriad applications such as bioimaging, antibacterial activity, and sensing (antibiotics, heavy metals, pH, and other biomolecules) were reviewed here. Such particles were satisfactorily biocompatible. Moreover, the effect of components was also summarized justifying that tripeptide GSH was much superior to individual components in the context of applications, although cysteine was considered to be a pivotal component. The effect of adulteration of other metals in copper particles often enhances their utility. This review will open a new window for thiolated capping to young researchers, venturing into the field of material science.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"35 6","pages":"1667 - 1685"},"PeriodicalIF":2.7,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141257109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fabrication of β-Cyclodextrin-Assisted Tungsten Trioxide Nanosheets and Their Remarkable Adsorption, Photocatalytic Performance, and Biomedical Properties","authors":"Tahani Y. A. Alanazi,&nbsp;Arwa A. Makki,&nbsp;Dina Hajjar,&nbsp;Jawza Sh Alnawmasi,&nbsp;Nawaa Ali H. Alshammari,&nbsp;Alya M. Alotaibi,&nbsp;Fahad M. Almutairi","doi":"10.1007/s10876-024-02647-4","DOIUrl":"10.1007/s10876-024-02647-4","url":null,"abstract":"<div><p>Regulating a material’s crystal phase is difficult when using a solution-based method; however, this has far-reaching implications for the characteristics of the material. The current work reported herein represents an efficient realization of green synthesized adjustable layered tungsten oxide (WO₃) nanosheets using β-Cyclodextrin (β-CD) biopolymer. Both nucleation process and sheet formation were greatly influenced by chelating ability of β-CD. These qualities allowed bonding between WO₃ nanosheet and β-CD to occur after calcination at 450 °C yielding β-CD-assisted tungsten oxide nanosheets (WO₃). Various analytical methods such as XRD, SEM, TEM, EDX, FTIR and UV–Vis spectrophotometry were employed to understand physicochemical properties of the prepared WO₃ nanosheets. The main aim of this study was to investigate visible light-assisted photocatalytic degradation of Methylene Blue (MB). According to experimental results, within 24 min 98.8% decomposition efficiency towards MB was recorded under irradiation using visible light source in presence of 200 mg WO₃ nanosheet catalysts. The experiment was conducted in two sets that is with and without addition of WO₃ nanosheet catalysts respectively. Furthermore evaluation on antibacterial activity against <i>Escherichia coli</i> (<i>E.coli</i>), and <i>Staphylococcus aureus</i> (<i>S.aureus</i>) bacteria as well antioxidant power was performed for these nano sheets while anticancer and antioxidant effects were also evaluated which demonstrated all samples having significant antibacterial activities together with antioxidants performances in terms of WO₃ nanosheets against different bacteria strains including <i>E. coli</i>, <i>S. aureus</i>. Moreover, it showed strong anticancer potentials coupled with their excellent free radical scavenging abilities thus making them perfect candidates for use as potential therapeutic agents.</p></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"35 6","pages":"2133 - 2147"},"PeriodicalIF":2.7,"publicationDate":"2024-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141254869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anticancer and Photocatalytic Activity of Ag-doped TiO2 Nanoparticles Synthesized Using Carica papaya Leaf Extract","authors":"Farjana Khadar A,&nbsp;Arun Kumar Mani","doi":"10.1007/s10876-024-02640-x","DOIUrl":"10.1007/s10876-024-02640-x","url":null,"abstract":"<div><p>In this study, the Ag-incorporated TiO₂ nanoparticles were synthesized using <i>Carica papaya</i> leaf extract, intending to evaluate their potential efficacy against the MCF-7 breast cancer cell line. The physio-chemical features of the biogenic-produced Ag-TiO₂ nanoparticles are investigated using several analytical techniques, including UV-Vis spectroscopy, X-ray Diffraction (XRD), Fourier-transform Infrared Spectroscopy (FTIR), Transmission Electron Microscopy (TEM), Selected Area Electron Diffraction (SAED), Field Emission Scanning Electron Microscopy (FE-SEM), Energy-dispersive X-ray Spectroscopy (EDAX), Zeta potential analysis, and Particle size analysis. The Ag-TiO₂ nanoparticles exhibit a spherical morphology and possess an average diameter of 8-12 nm. Additionally, their surface is characterized by a negative charge, which contributes to their rough texture. The results of the <i>in-vitro</i> anticancer experiments demonstrated that the Ag-TiO₂ nanoparticles (NPs) induce vacuolization in cancer cells, alter the shape of the cell nucleus, degrade nucleic acids, and arrest the synthetic phase of cancer cells in the cell cycle. The degradation capacity of pure and Ag-TiO₂ NPs was also assessed in relation to the degradation of Methylene Blue (MB) dye when exposed to solar irradiation. The results indicated that 3% Ag-TiO₂ shows 63% of dye decolorization within a time frame of 3 hours. Therefore, the synthesized Ag-TiO₂ NPs could reduce toxicity, be eco-friendly and have exceptional utility in two distinct domains that significantly have a major impact on the environment.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"35 6","pages":"2117 - 2131"},"PeriodicalIF":2.7,"publicationDate":"2024-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141254545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of Green Fluorescence CsPbBr3 Perovskite Quantum Dots Via Probe Sonication for the Detection of Isoprothiolane Fungicide in Food Samples","authors":"Mayurkumar Revabhai Patel,&nbsp;Tae Jung Park,&nbsp;Suresh Kumar Kailasa","doi":"10.1007/s10876-024-02649-2","DOIUrl":"10.1007/s10876-024-02649-2","url":null,"abstract":"<div><p>Isoprothiolane is a common pesticide used to manage a variety of crop diseases. It has also been linked to carcinogenic consequences in people when exposed to certain quantities for longer spans of time. As a result, the establishment of extremely sensitive and selective method to detect isoprothiolane is crucial for ecosystem protection and food safety. Recently, perovskite quantum dots (PQDs) have received rising interest as a result of their inherent fluorescence properties and applications in variety of domains. In the current study, we successfully synthesized cesium lead bromide (CsPbBr₃) PQDs by using modified ligand-assisted re-precipitation method via tip sonication treatment. A strong green fluorescence of CsPbBr₃ PQDs is effectively quenched after forming complex with isoprothiolane through a static quenching effect. The optical properties, morphology, chemical compositions, and diffraction patterns of CsPbBr₃ PQDs were distinguished by using fluorescence, absorption, X-ray diffraction pattern, X-ray photoelectron microscopy, and high-resolution transmission electron microscopy techniques. Under the optimal reaction conditions, CsPbBr₃ PQDs exhibit wide detection range (0.025-25 μM) and low detection limit (10.12 nM) for isoprothiolane detection. Furthermore, the nanoprobe has excellent selectivity for isoprothiolane, and it can be successfully applied to detect isoprothiolane in real samples.</p></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"35 6","pages":"2105 - 2116"},"PeriodicalIF":2.7,"publicationDate":"2024-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141254698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic Performance of ZnO/SnO2 Nanocomposites: Synthesis, Characterization, and Applications in Photocatalysis and Superoxide Radical Scavenger","authors":"Abdelmadjid Guerram,&nbsp;Salah Eddine Laouini,&nbsp;Hamdi Ali Mohammed,&nbsp;Gamil Gamal Hasan,&nbsp;Mohammed Laid Tedjani,&nbsp;Fahad Alharthi,&nbsp;Farid Menaa","doi":"10.1007/s10876-024-02642-9","DOIUrl":"10.1007/s10876-024-02642-9","url":null,"abstract":"<div><p>This study investigates the synthesis, characterization, and application of ZnO/SnO₂ nanocomposite (ZnO/SnO₂ NC), focusing on their photocatalytic and antioxidant properties. The sol-gel technique was utilized for the synthesis of the ZnO/SnO₂ NC. Subsequent characterization was performed using X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier transform infrared (FTIR) spectroscopy, and UV-visible (UV-Vis) spectrophotometry. The XRD analysis indicated crystallite dimensions of 15 nm for ZnO/SnO₂ and 21 nm for pure ZnO NPs. The photocatalytic efficiency was assessed by the degradation of Toluidine Blue (TB) and m-Toluidine Blue (m-TB) dyes. The ZnO/SnO₂ NC demonstrated degradation rates of 99% for both TB and m-TB within 120 and 140 min of sunlight exposure, respectively. Furthermore, the scavenging activity of superoxide radicals was evaluated, with the ZnO/SnO₂ NC exhibiting an Half-maximal inhibitory concentration (IC50) value of 48.12 µg∙mL^− 1, compared to 60.03 µg∙mL^− 1 for pure ZnO. This research highlights the potential of ZnO/SnO₂ NC in environmental remediation and biomedical applications.</p></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"35 7","pages":"2231 - 2242"},"PeriodicalIF":2.7,"publicationDate":"2024-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141254700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sustainable Synthesis of CuO Nanoparticles for Colorimetric Detection of Hydrogen Peroxide and Glucose","authors":"Pallavi Aggarwal,&nbsp;Jashpal Singh Rana,&nbsp;Mansi Chitkara,&nbsp;Aashish Kumar","doi":"10.1007/s10876-024-02646-5","DOIUrl":"10.1007/s10876-024-02646-5","url":null,"abstract":"<div><p>The current study demonstrates an easy utilization of glycine soja sensu auct green extract as a power source for the desired synthesis of copper oxide (CuO) nanoparticles via green synthesis process to acquire significant detection of hydrogen peroxide (H₂O₂) and monosaccharide glucose through an uncomplicated colorimetric method. Due to sustainability issues, synthesis of the metal or metal oxide nanoparticles has shifted towards eco-safe reducing agents. This research focuses on the utilization of the reducing agent via green technology, namely <i>glycine soja sensu auct</i> extract, for the synthesis of CuO nanoparticles by co-precipitation synthesis. Through XRD studies, it can be depicted that the material is monoclinic. FESEM and HRTEM images reveals spherical shape of nanoparticles. HRTEM images also indicate that the size of the particles falls between 10–30 nm. The particle distribution curve reveals the z-average size of 135.1 nm. The Fourier transform infrared spectroscopy peak at 493.14, 522.01, 557.89 and 649.39 cm^-1 refer to the vibrations between Cu and O. Clearly, the peaks indicate the formation of CuO nanostructure. These green CuO NPs successfully catalyzed the oxidation reaction of the exposed peroxidase substrate 3, 3′, 5, 5′- tetramethylbenzidine (TMB) dye by hydrogen peroxide (H₂O₂) to develop a bluish colour reaction with the absorption maxima centred at 652 nm. The CuO NPs exhibited better kinetics over horseradish peroxidase (HRP), the natural enzyme, with a lower Km value. Linear response range for glucose, was 10 – 100 µM and a limit of detection (5.06 µM) was obtained.</p></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"35 6","pages":"2093 - 2103"},"PeriodicalIF":2.7,"publicationDate":"2024-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141254544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immobilization of Ficin Enzyme onto Surface-Modified Iron Oxide Nanoparticles: Characterization and Catalytic Activity","authors":"Shahrzad Barani Shooli,&nbsp;Mahmood Aminlari,&nbsp;Shahriyar Sahraeian,&nbsp;Sedigheh Zeinali,&nbsp;Mehrdad Niakousari","doi":"10.1007/s10876-024-02612-1","DOIUrl":"10.1007/s10876-024-02612-1","url":null,"abstract":"<div><p>Biocatalytic performance of immobilized ficin onto silica-coated iron oxide magnetic nanoparticles (MNPs) was examined. FTIR study indicated the successful immobilization of ficin onto silica-coated MNPs. The MNPs were synthesized by an ultrasonic-assisted sol-gel method, resulting in coarse silica-coated MNPs with an amorphous or nanocrystalline phase. Results showed that the affinity of ficin to the substrate decreased due to the immobilization. However, the immobilized ficin exhibited enhanced stability and catalytic activity, with a wider pH range and higher thermal stability compared to free ficin. The optimum pH for immobilized ficin activity was found to be shifted from 7.0 to 6.0, making it a suitable candidate for slight acidic conditions. After five days of storage, immobilized ficin retained its initial activity, while free ficin showed a 30% decrease in activity. The immobilized ficin also exhibited a substantially higher activity than its free form after multiple cycles of usage. These findings suggest that immobilized ficin onto silica-coated iron oxide MNPs is a promising candidate for biocatalysis and industrial processes in a wide range of temperature and solutions with high reusability and stability.</p></div>","PeriodicalId":618,"journal":{"name":"Journal of Cluster Science","volume":"35 6","pages":"2081 - 2092"},"PeriodicalIF":2.7,"publicationDate":"2024-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141259605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}