{"title":"A Robust Higher-Order Scheme for Fractional Delay Differential Equations Involving Caputo Derivative","authors":"Biswajit Prusty, Madhukant Sharma","doi":"10.1007/s40995-024-01695-9","DOIUrl":"10.1007/s40995-024-01695-9","url":null,"abstract":"<div><p>This article considers nonlinear fractional delay differential equations involving Caputo’s fractional derivative of order <span>(alpha in (0,1))</span>. We focus on designing a robust numerical algorithm of order <span>(O(h^{4-alpha }))</span>. To achieve this, we developed a higher-order interpolation-based approximation for Caputo’s derivative, which enables us to construct a robust numerical scheme for the considered problem. Furthermore, we discuss the stability and error analysis of the proposed higher-order scheme. Finally, numerous examples, including real-life applications, are evaluated to demonstrate the computational efficiency of the proposed algorithm.</p></div>","PeriodicalId":600,"journal":{"name":"Iranian Journal of Science and Technology, Transactions A: Science","volume":"48 6","pages":"1561 - 1577"},"PeriodicalIF":1.4,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142216102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shivam Srivastava, Prachi Singh, Anjani Kumar Pandey, Chandra Kumar Dixit
{"title":"Investigations of Thermo-Elastic Properties of Mono Atomic and Diatomic Solids at High Pressure Using New EOS","authors":"Shivam Srivastava, Prachi Singh, Anjani Kumar Pandey, Chandra Kumar Dixit","doi":"10.1007/s40995-024-01690-0","DOIUrl":"10.1007/s40995-024-01690-0","url":null,"abstract":"<div><p>In this theoretical research, we have derived new equation of state (EOS) based on empirical concepts. This new EOS is suitable at high as well as low compression ranges for solids. In this study, pressure and bulk modulus of different solids have been established at high pressure. In the theoretical study four different solids viz. MgO, LiF, Ne and Ar have been considered. The exact matching of our work with previous workers leads to the conclusion that the new EOS can be used for calculating the thermo elastic properties of different solids.</p></div>","PeriodicalId":600,"journal":{"name":"Iranian Journal of Science and Technology, Transactions A: Science","volume":"48 6","pages":"1663 - 1668"},"PeriodicalIF":1.4,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142216222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Hussain, M. U. Manzoor, M. Kamran, F. Riaz, M. Ammar, A. Mansoor, H. M. R. Tariq, M. H. Hassan, M. Ishtiaq
{"title":"The Effect of Surface Roughness and Deposition Time on the Biocompatibility of Electrodeposited Hydroxyapatite Coating on Grit-Blasted AZ31B Mg Alloy","authors":"F. Hussain, M. U. Manzoor, M. Kamran, F. Riaz, M. Ammar, A. Mansoor, H. M. R. Tariq, M. H. Hassan, M. Ishtiaq","doi":"10.1007/s40995-024-01701-0","DOIUrl":"10.1007/s40995-024-01701-0","url":null,"abstract":"<div><p>Magnesium alloys have demonstrated tremendous potential as bio-implants due to their superior biomedical properties. This study examines the influence of surface roughness on the electrodeposition of Hydroxyapatite (HA) coatings on AZ31B magnesium alloy samples. We investigated samples grit-blasted with quartz and alumina at various pressures and compared them with un-blasted samples to ensure a comprehensive analysis across different deposition times. Higher blasting pressure resulted in increased surface roughness. Overall, samples blasted with alumina exhibited greater surface roughness and thicker coatings. X-ray diffraction (XRD)analysis confirmed the presence of HA coatings. Scanning electron microscope (SEM) analysis revealed that HA coating thickness increased with longer deposition times. Open circuit potential (OCP) measurements indicated that alumina-blasted samples showed nearly complete coverage with a 10-minute HA deposition at 700 kPa (approximately − 0.336 V), with increased compactness and more positive OCP values observed with longer deposition times. Complete insulated coverage was achieved at 40 min, with OCP values of -0.075 V at 700 kPa and − 0.049 V at 1000 kPa. Statistical analysis using ANOVA demonstrated that both blasting pressure and deposition time significantly impact coating thickness, with blasting pressure having a primary effect on OCP. Higher OCP values indicated a 95% increase in corrosion resistance at a blasting pressure of 1000 kPa and a 40-minute deposition time for alumina-blasted samples. The Ca/P ratio (∼ 1.67) and XRD patterns consistently confirmed the HA phase.</p></div>","PeriodicalId":600,"journal":{"name":"Iranian Journal of Science and Technology, Transactions A: Science","volume":"49 1","pages":"283 - 296"},"PeriodicalIF":1.4,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s40995-024-01701-0.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142216103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hüseyin Izgördü, Canan Vejselova Sezer, Nesil Ertorun, Hatice Mehtap Kutlu
{"title":"Exploring the Antiproliferative, Cytotoxic and Proapoptotic Properties of Virkon-S in Carp Epithelioma Papulosum Cells","authors":"Hüseyin Izgördü, Canan Vejselova Sezer, Nesil Ertorun, Hatice Mehtap Kutlu","doi":"10.1007/s40995-024-01692-y","DOIUrl":"10.1007/s40995-024-01692-y","url":null,"abstract":"<div><p><i>Cyprinus carpio</i> is one of most produced fish species farmed in Turkey. There are many factors comprising with the viral diseases that reduce productivity and cause significant economic losses in carp production. <i>Epithelioma papulosum cyprini</i> (EPC) is of the viral diseases with high infection and mortality rates. For prevention of parasitic diseases disinfectants have been used but due to the potential genotoxicity and cytotoxic effects alternative non-toxic agents are required. The biocompatible, and non-toxic disinfectant Virkon-S is recommended by FAO for this manner but its application on <i>Epithelioma papulosum cyprini</i>, but its usage on this disease has not yet been researched. The aim of this study was to investigate the cytotoxic, antiproliferative and proapoptotic effects of Virkon-S on EPC cells. Cytotoxicity, morphological and ultrastructural changes were investigated by MTT assay, confocal and transmission electron microscopy (TEM) techniques. Cell death mode was investigated by Annexin-V and Caspase 3/7 analysis. Cytotoxicity and apoptosis was detected on Virkon-S treated EPC cells. Also, TEM results revealed that Virkon-S notably changed the ultrastructure of EPC cells together with indications like swollen mitochondria, loss of cristae and membrane blebbings. The study results showed that Virkon-S has cytotoxic, antiproliferative and proapoptotic effects on EPC cells and might be used for prevention of EPC disease after deeper <i>in vivo</i> investigations. These findings collectively suggest the induction of cytotoxicity on the cellular ultrastructure. Furthermore, in alignment with the findings from confocal microscopy, it can be concluded that Virkon-S triggers apoptosis in EPC cells.</p></div>","PeriodicalId":600,"journal":{"name":"Iranian Journal of Science and Technology, Transactions A: Science","volume":"48 5","pages":"1125 - 1133"},"PeriodicalIF":1.4,"publicationDate":"2024-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142216104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rizwan Ullah Khan, Sidra Mumtaz, Muhammad Imran Sohail, Naila Malkani
{"title":"Assessing Regulation of ERG and its Target Proteins by ERG Isoform 8","authors":"Rizwan Ullah Khan, Sidra Mumtaz, Muhammad Imran Sohail, Naila Malkani","doi":"10.1007/s40995-024-01683-z","DOIUrl":"10.1007/s40995-024-01683-z","url":null,"abstract":"<div><p>Ets-related gene (ERG) is a key protein in vascular homeostasis. It has multiple isoforms. These isoforms have predominant nuclear localization except ERG isoform 8. This isoform can modify the nuclear localization of other isoforms and can down-regulate other isoforms. However, the mechanism of this regulation and its impact on ERG target proteins is still unclear. This study is designed to analyze the effects of ERG8 on functional aspects of other isoforms. For this purpose, the expressions of ERG3 target genes; VE-cad, sox4, cxcr4 were analyzed after ERG8 and ERG3 co-transfection. Increasing ERG8 to ERG3 ratios were transfected in 293-HEK cells. qPCR analysis was performed on total RNA extracted from transfected cells to evaluate the changes in expression of target genes. Results showed that ERG3 alone significantly increased the expression of these target genes (p˂0.05). However, the increasing concentrations of ERG8 progressively decreased the expression of the target genes significantly (p˂0.05). For in silico prediction of the nature of ERG3-ERG8 interaction, their three-dimensional models were built using I-TASSER and interaction was predicted using HADDOCK 2.4. HADDOCK scores show that ERG8 via its pointed (PNT) domain can interact with Ets domain of ERG3 (HADDOCK score; -28.956 +/- 15.881) as well as PNT domain (HADDOCK score; -4.426 +/- 7.770). Our results indicate that ERG8 affect the transcription factor activity of ERG3 by hindering its binding with the DNA either through PNT or Ets domain</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":600,"journal":{"name":"Iranian Journal of Science and Technology, Transactions A: Science","volume":"48 5","pages":"1081 - 1086"},"PeriodicalIF":1.4,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142216105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Aslam Siddeeque, Raof Ahmad Bhat, Abbas Hussain Shikeh
{"title":"Nonlinear Maps Preserving the Mixed Type Product ((Mdiamond N circ W)) on (*)-Algebras","authors":"Mohammad Aslam Siddeeque, Raof Ahmad Bhat, Abbas Hussain Shikeh","doi":"10.1007/s40995-024-01666-0","DOIUrl":"10.1007/s40995-024-01666-0","url":null,"abstract":"<div><p>Let <span>({mathcal {S}})</span> and <span>({mathfrak {B}})</span> be two unital <span>(*)</span>-algebras such that <span>({mathcal {S}})</span> has a nontrivial projection. In the present article, we demonstrate, under certain restrictions that if a bijective map <span>(Delta :{mathcal {S}}rightarrow {mathfrak {B}})</span> satisfies <span>(Delta (Mdiamond N circ W) = Delta (M)diamond Delta (N)circ Delta (W))</span> for all <span>(M, N, W in {mathcal {S}})</span>, then <span>(Delta)</span> is a <span>(*)</span>-preserving ring isomorphism. As an application, we will describe these mappings on factor von Neumann algebras.</p></div>","PeriodicalId":600,"journal":{"name":"Iranian Journal of Science and Technology, Transactions A: Science","volume":"48 5","pages":"1307 - 1312"},"PeriodicalIF":1.4,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142216108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samir M. El Rayes, Ibrahim A. I. Ali, Walid Fathalla, Mohamed A. Ghanem, Afaf H. El-Sagheer, Mohamed S. Nafie
{"title":"Synthesis of Trifluoromethyl Benzimidazoles with Potential Anti-Microbial Activities","authors":"Samir M. El Rayes, Ibrahim A. I. Ali, Walid Fathalla, Mohamed A. Ghanem, Afaf H. El-Sagheer, Mohamed S. Nafie","doi":"10.1007/s40995-024-01664-2","DOIUrl":"10.1007/s40995-024-01664-2","url":null,"abstract":"<div><p>A series of twenty-two new trifloromethyl benzimidazole derivatives were prepared based on azide and DCC coupling of 2-(2-(trifluoromethyl)-1<i>H</i>-benzoimidazol-1-yl) ethanoic acid derivatives with amino acids to give the amino acid esters; methyl 2-[(2-(2-(trifluoromethyl)-1<i>H</i>-benzimidazol-1-yl)acetamido] alkanoates. The amino acid esters reacted with hydrazine to produce the corresponding hydrazides that were finally condensed with <i>p</i>-fluorobenzaldehyde to obtain the hydrazones. The synthesized compounds were evaluated for their ability to bind to the crystal structure of <i>E. coli</i> (PDB = 1KZN) and the crystal structure of <i>S. aureus</i> (PDB = 1JIJ) bacteria, revealing good binding affinities. Notably, compounds <b>5e</b> and <b>5k</b> demonstrated primising interactive binding mode with the key amino acids like the co-crystallized ligands. As a result, they can be further tested as potent antimicrobial agents.</p></div>","PeriodicalId":600,"journal":{"name":"Iranian Journal of Science and Technology, Transactions A: Science","volume":"49 1","pages":"21 - 32"},"PeriodicalIF":1.4,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142216149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optimal Convergence of Thermoelastic Contact Problem Involving Nonlinear Hencky-Type Materials with Friction Conditions","authors":"H. EL Khalfi, Z. Faiz, O. Baiz, H. Benaissa","doi":"10.1007/s40995-024-01677-x","DOIUrl":"10.1007/s40995-024-01677-x","url":null,"abstract":"<div><p>We study the linear finite element approximation of thermoelastic frictional contact problem. The unilateral contact condition is weakly imposed by the penalty method. Our analysis yields error estimates that are contingent upon the penalty parameter <span>(varepsilon)</span> and the mesh size <i>h</i>. Furthermore, provided the solution maintains regularity, we establish a convergence result.</p></div>","PeriodicalId":600,"journal":{"name":"Iranian Journal of Science and Technology, Transactions A: Science","volume":"49 1","pages":"133 - 149"},"PeriodicalIF":1.4,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141938919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Numerical Solution of Stochastic Fractional Integro-Differential Equations: The Poly-sinc Collocation Approach","authors":"Faezeh Bahmani, Ali Eftekhari","doi":"10.1007/s40995-024-01672-2","DOIUrl":"10.1007/s40995-024-01672-2","url":null,"abstract":"<div><p>This paper presents a polynomial sinc-based collocation method, combined with Gauss–Legendre/Newton–Cotes quadrature rules, to solve stochastic fractional integro-differential equations (SFIDEs). The method approximates the solution by applying Lagrangian polynomial interpolation at sinc collocation points and simplifies the SFIDE into a system of algebraic equations, requiring low/moderate computational efforts. The proposed method is also accompanied by an error analysis, and numerical examples are provided to demonstrate its efficiency and accuracy. In noiseless conditions, the method achieves spectral accuracy and behaves like other conventional sinc methods. Finally, the paper simulates an application of a class of these equations.</p></div>","PeriodicalId":600,"journal":{"name":"Iranian Journal of Science and Technology, Transactions A: Science","volume":"49 1","pages":"117 - 132"},"PeriodicalIF":1.4,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141882579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Novel Operational Matrix Method for Solving the Fractional Delay Integro-Differential Equations with a Weakly Singular Kernel","authors":"S. Yaghoubi, H. Aminikhah, K. Sadri","doi":"10.1007/s40995-024-01682-0","DOIUrl":"10.1007/s40995-024-01682-0","url":null,"abstract":"<div><p>In this work, we introduce a feasible and efficient method for solving weakly singular fractional pantograph delay integro-differential equations. To implement the proposed method, we get the operational matrices based on the shifted fractional-order fifth-kind Chebyshev polynomials. These matrices, together with the collocation method, are applied to convert the main equation to a system of algebraic equations. We consider the existence and uniqueness of solutions and then give an upper error bound for this method. At last, several numerical tests are carried out to demonstrate the usefulness and capability of the suggested algorithm.</p></div>","PeriodicalId":600,"journal":{"name":"Iranian Journal of Science and Technology, Transactions A: Science","volume":"48 6","pages":"1595 - 1611"},"PeriodicalIF":1.4,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141870668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}