Cranio-The Journal of Craniomandibular & Sleep Practice最新文献

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The relationship between aerodynamic characteristics of the upper airway and severity of obstructive sleep apnea in adults. 成人上呼吸道空气动力学特征与阻塞性睡眠呼吸暂停严重程度的关系。
IF 2 4区 医学
Cranio-The Journal of Craniomandibular & Sleep Practice Pub Date : 2025-07-01 Epub Date: 2023-11-19 DOI: 10.1080/08869634.2023.2278958
Xiaoya Wang, Lu Jia, Xin Xu, Jing Guo
{"title":"The relationship between aerodynamic characteristics of the upper airway and severity of obstructive sleep apnea in adults.","authors":"Xiaoya Wang, Lu Jia, Xin Xu, Jing Guo","doi":"10.1080/08869634.2023.2278958","DOIUrl":"10.1080/08869634.2023.2278958","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the relationship between aerodynamic characteristics of the upper airway and severity of obstructive sleep apnea (OSA) in adults.</p><p><strong>Methods: </strong>Ninety-seven adult OSA patients underwent polysomnography and cone beam computed tomography (CBCT). The anatomical and aerodynamic characteristics were measured based on CBCT images and computational fluid dynamics modelling of the upper airway.</p><p><strong>Results: </strong>After controlling for patients' gender, age, and body mass index (BMI), the maximum velocity during inspiration (In-Vmax) led to the largest increase in the explanatory power of apnea-hypopnea index (AHI) variation. The In-Vmax was closely correlated with the minimum axial area, and their relationship was represented by an inversely proportional fitted curve.</p><p><strong>Conclusions: </strong>The In-Vmax was the most relevant to OSA severity, and it could be used to assist in recognizing severe OSA patients and as a primary variable to evaluate treatment outcomes of OSA. The In-Vmax was closely related to the most constricted area of the upper airway.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"646-653"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138048931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Central effects of trigeminal electrical stimulation. 三叉神经电刺激的中枢效应。
IF 2 4区 医学
Cranio-The Journal of Craniomandibular & Sleep Practice Pub Date : 2025-07-01 Epub Date: 2023-11-30 DOI: 10.1080/08869634.2023.2280153
Annalisa Monaco, Ruggero Cattaneo, Sara Di Nicolantonio, Marco Strada, Serena Altamura, Eleonora Ortu
{"title":"Central effects of trigeminal electrical stimulation.","authors":"Annalisa Monaco, Ruggero Cattaneo, Sara Di Nicolantonio, Marco Strada, Serena Altamura, Eleonora Ortu","doi":"10.1080/08869634.2023.2280153","DOIUrl":"10.1080/08869634.2023.2280153","url":null,"abstract":"<p><p>This is a review of the literature on the main neuromodulation techniques, focusing on the possibility of introducing sensory threshold ULFTENS into them. Electro neuromodulation techniques have been in use for many years as promising methods of therapy for cognitive and emotional disorders. One of the most widely used forms of stimulation for orofacial pain is transcutaneous trigeminal stimulation on three levels: supraorbital area, dorsal surface of the tongue, and anterior skin area of the tragus. The purpose of this review is to trigger interest on using dental ULFTENS as an additional trigeminal neurostimulation and neuromodulation technique in the context of TMD. In particular, we point out the possibility of using ULFTENS at a lower activation level than that required to trigger a muscle contraction that is capable of triggering effects at the level of the autonomic nervous system, with extreme ease of execution and few side effects.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"654-677"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138464680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of temporomandibular disorders in the Brazilian population: A systematic review and meta-analysis. 巴西人群中颞下颌疾病的患病率:系统回顾和荟萃分析。
IF 2 4区 医学
Cranio-The Journal of Craniomandibular & Sleep Practice Pub Date : 2025-07-01 Epub Date: 2023-11-13 DOI: 10.1080/08869634.2023.2276627
Vítor Melo, Larissa Monteiro, Carolina Orge, Matheus Sales, Juliana Melo, Bernardo Rodrigues, Ailton Melo
{"title":"Prevalence of temporomandibular disorders in the Brazilian population: A systematic review and meta-analysis.","authors":"Vítor Melo, Larissa Monteiro, Carolina Orge, Matheus Sales, Juliana Melo, Bernardo Rodrigues, Ailton Melo","doi":"10.1080/08869634.2023.2276627","DOIUrl":"10.1080/08869634.2023.2276627","url":null,"abstract":"<p><p>This systematic review aimed to assess the prevalence of temporomandibular disorders (TMD) in the Brazilian population, with studies that used the RDC/TMD or DC/TMD as diagnostic tools. A total of 6365 people from 11 studies were included. Sample mean age ranged from 12 to 69.5 years. The pooled prevalence of TMD was 33.6% (95% CI 31.5-35.8; I<sup>2</sup> = 37.2). Prevalence of TMD was higher in females (37.0%) than in males (29.3%). Our results indicate that TMD is a prevalent condition across Brazil's territories. The results from this meta-analysis can help calculate more accurate sample sizes for future studies.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"629-636"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89720825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The relation of temporomandibular disorders with oral health-related quality of life in the Northern Finland Birth Cohort 1966. 1966年北芬兰出生队列中颞下颌关节紊乱与口腔健康相关生活质量的关系。
IF 2 4区 医学
Cranio-The Journal of Craniomandibular & Sleep Practice Pub Date : 2025-07-01 Epub Date: 2023-06-21 DOI: 10.1080/08869634.2023.2226829
Elisa Tervahauta, Ritva Näpänkangas, Linnea Närhi, Mimmi Tolvanen, Pertti Pirttiniemi, Anna-Sofia Silvola, Kirsi Sipilä
{"title":"The relation of temporomandibular disorders with oral health-related quality of life in the Northern Finland Birth Cohort 1966.","authors":"Elisa Tervahauta, Ritva Näpänkangas, Linnea Närhi, Mimmi Tolvanen, Pertti Pirttiniemi, Anna-Sofia Silvola, Kirsi Sipilä","doi":"10.1080/08869634.2023.2226829","DOIUrl":"10.1080/08869634.2023.2226829","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the association between temporomandibular disorders (TMD) and oral health-related quality of life (OHRQoL) in an adult population.</p><p><strong>Methods: </strong>The data included 1,768 adults 46 years of age in the Northern Finland Birth Cohort 1966 (NFBC1966) study. The symptoms, signs and diagnoses of TMD were assessed using a modified protocol of the Diagnostic Criteria for TMD (DC/TMD) and validated questionnaires. OHRQoL was measured using the Oral Health Impact Profile (OHIP-14). Associations of TMD and OHRQoL were evaluated with χ<sup>2</sup> -test and Fisher's exact test.</p><p><strong>Results: </strong>In females, pain-related TMD signs and diagnoses associated significantly with prevalence of OHIP total and all dimensions, whereas in joint-related TMD, psychological dimensions showed the strongest association. Males with pain- or joint-related TMD, the most impaired dimension was physical pain.</p><p><strong>Conclusion: </strong>Pain-related TMD seems to associate more strongly with lower OHRQoL than joint-related TMD especially in females.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"577-587"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9881440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reliability of Friedman Staging System and Modified Mallampati Scoring as clinical assessment methods for Obstructive Sleep Apnea - A cross sectional study. Friedman分期系统和改良Mallampati评分作为阻塞性睡眠呼吸暂停临床评估方法的可靠性-一项横断面研究。
IF 2 4区 医学
Cranio-The Journal of Craniomandibular & Sleep Practice Pub Date : 2025-07-01 Epub Date: 2023-06-22 DOI: 10.1080/08869634.2023.2221618
Deepika J Nair, Sapna N K Varma, Parvathy Ghosh, V V Ajith
{"title":"Reliability of Friedman Staging System and Modified Mallampati Scoring as clinical assessment methods for Obstructive Sleep Apnea - A cross sectional study.","authors":"Deepika J Nair, Sapna N K Varma, Parvathy Ghosh, V V Ajith","doi":"10.1080/08869634.2023.2221618","DOIUrl":"10.1080/08869634.2023.2221618","url":null,"abstract":"<p><strong>Objective: </strong>To assess the utility of oropharyngeal crowding indicators as predictors of Obstructive Sleep Apnea (OSA).</p><p><strong>Methods: </strong>STOP-BANG Questionnaire was administered to 145 adults. Of the 95 with high OSA risk, 42 underwent polysomnography. Intraoral space was assessed using modified Mallampati (MMP) and Friedman Scoring (FS) System.</p><p><strong>Results: </strong>Twenty-four were found to have OSA by polysomnography. Most with low risk (86%) had only Class I MMP. Whereas Class III and IV were seen in 37.9% and 17.9% patients with high risk (<i>p</i> < .001) and 50% and 20.8% patients with OSA (<i>p</i> < .831), respectively. All with low risk had Stage 1 FS. Stages 3 and 4 were observed in 27.4% and 1.1% in the high-risk group (<i>p</i> < .001) and in 29.2% and 4.2% with OSA (<i>p</i> < .092), respectively.</p><p><strong>Conclusion: </strong>In limited settings, either MMP or FS scores along with the STOP-BANG questionnaire can be used to diagnose OSA.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"543-550"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9671418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The prevalence of bruxism and oral parafunction activities among Israeli juveniles with autism spectrum disorder: A preliminary study during the COVID-19 pandemic. 以色列自闭症谱系障碍青少年中磨牙和口腔功能障碍的患病率:2019冠状病毒病大流行期间的初步研究
IF 2 4区 医学
Cranio-The Journal of Craniomandibular & Sleep Practice Pub Date : 2025-07-01 Epub Date: 2023-11-14 DOI: 10.1080/08869634.2023.2277618
Orit Winocur-Arias, Bat-Chen Amitai, Efraim Winocur, Tom Shmuly, Osnat Grinstein Koren, Shoshana Reiter
{"title":"The prevalence of bruxism and oral parafunction activities among Israeli juveniles with autism spectrum disorder: A preliminary study during the COVID-19 pandemic.","authors":"Orit Winocur-Arias, Bat-Chen Amitai, Efraim Winocur, Tom Shmuly, Osnat Grinstein Koren, Shoshana Reiter","doi":"10.1080/08869634.2023.2277618","DOIUrl":"10.1080/08869634.2023.2277618","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the prevalence of oral habits, bruxism, and Temporomandibular Disorders (TMD) injuvenileswithautisticspectrumdisorder(ASD).</p><p><strong>Methods: </strong>Data included 165 juveniles diagnosed with ASD, allocated to younger group aged 6 21 (n=86) and older group aged 13-21 (n=79).</p><p><strong>Results: </strong>Sleep bruxism was reported by 26.7% in the younger group and by 5% in the older group. Awake bruxism was reported by 22% and 17.7%, respectively. Oral habits were reported by 43% of all participants, with similar rate in both groups. TMD related p ain was low in both groups (6.3% and 7% respectively). The influence of the COVID 19 pandemic on oral parafunction was moderate in the younger group (17.4%) and mild in the older group (8.6%), influence on bruxism was mild in both groups (5.8% and 2.5%, respectively).</p><p><strong>Conclusion: </strong>The prevalence of bruxism and oral parafunctions was similar to the reported in the literature for the general population.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"637-645"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107592961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The efficacy of orofacial myofunctional therapy in oral dysphagia accompanying temporomandibular dysfunction. 口面肌功能治疗口腔吞咽困难伴颞下颌功能障碍的疗效观察。
IF 2 4区 医学
Cranio-The Journal of Craniomandibular & Sleep Practice Pub Date : 2025-07-01 Epub Date: 2023-06-21 DOI: 10.1080/08869634.2023.2226832
Hazel Çelik Güzel, Aysenur Tuncer
{"title":"The efficacy of orofacial myofunctional therapy in oral dysphagia accompanying temporomandibular dysfunction.","authors":"Hazel Çelik Güzel, Aysenur Tuncer","doi":"10.1080/08869634.2023.2226832","DOIUrl":"10.1080/08869634.2023.2226832","url":null,"abstract":"<p><strong>Objective: </strong>Patients with temporomandibular dysfunction (TMD) may develop oral-stage dysphagia (OD) in the chronic phase.</p><p><strong>Methods: </strong>This study investigated the effect of orofacial myofunctional therapy (OMT) in individuals with TMD-related OD. Fifty-one patients aged 18-65 years with TMD-related OD were separated into three groups using a simple randomization method: the control group (<i>n</i> = 12) underwent patient education and a home-exercise program; additionally, to an exercise program the manual therapy (MT) group (<i>n</i> = 19) received MT; and the OMT group (<i>n</i> = 20) received the OMT program. MT and OMT were applied in two sessions per week for 10 weeks. The patients were re-evaluated after treatment and at 3 months.</p><p><strong>Results: </strong>The OMT group showed the most improvement in jaw functionality, swallowing-related quality of life, pain, and dysphagia (<i>p</i> < .05).</p><p><strong>Discussion: </strong>OMT was superior to MT and exercises alone in reducing dysphagia and improving the swallowing-related quality of life.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"588-598"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9673604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of maximum mouth opening in terms of age, weight, height and body mass index in Turkish adult population. 土耳其成人年龄、体重、身高和体质指数对最大开口的调查。
IF 2 4区 医学
Cranio-The Journal of Craniomandibular & Sleep Practice Pub Date : 2025-07-01 Epub Date: 2023-06-21 DOI: 10.1080/08869634.2023.2226828
Mehmet Gökhan Demir
{"title":"Investigation of maximum mouth opening in terms of age, weight, height and body mass index in Turkish adult population.","authors":"Mehmet Gökhan Demir","doi":"10.1080/08869634.2023.2226828","DOIUrl":"10.1080/08869634.2023.2226828","url":null,"abstract":"<p><strong>Introduction: </strong>Maximum mouth opening (MMO) is an important finding in the detection of many diseases and conditions.The aim of this study is to determine the relationship of MMO level with age, gender, weight, height, BMI variables in adult individuals.</p><p><strong>Materials and methods: </strong>A total of 1582 participants, 806 women and 756 men, between the ages of 18-85 were included in the study. MMO, age, gender, weight, height and BMI values of the participants were recorded.</p><p><strong>Results: </strong>Among the 1582 participants included in the study, the MMO value of men was 44.2 mm, while it was 40.29 mm in women. The MMO value of men was found to be higher than that of women (<i>p</i> < .05). A correlation was observed between MMO and height (<i>p</i> < .05).</p><p><strong>Conclusions: </strong>In the study, a correlation was observed between MMO and height. The MMO value was found to be higher in men.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"571-576"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9673605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Age distribution of East Asian TMD patients and age-related differences in DC/TMD axis I findings. 东亚 TMD 患者的年龄分布和 DC/TMD 轴 I 发现的年龄相关差异。
IF 2 4区 医学
Cranio-The Journal of Craniomandibular & Sleep Practice Pub Date : 2025-07-01 Epub Date: 2024-02-18 DOI: 10.1080/08869634.2024.2316081
Adrian Ujin Yap, Jie Lei, Ji Woon Park, Chengge Liu, Seong Hae Kim, Byeong-Min Lee, Kai-Yuan Fu
{"title":"Age distribution of East Asian TMD patients and age-related differences in DC/TMD axis I findings.","authors":"Adrian Ujin Yap, Jie Lei, Ji Woon Park, Chengge Liu, Seong Hae Kim, Byeong-Min Lee, Kai-Yuan Fu","doi":"10.1080/08869634.2024.2316081","DOIUrl":"10.1080/08869634.2024.2316081","url":null,"abstract":"<p><strong>Objectives: </strong>The pattern of age distribution in East Asian temporomandibular disorder (TMD) patients and age-related differences in DC/TMD diagnostic subtypes/categories were evaluated.</p><p><strong>Subjects and methods: </strong>TMD patients from two University-based centers in China and South Korea were enrolled. Axis I physical diagnoses were rendered according to DC/TMD. Patients were categorized into six age groups (15-24, 25-34, 35-44, 45-54, 55-64, and 65-84 years; Groups A-F respectively).</p><p><strong>Results: </strong>Youths/young adults (Groups A-C) formed 74.1% of TMD patients. TMJ disc displacements (74.9%), arthralgia (49.2%), and degenerative joint disease [DJD] (36.8%) were the most common TMD subtypes. The majority had combined (54.0%) and chronic (58.5%) TMDs. Youths/young adults and middle-aged/old adults had substantially lower frequencies of merely pain-related (6.2-14.5%) and intra-articular (13.8-16.8%) TMDs correspondingly. \"Being female\" increased the prospects of pain-related/combined TMDs by 96%/49%, respectively.</p><p><strong>Conclusions: </strong>East Asian TMD patients comprised mostly of youths/young adults who had an alarmingly high prevalence of TMJ DJD.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"688-697"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139900936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Salivary biomarkers as potential diagnostic tool for temporomandibular disorders: A comprehensive review. 唾液生物标志物作为颞下颌疾病的潜在诊断工具:全面回顾。
IF 2 4区 医学
Cranio-The Journal of Craniomandibular & Sleep Practice Pub Date : 2025-07-01 Epub Date: 2023-07-12 DOI: 10.1080/08869634.2023.2229607
Yasmina Aoun, Rita Ejbeh, Abboud Youssef, Joseph Hobeiche
{"title":"Salivary biomarkers as potential diagnostic tool for temporomandibular disorders: A comprehensive review.","authors":"Yasmina Aoun, Rita Ejbeh, Abboud Youssef, Joseph Hobeiche","doi":"10.1080/08869634.2023.2229607","DOIUrl":"10.1080/08869634.2023.2229607","url":null,"abstract":"<p><strong>Objective: </strong>To review the current scientific literature concerning the implication of biomarkers collected from saliva in the diagnosis of temporomandibular disorders (TMD).</p><p><strong>Methods: </strong>A comprehensive literature search was conducted on PubMed, Google Scholar, Embase, MEDLINE and Web of Science to gather articles published between 2012 and 2021. Based on the eligibility criteria, articles were reviewed in full and precise data was extracted.</p><p><strong>Results: </strong>Nine clinical studies were selected. Participants with TMD were all diagnosed according to the Diagnostic Criteria for Temporomandibular Disorders. Specific biomarkers were examined from saliva samples. Results related to TMD showed a significant range of variability.</p><p><strong>Conclusion: </strong>Specific salivary biomarkers have been investigated, but current efforts are aiming to search for more possible biomarkers from saliva samples as a safe procedure. Future research needs to consider the sensitivity and specificity of these biomarkers as diagnostic tools for TMD.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"603-612"},"PeriodicalIF":2.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9826973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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