Oguzhan Ilden, Omer Tarik Selcuk, Hamit Yasar Ellidag, Nursel Türkoglu Selcuk, Hulya Eyigor, Levent Renda, Unal Gökalp Isik, Hande Konsuk Unlü, Ustün Osma, Mustafa Deniz Yılmaz, Esin Eren, Necat Yilmaz
{"title":"An evaluation of the change in serum SCUBE-1 levels with CPAP treatment in patients with severe obstructive sleep apnea.","authors":"Oguzhan Ilden, Omer Tarik Selcuk, Hamit Yasar Ellidag, Nursel Türkoglu Selcuk, Hulya Eyigor, Levent Renda, Unal Gökalp Isik, Hande Konsuk Unlü, Ustün Osma, Mustafa Deniz Yılmaz, Esin Eren, Necat Yilmaz","doi":"10.1080/08869634.2022.2145710","DOIUrl":"10.1080/08869634.2022.2145710","url":null,"abstract":"<p><strong>Objective: </strong>Signal peptide CUB-EGF domain-containing protein 1 (SCUBE-1) is a cell surface protein, wherein inflammation causes an increase in serum. The aim of this study was to compare serum SCUBE-1 levels in OSA patients and to investigate the serum SCUBE-1 change with CPAP treatment.</p><p><strong>Methods: </strong>Blood samples were obtained from 61 severe OSA patients and from 25 control subjects evaluated as simple snorers. The 61 patients with severe OSA were treated with CPAP therapy and were recalled for follow up after 1 year. Evaluation was made after 1 year of CPAP therapy.</p><p><strong>Results: </strong>Serum SCUBE-1 values were significantly higher in patients with severe OSA. The SCUBE-1 values significantly decreased after treatment with CPAP.</p><p><strong>Conclusion: </strong>Serum SCUBE-1 values in OSA patients showed a significant reduction in SCUBE-1 levels following 1 year of CPAP treatment.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"410-416"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10682865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Glaucia Marques Dias, Eduardo Grossmann, Antonio Carlos Pires Carvalho, Karina Lopes Devito, Marcos Fabio Dos Santos, Luciano Ambrosio Ferreira
{"title":"MRI changes and clinical characteristics in temporomandibular joints with displacement of the articular disk without reduction - a cross-sectional observational study.","authors":"Glaucia Marques Dias, Eduardo Grossmann, Antonio Carlos Pires Carvalho, Karina Lopes Devito, Marcos Fabio Dos Santos, Luciano Ambrosio Ferreira","doi":"10.1080/08869634.2023.2203039","DOIUrl":"10.1080/08869634.2023.2203039","url":null,"abstract":"<p><strong>Objectives: </strong>This study examined changes in magnetic resonance imaging (MRI) of temporomandibular joints (TMJ) with anterior displacement disk without reduction (DDwoR) and its correlation to clinical symptoms.</p><p><strong>Methods: </strong>190 individuals with DDwoR were evaluated according to Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) and MRI. Pain's chronicity/intensity and limited mouth opening (locking) were correlated with: TMJ degeneration (MRI T1), effusion (T2), disc's shape and position (proton density).</p><p><strong>Results: </strong>In 103 TMJ with DDwoR, hemiconvex shape (41.6%), sclerosis (45.6%) and mild effusion (47.6%) were the most prevalent findings. There was not association (<i>p</i> > .05) between: different DDwoR positions with pain's intensity/chronicity; effusion with locking. Disk deformation was associated with degeneration (<i>p</i> = .034) and pain's intensity (<i>p</i> = .006). Locking was associated with degeneration (<i>p</i> = .05).</p><p><strong>Conclusions: </strong>Condylar osteodegeneration is often related to DDwoR. Locking by DDwoR is associated with severe levels of chronic pain and articular disk deformation.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"521-530"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9344148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Use of the Depression Anxiety Stress Scale-21 in young people with temporomandibular disorders: Reliability and dimensionality.","authors":"Adrian Ujin Yap, Darren Zong Ru Lee","doi":"10.1080/08869634.2022.2158259","DOIUrl":"10.1080/08869634.2022.2158259","url":null,"abstract":"<p><strong>Objective: </strong>The reliability and dimensionality of the Depression Anxiety Stress Scale-21 (DASS-21) were explored in adolescents/young adults with temporomandibular disorders (TMDs).</p><p><strong>Methods: </strong>TMD presence was established with the Fonseca Anamnestic Index. Reliability of the DASS-21 for participants with (WT) and without (NT) TMDs was assessed by the Cronbach alpha test, while dimensionality was examined using exploratory factor analysis.</p><p><strong>Results: </strong>Data from 400 participants (mean age 18.8 ± 1.5 years; 52.2% women) comprising 47.0% with and 53.0% without TMDs were evaluated. Total-DASS and the 3 subscales showed acceptable to high internal consistencies for the WT and NT groups, with alphas of 0.78-0.94 and 0.66-0.92, respectively. Although 3 factors contributed to about half the variance for both groups, scalar and item discrepancies in the primary anxiety-stress factor existed.</p><p><strong>Conclusion: </strong>The DASS-21 has good reliability but may comprise only 2 dimensions, specifically anxiety-stress and depression, instead of the 3 originally asserted.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"452-460"},"PeriodicalIF":2.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10466954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of occlusal splint therapy on the masseter and temporalis muscles in female patients with myofascial pain syndrome: An ultrasonographic study.","authors":"Berk Bilgen, Enes Akpınar, Rabia Duman Tepe, Hülya Çakır Karabaş, Olcay Şakar","doi":"10.1080/08869634.2025.2490297","DOIUrl":"https://doi.org/10.1080/08869634.2025.2490297","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the impact of occlusal splint (OS) therapy on clinical parameters, masticatory muscle morphology and arterial blood flow using ultrasonography (USG) in female probable bruxist individuals with myofascial pain syndrome (MPS).</p><p><strong>Methods: </strong>24 female probable bruxist patients with MPS underwent OS therapy for three months. USG assessed masseter and temporalis muscle length, thickness (at rest and maximum clenching) and elastography. Doppler ultrasound measured facial, external carotid, temporal and maxillary artery blood flow. Clinical evaluations included maximum mouth opening (MMO), Jaw Functional Limitation Scale (JFLS) and Visual Analog Scale (VAS) scores. All measurements were conducted before and after treatment.</p><p><strong>Results: </strong>OS therapy significantly reduced muscle length, thickness and elastography, except for right masseter elastography. Temporal artery flow parameters showed a significant decrease. MMO increased, while JFLS and VAS scores decreased.</p><p><strong>Conclusion: </strong>OS therapy reduces muscle dimensions and stiffness while improving clinical outcomes, with limited impact on arterial blood flow.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"1-11"},"PeriodicalIF":2.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144013092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quality, reliability, and content on social media about temporomandibular joint disorders: A systematic review.","authors":"Vini Mehta, Sapna Negi, Snehal Rajendra Jagtap, Mansi Agrawal, Snehasish Tripathy, Ankita Mathur, Amit Reche","doi":"10.1080/08869634.2025.2482271","DOIUrl":"https://doi.org/10.1080/08869634.2025.2482271","url":null,"abstract":"<p><strong>Objective: </strong>This systematic review aims to assess the quality, reliability, and content of TMD-related social media posts across multiple platforms.</p><p><strong>Methods: </strong>A comprehensive search of three databases were conducted. TMD related content on social media sites were considered eligible. The extracted data was narratively synthesized.</p><p><strong>Results: </strong>Out of 254 studies, seven were included. YouTube was the most commonly assessed social media platform (n=5). Information created by amateurs encourages greater interaction than that of experts or news outlets. A majority videos and threads cover treatment choices. However, there is a noticeable absence of discussion on complications and prevention methods. Health professionals' videos scored better in quality and reliability than -professionals' videos.</p><p><strong>Conclusion: </strong>There is a need for creating evidence-based, accessible, and engaging content on TMD on social media and consideration of implementing rigorous information verification methods to ensure that high-quality, expert-validated content is prioritized in search results.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"1-11"},"PeriodicalIF":2.0,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144020685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of telerehabilitation-supported exercises in patients with temporomandibular disorders with probable sleep bruxism during the COVID-19 pandemic: A randomized controlled trial.","authors":"Ezgi Hatice Abaci, Aysenur Tuncer, Abidin Hakan Tuncer","doi":"10.1080/08869634.2025.2493365","DOIUrl":"https://doi.org/10.1080/08869634.2025.2493365","url":null,"abstract":"<p><strong>Objective: </strong>This study evaluated telerehabilitation-supported exercises' effects on pain, neck disability, anxiety, oral behaviors, and sleep quality in patients with Temporomandibular Disorders associated with probable sleep bruxism (TMDs-SB).</p><p><strong>Methods: </strong>During the COVID-19 pandemic (March 2021-May 2022), 40 patients aged 18-65 with TMDs-SB were randomized to a telerehabilitation (<i>n</i> = 20) or home exercise (<i>n</i> = 20) groups. Both received education and exercises; the telerehabilitation group supervised 30-minute weekly WhatsApp video sessions for eight weeks. Outcomes were assessed at baseline and eight weeks.</p><p><strong>Results: </strong>Both groups improved significantly in all outcomes from baseline to eight-week follow-up (<i>p</i> < .05). Telerehabilitation showed greater reductions in morning jaw pain (<i>p</i> = .012), neck disability (<i>p</i> = .032), trait anxiety (<i>p</i> = .028), and oral behaviors (<i>p</i> = .001) versus home exercises. Sleep quality improved similarly in both groups (<i>p</i> = .154).</p><p><strong>Conclusions: </strong>Telerehabilitation effectively reduced TMDs-SB symptoms, offering a promising alternative to unsupervised exercises during the pandemic. Given this unique context, conducting studies outside the pandemic's conditions would enhance generalizability and clarify telerehabilitation's potential. Further studies are needed to confirm its efficacy beyond pandemic conditions.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"1-12"},"PeriodicalIF":2.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144041584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vincent Fricton, Nathan Larkin, Linda Sangalli, Janey Prodoehl, William S Rayens, James Fricton
{"title":"Confidence in diagnosing and treating temporomandibular disorders among dental students and faculty following implementation of the revised standards 2-24k: A cross-sectional study.","authors":"Vincent Fricton, Nathan Larkin, Linda Sangalli, Janey Prodoehl, William S Rayens, James Fricton","doi":"10.1080/08869634.2025.2482265","DOIUrl":"https://doi.org/10.1080/08869634.2025.2482265","url":null,"abstract":"<p><strong>Objective: </strong>Following recognition of orofacial pain as specialty in 2020, US dental schools are now mandated to incorporate temporomandibular disorder (TMD) education into their predoctoral curricula. However, the perception of dental students regarding their TMD knowledge is unclear. This study assessed confidence in diagnosing and treating TMD among dental students at a predoctoral dental school where TMD instruction has been integrated across the dental curriculum.</p><p><strong>Methods: </strong>A 10-item REDCap-survey was distributed to all dental students and faculty, assessing self-perceived confidence in TMD (0-100, 100=\"Extremely confident\"). Between-group differences were analyzed with independent t-tests and within-group differences across academic years and grade-point average (GPA) with ANOVA.</p><p><strong>Results: </strong>Among the 145 participants (108 = dental students), overall confidence in TMD was 52.7 ± 25.8 (49.3 ± 24.5 among students, 63.5 ± 26.8 among faculty). All participants reported the highest confidence in distinguishing between TMD/dental pain (59.5 ± 23.9) and the least confidence in adjusting occlusal appliances (43.8 ± 32.4). Students felt less confident than faculty in differentiating between TMD/dental pain (<i>p</i> = .005), establishing TMD diagnoses (<i>p</i> = .003), explaining TMD to patients (<i>p</i> = .010), understanding necessity for treatment (<i>p</i> = .003), adjusting occlusal appliances (<i>p</i> < .0001), and communicating with other providers (<i>p</i> < .001). Fourth-year students exhibited significantly higher confidence in establishing TMD diagnoses (<i>p</i> = .023), adjusting appliances (<i>p</i> < .001), and communicating with other providers than students in other academic years (<i>p</i> = .033). Students with higher GPA were more confident in differentiating between TMD/dental pain than those with lower GPA (<i>p</i> = .015).</p><p><strong>Conclusion: </strong>TMD-perceived confidence can improve with training. The current TMD curricula may be lacking in specific areas, emphasizing the importance of structured TMD education within all dental curricula.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"1-14"},"PeriodicalIF":2.0,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Louis G Mercuri, Charles S Greene, Daniele Manfredini
{"title":"The temporomandibular joint disc: A complex fable about an elusive butterfly.","authors":"Louis G Mercuri, Charles S Greene, Daniele Manfredini","doi":"10.1080/08869634.2025.2477963","DOIUrl":"https://doi.org/10.1080/08869634.2025.2477963","url":null,"abstract":"<p><strong>Introduction: </strong>Discussions related to the diagnosis and management of temporomandibular joint (TMJ) disorders (TMDs) have always been interesting, and at times controversial, since they involve combinations of dental, medical, and surgical etiological theories and management strategies. Amongst the various recommendations that emerged over the years was that any dental and surgical procedures that are primarily focused on mandible repositioning and irreversible changes to dental occlusion should be avoided. This statement has important implications for appraising the validity of physiopathology concepts and treatment proposals centered around the evaluation of TMJ disc position, since they also generally lead to performing irreversible procedures.</p><p><strong>Methods: </strong>A review of the pertinent TMJ literature related to the articular disc position and its association with TMD symptoms was carried out by the authors.</p><p><strong>Results: </strong>For many practitioners, the position of the TMJ disc has been regarded as a primary cause of TMJ pain and dysfunction. For decades, incoordination between the TMJ disc, the condylar head and the articular eminence was indeed considered the main factor for the etiology of intracapsular TMD symptoms and consequently an important target for therapy. However, research has shown that synovitis is the more important variable in dealing with those conditions.</p><p><strong>Conclusion: </strong>In this commentary, the biological rationale to consider synovitis, rather than disc position, as the linchpin for clinical symptoms is presented in detail. Hopefully, this might contribute to putting the elusive butterfly characteristics of this topic finally to rest.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"1-8"},"PeriodicalIF":2.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea Frosolini, Simone Benedetti, Daniele Manfredini, Matteo Pollis, Paolo Gennaro, Guido Gabriele
{"title":"Evaluating the association of temporomandibular disorders with audiological symptoms through instrumental diagnostics: A systematic review.","authors":"Andrea Frosolini, Simone Benedetti, Daniele Manfredini, Matteo Pollis, Paolo Gennaro, Guido Gabriele","doi":"10.1080/08869634.2025.2485028","DOIUrl":"https://doi.org/10.1080/08869634.2025.2485028","url":null,"abstract":"<p><strong>Objective: </strong>Temporomandibular disorders (TMDs) have been historically linked to symptoms such as tinnitus, hearing loss, and vertigo. The aim of this systematic review is to investigate the association between TMDs and audiological symptoms.</p><p><strong>Methods: </strong>Adhering to the PRISMA guidelines, a comprehensive literature search in three databases was performed searching for studies utilizing imaging and audiometric assessments to diagnose TMDs and audiological symptoms. Of the 1153 studies retrived, a total number of 6 studies were included.</p><p><strong>Results: </strong>Although tinnitus was commonly reported among patients with TMDs, objective audiological deficits were not consistently confirmed. The majority of existing studies lack standardized diagnostic methods and the heterogeneity of methodologies and limited sample sizes restricted the feasibility of a meta-analysis.</p><p><strong>Conclusions: </strong>The lack of appropriate instrumental diagnostic tests makes it difficult to draw conclusions about the causal relationship between TMDs and audiological symptoms. Future trials are needed to clarify this clinical association.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"1-13"},"PeriodicalIF":2.0,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143789392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ovidiu Ionut Saracutu, Marco Ferrari, Matteo Pollis, Daniele Manfredini, Edoardo Ferrari Cagidiaco
{"title":"The outcome of prosthodontic treatments in individuals with bruxism and different restoration material. A scoping literature review.","authors":"Ovidiu Ionut Saracutu, Marco Ferrari, Matteo Pollis, Daniele Manfredini, Edoardo Ferrari Cagidiaco","doi":"10.1080/08869634.2025.2477964","DOIUrl":"https://doi.org/10.1080/08869634.2025.2477964","url":null,"abstract":"<p><strong>Objective: </strong>To review the clinical success of the various prosthodontic materials (e.g., lithium disilicate, zirconia, resin composite) in patients with different frequencies of bruxism.</p><p><strong>Methods: </strong>A systematic search in the most relevant databases to find any randomized clinical trial that assesses the outcome of prosthodontic restorations performed in subjects where an assessment of sleep bruxism (SB) and awake bruxism (AB) was Conducted.</p><p><strong>Results: </strong>No article present in the literature met the inclusion and exclusion criteria.</p><p><strong>Conclusion: </strong>The present systematic review unveils an important gap in the field of prosthodontics: no clinical trial in the literature has ever investigated the long-term success rate of different prosthodontic materials in patients with different frequencies of AB and SB.</p>","PeriodicalId":56318,"journal":{"name":"Cranio-The Journal of Craniomandibular & Sleep Practice","volume":" ","pages":"1-13"},"PeriodicalIF":2.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}