成人上呼吸道空气动力学特征与阻塞性睡眠呼吸暂停严重程度的关系。

IF 2 4区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Cranio-The Journal of Craniomandibular & Sleep Practice Pub Date : 2025-07-01 Epub Date: 2023-11-19 DOI:10.1080/08869634.2023.2278958

Xiaoya Wang, Lu Jia, Xin Xu, Jing Guo

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引用次数: 0

摘要

目的:探讨成人上呼吸道空气动力学特征与阻塞性睡眠呼吸暂停(OSA)严重程度的关系。方法:97例OSA患者行多导睡眠图和锥形束计算机断层扫描(CBCT)。基于CBCT图像和上气道计算流体动力学建模测量解剖和空气动力学特征。结果:在控制患者性别、年龄、体质指数(BMI)后，吸气时最大流速(in - vmax)对呼吸暂停低通气指数(AHI)变化的解释力增加最大。In-Vmax与最小轴向面积密切相关，两者的关系呈反比拟合曲线。结论:in - vmax与OSA严重程度相关度最高，可用于辅助识别OSA严重程度患者，并可作为评价OSA治疗效果的主要变量。In-Vmax与上气道最狭窄区域密切相关。

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The relationship between aerodynamic characteristics of the upper airway and severity of obstructive sleep apnea in adults.

Objective: To investigate the relationship between aerodynamic characteristics of the upper airway and severity of obstructive sleep apnea (OSA) in adults.

Methods: Ninety-seven adult OSA patients underwent polysomnography and cone beam computed tomography (CBCT). The anatomical and aerodynamic characteristics were measured based on CBCT images and computational fluid dynamics modelling of the upper airway.

Results: After controlling for patients' gender, age, and body mass index (BMI), the maximum velocity during inspiration (In-Vmax) led to the largest increase in the explanatory power of apnea-hypopnea index (AHI) variation. The In-Vmax was closely correlated with the minimum axial area, and their relationship was represented by an inversely proportional fitted curve.

Conclusions: The In-Vmax was the most relevant to OSA severity, and it could be used to assist in recognizing severe OSA patients and as a primary variable to evaluate treatment outcomes of OSA. The In-Vmax was closely related to the most constricted area of the upper airway.

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来源期刊

Cranio-The Journal of Craniomandibular & Sleep Practice DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

4.50

自引率

12.50%

发文量

审稿时长

>12 weeks

期刊介绍： CRANIO: The Journal of Craniomandibular & Sleep Practice is the oldest and largest journal in the world devoted to temporomandibular disorders, and now also includes articles on all aspects of sleep medicine. The Journal is multidisciplinary in its scope, with editorial board members from all areas of medicine and dentistry, including general dentists, oral surgeons, orthopaedists, radiologists, chiropractors, professors and behavioural scientists, physical therapists, acupuncturists, osteopathic and ear, nose and throat physicians. CRANIO publishes commendable works from outstanding researchers and clinicians in their respective fields. The multidisciplinary format allows individuals practicing with a TMD emphasis to stay abreast of related disciplines, as each issue presents multiple topics from overlapping areas of interest. CRANIO''s current readership (thousands) is comprised primarily of dentists; however, many physicians, physical therapists, chiropractors, osteopathic physicians and other related specialists subscribe and contribute to the Journal.