Revanth Kumar Salavadi, Jangam Sowmya, Baswa Mani Kumari, Kavitha P Kamath, Pradeep S Anand, Nambi Muni Roopesh Kumar, Pranavi Jadhav
{"title":"\"Comparison of the efficacy of Erich arch bars, IMF screws and SMART Lock Hybrid arch bars in the management of mandibular fractures- A Randomized clinical study\".","authors":"Revanth Kumar Salavadi, Jangam Sowmya, Baswa Mani Kumari, Kavitha P Kamath, Pradeep S Anand, Nambi Muni Roopesh Kumar, Pranavi Jadhav","doi":"10.1016/j.jormas.2025.102217","DOIUrl":"https://doi.org/10.1016/j.jormas.2025.102217","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to assess and compare the efficacy of Erich Arch Bar (EAB), Inter Maxillary Fixation (IMF) screws and SMART Lock Hybrid arch bar (HABs) in the treatment of mandibular fractures.</p><p><strong>Materials and methods: </strong>A prospective randomized clinical study was carried out in the Department of Dentistry at ESIC Hospital in Hyderabad from August 2021 to August 2023. The study comprised of three groups (EAB group (31), IMF screw group (33) and HABs group (29)).Primary outcome variable was occlusal stability. Secondary outcome variables were time taken to apply the device, glove perforation, oral hygiene assessment by Modified Turskey Gilmore Plaque index, Quality of life (QOL) assessment by General Oral Health Assessment Index (GOHAI), mucosal growth and dental injuries.</p><p><strong>Results: </strong>The average application time for EAB, IMF screws and HABs was 78 min, 15 min and 19 min respectively. No significant difference was noticed in occlusal stability at the end of 1 week and 4 weeks follow-up period. There was no statistically significant difference in instances of dental injury among the three groups. However, there were statistically significant differences (P < 0.05) in the time taken to apply, glove perforation, oral hygiene levels, mucosal overgrowth and total GOHAI score among the 3 groups.</p><p><strong>Conclusion: </strong>HABs and IMF screws may be recommended over EABfor MMF inmandibular dentate segment fracture management due to their advantages including quick application, enhanced occlusal stability, and QOL, all of which are required for a better functional outcome.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102217"},"PeriodicalIF":2.2,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142962599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Toward a standardized educational framework in burning mouth syndrome: Implications for clinical practice.","authors":"Takayuki Suga, Akira Toyofuku","doi":"10.1016/j.jormas.2025.102213","DOIUrl":"10.1016/j.jormas.2025.102213","url":null,"abstract":"","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102213"},"PeriodicalIF":2.2,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nizyara Costa da Silva, Débora Frota Colares, Luana Beatriz Ribeiro Lima, Hannah Gil de Farias Morais, Amanda Katarinny Goes Gonzaga, Maria Luiza Diniz de Sousa Lopes, Antônio de Lisboa Lopes Costa
{"title":"Clinical, radiographic, and histopathological characterization of Osteomyelitis of the Jaws: A 51-Year experience at an oral pathology service.","authors":"Nizyara Costa da Silva, Débora Frota Colares, Luana Beatriz Ribeiro Lima, Hannah Gil de Farias Morais, Amanda Katarinny Goes Gonzaga, Maria Luiza Diniz de Sousa Lopes, Antônio de Lisboa Lopes Costa","doi":"10.1016/j.jormas.2025.102222","DOIUrl":"10.1016/j.jormas.2025.102222","url":null,"abstract":"<p><strong>Introduction: </strong>Osteomyelitis is an inflammatory condition of the bone with a multifactorial etiology, including trauma and odontogenic infections. Despite being a common condition in clinical practice, limited research exists on the clinical and pathological profile of Osteomyelitis of the Jaws (OJ). This 51-year retrospective study aimed to describe the clinical, radiographic, and histopathological features of OJ diagnosed at a single oral pathology referral center.</p><p><strong>Material and methods: </strong>Clinical, radiographic, and histopathological data of cases diagnosed as OJ were collected and categorized using Zurich Classification System.</p><p><strong>Results: </strong>Among 17,991 cases diagnosed at the service, 75 (0.004 %) were identified as OJ. Patients were predominantly female (n = 67; 89.3 %), with a mean age of 42.68 years (±21.10) at diagnosis. OJ commonly presented as slow-growing, symptomatic lesions (n = 69; 92.0 %) with a predilection for the mandible. Secondary chronic osteomyelitis (SCO) was the most common subtype (n = 44; 84.0 %). Odontogenic infections were identified as the most common etiological factor associated with OJ (n = 41; 54.7 %). Radiographic analysis frequently revealed generalized, moderate bone loss, while histopathological examination often showed a discrete mononuclear inflammatory infiltrate (n = 29; 38.7 %). Bacterial colonies were observed in 26 cases (34.7 %) and were significantly associated with SCO (p = 0.04).</p><p><strong>Conclusion: </strong>The findings indicate that OJ is a rare condition in oral pathology centers, predominantly affecting white females in their fifth decade at life, with a predilection for the mandible. Dental infections were the primary causative factor. SCO is the most common OJ subtype in cases requiring surgical management.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102222"},"PeriodicalIF":2.2,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Expression and correlation of the long noncoding RNA PDIA3P and FAK/TGF-β pathway in oral submucous fibrosis rats.","authors":"Fan di Zhu, Yu Xuan Li, Ru Qian Guo, Yun Xu","doi":"10.1016/j.jormas.2025.102214","DOIUrl":"https://doi.org/10.1016/j.jormas.2025.102214","url":null,"abstract":"<p><p>Oral Submucous Fibrosis constitutes a severe condition affecting the lining of the mouth, which carries a risk of developing into oral squamous cell carcinoma, and seriously threaten individuals' lives. Currently, no specific treatment has been utilized to prevent OSF. The detailed mechanism of OSF is still elusive, and this study aims to clarify the mechanism of OSF.</p><p><strong>Methods: </strong>This study was conducted to elucidate the molecular mechanisms of the long noncoding RNA PDIA3P (lncRNA PDIA3P) and FAK/TGF-β pathway in OSF. The OSF mice model was established by injecting with injected with 1000 mg/L arecoline solution, then the blood samples and oral submucosal tissues were collected from all groups of rats for further testing. HE staining, immunofluorescence, Western blot, and qRT-PCR were then used to elucidate the molecular mechanisms of the molecular mechanisms of the lncRNA PDIA3P and FAK/TGF-β pathway in OSF.</p><p><strong>Results: </strong>The results showed that upregulation of the FAK/TGF-β signaling pathway can accelerate OSF process, while the downregulation of the FAK/TGF-β signaling pathway can prevent the OSF process. Similarly, enhanced activity of the lncRNA PDIA3P is implicated with OSF process, while reducing its level can served as a preventative method against the OSF development.</p><p><strong>Conclusion: </strong>Upregulating the lncRNA PDIA3P and FAK/TGF-β pathway can accelerate the process of OSF.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102214"},"PeriodicalIF":2.2,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdul Karim Sharif, Hedayatullah Ehsan, Abdul Wahab Abri, Sayed Wahabuddin Mirzad, Khujasta Amin
{"title":"Surgical management of a large plunging ranula: A case report and review of diagnostic challenges.","authors":"Abdul Karim Sharif, Hedayatullah Ehsan, Abdul Wahab Abri, Sayed Wahabuddin Mirzad, Khujasta Amin","doi":"10.1016/j.jormas.2025.102219","DOIUrl":"10.1016/j.jormas.2025.102219","url":null,"abstract":"<p><strong>Introduction: </strong>Ranulas are mucous cysts that arise from the sublingual gland due to ductal obstruction or trauma. Plunging ranulas, a rare variant, extend into the neck and often present diagnostic challenges. Definitive surgical management is necessary to prevent recurrence and ensure successful outcomes.</p><p><strong>Case presentation: </strong>A 20-year-old female presented with a slowly enlarging, painless mass in the floor of her mouth extending into the submandibular region and anterior neck. The mass had progressively increased in size over five years, affecting her appearance and mastication. MRI confirmed a large plunging ranula. The patient underwent complete surgical excision of the cyst and the sublingual gland under general anesthesia. She recovered well, with no immediate postoperative complications. Follow-up at 12 months showed no recurrence, and the patient reported full resolution of symptoms.</p><p><strong>Conclusion: </strong>This case highlights the importance of early recognition and accurate diagnosis of plunging ranulas to guide appropriate surgical intervention. Complete excision of the sublingual gland remains the treatment of choice for preventing recurrence. In line with similar cases in the literature, this approach resulted in a successful outcome with no evidence of recurrence during follow-up. The findings underscore the clinical significance of individualized treatment strategies based on the extent of anatomical involvement.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102219"},"PeriodicalIF":2.2,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of BSSRO on disc-condyle relationship of the temporomandibular joint in skeletal Class III malocclusion patients.","authors":"Ming-Yang Song, Xin Lv, Zheng Zhang, Yu-Xin Wang, Cheng-Wan Xia, Xu-Dong Yang","doi":"10.1016/j.jormas.2025.102215","DOIUrl":"10.1016/j.jormas.2025.102215","url":null,"abstract":"<p><strong>Purpose: </strong>To analyze dynamic and static changes in the disc-condyle relationship in patients with skeletal Class III malocclusion after orthognathic surgery.</p><p><strong>Methods: </strong>The surgical group comprised 30 patients with skeletal Class III malocclusion, and the magnetic resonance imaging and mandibular movement data were obtained at T0 (preoperatively), T1 (3 months postoperatively), and T2 (at the end of orthodontic treatment). The control group included 20 patients with normal occlusion, and the mandibular movement data were recorded.</p><p><strong>Results: </strong>The maximum mouth opening at T1 decreased compared with that at T0 and recovered close to the preoperative level at T2. The marginal movement of the mandible at T1 decreased compared with that at T0 (P > 0.05), among which the movement distances of the condyles during mouth opening and closing decreased significantly compared with those at T0(P < 0.05). Following postoperative orthodontics in patients with skeletal Class III malocclusion, RET-L was significantly lower than that in the control group(P < 0.05).Regarding the temporomandibular joint of ADDwR, the CPL at T1 decreased significantly compared with that at T0(P < 0.05). At T2, the LPM, LLM, and CPL increased significantly compared with those at T1(P < 0.05), and the LPM and LLM levels at T2 exceeded those at T0 significantly (P < 0.05).</p><p><strong>Conclusions: </strong>In the short term, after orthognathic surgery, the marginal movement of the mandible showed a certain degree of decline; however, in the long term, it recovered or even exceeded the preoperative level. Orthognathic surgery results in a particularly significant improvement in the functional movement of the ADDwR joint. In addition, it improves TMD in patients with skeletal Class III malocclusion and has a positive effect on improving the position of the joint disc position.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102215"},"PeriodicalIF":2.2,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mapping the research landscape on temporomandibular disorders and orthodontics treatment: A bibliometric analysis.","authors":"Lulu Pan, Xianyu Mao, Xi Ding, Pengcheng Ye","doi":"10.1016/j.jormas.2025.102212","DOIUrl":"10.1016/j.jormas.2025.102212","url":null,"abstract":"<p><strong>Background: </strong>Temporomandibular disorders (TMD) and orthodontic treatment are significant areas within dental and maxillofacial research. However, comprehensive bibliometric analyses highlighting global trends and collaboration networks are lacking.</p><p><strong>Objective(s): </strong>This study aims to systematically map the publication landscape, identify prevailing research trends, highlight influential authors and institutions, and illuminate emerging topics in TMD and orthodontic research.</p><p><strong>Methods: </strong>Publications concerning TMD and orthodontic treatment from 2000 to 2024 were retrieved from the Web of Science Core Collection. A bibliometric analysis was conducted using VOSviewer, CiteSpace, and R to evaluate co-authorship networks, institutional collaborations, and keyword co-occurrence patterns.</p><p><strong>Results: </strong>A total of 871 publications were identified, with an average annual growth rate of 4.4 %. Contributions came from 47 countries and involved 3,463 authors, with the USA and Japan leading in citations. Notable institutions included Kyung Hee University and Baylor University. Key journals included the American Journal of Orthodontics and Dentofacial Orthopedics and the Journal of Oral and Maxillofacial Surgery. Frequently occurring keywords were \"temporomandibular-joint,\" \"orthognathic surgery,\" and \"orthodontic treatment,\" indicating essential research foci. Emerging trends highlighted advancements in surgical techniques and technological innovations in orthodontics.</p><p><strong>Conclusion: </strong>This bibliometric analysis offers valuable insights into global research trends and hotspots in TMD and orthodontic treatment, emphasizing the collaborative nature of the field and illuminating emerging areas for future investigation.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102212"},"PeriodicalIF":2.2,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noémie Vanden Haute, Emma Bach, Pierre Bouletreau, Alice Prevost, Pierre Corre, Louis Brochet, Nicolas Graillon, Andrea Varazzani
{"title":"An updated overview of orthognathic surgery practices in France.","authors":"Noémie Vanden Haute, Emma Bach, Pierre Bouletreau, Alice Prevost, Pierre Corre, Louis Brochet, Nicolas Graillon, Andrea Varazzani","doi":"10.1016/j.jormas.2024.102210","DOIUrl":"10.1016/j.jormas.2024.102210","url":null,"abstract":"<p><strong>Introduction: </strong>Orthognathic surgery is a fundamental component of a maxillofacial surgeon's practice. In France, 510 specialists actively practice oral and maxillofacial surgery. In OMFs, despite the existence of evidence-based recommendation that address diagnosis, treatment planning, and operating methods, each surgeon/institution has developed an individual approach towards clinical management. This study comprehensively overviews the current practices of French orthognathic surgeons.</p><p><strong>Methods: </strong>A questionnaire was electronically sent to 500 oral and maxillofacial surgeons in France, some of whom practiced orthognathic surgery and some of whom did not. The answers were anonymous.</p><p><strong>Results: </strong>We obtained 52 responses. With consensus on 12 of the practical, economic, and peri-operative questions. We didn't find difference on any topics where the surgeon has his residence or the age of the surgeon. Management and correction of occlusal disorders were the primary indications for osteotomy. Of all responders, 42 % were in private practice. Both virtual and conventional planning methods were used, with no clear preference for either method. During bimaxillary surgery, 76 % of surgeons initially osteotomised and stabilised the maxilla; 69 % used an intermediate splint. ERAS protocols are not used.</p><p><strong>Conclusion: </strong>This study is an update and it provides new information compared a 2002 report on orthognathic surgery in France. It highlights a consensus on conventional planning but no significant influence from academic centers, age, or experience on surgical practices. New technologies and ERAS protocols are underused despite their benefits for safer surgeries. There is a lack of standardized procedures, leading to varied practices despite a national teaching program. More data and practitioner involvement are needed to develop French and European guidelines.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102210"},"PeriodicalIF":2.2,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Leonard Knoedler, Cosima C Hoch, Thomas Schaschinger, Tobias Niederegger, Samuel Knoedler, Christian Festbaum, Iman Ghanad, Rainer Pooth, Barbara Wollenberg, Steffen Koerdt, Christian Doll, Max Heiland, Andreas Kehrer
{"title":"Objective and automated facial palsy grading and outcome assessment after facial palsy reanimation surgery - A prospective observational study.","authors":"Leonard Knoedler, Cosima C Hoch, Thomas Schaschinger, Tobias Niederegger, Samuel Knoedler, Christian Festbaum, Iman Ghanad, Rainer Pooth, Barbara Wollenberg, Steffen Koerdt, Christian Doll, Max Heiland, Andreas Kehrer","doi":"10.1016/j.jormas.2024.102211","DOIUrl":"10.1016/j.jormas.2024.102211","url":null,"abstract":"<p><strong>Background: </strong>Facial palsy (FP) is a widespread condition affecting over 3 million people annually, with a complex etiology requiring tailored, multidisciplinary management. Despite advancements, there remains a lack of reliable, automated tools for objective pre- and postoperative assessment, limiting progress in treatment optimization. This study introduces the AI Research Metrics Model (CAARISMA ® ARMM) to evaluate FP severity and outcomes following microsurgical gracilis muscle transfer.</p><p><strong>Methods: </strong>We analyzed pre- and postoperative images of 20 FP patients using CAARISMA ® ARMM, which identifies 17 facial landmarks and evaluates 1,030 parameters. CAARISMA ® ARMM calculates three indices: Facial Youthfulness Index (FYI), Facial Aesthetic Index (FAI), and Skin Quality Index (SQI). All surgical procedures were performed by the senior author. Statistical analysis compared preoperative and postoperative scores using independent t-tests and Wilcoxon-Mann-Whitney tests, with significance set at p < 0.05.</p><p><strong>Results: </strong>Significant improvements were observed in the FAI scores post-surgery (p < 0.001). In contrast, FYI and SQI scores did not show significant postoperative changes (p = 0.39 and p = 0.60, respectively). Significant gender differences emerged: females showed increased FYI scores postoperatively, while males exhibited a decline (p = 0.0065). Age-related variations were also significant, with younger patients showing improved SQI and older patients experiencing declines (p = 0.040).</p><p><strong>Conclusion: </strong>The CAARISMA ® ARMM effectively captures aesthetic improvements post-reanimation. Gender and age significantly influence outcomes, underscoring the key role of personalized and adaptable assessment tools. Future studies should integrate dynamic assessments and validate the CAARISMA ® ARMM across additional patient populations. CAARISMA ® ARMM holds promise as a standardized tool in FP outcome evaluation.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102211"},"PeriodicalIF":2.2,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142900876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sakhr Alshwayyat, Hanan M Qasem, Lina Khasawneh, Mustafa Alshwayyat, Mesk Alkhatib, Tala Abdulsalam Alshwayyat, Hamza Al Salieti, Ramez M Odat
{"title":"Mucoepidermoid carcinoma: Enhancing diagnostic accuracy and treatment strategy through machine learning models and web-based prognostic tool.","authors":"Sakhr Alshwayyat, Hanan M Qasem, Lina Khasawneh, Mustafa Alshwayyat, Mesk Alkhatib, Tala Abdulsalam Alshwayyat, Hamza Al Salieti, Ramez M Odat","doi":"10.1016/j.jormas.2024.102209","DOIUrl":"10.1016/j.jormas.2024.102209","url":null,"abstract":"<p><strong>Background: </strong>Oral cancer, particularly mucoepidermoid carcinoma (MEC), presents diagnostic challenges due to its histological diversity and rarity. This study aimed to develop machine learning (ML) models to predict survival outcomes for MEC patients and pioneer a clinically accessible prognostic tool.</p><p><strong>Methods: </strong>Using the SEER database (2000-2020), we constructed predictive models with five ML algorithms: Random Forest Classifier (RFC), Gradient Boosting Classifier (GBC), Logistic Regression (LR), K-Nearest Neighbors (KNN), and Multilayer Perceptron (MLP). Predictive variables were identified via Cox regression, and Kaplan-Meier analysis assessed survival trends. Model performance was validated through the area under the curve (AUC) of receiver operating characteristic (ROC) curves.</p><p><strong>Results: </strong>This study included 1314 patients diagnosed with MEC of the oral cavity. The RFC demonstrated the highest predictive accuracy (AUC = 0.55), followed by the GBC and RFC (AUC = 0.53). The most affected primary site was the hard palate, followed by the retromolar and cheek mucosa. Survival rates varied with the treatment modality, with the highest rates observed in patients undergoing surgery alone. ML models have identified age, sex, and metastasis as significant prognostic factors influencing survival outcomes, underscoring the complexity and heterogeneity of MEC.</p><p><strong>Conclusions: </strong>This study highlights ML's potential to enhance survival predictions and personalize treatment for MEC patients. We developed the first web-based prognostic tool, providing a novel, accessible solution for improving clinical decision-making in MEC.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102209"},"PeriodicalIF":2.2,"publicationDate":"2024-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142900873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}