Journal of Stomatology Oral and Maxillofacial Surgery最新文献

{"title":"Oral stent for peri-implant soft tissue management on jaw reconstruction: A simple, fast, and predictable technique.","authors":"Chloé Mense, Emmanuelle Lasserre, Yassine Bouabid, Benjamin Pomes","doi":"10.1016/j.jormas.2025.102325","DOIUrl":"10.1016/j.jormas.2025.102325","url":null,"abstract":"<p><p>Maxillofacial defects from tumor ablative surgery often bring about masticatory dysfunction. Reconstruction with vascularized flaps and oral rehabilitation are often challenging. Whenever possible, dental implants can improve patients' quality of life and comfort but the shallowness or absence of the oral vestibule, the flaps' position, volume and mobility, the nature of surrounding tissues do not always allow a fabrication of prostheses in satisfactory conditions. The use of an oral stent was proposed to control, guide healing and position tissue around implants according to prosthetic needs. This article introduces a technic to fabricate a custom oral stent which is interesting because simple, fast, predictable and inexpensive.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102325"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143782129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transconjunctival Lower Blepharoplasty with Orbital Fat Repositioning versus Fat Grafting for Tear Trough Deformity: A Prospective, Comparative and Randomized Study.","authors":"Jingni Li, Ting Xie, Xintong Jiang, Minli Yang, Beilei Wang, Hengxin Liu","doi":"10.1016/j.jormas.2025.102320","DOIUrl":"https://doi.org/10.1016/j.jormas.2025.102320","url":null,"abstract":"<p><strong>Background: </strong>Fat prolapse and tear trough deformity, indicative of lower eyelid aging, are increasingly prevalent in younger patients. Transconjunctival lower blepharoplasty (TCLB) is a suitable treatment for this demographic; however, traditional techniques have limitations that affect their simplicity and effectiveness.</p><p><strong>Objective: </strong>We conducted a prospective, randomized controlled trial to systematically compare the modified TCLB technique with traditional TCLB in two groups, with the aim of evaluating its therapeutic efficacy through direct methodological comparison.</p><p><strong>Method: </strong>This study, conducted from August 2020 to August 2022, included 40 patients with lower eyelid fat prolapse and tear trough deformity, randomly assigned to either the experimental or control group. The experimental group underwent a modified TCLB technique, while the control group received traditional TCLB combined with orbital fat release. Postoperative outcomes were evaluated by comparing baseline data, surgical duration, changes in the vertical distance from the lowest point of the tear trough to the pupil, Barton tear trough classification, and the Global Aesthetic Improvement Scale(GAIS) between the two groups.</p><p><strong>Result: </strong>Preoperative baseline data showed no significant differences between the two groups. However, the experimental group had a significantly shorter surgical duration. Post-treatment comparisons revealed superior maintenance of surgical outcomes in the experimental group compared to the control group.</p><p><strong>Conclusion: </strong>This prospective, comparative, and randomized study demonstrates the favorable therapeutic effects of the modified TCLB technique.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102320"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143782130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of recombinant human epidermal growth factor in oral and maxillofacial trauma and its impact on healing time.","authors":"Xuming Wang, Xiaoli Ji","doi":"10.1016/j.jormas.2025.102326","DOIUrl":"https://doi.org/10.1016/j.jormas.2025.102326","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate the role of recombinant human epidermal growth factor (rhEGF) in promoting the healing of oral and maxillofacial (OMF) trauma, analyze its specific impact on healing time, and explore the biological mechanisms of rhEGF in facilitating wound recovery.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 135 patients with OMF trauma treated at our hospital from May 2023 to May 2024. Patients were divided into an observation group (72 cases) receiving rhEGF treatment and a control group (63 cases) receiving conventional therapy. Clinical efficacy, inflammatory responses, perioperative indicators, and other outcomes were compared between the two groups.</p><p><strong>Results: </strong>The observation group demonstrated a higher treatment efficacy rate (94.46%) compared to the control group (77.78%) (χ² = 16.151, P < 0.001). In the perioperative period, the observation group exhibited shorter healing time (t = 6.038, P < 0.001), reduced incision edema duration (t = 12.330, P < 0.001), and lower post-treatment VAS scores (t = 10.400, P < 0.001), though surgical duration was slightly longer (t = -24.145, P < 0.001). Inflammatory marker analysis revealed that EGF levels were higher (t = -13.969, P < 0.001), while IL-6 (t = 10.458, P < 0.001) and CRP levels (t = 14.092, P < 0.001) were lower in the observation group than in the control group. Scar hyperplasia occurred in only 2 cases in the observation group compared to 13 cases in the control group (χ² = 10.848, P < 0.001).</p><p><strong>Conclusion: </strong>rhEGF promotes wound healing in OMF trauma, accelerating recovery, shortening healing time, reducing inflammatory responses, and minimizing scar hyperplasia.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102326"},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143782128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep learning-based multimodal CT/MRI image fusion and segmentation strategies for surgical planning of oral and maxillofacial tumors: A pilot study.","authors":"Bin-Zhang Wu, Lei-Hao Hu, Si-Fan Cao, Ji Tan, Nian-Zha Danzeng, Jing-Fan Fan, Wen-Bo Zhang, Xin Peng","doi":"10.1016/j.jormas.2025.102324","DOIUrl":"10.1016/j.jormas.2025.102324","url":null,"abstract":"<p><strong>Purpose: </strong>This pilot study aims to evaluate the feasibility and accuracy of deep learning-based multimodal computed tomography/magnetic resonance imaging (CT/MRI) fusion and segmentation strategies for the surgical planning of oral and maxillofacial tumors.</p><p><strong>Materials and methods: </strong>This study enrolled 30 oral and maxillofacial tumor patients visiting our department between 2016 and 2022. All patients underwent enhanced CT and MRI scanning of the oral and maxillofacial region. Furthermore, three fusion models (Elastix, ANTs, and NiftyReg) and three segmentation models (nnU-Net, 3D UX-Net, and U-Net) were combined to generate nine hybrid deep learning models that were trained. The performance of each model was evaluated via the Fusion Index (FI), Dice similarity coefficient (Dice), 95th-percentile Hausdorff distance (HD95), mean surface distance (MSD), precision, and recall analysis.</p><p><strong>Results: </strong>All three image fusion models (Elastix, ANTs, and NiftyReg) demonstrated satisfactory accuracy, with Elastix exhibiting the best performance. Among the tested segmentation models, the highest degree of accuracy for segmenting the maxilla and mandible was achieved by combining NiftyReg and nnU-Net. Furthermore, the highest overall accuracy of the nine hybrid models was observed with the Elastix and nnU-Net combination, which yielded a Dice coefficient of 0.89 for tumor segmentation.</p><p><strong>Conclusion: </strong>In this study, deep learning models capable of automatic multimodal CT/MRI image fusion and segmentation of oral and maxillofacial tumors were successfully trained with a high degree of accuracy. The results demonstrated the feasibility of using deep learning-based image fusion and segmentation to establish a basis for virtual surgical planning.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102324"},"PeriodicalIF":2.2,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143774825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dispersed bacterial cellulose (DBC) alone graft material and adding DBC or the boric acid-absorbed DBC to xenograft increases the new bone formation during rabbit maxillary sinus augmentation- a pilot study.","authors":"Songül Cömert Kiliç, Murat Özdal, Nihat Kiliç, Onur Ceylan, Gönül Koç","doi":"10.1016/j.jormas.2025.102321","DOIUrl":"10.1016/j.jormas.2025.102321","url":null,"abstract":"<p><p>This study aimed to evaluate and compare the effects of bone grafting materials, including xenograft alone, DBC alone, xenograft + DBC, xenograft + boric acid, and xenograft + boric acid-absorbed DBC, on the newly formed bone, the immune reactivity score of osteoprotegerin (OPG) and Receptor Activator Nuclear Kappa-B Ligand (RANKL) and the OPG/RANKL ratio by histological, histomorphometric and immunohistochemical analysis in rabbit maxillary sinus augmentation (MSA) model. Fourteen maxillary sinuses of New Zealand albino rabbits were augmented. Five groups were formed: xenograft alone (group1), dispersed bacterial cellulose (DBC) alone (group2), xenograft + DBC (group3), xenograft + boric acid (group4), xenograft +boric acid-absorbed DBC (group5). Eight weeks later, the species were examined. SEM, XRD, and FTIR analyses were carried out for DBC and boric acid-absorbed DBC. Inter-group comparisons were carried out by using the Kruskal-Wallis test for the immune reactivity score of OPG and RANKL and the independent sample t-test for OPG/RANKL ratio. The highest newly formed bone was observed in groups 3 and 5, and the lowest was in group 1. The percentages of newly formed bone area from highest to lowest occurred at 43.3 %, 38.3 %, 33.3 %, 30 %, and 19.5 % in groups 5, 3, 4, 2, and 1, respectively. Increased expression of OPG and RANKL was observed around newly formed bone areas in all groups. The immune reactivity score of OPG and RANKL expression was highest in group 5 and lowest in group 1, with no significant difference between the groups. The OPG/RANKL ratio was 1 in all groups, except the ratio was > 1 in only group 5, with no significant difference between the groups. The surface of DBC showed a well-organized, irregular, and interconnected porous structure. DBC found a biocompatible material. Boric acid-absorbed DBC produced a more remarkable and enlarged pore structure than DBC alone. The findings of the present pilot study indicated that DBC alone can be used as a scaffold and it seems an innovative bone graft material to filling bone defect areas that it caused enhanced bone regeneration during MSA. Moreover, adding DBC or boric acid-absorbed DBC to xenograft increased newly formed bone significantly.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102321"},"PeriodicalIF":2.2,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective study of morphological and functional analysis of mandibular reconstructions using iliac and fibular flaps.","authors":"Drissa Diarra, Jialiang Chen, Hao Lin, Bang Zeng, Qiwen Man, Weiwei Deng, Bushabu Fidele Nyimi, Tianfu Wu, Bing Liu","doi":"10.1016/j.jormas.2025.102322","DOIUrl":"10.1016/j.jormas.2025.102322","url":null,"abstract":"<p><strong>Objective: </strong>This retrospective study aims to evaluate and compare the morphological and functional characteristics of mandibular reconstructions performed using iliac and fibular flaps to determine their respective effectiveness and identify the technique that offers the best patient outcomes.</p><p><strong>Methods: </strong>Medical and imaging data were analysed from pre- and post-operative scans of 121 patients (84 with iliac flaps and 37 with fibular flaps). Mandibular reconstructions were assessed by comparing morphometric parameters (distances and angles) and symmetry between the affected and unaffected sides using Mimics software. The quality of life of patients was assessed using a modified version of the University of Washington Quality of Life Questionnaire (UW-QOL), version 4, which evaluates functional and psychosocial outcomes in head and neck cancer treatment RESULTS: The results show that the iliac group demonstrates significantly superior performance for distances D2 and D3 and for the CA angle on the unaffected side. In contrast, the fibular group shows no significant advantage in these parameters. Regarding symmetry, the iliac group achieves better results for distance D3, whereas the fibular group excels in angular measurements. Additionally, the iliac group maintains better stability for angle B. Regarding bone dimensions, the iliac flap better preserves alveolar base height (ABH) and width (ABW), providing more consistent and favorable outcomes than the fibular flap.No overall difference was observed between the two groups regarding quality of life (assessed using the UW-QOL questionnaire). However, specific variations were noted: the fibular group scores higher for pain, activity, and recreation, while the iliac group achieves better results in appearance and speech.</p><p><strong>Conclusion: </strong>The iliac flaps are the preferred option for mandibular reconstruction, offering superior morphometric stability, better preservation of bone dimensions, and more robust structural consistency than fibular flaps. Although both techniques yield comparable overall quality-of-life results, iliac flaps demonstrate more pronounced clinical benefits, leading to optimal postoperative outcomes.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102322"},"PeriodicalIF":2.2,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomechanical Evaluation of Zygomatic-Orbital-Maxillary Complex Fractures Following Internal Fixation.","authors":"Yan Li, Wei-Hao Zhou, Yu-Ran Ding, Ping He, Chen-Cheng Mo, Xiang-Dong Qi","doi":"10.1016/j.jormas.2025.102323","DOIUrl":"https://doi.org/10.1016/j.jormas.2025.102323","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study is to develop effective treatment strategies for zygomatic-orbital-maxillary complex (ZOMC) fractures using finite element analysis (FEA) and investigate the mechanical properties and stress distribution of different internal fixators.</p><p><strong>Methods: </strong>A three-dimensional (3D) model was created from CT images of a patient with a unilateral ZOMC fracture, and the preinjury craniofacial structure was reconstructed. A cylindrical impactor was used to simulate facial impact. Biomechanical analysis was performed to assess the stability of internal fixation of the fracture lines at the frontal process of the zygomatic bone (FPZB), inferior orbital rim (IOR), and upper and lower parts of the zygomaticomaxillary suture (ZMS). The impact of different fixation methods on the anterior-inferior wall of the maxillary sinus (AIWMS) was also assessed in this study. A 120 N load was used to simulate physiological muscle force, and the maximum von Mises stress and maximum displacement for the fracture ends were assessed.</p><p><strong>Results: </strong>The stress distribution on the impact model was similar to that on the patient's fracture lines, with all internal fixation devices experiencing maximum stress below the yield stress. The model exhibiting the largest displacement of the zygomatic body, IOR, and FPZB had not undergone internal fixation of the FPZB. The greatest maximum displacement value was recorded for the maxilla, at the non-fixed lower ZMS. The maximum displacement value was lower for 2 fixators placed at the AIWMS than for a single fixator placed at the fracture midline.</p><p><strong>Conclusions: </strong>The placement of 2 internal fixators along the zygomaticomaxillary (NMB) and nasomaxillary buttresses (NMB) provides greater stability than the placement of a single device does. Moreover, stabilizing the fracture lines in the FPZB is essential, as doing so reduces the extent of displacement of free fracture ends by counteracting the masseter muscle force.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102323"},"PeriodicalIF":2.2,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microvascular reconstruction of complicated nasal defects using the novel temporal artery-based preauricular composite free flap: A report of two cases, critical aspects and a review of the literature.","authors":"Christian Soemmer, Lars Bonitz, Akos Bicsak, Stefan Haßfeld, Evangelos N Vitkos","doi":"10.1016/j.jormas.2025.102319","DOIUrl":"10.1016/j.jormas.2025.102319","url":null,"abstract":"<p><strong>Introduction: </strong>The nose's anatomy, structure, and positioning play a pivotal role in defining facial aesthetics. As the most common site for non-melanoma skin cancer, restoring the nose's natural appearance after ablative surgery poses significant challenges in the ever-evolving field of reconstructive surgery. By adhering to the principles of reconstructive surgery and the facial subunit division theory, numerous techniques have been developed, with local and regional flaps remaining key tools for surgeons.</p><p><strong>Observation: </strong>The advent of free tissue transplantation has transformed facial reconstructive surgery by enabling complex restorations that preserve local anatomy while minimizing donor and recipient site morbidity. This study reports two cases of complex nasal defects involving skin and cartilage. A novel temporal artery-based preauricular composite free flap was used for reconstruction. While one patient achieved successful reconstruction, the other experienced delayed flap necrosis.</p><p><strong>Discussion: </strong>These cases underscore the potential and surgical utility of \"like-to-like\" free flap facial reconstruction. The use of composite free flaps expands the surgeon's ability to address complex nasal defects while striving for functional and aesthetic outcomes. This report seeks to highlight this approach's capabilities and contribute to the limited literature available.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102319"},"PeriodicalIF":2.2,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vascularized iliac crest free flap in maxillofacial reconstruction: Pearls and pitfalls from 437 clinical application.","authors":"Hao Lin, Bang Zeng, Linzhou Zhang, Xuepeng Xiong, Zhe Shao, Linlin Bu, Yanfang Sun, Sirui Ma, Chunyue Ma, Zhengjun Shang, Jun Jia, Tianfu Wu, Bing Liu","doi":"10.1016/j.jormas.2025.102318","DOIUrl":"10.1016/j.jormas.2025.102318","url":null,"abstract":"<p><strong>Objective: </strong>The vascularized iliac crest free (VICF) flap has been a cornerstone in maxillofacial reconstruction for decades. This study aims to provide a framework for guiding and managing maxillofacial reconstruction using the VICF flap, highlighting key techniques and potential pitfalls to optimize outcomes and reduce practice variability.</p><p><strong>Methods: </strong>A retrospective review was conducted on 437 patients (439 flaps) who underwent maxillofacial reconstruction with VICF flaps. The study summarized current practices, challenges, and strategies for successful flap application. Data were collected from electronic medical records and postoperative follow-ups.</p><p><strong>Results: </strong>The overall success rate of VICF flap transplantation was 98.4 %. Of the 439 VICF flaps, 37 were myo-osteocutaneous, 47 were myo-osseous, and 355 were osseous. Computer-assisted techniques (CATs) were used in 64.5 % (282/437) of cases. The average University of Washington Quality of Life score was 83.38, and the Harris Hip Score averaged 93.34. The incidence of serious complications was low, with 6 % (17/285) of patients reporting moderate-to-severe pain and 8.4 % (24/285) experiencing incisional hernia. Additionally, 11.9 % (34/285) of patients have completed implant-supported restoration.</p><p><strong>Conclusion: </strong>VICF flaps offer significant morphological advantages and ample bone quantity for reconstruction; however, they are associated with some postoperative complications. With advancements in CAT and the application of chimeric perforator flaps, VICF can be successfully used to address most maxillofacial defects, including those caused by benign and malignant tumors in the neck, especially in cases with good vascular supply.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102318"},"PeriodicalIF":2.2,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment approaches in cases of mandibular osteoradionecrosis: A systematic meta-analysis.","authors":"Nida Geçkil","doi":"10.1016/j.jormas.2025.102316","DOIUrl":"10.1016/j.jormas.2025.102316","url":null,"abstract":"<p><strong>Background: </strong>Osteoradionecrosis (ORN) refers to necrotic bone that remains unhealed for a minimum of 3 months following radiotherapy in an irradiated region. The aim of this systematic meta-analysis was to evaluate the efficacy of hyperbaric oxygen therapy and surgery alone or in combination in the treatment of patients with ORN.</p><p><strong>Methods: </strong>A systematic review and analysis of literature were performed to ascertain the role of surgery and HBO in the treatment of ORN. In May 2024 we updated the searches of the Cochrane Central Register of Controlled Trials (CENTRAL), (The Cochrane Library, Issue 1), MEDLINE, EMBASE, DORCTIHM and reference lists of articles.</p><p><strong>Results: </strong>Among patients who underwent both HBO and surgery, the success rate of the treatment was 69 % (95 % Confidence Interval [CI]: 0.47-0.85, df = 9). Patients who solely received HBO had a success rate of 38 % (CI: 0.20-0.61, df = 4), while those who only had surgery had a success rate of 36 % (CI: 0.19-0.58, df = 3). The statistical analysis showed no significant difference in the results between patients who received only hyperbaric oxygen therapy or surgical treatment (z=0.139, p=0.889). The analysis indicated significant disparities in treatment success rates among patients receiving a combination of HBO and surgery compared to those treated solely with HBO or surgery alone (z = 2.428, p = 0.015 for HBO vs HBO+surgery, z = 2.655, p = 0.008 for surgery vs HBO+surgery).</p><p><strong>Conclusion: </strong>The findings of this study indicate that the combination of HBO and surgery is a more effective approach for managing ORN, with better results observed when treatments are combined rather than used individually.</p>","PeriodicalId":56038,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":" ","pages":"102316"},"PeriodicalIF":2.2,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}