Risk Management and Healthcare Policy最新文献

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Development and Validation of a Risk Prediction Model for Interdialytic Hyperkalemia in Patients Undergoing Maintenance Hemodialysis. 维持性血液透析患者透析间期高钾血症风险预测模型的建立与验证。
IF 2 4区 医学
Risk Management and Healthcare Policy Pub Date : 2025-11-20 eCollection Date: 2025-01-01 DOI: 10.2147/RMHP.S552431
Pan Wang, Jun-Nan Xiao, Yan-Yu Liu, Long Xiao, Jie-Li Chen, Yu Wang, Li-Hua Yang, Xiu-Li Feng
{"title":"Development and Validation of a Risk Prediction Model for Interdialytic Hyperkalemia in Patients Undergoing Maintenance Hemodialysis.","authors":"Pan Wang, Jun-Nan Xiao, Yan-Yu Liu, Long Xiao, Jie-Li Chen, Yu Wang, Li-Hua Yang, Xiu-Li Feng","doi":"10.2147/RMHP.S552431","DOIUrl":"10.2147/RMHP.S552431","url":null,"abstract":"<p><strong>Background: </strong>Interdialytic hyperkalemia is linked to a heightened risk of adverse clinical outcomes among patients undergoing maintenance hemodialysis (MHD). This study aimed to develop and validate a nomogram to assess the risk of interdialytic hyperkalemia in this patient population.</p><p><strong>Methods: </strong>A total of 312 patients undergoing MHD were retrospectively enrolled from two hemodialysis centers between January 2024 and December 2024. The group was randomly divided into a training set and a validation set in a 7:3 ratio. Least absolute shrinkage and selection operator regression was applied to identify independent predictors of hyperkalemia, which were subsequently incorporated into a multivariate logistic regression model. Model performance was assessed using receiver operating characteristic curve analysis, area under the curve (AUC), calibration plots, and decision curve analysis (DCA) to assess both discrimination and clinical utility.</p><p><strong>Results: </strong>The overall incidence of interdialytic hyperkalemia was 28.2%. The final nomogram included seven predictors: dietary potassium intake, dietary phosphorus intake, serum albumin concentration, pre-dialysis blood glucose level, interdialytic weight gain rate, time interval since the last dialysis session, and a history of hyperkalemia within the preceding three months. The model demonstrated strong discriminatory ability with an AUC of 0.905 (95% Confidence Interval (CI): 0.883-0.931) in the training set and 0.782 (95% CI: 0.756-0.819) in the validation set. Calibration plots indicated good agreement between predicted and observed outcomes. DCA confirmed the clinical applicability of the model by demonstrating a net benefit across a range of threshold probabilities.</p><p><strong>Conclusion: </strong>A nomogram-based risk prediction model for interdialytic hyperkalemia in patients undergoing MHD was developed and externally validated. The model demonstrated robust predictive performance and may assist clinicians in early identification of patients who are at high-risk, thereby supporting timely interventions.</p>","PeriodicalId":56009,"journal":{"name":"Risk Management and Healthcare Policy","volume":"18 ","pages":"3713-3724"},"PeriodicalIF":2.0,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12642932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145607613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Pre-Hospital and in-Hospital Optimization on the Management of Intravenous Thrombolysis in Hyperacute Ischemic Stroke: A Scoping Review. 院前和院内优化对超急性缺血性脑卒中静脉溶栓管理的影响:一项范围综述
IF 2 4区 医学
Risk Management and Healthcare Policy Pub Date : 2025-11-19 eCollection Date: 2025-01-01 DOI: 10.2147/RMHP.S553410
Talitha Elvina Ayu Kharisma, Lisda Amalia, Lika Apriani, Fathul Huda, Aih Cahyani
{"title":"Impact of Pre-Hospital and in-Hospital Optimization on the Management of Intravenous Thrombolysis in Hyperacute Ischemic Stroke: A Scoping Review.","authors":"Talitha Elvina Ayu Kharisma, Lisda Amalia, Lika Apriani, Fathul Huda, Aih Cahyani","doi":"10.2147/RMHP.S553410","DOIUrl":"10.2147/RMHP.S553410","url":null,"abstract":"<p><strong>Introduction: </strong>Stroke is the second leading cause of death worldwide and ranks third as a cause of disability. The American Heart Association/American Stroke Association (AHA/ASA) recommends that treatment begin within three hours of onset with intravenous thrombolysis therapy. This scoping review aimed to identify the factors that influence the delay in intravenous thrombolysis (IVT) management in patients with ischemic stroke.</p><p><strong>Methods: </strong>We searched relevant studies in PubMed, ScienceDirect, and EBSCO and this review includes studies on ischemic stroke patients that analyze the factors contributing to delays in intravenous thrombolysis therapy, and it demonstrates that such delays are present in the management of IVT.</p><p><strong>Results: </strong>A total of 48 studies were included in this study. Among pre-hospital factors, the most frequently reported contributors to delays in IVT for acute ischemic stroke (AIS) patients were the use of Emergency Medical Services (EMS) (12 studies), mode of hospital presentation (12 studies), comorbidities (6 studies), symptom recognition (5 studies), and timing of event (5 studies), with several studies reporting statistically significant associations (p<0.05). Emergency department use shortened hospital admission time by an average of 30 minutes, p<0.05Regarding in-hospital delay factors, the main contributors to delays included long scan times (5 studies), low NIHSS scores (5 studies), and limited implementation of stroke programs (5 studies). Other in-hospital delay variables included delayed activation of stroke codes (3 studies), inefficiency of human resources (3 studies), suboptimal triage processes (2 studies), diagnostic process (1 study), and logistics (1 study).</p><p><strong>Conclusion: </strong>Delayed thrombolysis in ischemic stroke patients is caused by various factors, both pre-hospital and in-hospital. Community education and telemedicine can reduce delays by 30%. Collaboration between the community, stroke units, medical personnel, and the government through comprehensive programs is key in accelerating stroke treatment and improving patient clinical outcomes.</p>","PeriodicalId":56009,"journal":{"name":"Risk Management and Healthcare Policy","volume":"18 ","pages":"3689-3712"},"PeriodicalIF":2.0,"publicationDate":"2025-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12640776/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145607636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pattern of Pharmaceutical Poisoning in the Perak Population with Special Reference to the Age and Poisoning Mode Impact. 霹雳州人口药物中毒的模式,特别参考年龄和中毒方式的影响。
IF 2 4区 医学
Risk Management and Healthcare Policy Pub Date : 2025-11-18 eCollection Date: 2025-01-01 DOI: 10.2147/RMHP.S413695
Vesara Ardhe Gatera, Nur Najihah Izzati Mat Rani, Muhammad Firdaus Bin Ismail, Halilol Rahman Mohamed Khan, Nor Safwan Hadi Nor Afendi, Sulastri Samsudin, Ahmad Shalihin Mohd Samin, Noor Afiza Abdul Rani, Nur Azzalia Kamaruzaman
{"title":"Pattern of Pharmaceutical Poisoning in the Perak Population with Special Reference to the Age and Poisoning Mode Impact.","authors":"Vesara Ardhe Gatera, Nur Najihah Izzati Mat Rani, Muhammad Firdaus Bin Ismail, Halilol Rahman Mohamed Khan, Nor Safwan Hadi Nor Afendi, Sulastri Samsudin, Ahmad Shalihin Mohd Samin, Noor Afiza Abdul Rani, Nur Azzalia Kamaruzaman","doi":"10.2147/RMHP.S413695","DOIUrl":"10.2147/RMHP.S413695","url":null,"abstract":"<p><strong>Introduction: </strong> Exposure to pharmaceutical poisoning affects people of all ages around the globe, and this is a serious emergency and a major problem. The unsafe medication disposal, such as keeping it at home until it expires, throwing it away in household garbage, giving it to friends/relatives, and flushing it down the toilet, has the consequences of this accidental, homicidal, or suicidal pharmaceutical poisoning toward international communities that range from short-term illness to long-term complications. However, the impact of pharmaceutical poisoning on the Malaysian population is a regular and frequent practice of disposal methods for pharmaceutical waste, and the awareness of pharmaceutical waste can have an adverse impact.</p><p><strong>Purpose: </strong>This study aimed to investigate the exposure to and association between pharmaceutical poisoning and intentional and accidental factors in the population from Perak, 2019 to 2021.</p><p><strong>Patients and methods: </strong>This retrospective study evaluated reports from 348 patients with pharmaceutical poisoning in Perak, submitted to the National Poison Center (NPC) from 2019 to 2021. Initially, patient characteristics and clinical presentations were determined for pharmaceutical poisoning exposure, and their association with intentional and unintentional factors was analyzed.</p><p><strong>Results: </strong>This study found that the working-age group (48.28%) was the most represented age group. Psychiatric (23.0%) was the most frequent cause of poisoning. Quetiapine (2.9%) and calamine lotion (2.3%) were marked as the most common causes. Female sex (<i>p</i> < 0.001), working age (<i>p</i> < 0.001), and psychiatric agents (<i>p</i> < 0.001) were significantly associated with intentional poisoning, whereas male sex (<i>p</i> < 0.001), young age (<i>p</i> < 0.001), and topical agents (<i>p</i> < 0.001) were significantly associated with accidental poisoning.</p><p><strong>Conclusion: </strong>The exposure to pharmaceutical poisoning was associated with age, sex, psychiatric agents, and topical agents.</p>","PeriodicalId":56009,"journal":{"name":"Risk Management and Healthcare Policy","volume":"18 ","pages":"3665-3674"},"PeriodicalIF":2.0,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12640136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145589771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physical Exercise, Sports Spectating, and Subjective Life Expectancy in Older Chinese Adults: A Chain Mediation Analysis. 体育锻炼、体育观赛与中国老年人主观预期寿命:一个连锁中介分析。
IF 2 4区 医学
Risk Management and Healthcare Policy Pub Date : 2025-11-18 eCollection Date: 2025-01-01 DOI: 10.2147/RMHP.S565048
Longyin Chen, Jiru Guo, Xiya Han
{"title":"Physical Exercise, Sports Spectating, and Subjective Life Expectancy in Older Chinese Adults: A Chain Mediation Analysis.","authors":"Longyin Chen, Jiru Guo, Xiya Han","doi":"10.2147/RMHP.S565048","DOIUrl":"10.2147/RMHP.S565048","url":null,"abstract":"<p><strong>Background: </strong>Participation in sports can influence subjective life expectancy (SLE) among older Chinese adults, yet differences between direct physical exercise and indirect engagement through spectating are not well understood. This study distinguishes the effects of physical exercise and sports spectating-further differentiating online from offline viewing-on older adults' SLE, and examines the mediating roles of social integration and health status.</p><p><strong>Methods: </strong>A cross-sectional survey of 693 Chinese adults aged 60 and above was analyzed using mediation models.</p><p><strong>Results: </strong>Physical exercise was positively associated with SLE both directly (effect = 0.042, 95% CI [0.002, 0.081]) and indirectly through enhanced social integration and improved health (effect = 0.016, 95% CI [0.016, 0.038]). Offline sports viewing also produced indirect benefits via social interaction and health improvement, whereas online spectating influenced SLE mainly through health gains (effect = 0.013, 95% CI [0.004, 0.024]) with minimal impact on social integration (effect = 0.001, 95% CI [-0.005, 0.006]).</p><p><strong>Conclusion: </strong>This study demonstrates that direct and indirect forms of sports participation differentially shape older adults' SLE, with offline engagement offering greater benefits through social pathways. These findings have implications for aging policy, suggesting that interventions promoting physically active and socially interactive sports engagement may support more positive life expectancy perceptions in later life.</p>","PeriodicalId":56009,"journal":{"name":"Risk Management and Healthcare Policy","volume":"18 ","pages":"3675-3688"},"PeriodicalIF":2.0,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12640137/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145589752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physicians' Overwork Impacts Patient Satisfaction via Physician-Nurse Collaboration and Patients' Medical Risk Perception in China. 中国医师过度工作通过医护协作影响患者满意度和患者医疗风险感知。
IF 2 4区 医学
Risk Management and Healthcare Policy Pub Date : 2025-11-15 eCollection Date: 2025-01-01 DOI: 10.2147/RMHP.S537903
Kairu Zhou, Yuwen Xin, Min Li, Li Chen
{"title":"Physicians' Overwork Impacts Patient Satisfaction via Physician-Nurse Collaboration and Patients' Medical Risk Perception in China.","authors":"Kairu Zhou, Yuwen Xin, Min Li, Li Chen","doi":"10.2147/RMHP.S537903","DOIUrl":"10.2147/RMHP.S537903","url":null,"abstract":"<p><strong>Background and objective: </strong>To enhance healthcare service quality and foster harmonious doctor-patient relationships, it is necessary to explore the impact of physicians' overwork on patient satisfaction, with the mediating roles of physician-nurse collaboration and patients' medical risk perception in these relationships.</p><p><strong>Methods: </strong>Using a stratified random sampling method, questionnaire surveys were conducted from June to September 2023 among 90 physicians and 550 inpatients in 13 Grade A tertiary public hospitals across five provinces in China. This survey collected data on physicians' overwork, physician-nurse collaboration, patient's medical risk perception, and patient satisfaction. The data were analyzed using the PROCESS macro (Model 6) in SPSS 23 to examine the chain mediation model.</p><p><strong>Results: </strong>A total of 81 physicians and 512 inpatients were included. Physicians' overwork had a significant negative effect on patient satisfaction (<i>β</i> = -0.426, <i>p</i> < 0.001). Physician-nurse collaboration (<i>β</i> = 0.463, <i>p</i> < 0.001) and patients' medical risk perception (<i>β</i> = -0.260, <i>p</i> < 0.001) acted as partial mediators, accounting for 24.41% and 5.87% of the total effect, respectively. Furthermore, physicians' overwork indirectly affected patient satisfaction through a chain mediation pathway involving physician-nurse collaboration followed by patients' medical risk perception (<i>β</i> = -0.014, <i>p</i> < 0.001), accounting for 3.29% of the total effect.</p><p><strong>Conclusion: </strong>Physicians' overwork demonstrates a significant negative predictive effect on patient satisfaction, encompassing both direct and indirect effects mediated by physician-nurse collaboration and patients' medical risk perception. To improve healthcare quality and satisfaction, governments should address physicians' overwork and patient risk perception. Future research could explore physician-patient trust as a mediator or analyze how different dimensions of risk perception influence chain-mediated pathways.</p>","PeriodicalId":56009,"journal":{"name":"Risk Management and Healthcare Policy","volume":"18 ","pages":"3633-3645"},"PeriodicalIF":2.0,"publicationDate":"2025-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12630002/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145589713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Navigating Ethical and Legal Tensions in Mandatory Reporting of Intimate Partner Violence: Insights from Norwegian Assault Centers. 在亲密伴侣暴力的强制报告中导航道德和法律紧张:来自挪威攻击中心的见解。
IF 2 4区 医学
Risk Management and Healthcare Policy Pub Date : 2025-11-15 eCollection Date: 2025-01-01 DOI: 10.2147/RMHP.S541005
Anita Dyb Linge, Kjartan Leer-Salvesen, Solveig Karin Bø Vatnar
{"title":"Navigating Ethical and Legal Tensions in Mandatory Reporting of Intimate Partner Violence: Insights from Norwegian Assault Centers.","authors":"Anita Dyb Linge, Kjartan Leer-Salvesen, Solveig Karin Bø Vatnar","doi":"10.2147/RMHP.S541005","DOIUrl":"10.2147/RMHP.S541005","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to examine how health-care professionals in assault centers in Norway navigate biomedical ethical principles, health-care legislation, and the mandatory reporting law when working with victims of intimate partner violence (IPV). The study was guided by the following research questions: How do health-care professionals in assault centers apply the law for mandatory reporting of IPV (MR-IPV)? How do they navigate various factors when they consider applying the MR-IPV law?.</p><p><strong>Methods: </strong>This qualitative, explorative study is built on 12 individual, semi-structured interviews with nurses and medical doctors working at assault centers. The data were analyzed using Braun and Clarke's reflexive thematic analysis, with themes developed based on biomedical ethical principles, including relational autonomy.</p><p><strong>Results: </strong>Two main themes were found. First, MR-IPV was perceived as subsequent but parallel to emergency medical treatment. Some participants used risk assessment tools, and they all emphasized the importance of making patients safe following medical treatment. However, only a few acknowledged that their duty to respect the MR-IPV law was a factor in prioritizing patient safety. Second, ethical principles and health-care legislation were recognized more than the MR-IPV law, which created dilemmas for nurses and medical doctors. These actors faced challenges in navigating patients' autonomy and beneficence in relation to the MR-IPV legislation. Conflicts between patient autonomy and beneficence can lead to paternalistic behavior, which creates ethical dilemmas.</p><p><strong>Conclusion: </strong>The findings show tensions between medical practices and legal and ethical standards, which contributed to hesitation in reporting severe IPV cases to the police. Health-care professionals prioritized therapeutic relationships and patient confidentiality, sometimes at the expense of their responsibilities concerning the MR-IPV law. Addressing these challenges requires enhancing legal literacy and fostering a cultural shift in health care to align professional autonomy with legal requirements and institutional responsibilities.</p>","PeriodicalId":56009,"journal":{"name":"Risk Management and Healthcare Policy","volume":"18 ","pages":"3647-3663"},"PeriodicalIF":2.0,"publicationDate":"2025-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12628776/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145566241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cost-Effectiveness of First-Line Zuberitamab-CHOP versus Rituximab-CHOP Regimens in Untreated CD20+ Diffuse Large B-Cell Lymphoma in China. 在中国治疗CD20+弥漫性大b细胞淋巴瘤的一线Zuberitamab-CHOP与Rituximab-CHOP方案的成本-效果比较
IF 2 4区 医学
Risk Management and Healthcare Policy Pub Date : 2025-11-14 eCollection Date: 2025-01-01 DOI: 10.2147/RMHP.S553720
Lihong Gao, Haomin Zhu, Jia Wang, Yingtao Lin, Baolong Ding, Yuyang Sun, Tiantian Tao, Xin Li
{"title":"Cost-Effectiveness of First-Line Zuberitamab-CHOP versus Rituximab-CHOP Regimens in Untreated CD20+ Diffuse Large B-Cell Lymphoma in China.","authors":"Lihong Gao, Haomin Zhu, Jia Wang, Yingtao Lin, Baolong Ding, Yuyang Sun, Tiantian Tao, Xin Li","doi":"10.2147/RMHP.S553720","DOIUrl":"10.2147/RMHP.S553720","url":null,"abstract":"<p><strong>Purpose: </strong>To conduct a cost-effectiveness analysis comparing zuberitamab combined with CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone; Hi-CHOP) versus rituximab combined with CHOP (R-CHOP) as first-line therapy for previously untreated CD20-positive diffuse large B-cell lymphoma (DLBCL) patients in China.</p><p><strong>Patients and methods: </strong>A partitioned survival model (PSM) was developed to conduct a cost-effectiveness analysis of Hi-CHOP versus R-CHOP regimens in newly diagnosed CD20-positive DLBCL patients. The study utilized a 20-year time frame. Evaluated outcomes included overall survival (OS), quality-adjusted life-years (QALYs), total treatment costs, and incremental cost-effectiveness ratios (ICERs). The willingness-to-pay (WTP) threshold was defined as $40,334.05 per QALY, equivalent to triple China's 2024 per capita GDP.</p><p><strong>Results: </strong>The base-case analysis indicated that Hi-CHOP provided an additional 1.49 life-years and 1.57 QALYs compared to R-CHOP. The total treatment cost of Hi-CHOP was $238,164.77 higher than that of R-CHOP over 20 years, resulting in ICERs of $151,373.19 per QALY and $160,273.99 per life-year. One-way sensitivity analysis (OSA) identified progression-free survival (PFS) utility as the most significant parameter impacting model outcomes. Probabilistic sensitivity analysis (PSA) demonstrated that almost all simulated outcomes surpassed the WTP threshold. The cost-effectiveness acceptability curve (CEAC) demonstrated R-CHOP's superior cost-effectiveness probability relative to Hi-CHOP across a WTP range from $0 to $150,000.</p><p><strong>Conclusion: </strong>Given that Hi-CHOP is not cost-effective at conventional WTP thresholds, a substantial price reduction or unnecessary procedures, and optimizing clinical workflows for Hi-CHOP would be necessary to make it an economically viable first-line option for DLBCL compared to R-CHOP.</p>","PeriodicalId":56009,"journal":{"name":"Risk Management and Healthcare Policy","volume":"18 ","pages":"3621-3632"},"PeriodicalIF":2.0,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12625742/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145558485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Daily Improvement in APACHE II Score (APACHE/m) and Outcomes in ICU Trauma Patients. ICU创伤患者APACHE II评分(APACHE/m)和预后的每日改善
IF 2 4区 医学
Risk Management and Healthcare Policy Pub Date : 2025-11-13 eCollection Date: 2025-01-01 DOI: 10.2147/RMHP.S561237
Pao-Jen Kuo, Sheng-En Chou, Hang-Tsung Liu, Ching-Hua Tsai, Ching-Hua Hsieh
{"title":"Daily Improvement in APACHE II Score (APACHE/m) and Outcomes in ICU Trauma Patients.","authors":"Pao-Jen Kuo, Sheng-En Chou, Hang-Tsung Liu, Ching-Hua Tsai, Ching-Hua Hsieh","doi":"10.2147/RMHP.S561237","DOIUrl":"10.2147/RMHP.S561237","url":null,"abstract":"<p><strong>Background: </strong>The Acute Physiology and Chronic Health Evaluation II (APACHE II) is a widely used intensive care unit (ICU) severity score; however, it provides only an admission snapshot. Therefore, we introduced a novel metric, APACHE/m (average daily decrease in APACHE II score during ICU stay), to examine whether faster physiological improvement was correlated with better outcomes in ICU trauma patients.</p><p><strong>Methods: </strong>This retrospective cohort study was conducted at a level I trauma center. Participants comprised 1784 adult trauma patients admitted to the ICU (2016-2023) who survived ICU discharge were included in this study. The APACHE II scores at ICU admission and discharge were recorded. APACHE/m was calculated as the decrease in APACHE II divided by the length of stay in the ICU. We analyzed the ability of APACHE/m to predict post-ICU in-hospital mortality and compared outcomes between the high and low APACHE/m groups. Propensity score matching (1:1) was used to adjust for initial injury severity and comorbidities.</p><p><strong>Results: </strong>Hospital mortality after ICU discharge was 2.3% (41/1784). APACHE/m alone showed poor discrimination for mortality (AUC = 0.57). In the unmatched cohort, mortality was 2.6% in high APACHE/m patients (>1.03 points/day) vs 2.0% in low APACHE/m patients (≤1.03), P = 0.523. After matching (199 pairs), high APACHE/m patients had longer hospital stays (median, 14 vs 12 days, P = 0.005) and higher mortality (3.5% vs 0%, P = 0.022) than matched low APACHE/m patients.</p><p><strong>Conclusion: </strong>A rapid APACHE II score decline (high APACHE/m) did not predict improved survival in ICU trauma patients. Paradoxically, the patients with the fastest APACHE II improvements had similar or worse late outcomes, likely because they were initially more critically ill. Thus, initial severity remains an important predictor of outcomes than the ICU recovery rate.</p>","PeriodicalId":56009,"journal":{"name":"Risk Management and Healthcare Policy","volume":"18 ","pages":"3609-3619"},"PeriodicalIF":2.0,"publicationDate":"2025-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12622357/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145551911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Best Evidence for Preventing Urinary Tract Infections and Optimizing Care in Adults with Indwelling Urinary Catheters. 预防尿路感染和优化成人留置导尿管护理的最佳证据。
IF 2 4区 医学
Risk Management and Healthcare Policy Pub Date : 2025-11-11 eCollection Date: 2025-01-01 DOI: 10.2147/RMHP.S557548
Jiayan Tang, Yanhong Fan, Jiayun Lu, Yongfang Zhang
{"title":"Best Evidence for Preventing Urinary Tract Infections and Optimizing Care in Adults with Indwelling Urinary Catheters.","authors":"Jiayan Tang, Yanhong Fan, Jiayun Lu, Yongfang Zhang","doi":"10.2147/RMHP.S557548","DOIUrl":"10.2147/RMHP.S557548","url":null,"abstract":"<p><strong>Background: </strong>Catheter-associated urinary tract infection (CAUTI) is the most frequent hospital-acquired infection and remains a major challenge for nursing quality and infection control. Existing studies are fragmented, and high-quality evidence syntheses are lacking.</p><p><strong>Objective: </strong>This study aimed to systematically search for relevant evidence on the prevention and care of catheter-associated urinary tract infections. The evidence was evaluated and integrated to provide reference for clinical practice.</p><p><strong>Design: </strong>This study was conducted as a systematic evidence summary, following a systematic review methodology to identify, appraise, and synthesize best available evidence on the prevention and care of catheter-associated urinary tract infections.</p><p><strong>Methods: </strong>Identify the evidence-based questions, based on the \"6S\" evidence pyramid model, evidence related to the prevention and care of urinary tract infections in patients with indwelling urinary catheters were systematically searched from relevant databases and relevant websites for clinical decisions, guidelines, evidence summaries, systematic reviews and expert consensuses. The study was initiated in December 2024, and the search period covered from database inception to January 2025. Three researchers who had completed their professional training and assessment at the Evidence-based Nursing Center conducted literature screening, quality evaluation, and evidence synthesis. The study population was global, not restricted to a specific region.</p><p><strong>Results: </strong>Fourteen studies were included: two clinical decision-making articles, eight guideline articles, two systematic review articles and two expert consensus articles. A total of 32 pieces of evidence were formed in five aspects: pre-catheterization criteria, catheterization techniques and requirements, daily care and maintenance of urinary catheters, catheter removal, and diagnosis and treatment of CAUTI.</p><p><strong>Conclusion: </strong>This study summarizes the best available evidence on the prevention and care of urinary tract infections in patients with indwelling urinary catheters. The findings provide an evidence base for clinical nursing practice, enhance nurses' awareness of CAUTI prevention and care, and support the development of evidence-informed protocols for clinical settings.</p><p><strong>Trial registration: </strong>This study was registered at the Center for Evidence-Based Nursing of Fudan University (registration number ES20257362).</p>","PeriodicalId":56009,"journal":{"name":"Risk Management and Healthcare Policy","volume":"18 ","pages":"3593-3608"},"PeriodicalIF":2.0,"publicationDate":"2025-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12619583/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145544161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Artificial Intelligence-Assisted Closed-Loop Mobile Nursing Information Management on Nursing Quality Indicators and Work Efficiency. 人工智能辅助闭环移动护理信息管理对护理质量指标及工作效率的影响
IF 2 4区 医学
Risk Management and Healthcare Policy Pub Date : 2025-11-05 eCollection Date: 2025-01-01 DOI: 10.2147/RMHP.S548275
Xing Yuan, Lihong Zhu, Kaili Jiang, Jinyan Chen
{"title":"Impact of Artificial Intelligence-Assisted Closed-Loop Mobile Nursing Information Management on Nursing Quality Indicators and Work Efficiency.","authors":"Xing Yuan, Lihong Zhu, Kaili Jiang, Jinyan Chen","doi":"10.2147/RMHP.S548275","DOIUrl":"10.2147/RMHP.S548275","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to construct and evaluate an AI-assisted mobile nursing information closed-loop management model.</p><p><strong>Methods: </strong>This study adopted a prospective before-after control design to compare nursing indicators before and after model implementation, conducted in the Pediatric Surgery Department of Anqing Municipal Hospital Affiliated with China Pharmaceutical University, where an information management system was implemented. A statistical analysis was conducted on the quality control data of 3891 cases (from 438 hospitalized patients) before model implementation (March to May 2024) and 3697 cases (from 417 patients) after implementation (July to September 2024) to evaluate its effectiveness. Existing quality control indicators were reviewed, and new/updated metrics generated from the implementation of new nursing closed-loop management measures were evaluated. AI-driven tools were leveraged to enhance the early warning capabilities of mobile nursing information systems through data acquisition, collection, and interpretation, and establishing a closed-loop management model for mobile nursing information.</p><p><strong>Results: </strong>Following the model implementation, significant improvements were observed in all evaluated indicators. The bedside settlement completion rate rose from 66.16% to 83.3% (χ²=61.63, *p*<0.001), and the critical value reception rate increased from 51.72% to 93.55% (χ²=21.78, *p*<0.001). The nursing plan and workflow completion rates improved to 98.17% and 94.89% (both *p*<0.001), respectively. Nursing work efficiency surged from 3.03 to 25 tasks per hour, and overall patient satisfaction increased from 83.3% to 97.65%, confirming the model's effectiveness in enhancing nursing quality and patient experience.</p><p><strong>Conclusion: </strong>The AI-assisted mobile nursing information closed-loop management model presented here was found to enhance nursing work efficiency, improve patient experience, and optimize workflow processes, contributing to a more effective and structured nursing management system.</p>","PeriodicalId":56009,"journal":{"name":"Risk Management and Healthcare Policy","volume":"18 ","pages":"3581-3591"},"PeriodicalIF":2.0,"publicationDate":"2025-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12596850/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145490492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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