Risk Management and Healthcare Policy最新文献

{"title":"Assessing the Severity of ODT and Factors Determinants of Late Arrival in Young Patients with Acute Ischemic Stroke.","authors":"Letao Zhu, Yanfeng Li, Qingshi Zhao, Changyu Li, Zongbi Wu, Youli Jiang","doi":"10.2147/RMHP.S476106","DOIUrl":"10.2147/RMHP.S476106","url":null,"abstract":"<p><strong>Background: </strong>Acute ischemic stroke (AIS) is increasingly affecting younger populations, necessitating prompt thrombolytic therapy within a narrow therapeutic window. Pre-hospital delays are prevalent, particularly in China, yet targeted research on the youth population remains scarce.</p><p><strong>Methods: </strong>In this retrospective cohort study, data from AIS patients aged 18-50 admitted to Longhua District People's Hospital, Shenzhen from December 2021 to December 2023 were analyzed using XGBoost and Random Forest machine learning algorithms, coupled with SHAP visualization, to identify factors contributing to pre-hospital delays.</p><p><strong>Results: </strong>Among 1954 AIS patients, 528 young patients were analyzed. The median time to hospital arrival was 8.34 hours, with 82.0% experiencing delays. Analysis of different age subgroups showed that young patients aged 36-50 years old had a higher delay rate than patients under 36 years old. Machine learning algorithms identified stroke awareness, age, TOAST classification, ambulance arrival, dysarthria, mRS on admission, dizziness, wake-up stroke, etc. as important determinants of delay.</p><p><strong>Conclusion: </strong>This study highlights the necessity of machine learning in identifying delay risk factors in young stroke patients. Enhanced public education, particularly regarding stroke symptoms and the use of emergency services, is crucial for reducing pre-hospital delays and improving patient outcomes.</p>","PeriodicalId":56009,"journal":{"name":"Risk Management and Healthcare Policy","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11536978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142585203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric Properties of Chinese Version of the Barriers to Error Disclosure Assessment (C-BEDA) Tool.","authors":"Rong-Rong Huang, Yu-Sheng Xie, Gui-Ru Chen, Zhao-Qing Liu","doi":"10.2147/RMHP.S477701","DOIUrl":"10.2147/RMHP.S477701","url":null,"abstract":"<p><strong>Aim: </strong>The Barriers to Error Disclosure Assessment (BEDA) tool is used to measure barriers to the disclosure of medical errors by healthcare professionals. This study aimed to evaluate the psychometric properties of the Chinese version of the BEDA (C-BEDA).</p><p><strong>Background: </strong>The culture of disclosure and transparency in response to medical errors has been recommended in recent years. However, there are no relevant assessment tools for measuring barriers to disclosing medical errors in China.</p><p><strong>Methods: </strong>The C-BEDA tool underwent translation, back translation, cross-cultural adaptation in a pilot study. It was tested with 1254 healthcare professionals in Guizhou and Sichuan Provinces, China. The content validity index (CVI) was used to evaluate the content validity of the C-BEDA, and exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were used to evaluate its structural validity. The Cronbach's α coefficient and test-retest reliability were evaluated to determine its reliability.</p><p><strong>Results: </strong>Three factors were extracted by EFA that explained 65.892% of the total variance of the C-BEDA tool. CFA showed a good fit for a three-factor structure with acceptable values: goodness-of-fit index=0.939; adjusted goodness-of-fit index=0.911; incremental fit index=0.967; comparative fit index=0.967; partial least squares path modeling for confirmatory factor analysis=0.735; and root mean square error of approximation=0.058. The item-level content validity index ranged from 0.86 to 1.00, and the average scale-level content validity index was 0.98. The Cronbach's α coefficient (0.909) and test-retest reliability (0.86) were acceptable.</p><p><strong>Conclusion: </strong>The C-BEDA toolis a valid and reliable tool for assessing the extent of barriers to error disclosure among Chinese healthcare professionals.</p>","PeriodicalId":56009,"journal":{"name":"Risk Management and Healthcare Policy","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11536977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142585207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Saudi Radiology Technologists' Perception of Occupational Hazards from a Personal and Social Lens.","authors":"Khalid M Alshamrani, Dana A Alzahrani, Yara S Alghamdi, Lama M Aljohani, Ziyad F Al Nufaiei","doi":"10.2147/RMHP.S492974","DOIUrl":"10.2147/RMHP.S492974","url":null,"abstract":"<p><strong>Background: </strong>Occupational hazards among healthcare workers (HCWs) present serious risks, from infectious diseases to physical and chemical dangers, along with psychological stress, all of which threaten their health and safety. This study aims to identify the unique challenges and hazards encountered by radiology technologists in in Saudi Arabia by assessing the key factors contributing to these risks.</p><p><strong>Methods: </strong>A descriptive questionnaire study was conducted in January-February 2023, targeting 75 radiology technologists at King Abdulaziz Medical City (KAMC), Jeddah, with participants recruited via non-probability convenience sampling and invited to complete a widely recognized questionnaire previously used among radiographers. Descriptive statistics were calculated, and the Kruskal-Wallis <i>H</i>-test was conducted to examine the relationships between demographic factors and different aspects of occupational hazards.</p><p><strong>Results: </strong>Of the 75 technologists contacted, 63 responded, resulting in an 84% participation rate. Workload, work shifts, and patient-related factors are major contributors to occupational hazards, surpassing technologist-specific and organizational elements. Additionally, 68.3% cited rigid leadership and unequal treatment as aggravating factors, while insufficient staffing, inadequate protective devices, and patient interaction were also significant concerns. Over 60% identified bending, lifting heavy patients, prolonged radiation exposure, and frequent walking as major hazard sources.</p><p><strong>Conclusion: </strong>Key occupational hazards factors facing radiology technologists include high workloads, work shifts, and patient-related issues, with 68.3% citing rigid leadership and unequal treatment as exacerbating risks. Insufficient staffing and protective devices, along with demanding work conditions, further heighten these hazards. This study emphasizes the need for targeted interventions in staffing, resources, and culture to improve radiology technologists' safety.</p>","PeriodicalId":56009,"journal":{"name":"Risk Management and Healthcare Policy","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531758/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Retrospective Analysis of Patients Presenting with Acute Hyperkalemia in an Emergency Care Setting.","authors":"Lei Zhang, Peng Sun, Xin Liu, Ya Yang, Ruo-Nan Sun, Xu-Dong Wang","doi":"10.2147/RMHP.S479582","DOIUrl":"10.2147/RMHP.S479582","url":null,"abstract":"<p><strong>Objective: </strong>We aimed to analyze the clinical characteristics and prognostic factors of patients with severe hyperkalemia in the emergency department.</p><p><strong>Methods: </strong>This retrospective cohort study included adult patients diagnosed with severe hyperkalemia who sought medical care at the emergency department of Aerospace Center Hospital between January 2018 and May 2022. Clinical data, including demographics, comorbidities, laboratory findings, and outcomes, were systematically collected. Patients were categorized into survival and deceased groups based on in-hospital mortality. Comparative analysis between these groups identified significant differences, highlighting key clinically covariates. Binary logistic regression was employed to determine the primary factors influencing patient outcomes.</p><p><strong>Results: </strong>Of 90 patients diagnosed with severe hyperkalemia, 64 were in the survival group, and 26 in the deceased group. Binary logistic regression identified several significant predictors of mortality, including higher APACHE II scores (odds ratio [OR] 1.41, <i>P</i> = 0.02), widened QRS wave on electrocardiogram (ECG) (OR 79.39, <i>P</i> = 0.04), and elevated serum potassium levels (OR 1.3, <i>P</i> = 0.04). In contrast, emergency blood purification was associated with a reduced mortality rate (OR 0.29, <i>P</i> = 0.03).</p><p><strong>Conclusion: </strong>Key risk factors for mortality in patients with severe hyperkalemia include widened QRS wave on ECG, elevated APACHE II score, and high serum potassium level. Timely correction of hyperkalemia through emergency blood purification significantly improves patient outcomes.</p>","PeriodicalId":56009,"journal":{"name":"Risk Management and Healthcare Policy","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Paroxysmal Atrial Tachycardia on Thromboembolic Events and Major Adverse Cardiovascular Events: A Single-Center Retrospective Study.","authors":"Peng Liu, Tingting Lv, Yuanwei Liu, Xiaofei Zhang, Fei She, Rong He, Dan Li, Lianfeng Liu, Ping Zhang","doi":"10.2147/RMHP.S482876","DOIUrl":"10.2147/RMHP.S482876","url":null,"abstract":"<p><strong>Objective: </strong>Atrial fibrillation (AF) is known to increase the risk of thromboembolic events and major adverse cardiovascular events (MACE). The impact of paroxysmal atrial tachycardia (PAT) on these risks remains unclear.</p><p><strong>Methods: </strong>This retrospective cohort study was conducted involving 889 patients diagnosed with PAT and 1106 control patients without PAT, all of whom underwent their initial 24-hour ECG monitoring between 2015 to 2020. Kaplan-Meier survival analysis and Cox regression analysis were used to evaluate the association between PAT and the study endpoints, including thromboembolic events and MACE.</p><p><strong>Results: </strong>Over a mean follow-up period of 50.3 months, the incidence of thromboembolic events and MACE was significantly higher in the PAT group compared to the control group (6.5% vs 1.7% and 19.1% vs 9.9%, respectively). After adjusting for common risk factors and baseline imbalances, the PAT group exhibited a significantly elevated risk of thromboembolic events (hazard ratio [HR] 3.782, 95% confidence interval [CI] 2.212-6.467; <i>P</i> <0.001) and MACE (HR 1.795, 95% CI 1.398-2.305; <i>P</i> <0.001). However, the frequency of PAT episodes, heart rate, and maximum heart rate were not significantly associated with these outcomes. Within the PAT group, a history of stroke, transient ischemic attack, and chronic renal failure were identified as independent risk factors for thromboembolic events, while hypertension, coronary heart disease, heart failure, and chronic renal failure were independently associated with MACE.</p><p><strong>Conclusion: </strong>PAT, as detected by 24-hour dynamic ECG, is associated with an increased risk of thromboembolic events and MACE.</p>","PeriodicalId":56009,"journal":{"name":"Risk Management and Healthcare Policy","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531291/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survey on the Current Status of Elderly Health Services in 1,305 Medical Institutions in Guangxi.","authors":"Dongmei Huang, Caizhong Zhou, Caili Li, Huiqiao Huang, Xiao Pan, Yanfei Pan, Qini Pan, Lichong Lai","doi":"10.2147/RMHP.S475319","DOIUrl":"10.2147/RMHP.S475319","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the current status of elderly health services in medical institutions at all levels within Guangxi Province, China.</p><p><strong>Methods: </strong>Using a purposeful sampling method, a questionnaire survey was conducted from July 24, 2023 to October 24, 2023 on the general situation, human resources, rehabilitation medicine, nursing services, and the development of hospice care at 1305 medical institutions in Guangxi.</p><p><strong>Results: </strong>Among the surveyed 1305 medical institutions in Guangxi, 172 (13.18%) had established departments of geriatrics, while 293 (22.45%) boasted departments of rehabilitation medicine. Furthermore, 909 (69.66%) of these institutions offered annual free physical examination services to individuals aged 65 and above. Notably, a total of 362 medical institutions, encompassing both comprehensive hospitals and grassroots hospitals, were recognized as elderly-friendly institutions, accounting for 31.4% of the surveyed sample.The highest demand for talents in medical institutions at all levels included specialized physicians/general practitioners (74.6%), traditional Chinese medicine practitioners (63.1%), rehabilitation therapists (56.1%), and specialized nurses for the elderly (41.7%). A total of 1038 medical institutions conducted popular science activities on elderly health, accounting for 79.5% of the total, focusing mainly on disease prevention (89.21%), nutritional diets (84.68%), rational medication use (79.77%), physical exercise (68.21%), and mental health (60.79%). Only 88 medical institutions provided hospice care services, accounting for 6.7% of the total.</p><p><strong>Conclusion: </strong>Guangxi medical institutions' elderly services are inadequate. Geriatrics and rehab departments are scarce, talent is lacking, and hospice care is underdeveloped. As aging accelerates, the country and society must support elderly care. Governments should introduce talent incentives, and medical institutions should enhance services, foster a positive work environment, and advance Guangxi's elderly health agenda.</p>","PeriodicalId":56009,"journal":{"name":"Risk Management and Healthcare Policy","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531266/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Attitude, and Practice Regarding Pharmacovigilance and Barriers to Reporting Adverse Drug Reactions Among the General Population in Saudi Arabia.","authors":"Hind Alshehri, Adnan Alharbi, Noof Alqethami, Mohammed Alnuhait, Abdullah Alshammari, Abdulmalik S Alotaibi","doi":"10.2147/RMHP.S484223","DOIUrl":"10.2147/RMHP.S484223","url":null,"abstract":"<p><strong>Background: </strong>Pharmacovigilance (PV) is an essential part of the healthcare system's framework. In Saudi Arabia, pharmacovigilance is still a relatively new concept though it is well established in many countries.</p><p><strong>Study aim: </strong>In this study, we aim to evaluate knowledge, attitude, and practice regarding pharmacovigilance and barriers to reporting adverse drug reactions (ADRs) among the general public in Saudi Arabia.</p><p><strong>Methods: </strong>This is a cross-sectional study that used a self-administered online questionnaire to assess knowledge, attitude, and practice of PV and ADRs. The study included only the adult population in Saudi Arabia. A scoring system was generated with a scale from 0 to 100, where 80% was set as a cut-off point, as any higher score resembled adequate knowledge, a positive attitude, and good practice. We used the Statistical Package for Social Sciences (SPSS) version 26 for performing the statistical analysis, where para-normal tests were used to associate scores with the socio-demographic characteristics of participants.</p><p><strong>Results: </strong>The study collected 1098 complete responses. The mean age (±SD) of participants was 37.9±11.2 years. Females comprised 68.9% of the participants. The average knowledge score among participants was 37.8±18.5, where only 4.3% of respondents had adequate knowledge. The average attitude score was 90.1±19.2, where 83.4% had a positive attitude. The average practice score was 70.4±18, and 34.5% of participants had good practice.</p><p><strong>Conclusion: </strong>The study found that the majority of participants had inadequate knowledge, a positive attitude, and poor practice. Individuals holding a master's degree or higher and those working in the healthcare sector had the highest knowledge scores, whereas the group aged 31 to 50 years old, participants from the Al Jawf region, participants who are married with children, holders of a master's degree or higher, and healthcare workers had the best attitude scores. Higher practice scores were seen among married individuals with children and those who work in the healthcare sector.</p>","PeriodicalId":56009,"journal":{"name":"Risk Management and Healthcare Policy","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531241/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Risk Factors Associated with Depressive Symptoms Among Healthcare Professionals at a Tertiary Care Hospital in Mogadishu, Somalia: A Cross-Sectional Study.","authors":"Nur Adam Mohamed, Yusuf Abdirisak Mohamed, Tigad Abdisad Ali, Adan Ali Gabow, Fartun Mohamed Hilowle","doi":"10.2147/RMHP.S488303","DOIUrl":"10.2147/RMHP.S488303","url":null,"abstract":"<p><strong>Background: </strong>Depression, a prevalent mental health issue, can significantly impact healthcare workers (HCWs), leading to decreased productivity, increased turnover, and high medical errors. However, there is a dearth of information regarding depression among healthcare professionals in Somalia. Therefore, this study aimed to assess the magnitude and risk factors associated with depressive symptoms among healthcare professionals in Mogadishu, Somalia.</p><p><strong>Methods: </strong>A hospital-based cross-sectional study was conducted among HCWs at Erdogan Hospital, in the capital city of Somalia. Data was collected using questionnaires on socio demographic, work-related characteristics and Patient Health Questionnaire-9 (PHQ-9). Bivariate and multivariate logistic regression analyses were conducted to identify variables associated with depressive symptoms. A p-values of 0.05 as a cutoff for a significant association.</p><p><strong>Results: </strong>The prevalence of depressive symptoms among healthcare professionals was 48.9% (95% CI: 45.4-56.9%). In multivariable analysis, being female (AOR = 2.05; 95% CI: 1.17-3.60), being a nurse (AOR = 3.11; 95% CI: 1.14-8.48), unmarried (AOR = 1.83; 95% CI: 1.04-3.21), having insufficient sleep (AOR = 2.61; 95% CI: 1.45-4.70), a family history of mental illness (AOR = 3.31; 95% CI: 1.49-7.36), lack of physical activity (AOR = 2.59; 95% CI: 1.19-5.62), and having low social support (AOR = 3.06; 95% CI: 1.17-7.98) were all associated with increased odds of experiencing depressive symptoms.</p><p><strong>Conclusion: </strong>The study showed that nearly half of healthcare professionals experienced depressive symptoms. The study underscores the importance of efficient screening methods for identifying psychological symptoms in healthcare professionals, which is essential for enhancing their mental health and patient care. Therefore, we recommend that healthcare institutions and policymakers develop and implement screening measures to identify and improve the mental health well-being of HCWs, as well as provide high-quality patient care.</p>","PeriodicalId":56009,"journal":{"name":"Risk Management and Healthcare Policy","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11529346/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attitudes Toward Intimate Partner Violence and Levels of Hope in University Students in Health-Related Departments.","authors":"Ayşe Gümüşler Başaran, Bahar Kefeli Çol, Burcu Genç Köse","doi":"10.2147/RMHP.S477798","DOIUrl":"10.2147/RMHP.S477798","url":null,"abstract":"<p><strong>Background: </strong>Intimate partner violence, is a major public and clinical health issue. Health institutions are one of the institutions to which a violence victim applies first. That is why the attitude of future health professionals is important. Hope is a concept that supports well-being and mental health. The aim of this study was to determine the relationship between attitudes towards intimate partner violence and hope levels of university students studying in the field of health.</p><p><strong>Methods: </strong>The research was a descriptive cross-sectional study. The research was carried out in December 2021 with 934 students. Data were collected using the sociodemographic data form, the acceptance of couple violence scale, and the trait hope scale.</p><p><strong>Results: </strong>%65 have a date or an ex-date, and %3.1 of them have experienced dating violence. 2.1% of the female students and 6.9% of the male students reported having experienced dating violence, and this was significantly higher in male students. Acceptance of couple violence among students are low in all dimensions. Acceptance of violence by men was significantly higher in all dimensions. Acceptance of male violence was significantly higher in those who use cigarettes and alcohol, and those who have experienced domestic or dating violence. The hope scale scores were close to high in all dimensions.</p><p><strong>Conclusion: </strong>The findings of the study showed the attitudes of students studying in health fields against violence. Students have dating relationships, are exposed to any violence in dating relationships, had low levels of acceptance of couple violence and high levels of hope. Students will start working with hope.</p>","PeriodicalId":56009,"journal":{"name":"Risk Management and Healthcare Policy","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11523974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Inflammatory Markers in Patients with COVID-19 Combined with Type 2 Diabetes Mellitus.","authors":"Jingjing Li, Yu Zhang, Rui Wu, Guodong Ma, Li Sheng, Yun Feng, Yang Han, Lina Zhang, Janfeng Guo, Rongbo Li","doi":"10.2147/RMHP.S490281","DOIUrl":"10.2147/RMHP.S490281","url":null,"abstract":"<p><strong>Purpose: </strong>To explore the value of different inflammatory markers in predicting the severity of coronavirus disease 2019 (COVID-19) in patients with type 2 diabetes mellitus (T2DM).</p><p><strong>Patients and methods: </strong>A total of 116 patients with COVID-19 in patients with T2DM were collected from December 2022 to March 2023 and were divided into a mild case group (77 cases) and a severe case group (39 cases). The ratio of neutrophil to lymphocyte (NLR), platelet-to-lymphocyte ratio (PLR), neutrophil to lymphocyte × platelet ratio (NLPR), lymphocyte ratio to monocyte (LMR), systemic inflammatory response index (SIRI), systemic inflammatory index (SII), systemic inflammatory composite index (AISI), procalcitonin (PCT), C-reactive protein (CRP) and lactate dehydrogenase (LDH) were compared between the two groups. The screening effect of each variable on the progression of the disease was analyzed using receiver operating characteristic (ROC) curves.</p><p><strong>Results: </strong>NLR, PLR, NLPR, MLR, SIRI, SII, AISI, LDH, CRP and PCT in severe case group were higher than those in mild case group (<i>P</i><0.05), and LMR was lower than those in mild case group (<i>P</i><0.05). ROC curve analysis further demonstrated the diagnostic performance of these biomarkers, with PCT having the largest area under the ROC curve (AUC^ROC) of 0.83.</p><p><strong>Conclusion: </strong>NLR, PLR, NLPR, SIRI, SII, LDH, CRP and PCT demonstrate greater reliability in diagnostic value and clinical utility for predicting the severity of COVID-19 in patients with T2DM.</p>","PeriodicalId":56009,"journal":{"name":"Risk Management and Healthcare Policy","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11523978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}