Acta Paediatrica最新文献_第3页

Neonatal Outcomes Among Neonates of Women With and Without Type 1 Diabetes in Sweden From 2010 to 2022. 2010年至2022年瑞典1型糖尿病女性和非1型糖尿病女性新生儿结局

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-07-15 DOI: 10.1111/apa.70230

Alexandra Goldberg, Eva Wiberg-Itzel, Joanna Tingström, Cecilia Ekéus

{"title":"Neonatal Outcomes Among Neonates of Women With and Without Type 1 Diabetes in Sweden From 2010 to 2022.","authors":"Alexandra Goldberg, Eva Wiberg-Itzel, Joanna Tingström, Cecilia Ekéus","doi":"10.1111/apa.70230","DOIUrl":"https://doi.org/10.1111/apa.70230","url":null,"abstract":"Aim: This register-based study aimed to investigate differences in adverse neonatal outcomes between neonates born to mothers with and without type 1 diabetes in Sweden.Methods: A nationwide cohort study was conducted using the Swedish Medical Birth Register, including all singleton births from 22 gestational weeks between 2010 and 2022. The neonatal outcomes among neonates of women with and without type 1 diabetes were studied with descriptive statistics and logistic regressions. Adjusted odds ratios (aORs) with 95% confidence intervals are presented.Results: The study consisted of 1 402 394 neonates, and 0.5% had a mother with type 1 diabetes. Neonates of mothers with type 1 diabetes had increased odds of stillbirth (aOR 2.54; 95% CI 1.98-3.28), congenital malformations (aOR 1.66; 95% CI 1.50-1.84), preterm birth (aOR 3.80; 95% CI 3.41-4.23), large for gestational age (aOR 22.0; 95% CI 20.9-23.1), hypoglycaemia (aOR 45.85; 95% CI 43.60-48.22), and neonatal death (aOR 4.1; 95% CI 3.00-5.83).Conclusion: Neonates of mothers with type 1 diabetes continue to experience poorer neonatal outcomes, highlighting the need for more research on the causes and how care can be improved for their mothers during pregnancy.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144644230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Issue Highlights 问题突出

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-07-14 DOI: 10.1111/apa.70203

Anna Käll, Hugo Lagercrantz

引用次数: 0

Turning the Tide on Childhood Overweight and Obesity: More Than a Decade of Positive Change Among 4-Year-Olds in Northern Sweden. 扭转儿童超重和肥胖的趋势：瑞典北部四岁儿童十多年来的积极变化。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-07-11 DOI: 10.1111/apa.70214

J Kuisma Löfbom, O Sandström, A Ivarsson, W Lohr, E Lundberg, S A Silfverdal, M Vaezghasemi

{"title":"Turning the Tide on Childhood Overweight and Obesity: More Than a Decade of Positive Change Among 4-Year-Olds in Northern Sweden.","authors":"J Kuisma Löfbom, O Sandström, A Ivarsson, W Lohr, E Lundberg, S A Silfverdal, M Vaezghasemi","doi":"10.1111/apa.70214","DOIUrl":"https://doi.org/10.1111/apa.70214","url":null,"abstract":"Aim: To study the development of overweight, obesity and underweight among 4-year-olds from 2007 to 2022, covering the COVID-19 pandemic period.Methods: This repeated cross-sectional analysis was conducted in Västerbotten County, northern Sweden. It used data on weight, height, age and sex, which were collected when children attended their 4-year check-ups at any of the 38 Child Health Centres.Results: The data comprised 42 614 4-year-old children (52% boys). From 2007 to 2022, the prevalence of overweight decreased from 13.4% to 9.5% in the boys and from 14.9% to 12.0% in the girls. The prevalence of obesity decreased from 3.7% to 1.8% in the boys and from 2.4% to 2.0% in the girls. During the first year of the COVID-19 pandemic, overweight and obesity temporarily increased for both the boys and girls, but the levels had returned to pre-pandemic levels by 2022. The prevalence of underweight increased among both boys and girls.Conclusion: Our study documents a decline in the prevalence of overweight and obesity among Swedish 4-year-olds over more than a decade, except for a surge during the early COVID-19 pandemic. Additionally, we observed an unexpected increase in the prevalence of underweight during the same period.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144621257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Respiratory Function Monitor-Are We Ready for Its Use? 呼吸功能监测仪——我们准备好使用它了吗？

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-07-10 DOI: 10.1111/apa.70227

Supreet Khurana

引用次数: 0

Normalising Vaccinations During Pregnancy Provides Benefits for Neonates and Infants. 怀孕期间疫苗接种正常化有利于新生儿和婴儿。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-07-10 DOI: 10.1111/apa.70225

Pauline F MacDonald

引用次数: 0

Streptococcus pneumoniae Remains Leading Cause of Bacteremia in Children Despite 13-Valent Pneumococcal Conjugate Vaccine Introduction. 尽管引入了13价肺炎球菌结合疫苗，但肺炎链球菌仍是儿童菌血症的主要原因。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-07-10 DOI: 10.1111/apa.70217

María Garrido Rodríguez, Ana María Borrull Senra, Susanna Hernández-Bou, Ane Artetxe Barroso, Bernat Servitje Verdaguer, Ángela Hurtado Mingo, Arístides Rivas García, Iris Collazo Vallduriola, Iker Gangoiti, Roberto Velasco, Mercedes de la Torre Espí, José Antonio Alonso-Cadenas

{"title":"Streptococcus pneumoniae Remains Leading Cause of Bacteremia in Children Despite 13-Valent Pneumococcal Conjugate Vaccine Introduction.","authors":"María Garrido Rodríguez, Ana María Borrull Senra, Susanna Hernández-Bou, Ane Artetxe Barroso, Bernat Servitje Verdaguer, Ángela Hurtado Mingo, Arístides Rivas García, Iris Collazo Vallduriola, Iker Gangoiti, Roberto Velasco, Mercedes de la Torre Espí, José Antonio Alonso-Cadenas","doi":"10.1111/apa.70217","DOIUrl":"https://doi.org/10.1111/apa.70217","url":null,"abstract":"Aim: To describe the epidemiology and primary diagnoses of previously healthy children aged 3-59 months who presented to paediatric emergency departments (PEDs) with a positive blood culture following the introduction of the publicly funded 13-valent pneumococcal conjugate vaccine (PCV13).Methods: We conducted a multicentre, cross-sectional, retrospective registry study in seven PEDs between 2017 and 2022. The findings were compared with those of a similar registry from 2011 to 2016.Results: During the funded PCV13 period, 278 patients were recorded. The most frequently isolated bacteria were Streptococcus pneumoniae (36.6%), Escherichia coli (12.6%), and Streptococcus pyogenes (29.4%). The most common diagnosis was focal infection (54.3%), followed by bacteremia without a focus of infection (26.6%), and severe invasive bacterial infection (19.1%). Poor outcomes were observed in 29.8% of patients. The most common serotypes during the funded PCV13 period were 10A, 24, and 8, none of which are included in PCV13.Conclusions: Streptococcus pneumoniae remained the leading cause of bacteremia in previously healthy children aged 3-59 months, with a predominance of non-vaccine serotypes. Although half of the patients had a localised infection, a substantial proportion developed severe invasive bacterial infections. Poor outcomes occurred in one out of every three to four invasive bacterial infections.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maternal Prenatal and Postnatal Stress and Infections in Infancy. 母亲产前和产后压力和婴儿感染。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-07-10 DOI: 10.1111/apa.70228

S Hyvönen, T Solasaari, T Pokka, K Korpela, W M de Vos, A Salonen, T Ruuska-Loewald, K-L Kolho

{"title":"Maternal Prenatal and Postnatal Stress and Infections in Infancy.","authors":"S Hyvönen, T Solasaari, T Pokka, K Korpela, W M de Vos, A Salonen, T Ruuska-Loewald, K-L Kolho","doi":"10.1111/apa.70228","DOIUrl":"https://doi.org/10.1111/apa.70228","url":null,"abstract":"Aim: To study maternal stress as a possible risk factor for early infections in infants in a well-characterised, prospective infant HELMi cohort.Methods: We measured maternal stress during the last trimester with questionnaires (4 items, scales 0-100) and breastmilk cortisol levels at 3 months. We compared maternal stress between infants with several infections (n = 125) and infants with no infections (n = 122) during the first 6 months of life. The episodes and days with symptoms were recorded using an online diary. Control subjects were matched for sex, year of birth, mode of delivery, and timing of breastmilk sample. The analysis was adjusted for season of birth and number of siblings.Results: The median maternal prenatal stress, related to household during the last trimester, was higher in the infection group than in controls (37 [IQR 19.5-61] vs. 19 [7.8-42.3]; p = 0.02). There was no difference in prenatal stress related to pregnancy or the relationship between the groups. The breastmilk cortisol levels did not differ between the groups (medians of 6.8 nmol/L [IQR 4.8-8.8] and 6.2 nmol/L [4.5-8.4], respectively; p = 0.12).Conclusion: Prenatal stress was linked to the occurrence of infections in infancy. Whether support for stress reduction may reduce the risk for infections warrants further study.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Children and Young Adults Who Used Medication for Attention Deficit Hyperactivity Disorder Faced Increased Cardiac Risks. 使用药物治疗注意力缺陷多动障碍的儿童和年轻人患心脏病的风险增加。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-07-09 DOI: 10.1111/apa.70215

Howaida Elmowafi, Jenny M Kindblom, Linda Halldner, David Gyllenberg, Estelle Naumburg

{"title":"Children and Young Adults Who Used Medication for Attention Deficit Hyperactivity Disorder Faced Increased Cardiac Risks.","authors":"Howaida Elmowafi, Jenny M Kindblom, Linda Halldner, David Gyllenberg, Estelle Naumburg","doi":"10.1111/apa.70215","DOIUrl":"https://doi.org/10.1111/apa.70215","url":null,"abstract":"Aim: There have been concerns about links between medication for attention deficit hyperactivity disorder (ADHD) and cardiac events in children and young people. Our aim was to identify any associations.Method: This Swedish case-control study used national register data to identify individuals aged 5-30 years who received their first diagnosis of a cardiac arrest, arrhythmia, fainting or collapse in 2006-2018. Each case was matched with five controls, by age, sex and region. Associations between ADHD medication and cardiac events were assessed using adjusted odds ratios (aORs) with 95% confidence intervals (CIs). Adjustments were made for concomitant medications and comorbidities, including congenital heart disease (CHD).Results: We studied 112 605 cases (57.9% female), with a median age of 20 years (range 5-30), and 563 024 matched controls. Using ADHD medication was associated with cardiac events (aOR 1.63, 95% CI 1.47-1.81) across sexes and age groups. Undefined arrhythmias had the strongest association (aOR 2.66, 95% CI 2.27-3.13). Cardiac arrests and defined arrhythmias had no associations. Long-term medication was associated with an increased risk (aOR 1.20, 95% CI 1.12-1.28). CHD had no impact.Conclusion: ADHD medication was associated with cardiac events, particularly undefined arrhythmias. CHD did not increase the risk.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144592993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surviving Extremely Low Birth Weight Infants Have a Higher Risk of ROP in Sub-Saharan Africa. 在撒哈拉以南非洲生存的极低出生体重婴儿有较高的ROP风险。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-07-07 DOI: 10.1111/apa.70216

Tshilidzi van der Lecq, Gerd Holmström, Esmè Jordaan, Gugulabatembunamahlubi Kali, Rudzani Muloiwa, Natasha Rhoda

{"title":"Surviving Extremely Low Birth Weight Infants Have a Higher Risk of ROP in Sub-Saharan Africa.","authors":"Tshilidzi van der Lecq, Gerd Holmström, Esmè Jordaan, Gugulabatembunamahlubi Kali, Rudzani Muloiwa, Natasha Rhoda","doi":"10.1111/apa.70216","DOIUrl":"https://doi.org/10.1111/apa.70216","url":null,"abstract":"Aim: Retinopathy of prematurity (ROP) risk factors have been investigated in population-based studies from most global regions. No such studies are available from Sub-Saharan Africa (SSA), where improved neonatal care is increasing the survival of preterm infants at risk of ROP.Methods: A population-based study was conducted in infants born in Cape Town, South Africa, from 1 May 2022 to 31 January 2023. The screening criteria were birth weight < 1250 g or gestational age < 32 weeks. The data were extracted from the Retinopathy of Prematurity South African register.Results: The study included 378 screened infants, 115 (30.4%) of whom developed ROP. In the multiple regression analyses, lower birth weight was an independent ROP risk factor, OR 1.3 95% CI 1.2-1.5, p < 0.001. Surgical necrotising enterocolitis (NEC) was the only other independent ROP risk factor, OR 5.8 95% CI 1.6-21.0, p = 0.007. Infants with birth weight < 1000 g were 39.4% (130/378) of those screened and more likely to develop ROP compared to larger infants, OR 2.4 95% CI 1.5-3.9, p < 0.001.Conclusion: Birth weight remained a significant ROP risk factor, especially for those born weighing less than 1000 g. These infants represented a larger proportion of screened infants compared to previous Sub-Saharan African studies.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Finland's Falling Birth Rate Prompts Study of Neonatal Outcomes in Secondary-Level Delivery Units. 芬兰出生率下降促使二级分娩单位新生儿结局研究。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-07-07 DOI: 10.1111/apa.70218

Ilari Kuitunen

引用次数: 0