Melissa A C M Kalden, Tom G Goos, Nico Kalden, Leo A Groenendaal, Irwin K M Reiss, Jasper Van Bommel, H Rob Taal
{"title":"The Physiological Effects of an Adjusted Alarm Architecture on a Neonatal Intensive Care Unit.","authors":"Melissa A C M Kalden, Tom G Goos, Nico Kalden, Leo A Groenendaal, Irwin K M Reiss, Jasper Van Bommel, H Rob Taal","doi":"10.1111/apa.70054","DOIUrl":"https://doi.org/10.1111/apa.70054","url":null,"abstract":"<p><strong>Aim: </strong>The effects of using handheld devices in combination with filtering and delaying alarms were investigated. Effects on the number of alarms, patient safety, and nurses' experience were evaluated.</p><p><strong>Methods: </strong>Alarm and physiological trend data were collected over two periods of three months for a control (n = 54) and intervention (n = 47) group. During the intervention period, an adapted alarm architecture, filtering and delaying alarms, was implemented, and the number of alarms, critical cardiorespiratory events, and episodes of decreased oxygen saturation and heart rate were compared to the contemporary alarm architecture. Nurses filled out a survey on their experiences.</p><p><strong>Results: </strong>The adapted alarm architecture reduced the number of alarms by 84%. This reduction did not result in significant differences in the number of critical events. Additionally, the duration and depth of the patient's episodes of mildly decreased oxygen saturation and heart rate were unaffected. Nurses reported that they continue to receive too many alarms and occasionally miss alarms.</p><p><strong>Conclusion: </strong>Alarms can be filtered and delayed, reducing the number of alarms and preventing alarm fatigue. Patient safety is not at risk since the number of critical events and the decreases in oxygen saturation and heart rate do not differ significantly between the groups.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143569114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea B Haijer-Schreuder, Emmalie A Jager, Terry G J Derks
{"title":"Is the Proof of the Pudding in the Fasting When It Comes to Rare Inherited Mitochondrial Fatty Acid Oxidation Disorders?","authors":"Andrea B Haijer-Schreuder, Emmalie A Jager, Terry G J Derks","doi":"10.1111/apa.70046","DOIUrl":"https://doi.org/10.1111/apa.70046","url":null,"abstract":"","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Flora D H Spring, Grith Lærkholm, Rikke Beck Jensen, Julie Tonsgaard Kloppenborg
{"title":"The Effect of Exergaming on BMI and Fitness in Children and Adolescents With Obesity: A Systematic Review.","authors":"Flora D H Spring, Grith Lærkholm, Rikke Beck Jensen, Julie Tonsgaard Kloppenborg","doi":"10.1111/apa.70048","DOIUrl":"https://doi.org/10.1111/apa.70048","url":null,"abstract":"<p><strong>Aim: </strong>Paediatric overweight and obesity are global health concerns linked to various physical and psychosocial challenges. Over the past decade, online games for exercise, exergames, have re-emerged in homes and schools as a possible solution to encourage physical activity and address childhood overweight and obesity. However, evidence on their effectiveness remains limited. This systematic review aimed to analyse the effects of exergaming on body mass index and physical activity in children and adolescents.</p><p><strong>Methods: </strong>Using keywords such as 'child', 'adolescent', 'obesity', 'overweight', 'exergaming' and 'active video gaming', a comprehensive search was conducted across PubMed and Embase, yielding 801 initial articles. Articles were screened following PRISMA guidelines and assessed using Covidence and Cochrane's quality assessment tools.</p><p><strong>Results: </strong>Twelve articles met the inclusion criteria. Sample sizes ranged from 29 to 445 participants, with intervention durations from 2 to 48 weeks. The results indicated that exergaming showed a subtle to moderate effect on body mass index and promising effects on moderate to vigorous physical activity.</p><p><strong>Conclusion: </strong>These findings suggest that exergames have potential as adjunctive tools in treating paediatric overweight and obesity. However, the limited number of studies and heterogeneity in the interventions highlight the need for further research in this field.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jason M Nagata, Gabriel Zamora, Jennifer H Wong, Abubakr A A Al-Shoaibi, Kyle T Ganson, Alexander Testa, Jinbo He, Jason M Lavender, Fiona C Baker
{"title":"Cyberbullying Victimisation Was Associated With Greater Manic Symptoms in Early Adolescence: A Prospective Cohort Study.","authors":"Jason M Nagata, Gabriel Zamora, Jennifer H Wong, Abubakr A A Al-Shoaibi, Kyle T Ganson, Alexander Testa, Jinbo He, Jason M Lavender, Fiona C Baker","doi":"10.1111/apa.70051","DOIUrl":"10.1111/apa.70051","url":null,"abstract":"<p><strong>Aim: </strong>Cyberbullying has been linked to various adverse psychological outcomes, but prospective associations with manic symptoms in early adolescents remain unexplored. We examined the prospective relationship between cyberbullying victimisation and manic symptoms in a diverse cohort of American children and adolescents.</p><p><strong>Method: </strong>We analysed data from the Adolescent Brain Cognitive Development study from the period 2 follow-up (2018-2020) to the period 3 follow-up (2019-2021). Linear regression models estimated the associations between cyberbullying victimisation (lifetime and past 12 months) and manic symptoms. We adjusted for age, sex, race and ethnicity, household income, parental education, manic symptoms, anxiety, depression, total screen time, and study site.</p><p><strong>Results: </strong>The average age of our 9095 adolescents (51.3% male) was 12.0 ± 0.7 years. The prevalence of cyberbullying victimisation was 9.2% for lifetime and 6.1% for the past 12 months. Adjusting for the covariates, lifetime cyberbullying victimisation was associated with a 0.41 higher manic symptom sum score (95% CI 0.18-0.65, p = 0.001), and past 12-month cyberbullying victimisation was associated with a 0.38 higher manic symptom sum score (95% CI 0.11-0.66, p = 0.007).</p><p><strong>Conclusion: </strong>These findings highlight the need for early identification and intervention for adolescents experiencing cyberbullying to mitigate its adverse effects on mental health.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Overall Decrease in Childhood Obesity in China-Monitoring of Childhood BMI Trends Is Crucial for Improved Public Health.","authors":"Jenny M Kindblom, Maria Bygdell","doi":"10.1111/apa.70047","DOIUrl":"https://doi.org/10.1111/apa.70047","url":null,"abstract":"","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J F Van Hoorn, S La Bastide-Van Gemert, M M Schoemaker, I Stuive, C K van der Sluis, M Hadders-Algra
{"title":"Causal Effects on Early Risk Factors of Developmental Coordination Disorder in the Dutch Lifelines Cohort.","authors":"J F Van Hoorn, S La Bastide-Van Gemert, M M Schoemaker, I Stuive, C K van der Sluis, M Hadders-Algra","doi":"10.1111/apa.70050","DOIUrl":"https://doi.org/10.1111/apa.70050","url":null,"abstract":"<p><strong>Aim: </strong>Limited information on early risk factors of Developmental Coordination Disorder (DCD) exists, especially in term-born children. We examined possible causal effects of early risk factors on DCD in predominantly term-born children.</p><p><strong>Methods: </strong>An add-on study to the Dutch Lifelines Cohort was performed in 2017. All 5-to-12-year-olds and their parents were included (n = 5479). Children were identified as at risk for DCD when the Developmental Coordination Disorder Questionnaire 2007 indicated suspicion of DCD, and as having probable DCD when another questionnaire, the DCD Daily Questionnaire, also suggested DCD. Causal graphs and multiple logistic regression models were used, including covariates sex, preterm birth (birth < 37 weeks), maternal education, parental subfertility, maternal smoking, and neonatal admission to the paediatric ward.</p><p><strong>Results: </strong>5479 children were identified; the response rate was 34% (n = 1856). 1722 children (50% male, 50% female sex; mean age 8.6 years) remained after exclusion for missing data. The prevalence of at risk for DCD and probable DCD was 13.0% (n = 223) and 5.9% (n = 100), respectively. Only male sex and neonatal admission to the paediatric ward had a direct causal effect on at risk for DCD and probable DCD.</p><p><strong>Conclusion: </strong>In the large Lifelines population, only male sex and neonatal admission were risk factors for DCD.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erwin Jiayuan Khoo, Mei Yoke Chan, Stefan Kutzsche, Eduard Verhagen
{"title":"Balancing Ethics and Equity: Rethinking Commercial Milk Formula Industry Partnerships in Maternal and Child Health.","authors":"Erwin Jiayuan Khoo, Mei Yoke Chan, Stefan Kutzsche, Eduard Verhagen","doi":"10.1111/apa.70053","DOIUrl":"https://doi.org/10.1111/apa.70053","url":null,"abstract":"","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Obituary for John Allen Clements, M.D., 1923-2024.","authors":"Joseph A Kitterman","doi":"10.1111/apa.70052","DOIUrl":"https://doi.org/10.1111/apa.70052","url":null,"abstract":"","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143538135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cardiorespiratory and Metabolic Responses to Daily Activities in Children: Examining Sex Differences and Weight Categories.","authors":"Narinrat Somwhong, Orawan Chareonphol, Papatsorn Ramyarangsi, Kotchakorn Jumroenketpratheep, Amornpan Ajjimaporn","doi":"10.1111/apa.70049","DOIUrl":"https://doi.org/10.1111/apa.70049","url":null,"abstract":"<p><strong>Aim: </strong>This study examined cardiorespiratory and metabolic responses to activities (supine rest, sitting, standing and walking) in children aged 6-12 years with normal weight, overweight and obesity, focusing on sex-specific differences. Overweight and obesity were categorised per World Health Organization criteria, emphasising their global health impact.</p><p><strong>Methods: </strong>Eighty-four children were classified by weight status and assessed for heart rate (HR), breathing frequency (BF), minute ventilation (VE), oxygen consumption (VO<sub>2</sub>), carbon dioxide production (VCO<sub>2</sub>), resting energy expenditure (REE) and metabolic equivalents (METs) during each activity. Statistical analyses compared responses across weight and sex groups.</p><p><strong>Results: </strong>HR, BF and VE increased with activity intensity in all groups. Boys with overweight and boys with obesity had significantly higher HR than boys with normal weight, reflecting greater cardiac strain. VO<sub>2</sub> and VCO<sub>2</sub> were elevated in children with obesity, particularly girls, indicating increased metabolic demands. Boys with overweight and boys with obesity exhibited higher VE/VO<sub>2</sub> and VE/VCO<sub>2</sub> ratios during low-intensity activities, reflecting reduced ventilatory efficiency.</p><p><strong>Conclusion: </strong>Strategies targeting respiratory and metabolic efficiency, including muscle strengthening and endurance exercises, are crucial for mitigating obesity-related strain, particularly in girls. These findings highlight the need for tailored, sex-specific interventions to address obesity in children.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143532237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rachel G Greenberg, Amii M Kress, Guojing Wu, J Wells Logan, Cindy T McEvoy, Frank Gilliland, Judy Aschner, Kecia N Carroll, Maria M Talavera-Barber, Margaret R Karagas, Maria José Rosa, Joanne Sordillo, P Brian Smith
{"title":"Association Between Prenatal Antibiotic Exposure and Infant Wheeze Outcomes.","authors":"Rachel G Greenberg, Amii M Kress, Guojing Wu, J Wells Logan, Cindy T McEvoy, Frank Gilliland, Judy Aschner, Kecia N Carroll, Maria M Talavera-Barber, Margaret R Karagas, Maria José Rosa, Joanne Sordillo, P Brian Smith","doi":"10.1111/apa.70044","DOIUrl":"10.1111/apa.70044","url":null,"abstract":"<p><strong>Aim: </strong>This study examined the association between antibiotic exposure during pregnancy and the development of wheezing and cough during infancy.</p><p><strong>Methods: </strong>We analysed data from 12 cohorts in the Environmental influences on Child Health Outcomes Cohort Consortium. Outcomes during the first 18 months after birth included the presence of wheeze or dry cough and treatment or intervention for these symptoms, including medications, emergency room visits, and hospitalisations. We used generalised estimating equations and logistic models with adjustment for inverse propensity scores for exposure to antibiotics.</p><p><strong>Results: </strong>A total of 4721 pregnancies were included, resulting in 4779 infants. Overall, 1,701/4,721 (36%) individuals received antibiotics during pregnancy, and wheezing was reported in 1,214/4,779 (26%) infants. In adjusted analyses, prenatal antibiotics were not associated with a higher odds of wheeze (OR = 1.06; 95% CI 0.91, 1.24) or hospitalisations or emergency room visits for wheeze or dry cough. However, prenatal antibiotic exposure was associated with a higher odds of medication use for wheeze or dry cough (OR = 1.62; 95% CI 1.10, 2.38).</p><p><strong>Conclusions: </strong>Prenatal antibiotic exposure may be associated with an increased odds of medication use for wheeze or dry cough during infancy but may not increase the risk of more severe events.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143517568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}