Acta Paediatrica最新文献_第3页

Towards Reaching Consensus in the Diagnosis and Management of Infants With Robin Sequence.

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-03-25 DOI: 10.1111/apa.70072

Christian F Poets, Mirja Quante, Cornelia Wiechers

引用次数: 0

Interventions by Clinical Pharmacists Reduced Unnecessary Antibiotics Exposure for Early-Onset Sepsis in a Neonatology Department.

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-03-25 DOI: 10.1111/apa.70070

Yao Yao, Nuo Qin, Dongmei Zhu, Jinhua Tang, Xiaoyun Zhong, Lin Chen

{"title":"Interventions by Clinical Pharmacists Reduced Unnecessary Antibiotics Exposure for Early-Onset Sepsis in a Neonatology Department.","authors":"Yao Yao, Nuo Qin, Dongmei Zhu, Jinhua Tang, Xiaoyun Zhong, Lin Chen","doi":"10.1111/apa.70070","DOIUrl":"https://doi.org/10.1111/apa.70070","url":null,"abstract":"Aim: To observe the effect of pharmacist-led antimicrobial stewardship (AMS) on antibiotic exposure for infants with suspected early-onset sepsis (EOS).Methods: A retrospective observational study was performed. The pharmacist was responsible for the development, education, and supervision of the implementation of the local EOS management protocol. In phase 1, the protocol was established completely according to the latest domestic consensus. In phase 2, the protocol was updated and defined which steps should be taken for specific risk factors and situations in which antibiotics were not necessary down to the detail.Results: A total of 9880 neonates were enrolled. The antibiotic use rate decreased from 58.1% before AMS was implemented to 51.9% in phase 1, and further to 31.7% in phase 2 (p < 0.0001). Days of therapy per 100 patient days were 30.8, 28.3, and 24.8, respectively (p < 0.0001). Multidrug-resistant organism culture rate gradually decreased from 48.2% to 45.5% in phase 1, and further to 37.0% in phase 2 (p < 0.01). No difference in safety outcomes was observed between the intervention and baseline periods.Conclusion: A practical AMS led by a pharmacist can safely and successfully reduce the prescription rate of antibiotics for EOS and the incidence of multidrug-resistant bacteria.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Implications of the New Criteria for a Positive Bronchodilator Response in Children With Asthma.

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-03-24 DOI: 10.1111/apa.70064

Caroline Stridsman, Helena Backman, Lowie E G W Vanfleteren, Anna Asarnoj, Henrik Ljungberg, Anne Lindberg, Apostolos Bossios, Jon R Konradsen

引用次数: 0

Factors Affecting the Relationship Between Total and Unbound Bilirubin in Preterm and Term Infants.

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-03-22 DOI: 10.1111/apa.70067

Thomas Hegyi, Dalya Chefitz, Alan Weller, Andrew Huber, Mary Carayannopoulos, William Oh, Alan Kleinfeld

{"title":"Factors Affecting the Relationship Between Total and Unbound Bilirubin in Preterm and Term Infants.","authors":"Thomas Hegyi, Dalya Chefitz, Alan Weller, Andrew Huber, Mary Carayannopoulos, William Oh, Alan Kleinfeld","doi":"10.1111/apa.70067","DOIUrl":"https://doi.org/10.1111/apa.70067","url":null,"abstract":"Aim: Newborn infants universally experience jaundice, most of which is physiologic, but in some high-risk situations, it may lead to neurological dysfunction or death. Unbound bilirubin (Bf) may be the best predictor of bilirubin toxicity in this population. The goal of the study is to examine the relationship between total serum bilirubin (TSB) and Bf and the influencing factors.Methods: To calculate the relationship of Bf to TSB, we created a ratio (R) Bf/TSB × 106 to allow the comparison of products with varied concentrations. We then applied it to simultaneously obtain TSB and Bf measurements in infants to examine the influence of prematurity, haemolysis, feeding (breast or bottle feedings) and phototherapy. We also examined R at potential toxic Bf levels in the preterm group.Results: The population consisted of 170 term and 130 preterm infants. The R was 3.64 ± 1.08 (SD) in term and 15.18 ± 9.8 in preterm infants. Prematurity and high TSB that required phototherapy significantly increased R. Higher R-values were seen at higher Bf toxic threshold levels.Conclusion: An R-value can reflect the relationship between Bf and TSB. The values are greater in prematurity and in infants with high TSB, which requires phototherapy.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143677423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Welcomed Assessment of Breastfeeding Supports Growth in Small for Gestational Age Infants: A Systematic Review and Meta-Analysis.

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-03-19 DOI: 10.1111/apa.70056

Heather Resvick, Amber Foster, Brenda Hartman, Orlando daSilva, Kevin Coughlin, Janet Madill

引用次数: 0

Neurodevelopment and Associated Factors in Preterm Infants Who Received Kangaroo Mother Care: A 12-Month Follow-Up.

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-03-19 DOI: 10.1111/apa.70065

Gilles Ndjomo, Sylvie Blairy, Erero Njiengwe, Marie Geurten

{"title":"Neurodevelopment and Associated Factors in Preterm Infants Who Received Kangaroo Mother Care: A 12-Month Follow-Up.","authors":"Gilles Ndjomo, Sylvie Blairy, Erero Njiengwe, Marie Geurten","doi":"10.1111/apa.70065","DOIUrl":"https://doi.org/10.1111/apa.70065","url":null,"abstract":"Aim: Document the predictive factors for neurodevelopment up to the corrected age of 12 months for infants who received Kangaroo Mother Care (KMC).Methods: In total, 91 preterm infants and their 78 mothers were included in the study. Maternal symptoms, maternal compliance with KMC practices and infant characteristics and development were recorded.Results: Compared with formula and mixed milk, breast milk was associated with better developmental outcomes in locomotor (ß = 19.38, t = 4.21, p < 0.001), personal-social (ß = 19.39, t = 5.43, p < 0.001), hearing and speech (ß = 14.1, t = 3.6, p < 0.001), eye and hand coordination (ß = 17.31, t = 4.53, p < 0.001) and performance (ß = 11.21, t = 2.77, p = 0.006) subscales of the Griffith Mental Development Scales. However, the daily skin-to-skin contact (SSC) duration was negatively related to the locomotor (ß = -5.17, t = -2.04, p = 0.046), personal-social (ß = -4.92, t = -2.85, p = 0.007), hearing and speech (ß = -4.88, t = -2.63, p = 0.012), eye and hand coordination (ß = -4.77, t = -2.43, p = 0.018), and performance (ß = -5.67, t = -2.92, p = 0.007) subscales. The negative effect of SSC duration was moderated by the severity of maternal depressive symptoms.Conclusion: Promoting breast milk and treating maternal depression could contribute to positive neurodevelopment in preterm infants.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143658983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Portable Bedside Nasal Continuous Positive Airway Pressure in the Delivery Room Reduces Length of Stay.

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-03-18 DOI: 10.1111/apa.70062

Stephanie Balslev Andersen, Janne Eriksen, Anne-Cathrine Finnemann Viuff, Lia Mendes Pedersen, Ninna Brix

{"title":"Portable Bedside Nasal Continuous Positive Airway Pressure in the Delivery Room Reduces Length of Stay.","authors":"Stephanie Balslev Andersen, Janne Eriksen, Anne-Cathrine Finnemann Viuff, Lia Mendes Pedersen, Ninna Brix","doi":"10.1111/apa.70062","DOIUrl":"https://doi.org/10.1111/apa.70062","url":null,"abstract":"Aim: Portable bedside nasal continuous positive airway pressure in the delivery room (bedside nCPAP) allows the newborn infant to remain with the mother in the delivery room while receiving nCPAP. This study aimed to evaluate the duration of nCPAP treatment and length of stay (LOS) in newborn infants with respiratory distress receiving bedside nCPAP compared to nCPAP in the neonatal intensive care unit (NICU).Methods: This retrospective cohort study comprised newborn infants born at ≥ 35 weeks of gestation requiring nCPAP treatment within the first 2 h of life due to respiratory distress. Data were collected from October 2011 to October 2020 at Aalborg University Hospital, Denmark.Results: Bedside nCPAP was administered to 225 newborn infants, while 185 newborn infants received nCPAP at the NICU. Newborn infants receiving bedside nCPAP had a shorter duration of CPAP treatment (4.4 vs. 7.3 h, p < 0.001) and LOS (7.2 vs. 20.2 h, p < 0.001). Transfer to the NICU was avoided in 72% of newborn infants receiving bedside nCPAP.Conclusion: Bedside nCPAP reduces the duration of CPAP treatment and LOS compared to nCPAP in the NICU. About 72% of newborn infants receiving bedside nCPAP avoided transfer to the NICU and avoided separation from their mothers.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neonatal Transport is an Important Factor in Centralised Extremely Preterm Births and Early Postnatal Mortality.

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-03-11 DOI: 10.1111/apa.70060

Carlo Bellini

引用次数: 0

Bundle-Of-Care vs. Single-Intervention RCTs in Neonatology: Clinical Research in Neonatology-Quo Vadis?

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-03-10 DOI: 10.1111/apa.70057

Sascha Meyer, Martin Poryo, Axel R Franz, Christian F Poets

引用次数: 0

Psychometric Evaluation of the Swedish Version of the Child Behaviour Check List (CBCL) 1.5-5.

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-03-08 DOI: 10.1111/apa.70058

Stefan Nasir, Emma Fransson, Hans Arinell, F C Papadopoulos, Alkistis Skalkidou, Mia Ramklint

{"title":"Psychometric Evaluation of the Swedish Version of the Child Behaviour Check List (CBCL) 1.5-5.","authors":"Stefan Nasir, Emma Fransson, Hans Arinell, F C Papadopoulos, Alkistis Skalkidou, Mia Ramklint","doi":"10.1111/apa.70058","DOIUrl":"https://doi.org/10.1111/apa.70058","url":null,"abstract":"Aim: Examine the psychometric properties of the Swedish Child Behaviour Check List (CBCL) 1.5-5.Methods: CBCL 1.5-5 responses were collected from 1156 mothers about their 18-month-old children in a population-based study. Representation was analysed by comparing the study sample with two Swedish national samples; scores were reweighted to adjust for selection bias. Confirmatory factor analysis was done using Robust Maximum Likelihood (MLR) estimation on CBCL 1.5-5 syndrome scales and Diagonally Weighted Least Squares (DWLS) estimation for item level. Test-retest reliability was examined with the Pearson (r) coefficient in a subsample (n = 80). Convergent validity was tested between CBCL 1.5-5 and the Early Childhood Behaviour Questionnaire (ECBQ) Very Short Form (n = 826).Results: Internal consistency of the CBCL scales varied, McDonald's Omega (ω) 0.5-0.9. Confirmatory factor analysis showed good factor fit for seven factors. Test-retest reliability for the Total Problem Score (TPS), Internalising Problems Score (IPS) and Externalising Problems Score (EPS) scales after 4-12 months was r = 0.53, 0.43 and 0.53. Convergence validity was tested between the CBCL 1.5-5 EPS scale and the Early Childhood Behaviour Questionnaire (ECBQ) Effortful control scale (r = -0.51), and the CBCL 1.5-5 IPS scale and ECBQ Negative Affectivity scale (r = 0.45).Conclusion: The Swedish translation of CBCL 1.5-5 showed good psychometric properties.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0