Valdemar Landgren, Rajna Knez, David Karlsson, Samuel Fernmo, Mats Johnson, Leif Svensson, Magnus Landgren
{"title":"Prevalence of Fetal Alcohol Spectrum Disorders: A Pilot Study in Western Sweden.","authors":"Valdemar Landgren, Rajna Knez, David Karlsson, Samuel Fernmo, Mats Johnson, Leif Svensson, Magnus Landgren","doi":"10.1111/apa.70059","DOIUrl":"https://doi.org/10.1111/apa.70059","url":null,"abstract":"<p><strong>Aim: </strong>To develop and trial a method for estimating the prevalence of fetal alcohol spectrum disorders (FASD) in Sweden.</p><p><strong>Methods: </strong>A school-based study with a full physical examination, including a dysmorphology assessment, neuropsychological testing, behavioural ratings, academic evaluation and maternal nutritional interview conducted as an add-on to the regular health check-up in 4th grade.</p><p><strong>Results: </strong>Out of 348 eligible children, 223 participated. In the 206 children with a dysmorphological evaluation, 9.2% (n = 19) met criteria for a fetal alcohol spectrum disorder, with alcohol-related neurodevelopmental disorder accounting for 4.9% (n = 10), fetal alcohol syndrome for 2.4% (n = 5) and partial fetal alcohol syndrome for 1.9% (n = 4). According to the conservative method using all eligible children as the denominator, the prevalence of FASD was 5.5% (95% confidence interval [CI] 3.3-8.4) and fetal alcohol syndrome 1.4% (95% CI 0.5-3.3).</p><p><strong>Conclusion: </strong>The lowest prevalence estimate of FASD in Sweden is similar to that found in other European countries, and four orders of magnitude more common than the prevalence of the diagnosis in official hospital records. A screening procedure for large-scale studies may utilise both behavioural and anthropometric measures, including head circumference, depending on the objective.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143588386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Selma Mujezinović Larsen, Kjersti Ramstad, Sandra Julsen Hollung, Guro L Andersen, Trond H Diseth
{"title":"Higher Self-Than Parent-Reported Health-Related Quality of Life in Adolescents With Cerebral Palsy; a Register Study.","authors":"Selma Mujezinović Larsen, Kjersti Ramstad, Sandra Julsen Hollung, Guro L Andersen, Trond H Diseth","doi":"10.1111/apa.70055","DOIUrl":"https://doi.org/10.1111/apa.70055","url":null,"abstract":"<p><strong>Aim: </strong>To investigate health-related quality of life (HRQoL) in adolescents with cerebral palsy (CP), compare self-reporting with parental proxy-reporting and identify factors associated with low HRQoL.</p><p><strong>Methods: </strong>Adolescents aged 15-17 years with normal to mildly impaired cognitive function enrolled in the Norwegian Quality and Surveillance Registry for CP were eligible. Adolescents with both self- and parental proxy-report on HRQoL (Paediatric Quality of Life; PedsQL) were included. Self- and proxy-reported physical and psychosocial domain HRQoL scores were analysed for associations by sex, mobility, pain and mental health (Strengths and Difficulties Questionnaire; SDQ).</p><p><strong>Results: </strong>Seventy-two adolescent-parent HRQoL dyads were retrieved. Self-reported HRQoL was higher than parental proxy-reported HRQoL in all domains. Females reported lower HRQoL. A higher level of mobility was associated with higher physical, but not with higher psychosocial functioning in both self- and proxy-reports. Pain was associated with decreased proxy-reported psychosocial functioning. Increased SDQ total difficulties scores were associated with decreased self- and proxy-reported psychosocial functioning and proxy-reported physical functioning.</p><p><strong>Conclusion: </strong>Adolescents with CP reported a higher HRQoL than their parents proxy-reported. The severity of motor impairment was not associated with psychosocial well-being. Mental health issues decreased both self- and parental proxy-reported HRQoL. Pain decreased parental proxy-reported HRQoL.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Melissa A C M Kalden, Tom G Goos, Nico Kalden, Leo A Groenendaal, Irwin K M Reiss, Jasper Van Bommel, H Rob Taal
{"title":"The Physiological Effects of an Adjusted Alarm Architecture on a Neonatal Intensive Care Unit.","authors":"Melissa A C M Kalden, Tom G Goos, Nico Kalden, Leo A Groenendaal, Irwin K M Reiss, Jasper Van Bommel, H Rob Taal","doi":"10.1111/apa.70054","DOIUrl":"https://doi.org/10.1111/apa.70054","url":null,"abstract":"<p><strong>Aim: </strong>The effects of using handheld devices in combination with filtering and delaying alarms were investigated. Effects on the number of alarms, patient safety, and nurses' experience were evaluated.</p><p><strong>Methods: </strong>Alarm and physiological trend data were collected over two periods of three months for a control (n = 54) and intervention (n = 47) group. During the intervention period, an adapted alarm architecture, filtering and delaying alarms, was implemented, and the number of alarms, critical cardiorespiratory events, and episodes of decreased oxygen saturation and heart rate were compared to the contemporary alarm architecture. Nurses filled out a survey on their experiences.</p><p><strong>Results: </strong>The adapted alarm architecture reduced the number of alarms by 84%. This reduction did not result in significant differences in the number of critical events. Additionally, the duration and depth of the patient's episodes of mildly decreased oxygen saturation and heart rate were unaffected. Nurses reported that they continue to receive too many alarms and occasionally miss alarms.</p><p><strong>Conclusion: </strong>Alarms can be filtered and delayed, reducing the number of alarms and preventing alarm fatigue. Patient safety is not at risk since the number of critical events and the decreases in oxygen saturation and heart rate do not differ significantly between the groups.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143569114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea B Haijer-Schreuder, Emmalie A Jager, Terry G J Derks
{"title":"Is the Proof of the Pudding in the Fasting When It Comes to Rare Inherited Mitochondrial Fatty Acid Oxidation Disorders?","authors":"Andrea B Haijer-Schreuder, Emmalie A Jager, Terry G J Derks","doi":"10.1111/apa.70046","DOIUrl":"https://doi.org/10.1111/apa.70046","url":null,"abstract":"","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Flora D H Spring, Grith Lærkholm, Rikke Beck Jensen, Julie Tonsgaard Kloppenborg
{"title":"The Effect of Exergaming on BMI and Fitness in Children and Adolescents With Obesity: A Systematic Review.","authors":"Flora D H Spring, Grith Lærkholm, Rikke Beck Jensen, Julie Tonsgaard Kloppenborg","doi":"10.1111/apa.70048","DOIUrl":"https://doi.org/10.1111/apa.70048","url":null,"abstract":"<p><strong>Aim: </strong>Paediatric overweight and obesity are global health concerns linked to various physical and psychosocial challenges. Over the past decade, online games for exercise, exergames, have re-emerged in homes and schools as a possible solution to encourage physical activity and address childhood overweight and obesity. However, evidence on their effectiveness remains limited. This systematic review aimed to analyse the effects of exergaming on body mass index and physical activity in children and adolescents.</p><p><strong>Methods: </strong>Using keywords such as 'child', 'adolescent', 'obesity', 'overweight', 'exergaming' and 'active video gaming', a comprehensive search was conducted across PubMed and Embase, yielding 801 initial articles. Articles were screened following PRISMA guidelines and assessed using Covidence and Cochrane's quality assessment tools.</p><p><strong>Results: </strong>Twelve articles met the inclusion criteria. Sample sizes ranged from 29 to 445 participants, with intervention durations from 2 to 48 weeks. The results indicated that exergaming showed a subtle to moderate effect on body mass index and promising effects on moderate to vigorous physical activity.</p><p><strong>Conclusion: </strong>These findings suggest that exergames have potential as adjunctive tools in treating paediatric overweight and obesity. However, the limited number of studies and heterogeneity in the interventions highlight the need for further research in this field.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jason M Nagata, Gabriel Zamora, Jennifer H Wong, Abubakr A A Al-Shoaibi, Kyle T Ganson, Alexander Testa, Jinbo He, Jason M Lavender, Fiona C Baker
{"title":"Cyberbullying Victimisation Was Associated With Greater Manic Symptoms in Early Adolescence: A Prospective Cohort Study.","authors":"Jason M Nagata, Gabriel Zamora, Jennifer H Wong, Abubakr A A Al-Shoaibi, Kyle T Ganson, Alexander Testa, Jinbo He, Jason M Lavender, Fiona C Baker","doi":"10.1111/apa.70051","DOIUrl":"10.1111/apa.70051","url":null,"abstract":"<p><strong>Aim: </strong>Cyberbullying has been linked to various adverse psychological outcomes, but prospective associations with manic symptoms in early adolescents remain unexplored. We examined the prospective relationship between cyberbullying victimisation and manic symptoms in a diverse cohort of American children and adolescents.</p><p><strong>Method: </strong>We analysed data from the Adolescent Brain Cognitive Development study from the period 2 follow-up (2018-2020) to the period 3 follow-up (2019-2021). Linear regression models estimated the associations between cyberbullying victimisation (lifetime and past 12 months) and manic symptoms. We adjusted for age, sex, race and ethnicity, household income, parental education, manic symptoms, anxiety, depression, total screen time, and study site.</p><p><strong>Results: </strong>The average age of our 9095 adolescents (51.3% male) was 12.0 ± 0.7 years. The prevalence of cyberbullying victimisation was 9.2% for lifetime and 6.1% for the past 12 months. Adjusting for the covariates, lifetime cyberbullying victimisation was associated with a 0.41 higher manic symptom sum score (95% CI 0.18-0.65, p = 0.001), and past 12-month cyberbullying victimisation was associated with a 0.38 higher manic symptom sum score (95% CI 0.11-0.66, p = 0.007).</p><p><strong>Conclusion: </strong>These findings highlight the need for early identification and intervention for adolescents experiencing cyberbullying to mitigate its adverse effects on mental health.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Overall Decrease in Childhood Obesity in China-Monitoring of Childhood BMI Trends Is Crucial for Improved Public Health.","authors":"Jenny M Kindblom, Maria Bygdell","doi":"10.1111/apa.70047","DOIUrl":"https://doi.org/10.1111/apa.70047","url":null,"abstract":"","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J F Van Hoorn, S La Bastide-Van Gemert, M M Schoemaker, I Stuive, C K van der Sluis, M Hadders-Algra
{"title":"Causal Effects on Early Risk Factors of Developmental Coordination Disorder in the Dutch Lifelines Cohort.","authors":"J F Van Hoorn, S La Bastide-Van Gemert, M M Schoemaker, I Stuive, C K van der Sluis, M Hadders-Algra","doi":"10.1111/apa.70050","DOIUrl":"https://doi.org/10.1111/apa.70050","url":null,"abstract":"<p><strong>Aim: </strong>Limited information on early risk factors of Developmental Coordination Disorder (DCD) exists, especially in term-born children. We examined possible causal effects of early risk factors on DCD in predominantly term-born children.</p><p><strong>Methods: </strong>An add-on study to the Dutch Lifelines Cohort was performed in 2017. All 5-to-12-year-olds and their parents were included (n = 5479). Children were identified as at risk for DCD when the Developmental Coordination Disorder Questionnaire 2007 indicated suspicion of DCD, and as having probable DCD when another questionnaire, the DCD Daily Questionnaire, also suggested DCD. Causal graphs and multiple logistic regression models were used, including covariates sex, preterm birth (birth < 37 weeks), maternal education, parental subfertility, maternal smoking, and neonatal admission to the paediatric ward.</p><p><strong>Results: </strong>5479 children were identified; the response rate was 34% (n = 1856). 1722 children (50% male, 50% female sex; mean age 8.6 years) remained after exclusion for missing data. The prevalence of at risk for DCD and probable DCD was 13.0% (n = 223) and 5.9% (n = 100), respectively. Only male sex and neonatal admission to the paediatric ward had a direct causal effect on at risk for DCD and probable DCD.</p><p><strong>Conclusion: </strong>In the large Lifelines population, only male sex and neonatal admission were risk factors for DCD.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erwin Jiayuan Khoo, Mei Yoke Chan, Stefan Kutzsche, Eduard Verhagen
{"title":"Balancing Ethics and Equity: Rethinking Commercial Milk Formula Industry Partnerships in Maternal and Child Health.","authors":"Erwin Jiayuan Khoo, Mei Yoke Chan, Stefan Kutzsche, Eduard Verhagen","doi":"10.1111/apa.70053","DOIUrl":"https://doi.org/10.1111/apa.70053","url":null,"abstract":"","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Obituary for John Allen Clements, M.D., 1923-2024.","authors":"Joseph A Kitterman","doi":"10.1111/apa.70052","DOIUrl":"https://doi.org/10.1111/apa.70052","url":null,"abstract":"","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143538135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}