Acta Paediatrica最新文献

{"title":"Improved Paediatric Procedural Competence and Knowledge After Training Using a Newborn Piglet Model.","authors":"Kasper Jacobsen Kyng, Anna Holst Møller, Torjus Skajaa, Sigrid Kerrn-Jespersen, Kristine Bennedsgaard, Sune Rubak, Rikke Kaae, Tine Brink Henriksen","doi":"10.1111/apa.70309","DOIUrl":"https://doi.org/10.1111/apa.70309","url":null,"abstract":"<p><strong>Aim: </strong>Training complex paediatric procedural skills is essential for patient safety. Clinical learning opportunities are rare, and a live model offers realistic tissue with a dynamic physiology. We aimed to develop and evaluate a procedural skills course using a newborn piglet model for trainees in paediatrics.</p><p><strong>Methods: </strong>We designed four modules with learning goals, procedural checklists and learning outcome assessment. Eight courses were held including 23 junior trainee doctors, 34 experienced trainees and four neonatal specialist doctors.</p><p><strong>Results: </strong>Most procedures were successfully completed by all trainees. Mean multiple-choice test scores improved 36% (95% confidence interval [CI] 31-41) after the intervention. Self-rated competence improved 78% in junior and 65% in experienced trainees (95% CI: 62-93 and 53-77). Experienced trainees improved most in difficult skills such as chest tube placement and endotracheal intubation. Junior trainees improved most in basic skills such as umbilical catheter placement. All modules received high scores for clinical relevance and transferability.</p><p><strong>Conclusion: </strong>We established a procedural skills course that improved test scores and self-rated procedural competence. Participants reported a high degree of transferability to actual clinical procedures.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145082489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Childhood Active Play Is Not the Same as 'Sport & Exercise'.","authors":"Nikoleta Odorico","doi":"10.1111/apa.70307","DOIUrl":"https://doi.org/10.1111/apa.70307","url":null,"abstract":"","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EBNEO Commentary: Late Permissive Hypercapnia for Mechanically Ventilated Preterm Infants.","authors":"Thomas M Raffay, Rita M Ryan","doi":"10.1111/apa.70297","DOIUrl":"https://doi.org/10.1111/apa.70297","url":null,"abstract":"","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Global North-South Paradox: Rickets in Sunny Countries.","authors":"Chandra Sekhar Devulapalli","doi":"10.1111/apa.70305","DOIUrl":"https://doi.org/10.1111/apa.70305","url":null,"abstract":"","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Swedish Infants Developed Pertussis at a Younger Age if Their Mother Was the Possible Source of Infection in 2009-2015.","authors":"Bernice Aronsson, Lennart Nilsson, Jann Storsaeter, Henrik Källberg, Emma Appelqvist","doi":"10.1111/apa.70300","DOIUrl":"https://doi.org/10.1111/apa.70300","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this study was to investigate the possible source of laboratory-confirmed pertussis in infants under 6 months of age.</p><p><strong>Methods: </strong>This nationwide prospective study was based on laboratory-confirmed cases reported in the enhanced pertussis surveillance in Sweden from 2009 to 2015. The parents or carers of 345 infants were interviewed about their clinical details including the age at onset and disease severity. They were also asked to state who had been in contact with the infant prior to onset, in order to identify possible sources of infection.</p><p><strong>Results: </strong>Only one possible source of infection was identified for 191 infants and the mother was presumed to be the source in 33%. These 63 cases showed different characteristics from those where a father, sibling, someone outside the immediate family or two to three people were identified as possible sources of infection. They were significantly younger, with a median of 31 days of age at onset (p < 0.01), and their hospitalisation rate (79%) was significantly higher (p < 0.01).</p><p><strong>Conclusion: </strong>Our results support general maternal vaccination against pertussis. Other preventive measures also need to be strengthened and implemented to prevent severe pertussis disease in the youngest infants with higher risk of death.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurodevelopmental Outcomes of Very Low Birth Weight Infants With Transient Hypothyroxinaemia of Prematurity.","authors":"Sophie S L Yeow, Charis H Y Chung, Wilfred H S Wong, Khair Jalal, Mabel S C Wong, Wing-Shan Queenie See","doi":"10.1111/apa.70302","DOIUrl":"https://doi.org/10.1111/apa.70302","url":null,"abstract":"<p><strong>Aim: </strong>Transient hypothyroxinaemia of prematurity affects very low birth weight (VLBW) infants born prematurely. The relationship between transient hypothyroxinaemia of prematurity (THOP) and adverse neurodevelopmental outcomes is still controversial. The present study aimed to compare the neurodevelopmental outcomes between those with VLBW infants with THOP and those without.</p><p><strong>Methods: </strong>This was a single tertiary neonatal centre retrospective study comparing the neurodevelopmental outcome using Griffiths Mental Development Scales-Extended Revised between VLBW infants (birth weight less than or equal to 1500 g) with THOP to those without based on one-to-one age and gender matching from 2011 to 2021.</p><p><strong>Result: </strong>Forty-two VLBW infants with THOP and 42 VLBW infants without THOP were matched by age and gender. None of the infants with THOP received thyroxine supplementation. The prevalence of THOP is 6.86%. The mortality rate for infants with THOP was 14.3%. There was no significant difference in neonatal complications and neurodevelopmental outcomes between infants with THOP (70%) and infants without THOP (70.7%).</p><p><strong>Conclusion: </strong>We showed that there was no difference in neurodevelopmental outcomes between those with THOP without thyroxine supplementation and those without THOP.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond Coverage: Policy Lessons From Socioeconomic Gaps in Paediatric Vaccine Access.","authors":"Tiago Santos Trindade, Catarina Cabral Oliveira, Marta Rodrigues Amaral, Nádia Costa, Maria Alice Oliveira, Virgínia Monteiro, Miguel Costa","doi":"10.1111/apa.70299","DOIUrl":"https://doi.org/10.1111/apa.70299","url":null,"abstract":"","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Issue Highlights","authors":"Anna Käll,&nbsp;Hugo Lagercrantz","doi":"10.1111/apa.70284","DOIUrl":"https://doi.org/10.1111/apa.70284","url":null,"abstract":"<p>In an intervention involving 93 parents of infants treated in a Canadian neonatal care unit (NICU), the parents received physical certificates and text messages each week celebrating their baby's milestones. An evaluation showed that parents appreciated the intervention, which helped them cope with the hospital experience and provided feelings of empowerment, patience, and hope [<span>1</span>].</p><p>Physical activity and screen time were evaluated among children aged 4–17 in Sweden before, during, and after the COVID-19 pandemic in a study by Kägi-Braun et al. [<span>2</span>]. They found that screen time increased during COVID-19 and remained high afterward. In contrast, physical activity trends were more difficult to interpret but tended to be lower during the pandemic before levelling off after the pandemic. In an editorial, Sisela Nutley comments that increased screen time at the population level is concerning for several reasons [<span>3</span>].</p><p>Turkish healthcare staff faced significant challenges managing paediatric trauma patients after the major 2023 Kahramanmaras earthquakes, which killed more than 50 000 people. Aslan et al. describe how their large referral centre treated complex cases [<span>4</span>]. Crush syndrome, compartment syndrome and acute kidney injuries were the most common complications after the earthquake. The authors conclude that an effective disaster response plan, multidisciplinary management and early intervention were essential for optimising outcomes.</p><p>The accuracy of urinalysis in identifying infants with bacteremic urinary tract infections (UTIs) is limited, according to a retrospective multicentre study. It involved 110 infants aged 0–3 months with bacteraemic UTIs [<span>5</span>]. Cases of bacteraemic UTI with normal urinalysis results were observed across both genders, various age groups and different pathogens. Heno et al. concluded that relying solely on urinalysis to rule out UTI in infants may lead to significant underdiagnosis. Readers may also be interested in the study by Hakkola et al. on abnormal ultrasound findings following a UTI [<span>6</span>], as well as the paper by González-Anleo et al. on risk factors for multidrug-resistant catheter-associated UTIs [<span>7</span>].</p><p>Vomiting after oral administration of medication is common in children. When it happens, there is often uncertainty about the absorption of the given dose and whether to re-dose or not. Despite this, there has been a lack of formal guidelines and recommendations on this topic. Garnemark et al have now developed a decision support tool, intended for doctors and nurses to support the management of this everyday clinical dilemma [<span>8</span>].</p><p>Figure 1: Boutillier et al. [<span>1</span>], Figures 2–5: istockphoto.com.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":"114 10","pages":"2419-2420"},"PeriodicalIF":2.1,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/apa.70284","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145021794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Video-Based Evaluation of Checklist Adherence on a Neonatal Intensive Care Unit: A Prospective Observational Study.","authors":"Lisa Kessler, Hannah Schwarz, Katharina Bibl, Robyn Dvorsky, Andrea Lietz, Lena Strasser, Vanessa Roth, Moritz Haderer, Katrin Klebermass-Schrehof, Tobias Werther, Angelika Berger, Michael Wagner","doi":"10.1111/apa.70288","DOIUrl":"https://doi.org/10.1111/apa.70288","url":null,"abstract":"<p><strong>Aim: </strong>Successful procedural performance in a Neonatal Intensive Care Unit (NICU) depends on skill performance and preparation. Checklists are beneficial, and video reviewing enhances adherence to guidelines. This study assessed whether video recordings can be used to assess checklist deviations, the extent to which proceduralists (doctors from 1 to ≥ 6 years of experience) deviate from checklists, and whether video recordings can help to improve existing and create new checklists.</p><p><strong>Methods: </strong>In this single-center study at the tertiary NICU of the Medical University of Vienna, Austria, fifty-one videos from six different procedures were analyzed: (i) intubation, (ii) insertion of a chest drain, (iii) insertion of an umbilical venous catheter (UVC), (iv) insertion of a central venous catheter (CVC), (v) lumbar puncture (LP), and (vi) puncture of Ommaya reservoir. Each step was scored using a 4-point scale (-1 to 2) using the corresponding checklist.</p><p><strong>Results: </strong>Twenty proceduralists performed the 51 videos. 78% of all checklist steps were assessable through video analysis. Deviations were identified in each procedure (10%-17.9%). We created two new checklists by analyzing video recordings.</p><p><strong>Conclusion: </strong>Checklist deviations occur regularly and can be detected by analyzing clinical video recordings. Video recordings are useful to revise existing and create new checklists.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Amplitude-Integrated Electroencephalography Signals, Abnormal General Movements and Later Motor Outcome in Preterm Infants.","authors":"Marlene Hammerl, Anna Posod, Maria Sappler, Christina Schreiner, Nina Gande, Vera Neubauer, Ursula Kiechl-Kohlendorfer, Elke Griesmaier","doi":"10.1111/apa.70294","DOIUrl":"https://doi.org/10.1111/apa.70294","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the relationship between amplitude-integrated electroencephalography (aEEG), general movement assessment (GMA) and later motor outcome in preterm infants.</p><p><strong>Methods: </strong>This retrospective study analysed data from 274 very preterm infants born at Innsbruck Medical University Hospital. aEEG was performed within 72 h of birth and weekly for the first month. GMA was conducted at 34, 40 and 52 weeks postmenstrual age. Motor outcome was assessed at 2 years. Statistical analyses included comparative tests, multivariate logistic regression and ROC curves.</p><p><strong>Results: </strong>Significant differences in aEEG scores were observed between infants with normal and abnormal GMs. After adjusting for neonatal characteristics, only day 1 aEEG remained significantly associated with general movements (GMs) at term and post-term. At 2 years, psychomotor outcome was significantly delayed in infants with abnormal GMA at term and post-term.</p><p><strong>Conclusions: </strong>This study underscores the importance of integrating aEEG and GMA in preterm infants. Our findings should be interpreted as a proof-of-concept, illustrating the feasibility of integrating aEEG with GMA for a comprehensive evaluation of early neurodevelopment. Future research should investigate potential synergistic effects of diagnostic tools to identify infants at risk for neurological injury and developmental delay with the aim to assess the effect of early interventions.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}