Sarah C H Thompson, Karli Treyvaud, Leona Pascoe, Rheanna M Mainzer, Thi-Nhu-Ngoc Nguyen, Terrie E Inder, Lex W Doyle, Peter J Anderson
{"title":"Trajectories of social outcomes in individuals born very preterm from childhood to adolescence.","authors":"Sarah C H Thompson, Karli Treyvaud, Leona Pascoe, Rheanna M Mainzer, Thi-Nhu-Ngoc Nguyen, Terrie E Inder, Lex W Doyle, Peter J Anderson","doi":"10.1111/apa.17434","DOIUrl":"https://doi.org/10.1111/apa.17434","url":null,"abstract":"<p><strong>Aim: </strong>To compare trajectories of social functioning in peer problems and prosocial behavior from 5 to 13 years between individuals born very preterm (VPT) and full-term (FT).</p><p><strong>Methods: </strong>Participants were from the Victorian Infant Brain Study (VIBeS) longitudinal cohort, consisting of 224 individuals born VPT and 77 born FT recruited at birth. Social functioning was measured using the parent-rated Strengths and Difficulties Questionnaire (SDQ) peer problems and prosocial behavior subscales at 5, 7, and 13 years' corrected age. Multilevel mixed effects models were fitted.</p><p><strong>Results: </strong>Peer problems increased with age (adjusted mean difference per year = 0.04, 95% confidence interval [CI] = 0.01, 0.07, p = 0.02), with higher peer problems in the VPT compared with the FT group (adjusted mean difference between groups = 0.46, 95% CI = 0.06, 0.86, p = 0.02). Prosocial behavior increased from early to middle childhood and decreased approaching adolescence, but was similar between VPT and FT groups (adjusted mean difference between groups = -0.05, 95% CI = -0.50, 0.40, p = 0.82).</p><p><strong>Conclusion: </strong>Children born VPT are at greater risk for peer problems than FT peers and may benefit from receiving greater early social support.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pauline Scherdel, Marion Taine, Manon Bergerat, Andreas Werner, Julien Le Breton, Michel Polak, Agnès Linglart, Rachel Reynaud, Bruno Frandji, Jean-Claude Carel, Raja Brauner, Martin Chalumeau, Barbara Heude
{"title":"New French height velocity growth charts: An innovative big-data approach based on routine measurements.","authors":"Pauline Scherdel, Marion Taine, Manon Bergerat, Andreas Werner, Julien Le Breton, Michel Polak, Agnès Linglart, Rachel Reynaud, Bruno Frandji, Jean-Claude Carel, Raja Brauner, Martin Chalumeau, Barbara Heude","doi":"10.1111/apa.17433","DOIUrl":"https://doi.org/10.1111/apa.17433","url":null,"abstract":"<p><strong>Aim: </strong>Height velocity is considered a key auxological tool to monitor growth, but updated height velocity growth charts are lacking. We aimed to derive new French height velocity growth charts by using a big-data approach based on routine measurements.</p><p><strong>Methods: </strong>We extracted all growth data of children aged 1 month-18 years from the electronic medical records of 42 primary care physicians, between 1 January 1990 and 8 February 2018, throughout the French metropolitan territory. We derived annual and biannual height velocity growth charts until age 15 years by using the Lambda-Mu-Sigma method. These new growth charts were compared to the 1979 French and 2009 World Health Organisation (WHO) ones.</p><p><strong>Results: </strong>New height velocity growth charts were generated with 193 124 and 209 221 annual and biannual values from 80 204 and 87 260 children, respectively, and showed good internal fit. Median curves were close to the 1979 French or 2009 WHO ones, but SD curves displayed important differences. Similar results were found with the biannual height velocity growth charts.</p><p><strong>Conclusion: </strong>We produced new height velocity growth charts until age 15 years by using a big-data approach applied to measurements routinely collected in clinical practice. These updated growth charts could help optimise growth-monitoring performance.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142309194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Niccolò Parri, Martina Giacalone, Marco Greco, Arianna Aceti, Ersilia Lucenteforte, Iuri Corsini
{"title":"Management of neonatal head injuries: A retrospective cohort study.","authors":"Niccolò Parri, Martina Giacalone, Marco Greco, Arianna Aceti, Ersilia Lucenteforte, Iuri Corsini","doi":"10.1111/apa.17420","DOIUrl":"https://doi.org/10.1111/apa.17420","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this study is to describe circumstances, management and short-term outcomes of neonatal head trauma, and adherence to the Paediatric Emergency Care Applied Research Network (PECARN) head trauma prediction rule for children under 2 years.</p><p><strong>Methods: </strong>Multicentre retrospective cohort study of neonates (<29 days) with head trauma across 25 emergency departments (ED) from January 2017 to June 2021.</p><p><strong>Results: </strong>A total of 492 neonates (median age 17 days, range 0-28 days) with non-trivial head trauma were enrolled. Falls were the most common injury mechanism (375/492, 76.2%). Imaging was performed in 150/492 (30.5%) neonates. Clinically important traumatic brain injury (ciTBI), defined as death, neurosurgery, prolonged intubation, or extended hospitalisation from injury, occurred in 7/492 (1.4%) cases. Notably, 286/492 (58.1%) neonates were managed by short-term observation (<48 h), and 126/492 (25.6%) were admitted. Among high-risk neonates per PECARN criteria, 17/21 (80.9%) did not undergo recommended head CT scans but were observed within ED short observation units or underwent alternative imaging, with no ciTBI diagnoses among those discharged without CT.</p><p><strong>Conclusion: </strong>Severe neonatal head injuries are rare, and most neonatal head injuries have a favourable outcome, making observation a suitable approach, while remaining vigilant for signs of non-accidental injuries.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christian Gadsbøll, Lars J Björklund, Mikael Norman, Thomas Abrahamsson, Magnus Domellöf, Anders Elfvin, Aijaz Farooqi, Lena Hellström-Westas, Stellan Håkansson, Karin Källén, Erik Normann, Fredrik Serenius, Karin Sävman, Petra Um-Bergström, Ulrika Ådén, David Ley
{"title":"Centralisation of extremely preterm births and decreased early postnatal mortality in Sweden, 2004-2007 versus 2014-2016.","authors":"Christian Gadsbøll, Lars J Björklund, Mikael Norman, Thomas Abrahamsson, Magnus Domellöf, Anders Elfvin, Aijaz Farooqi, Lena Hellström-Westas, Stellan Håkansson, Karin Källén, Erik Normann, Fredrik Serenius, Karin Sävman, Petra Um-Bergström, Ulrika Ådén, David Ley","doi":"10.1111/apa.17429","DOIUrl":"https://doi.org/10.1111/apa.17429","url":null,"abstract":"<p><strong>Aim: </strong>We evaluated the increased centralisation of extremely preterm (EPT) births in Sweden in relation to the changes in mortality and morbidity.</p><p><strong>Methods: </strong>Population-based data covering Swedish live births from 22 + 0 to 26 + 6 weeks of gestation during 2004-2007 and 2014-2016 were analysed for associations between time-period, birth within (inborn) or outside (outborn) regional centres, and outcomes.</p><p><strong>Results: </strong>Among 1626 liveborn infants, 703 were born in 2004-2007 and 923 in 2014-2016. Birth outside (vs. within) regional centres was associated with a higher infant mortality even after adjustment for birth cohort, gestational age, birthweight standard deviation score and infant sex (adjusted odds ratio 2.01, 95% confidence interval 1.31-3.07, p = 0.001). The higher 1-year mortality in outborn infants was mainly due to more deaths within 24 h after birth. Outborn infants had a higher incidence of intraventricular haemorrhage grade 3-4 than inborn infants (22% vs. 14% in 2004-2007, and 22% vs. 13% in 2014-2016, both p < 0.05). While survival to 1 year without major morbidity increased in inborn infants (33%-40%, p = 0.008), it remained unchanged in outborn infants (29% vs. 30%, p = 0.88).</p><p><strong>Conclusion: </strong>Centralisation of EPT births contributed to a lower 1-year mortality in 2014-2016 than that in 2004-2007, attributed to a decrease in deaths before 24 h among inborn infants.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142309193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ingrid Alvarez, Katarina Tötterman, Emma Honkaniemi, Ihsan Sarman, Karin Bäck, Lisa Forsberg, Essi Whaites Heinonen, Jenny Svedenkrans
{"title":"Breastfed infants exposed to lamotrigine faced a low risk of toxic effects","authors":"Ingrid Alvarez, Katarina Tötterman, Emma Honkaniemi, Ihsan Sarman, Karin Bäck, Lisa Forsberg, Essi Whaites Heinonen, Jenny Svedenkrans","doi":"10.1111/apa.17432","DOIUrl":"https://doi.org/10.1111/apa.17432","url":null,"abstract":"We aimed to investigate plasma lamotrigine concentrations and clinical effects in infants exposed to lamotrigine through breastfeeding.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142251864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vera Neubauer, Nina Gande, Ira Winkler, Anna Posod, Christina Schreiner, Marlene Hammerl, Ursula Kiechl-Kohlendorfer, Elke Griesmaier
{"title":"Postnatal cytomegalovirus infections did not alter amplitude-integrated electroencephalography signals or general movements in preterm infants.","authors":"Vera Neubauer, Nina Gande, Ira Winkler, Anna Posod, Christina Schreiner, Marlene Hammerl, Ursula Kiechl-Kohlendorfer, Elke Griesmaier","doi":"10.1111/apa.17430","DOIUrl":"https://doi.org/10.1111/apa.17430","url":null,"abstract":"<p><strong>Aim: </strong>Controversy prevails about whether postnatal cytomegalovirus (CMV) infections are associated with adverse neurodevelopmental outcomes. We aimed to investigate whether amplitude-integrated electroencephalography (aEEG) signals and General Movement Assessment (GMA) scores differed in very preterm infants with postnatal CMV infections.</p><p><strong>Methods: </strong>This was a retrospective single-centre study, conducted at Innsbruck Medical University Hospital, Austria, between February 2011 and November 2018. We screened 461 infants born before 32 weeks of gestation for CMV infections. Their aEEG signals were analysed for the distribution of background activity patterns and their total maturation scores and component scores. The GMA was performed at 36 weeks of postmenstrual age, term-equivalent age and 3 months of corrected age.</p><p><strong>Results: </strong>We studied 20 infants (55% male) with postnatal CMV infections, born at a mean gestational age of 28.1 (25.3-30.7) weeks and a mean birth weight of 1064 (640-1600) grams. No differences were found in the aEEG signals or GMA scores between these infants and 441 uninfected controls.</p><p><strong>Conclusion: </strong>Preterm infants with postnatal CMV infections showed no alterations in neonatal aEEG signals or GMA scores, compared with the uninfected controls. Longer follow-up studies are needed to evaluate the effect of postnatal cytomegalovirus infections on later neurodevelopmental outcomes.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Niall Conroy, David Adam Barr, Joy Nalley, Juliana Emilia Mamie Conteh, Louise Mitchell, Gerard Bury
{"title":"Electrification and specialist training associated with decreased neonatal mortality and increased admissions in Sierra Leone.","authors":"Niall Conroy, David Adam Barr, Joy Nalley, Juliana Emilia Mamie Conteh, Louise Mitchell, Gerard Bury","doi":"10.1111/apa.17431","DOIUrl":"https://doi.org/10.1111/apa.17431","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this study was to describe the evolution of a regional neonatal service in Sierra Leone and changes in mortality and service use as it transitioned from a non-specialist service to a dedicated special care baby unit (SCBU).</p><p><strong>Methods: </strong>This was a retrospective observational study. Anonymised data were taken from the ward admissions books at Bo Government Hospital, and trends in admissions and mortality within the neonatal service were examined for each stage of the department's evolution.</p><p><strong>Results: </strong>Four phases of the service's development were identified between November 2015 and October 2019. Records of 2377 admissions and 333 deaths were identified. The average number of admissions per month and deaths per month varied by service development phase. There was a trend towards reduced death rates and increased numbers of admissions as the unit evolved into a dedicated neonatal unit with a reliable electricity supply.</p><p><strong>Conclusions: </strong>The development of an adequately sized SCBU with a reliable electricity supply and specially trained staff was associated with a reduction in the death rate and an increase in admissions.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":null,"pages":null},"PeriodicalIF":2.4,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bryan J. Ranger, Allison Lombardi, Susie Kwon, Mary Loeb, Hayoung Cho, Keshi He, Donglai Wei, Jinhee Park
{"title":"Ultrasound for assessing paediatric body composition and nutritional status: Scoping review and future directions","authors":"Bryan J. Ranger, Allison Lombardi, Susie Kwon, Mary Loeb, Hayoung Cho, Keshi He, Donglai Wei, Jinhee Park","doi":"10.1111/apa.17423","DOIUrl":"https://doi.org/10.1111/apa.17423","url":null,"abstract":"This scoping review aims to assess the utility of ultrasound as a prospective tool in measuring body composition and nutritional status in the paediatric population. We provide a comprehensive summary of the existing literature, identify gaps, and propose future research directions.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142251865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna-Riitta Heikkilä, Marko Elovainio, Hanna Raaska, Helena Lapinleimu
{"title":"One-third of children had clinical signs of developmental coordination disorder 6 months after their international adoption","authors":"Anna-Riitta Heikkilä, Marko Elovainio, Hanna Raaska, Helena Lapinleimu","doi":"10.1111/apa.17428","DOIUrl":"https://doi.org/10.1111/apa.17428","url":null,"abstract":"Our aim was to fill a gap in the research about the prevalence of developmental coordination disorder (DCD) among internationally adopted children. We explored the prevalence of signs of DCD and the associations between those and behavioural problems six and 18 months after adoption.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":null,"pages":null},"PeriodicalIF":3.8,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142251893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}