Acta Paediatrica最新文献

Investigating Shared Biological and Psychosocial Mechanisms of Sleep Bruxism and Adolescents' Headaches: Insights. 研究睡眠磨牙症和青少年头痛的共同生物学和社会心理机制：见解。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-10-09 DOI: 10.1111/apa.70336

Sevim Şahin

引用次数: 0

Growth and Body Composition at Discharge in Full-Term Neonates With Congenital Anomalies. 先天性畸形足月新生儿出院时的生长和身体组成。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-10-08 DOI: 10.1111/apa.70332

Amit Trivedi, Kathryn Browning Carmo, Kristen James-Nunez, Adrienne Gordon

{"title":"Growth and Body Composition at Discharge in Full-Term Neonates With Congenital Anomalies.","authors":"Amit Trivedi, Kathryn Browning Carmo, Kristen James-Nunez, Adrienne Gordon","doi":"10.1111/apa.70332","DOIUrl":"https://doi.org/10.1111/apa.70332","url":null,"abstract":"Aims: To evaluate growth and body composition at NICU discharge in term-born neonates with structural congenital anomalies and identify predictors of body fat percentage.Methods: This prospective observational study included 61 term neonates (≥ 37 weeks' gestation) with cardiac or non-cardiac congenital anomalies requiring surgery. Anthropometric measures at birth and discharge and body composition at discharge were measured.Results: Mean z-scores declined significantly between birth and discharge for weight (-0.38 to -1.53), length (-0.02 to -0.64), and head circumference (-0.04 to -0.79) (all p < 0.001). Infants with congenital heart disease demonstrated a more pronounced weight z-score decline. At discharge, mean body fat was 9% (SD 4.9), with no significant differences between cardiac and non-cardiac anomalies or sexes. Fat-free mass was relatively preserved (91%, 910 g/kg). Multivariate analysis identified time of full enteral feeds (p = 0.02) and maternal ethnicity (p = 0.03) as independent predictors of body fat.Conclusion: Term neonates with congenital anomalies experience significant postnatal growth restriction and reduced fat mass by NICU discharge. Maternal ethnicity and time to full enteral feeds independently influence body fat percentage. These findings support the need for individualised nutrition and routine body composition monitoring to optimise outcomes in this high-risk group.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145245817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mother-Newborn Couplet Care in Denmark: A National Cross-Sectional Survey of Clinical Practices and Challenges. 丹麦母婴对联护理：临床实践和挑战的全国横断面调查。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-10-08 DOI: 10.1111/apa.70334

Joan Neergaard Larsen, Helena Hansson, Porntiva Poorisrisak, Laura Emdal Navne, Stina Klemming, Jette Led Sørensen, Ragnhild Maastrup

{"title":"Mother-Newborn Couplet Care in Denmark: A National Cross-Sectional Survey of Clinical Practices and Challenges.","authors":"Joan Neergaard Larsen, Helena Hansson, Porntiva Poorisrisak, Laura Emdal Navne, Stina Klemming, Jette Led Sørensen, Ragnhild Maastrup","doi":"10.1111/apa.70334","DOIUrl":"https://doi.org/10.1111/apa.70334","url":null,"abstract":"Aim: Although evidence supporting mother-newborn couplet care continues to grow, its clinical integration remains inconsistent due to ongoing barriers. This study aimed to describe current practices of mother-newborn couplet care in Danish obstetric and neonatal departments.Methods: A national cross-sectional survey was conducted in all Danish neonatal and obstetric departments. An online questionnaire identified organisational structures, collaboration between departments, and interprofessional education. Quantitative data were analysed descriptively, while qualitative responses were evaluated using content analysis.Results: The response rate was 91% (n = 31/34). Maternal treatment and care provided in neonatal departments were reported as \"always\" by 33% of respondents, \"often\" by 44%, and \"sometimes\" by 17%. Neonatal treatment and care provided in obstetric departments were reported as \"always\" by 22% of respondents, \"often\" by 33%, and \"sometimes\" by 28%. The clinical integration of couplet care depended on the level of medical needs for both. Key barriers included organisational and structural challenges and a lack of formalised interprofessional education.Conclusion: The findings highlight the current situation of reducing mother-newborn separation through couplet care. Most Danish departments report that mothers and newborns can often be cared for together. However, organisational and structural barriers still prevent the integration of mother-newborn couplet care.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extrasystoles on 24-h Holter Monitoring During the First Year of Life. 生命第一年24小时动态心电图监测的超心率。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-10-08 DOI: 10.1111/apa.70335

Asta Uusitalo, Päivi H Korhonen, Antti Tikkakoski, Pieta Lehtinen, Kaisa Ylänen, Tuija Poutanen

{"title":"Extrasystoles on 24-h Holter Monitoring During the First Year of Life.","authors":"Asta Uusitalo, Päivi H Korhonen, Antti Tikkakoski, Pieta Lehtinen, Kaisa Ylänen, Tuija Poutanen","doi":"10.1111/apa.70335","DOIUrl":"https://doi.org/10.1111/apa.70335","url":null,"abstract":"Aim: To assess the natural course of extrasystoles and their association with tachyarrhythmias on 24-h Holter monitoring during the first year of life.Methods: A retrospective chart review was performed among newborns referred for 24-h Holter monitoring at Tampere University Hospital from 2011 to 2017. Children with more than 1% extrasystoles on the initial Holter recording were included.Results: In total, 75 children and 290 Holter recordings were included. Forty-seven (63%) children were followed up due to atrial premature contractions (APCs) and 28 (37%) children were followed up due to ventricular premature contractions (VPCs). The amount of extrasystoles peaked during the first 14 days and decreased significantly during the first 2 months. However, in one-third of the children, extrasystoles increased between recordings. Extrasystoles disappeared during the first year among 92% of children with APCs and 78% of children with VPCs. Short supraventricular or ventricular tachycardias were found in 17 (23%) children's recordings. A higher percentage of extrasystoles was associated with tachyarrhythmias.Conclusion: The results support the prevailing understanding regarding the favourable prognosis of extrasystoles in newborns. Serial Holter monitoring may be advisable during the newborn period for infants with frequent extrasystoles, as some may be susceptible to tachyarrhythmias.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment Persistence Was High When Hormone Therapy for Gender Incongruence Included Comprehensive Diagnoses and Interdisciplinary Care During Adolescence. 当青春期性别不一致的激素治疗包括综合诊断和跨学科护理时，治疗持久性高。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-10-07 DOI: 10.1111/apa.70337

Katharina Feil, Lisa Senoner, Martin Fuchs, André Leonhardt, Elisabeth Reiser, Kathrin Sevecke, Bettina Toth

引用次数: 0

Once Allergic, Now Not: Do Children Use Delabeled Antibiotics?-A 5-Year Follow-Up Study. 曾经过敏，现在不再过敏：儿童是否使用无标签抗生素？- 5年随访研究。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-10-07 DOI: 10.1111/apa.70340

Nikolaos Kitsos, Antigoni Mavroudi, Ioanna Grivea, Dimitrios Cassimos

引用次数: 0

Aberrant Growth in 5-Year-Old Children After Antibiotics in the First Week of Life. 5岁儿童出生后第一周服用抗生素后的异常生长

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-10-07 DOI: 10.1111/apa.70322

Lisanne M van Leeuwen, Gina J van Beveren, Marieke A G Peeters, Dennis Souverein, Sjoerd Euser, Debby Bogaert, Marlies A van Houten

{"title":"Aberrant Growth in 5-Year-Old Children After Antibiotics in the First Week of Life.","authors":"Lisanne M van Leeuwen, Gina J van Beveren, Marieke A G Peeters, Dennis Souverein, Sjoerd Euser, Debby Bogaert, Marlies A van Houten","doi":"10.1111/apa.70322","DOIUrl":"https://doi.org/10.1111/apa.70322","url":null,"abstract":"Aim: We examined the relationship between early-life antibiotics, different regimens, and growth until age five years.Methods: Data from two parallel birth cohorts were analysed: 128 healthy term-born children and 147 term-born children who received antibiotics for suspected neonatal sepsis, randomised across three regimens: Amoxicillin+Cefotaxime, Augmentin+Gentamicin, Penicillin+Gentamicin. Until age five years, growth, environmental exposures, diet, and physical activity data were collected. Primary outcomes were weight-for-age, height-for-age, and weight-for-height z-scores with early-life antibiotic exposure and the regimen as determinants of interest.Results: The median antibiotic exposure duration was 3 days (interquartile range 2.4-5.5 days). Children exposed to early-life antibiotics had on average 0.26 lower weight-for-height z-scores over the first five years compared to unexposed controls (p = 0.014). Especially children treated with Augmentin+Gentamicin showed lower weight-for-height z-scores, compared to unexposed controls (coefficient = 0.36; p = 0.013). Additionally, at age five years, higher birth weight percentiles were associated with higher weight-for-age, height-for-age and weight-for-height and weekly lemonade consumption was associated with higher weight-for-age z-scores.Conclusion: Antibiotics in the first week of life are associated with lower weight-for-height up to age five years, with effects varying by treatment type. To explain these effects, further examination of antimicrobial-induced early-life microbiome perturbations and subsequent growth is needed.Trial registration: International Clinical Trial Registry Platform (https://trialsearch.who.int/): NL4882 and NL3821.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145245791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Parental Consent to a Neonatal Clinical Study: The Roles of Uncertainty, Burden of Sample Collection and Societal Expectations. 父母同意新生儿临床研究：不确定性，样本收集负担和社会期望的作用。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-10-06 DOI: 10.1111/apa.70333

Susanne Soendergaard Kappel, Gustav Riemer Jakobsen, Kija Lin Oestergaard, Anders Brunse, Dennis Sandris Nielsen, Lise Aunsholt

{"title":"Parental Consent to a Neonatal Clinical Study: The Roles of Uncertainty, Burden of Sample Collection and Societal Expectations.","authors":"Susanne Soendergaard Kappel, Gustav Riemer Jakobsen, Kija Lin Oestergaard, Anders Brunse, Dennis Sandris Nielsen, Lise Aunsholt","doi":"10.1111/apa.70333","DOIUrl":"https://doi.org/10.1111/apa.70333","url":null,"abstract":"Aim: Recruiting participants for neonatal clinical studies may be challenging because parental consent is required shortly after birth. This study aimed to explore reasons for parental decline of participation in a neonatal study.Method: This qualitative sub-study was conducted in the Capital Region of Denmark between June 2022 and April 2023. Parents of healthy term newborn infants who declined participation in the PrePhage study, a study investigating the transfer of faecal filtrate for the prevention of necrotising enterocolitis, were included. These parents were interviewed through semi-structured telephone interviews. Data were analysed using thematic analysis.Results: Ten parents (five mothers and five fathers of 10 different newborn infants) participated. All were first-time parents. Three themes were identified: the first theme, uncertainty of the unknown, captured how early parenthood influenced willingness to engage. The second theme, challenges and discomfort related to sample collection, reflected logistical burdens and discomfort associated with faecal samples. The third theme, balancing societal expectations, described the tension between the social value of research and expressed guilt for declining participation.Conclusion: Emotional, logistical and societal factors influenced parents' decision to decline participation in neonatal research. Future enrolment strategies should consider the timing of approach and aim to minimise participation burden.Trial registration: ClinicalTrials.gov identifier: NCT05272579 and NCT05272566.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Persistent Neonatal Risks in Maternal Type 1 Diabetes: A Call for Improved Maternal Care. 孕产妇1型糖尿病的持续新生儿风险：呼吁改善孕产妇保健。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-10-03 DOI: 10.1111/apa.70323

Sophia Brismar Wendel

引用次数: 0

Growth Charts: From Pen and Paper to Computerised Algorithms to Detect Aberrant Growth. 增长图表：从纸笔到计算机化算法检测异常增长。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-10-03 DOI: 10.1111/apa.70328

Petur B Juliusson, Mathieu Roelants

引用次数: 0