Acta Paediatrica最新文献_第10页

EBNEO COMMENTARY: Stoma or Intestinal Anastomosis for Necrotizing Enterocolitis. EBNEO评论：坏死性小肠结肠炎的吻合口或肠吻合。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-05-07 DOI: 10.1111/apa.70119

Caitlin Eason, S Christopher Derderian

引用次数: 0

Treatment With Inhaled Nitric Oxide and General Intelligence in Preterm Children in Two European Cohorts. 在两个欧洲队列中，吸入一氧化氮治疗早产儿的一般智力。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-05-06 DOI: 10.1111/apa.70118

Nicole Tsalacopoulos, Valérie Benhammou, Laetitia Marchand-Martin, Véronique Pierrat, Pierre-Yves Ancel, Armita Shahesmaeilinejad, Viktoria Rücker, Vincent Prevot, Konstantina Chachlaki, Christoph Härtel, Wolfgang Göpel, Juliane Spiegler

{"title":"Treatment With Inhaled Nitric Oxide and General Intelligence in Preterm Children in Two European Cohorts.","authors":"Nicole Tsalacopoulos, Valérie Benhammou, Laetitia Marchand-Martin, Véronique Pierrat, Pierre-Yves Ancel, Armita Shahesmaeilinejad, Viktoria Rücker, Vincent Prevot, Konstantina Chachlaki, Christoph Härtel, Wolfgang Göpel, Juliane Spiegler","doi":"10.1111/apa.70118","DOIUrl":"https://doi.org/10.1111/apa.70118","url":null,"abstract":"Aim: To investigate whether treatment with inhaled nitric oxide is associated with cognitive performance at age 5-6 years in preterm-born children.Methods: We analysed preterm children from two large European cohort studies, the German Neonatal Network (GNN) (N = 3606) and the French EPIPAGE-2 cohort (N = 2579) admitted to neonatal care and followed up at age 5-6 years. Both cohorts had recorded data on iNO treatment. General cognitive ability was tested with IQ tests. Classification and Regression trees analysis was used to identify prenatal, perinatal and neonatal, clinical and social-environmental predictors of IQ.Results: In both cohorts, treatment with inhaled nitric oxide was not associated with IQ at age 5-6 years. Analysis identified maternal educational level, gestational age at discharge from hospital, intraventricular haemorrhage and maternal country of birth as important factors associated with IQ scores.Conclusion: Treatment with inhaled nitric oxide was neither negatively nor positively associated with IQ at age 5-6 years. Neonatal and brain health, as well as socioeconomic factors are important for cognitive performance in early childhood.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Variability and Need for Uniformity in Paediatric Care Guidelines in Belgium: A National Survey. 变异性和需要统一的儿科护理指南在比利时：一项全国调查。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-05-05 DOI: 10.1111/apa.70105

Elise Ruysschaert, Thomas Antychin, Eline Vermeiren, Levi Hoste, Anne Rochtus, Amber Van Baelen

{"title":"Variability and Need for Uniformity in Paediatric Care Guidelines in Belgium: A National Survey.","authors":"Elise Ruysschaert, Thomas Antychin, Eline Vermeiren, Levi Hoste, Anne Rochtus, Amber Van Baelen","doi":"10.1111/apa.70105","DOIUrl":"https://doi.org/10.1111/apa.70105","url":null,"abstract":"Aim: To determine the current variability in the use of clinical care guidelines across hospitals and evaluate the potential for uniform guidelines throughout Belgium.Methods: A survey, consisting of 48 questions covering demographics, use of evidence-based medicine, and opinions on guideline standardisation, was conducted among paediatric trainees and paediatricians. Statistical analysis included paired t-tests (significance p < 0.05) and thematic analysis to explore variations in guideline use across hospitals, departments, and doctors.Results: A total of 124 participants responded, with an even distribution in years of training. Sixty-three percent were currently working at a university hospital. Common sources for guideline implementation included UpToDate (80%) and local guidelines (58%). The largest differences reported were in the choice of treatment options. Trainees generally consider university hospitals to have a higher number and more up-to-date guidelines. Experience-based medicine is more commonly practised than evidence-based medicine. Ninety percent of participants were convinced that uniform guidelines would enhance patient care, improve the quality of training, and promote evidence-based treatment.Conclusion: This national study indicates significant differences between hospitals, departments and practitioners in guidelines used. The majority of the participants support the adaptation of universal guidelines to improve both patient care and education.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oxygenation Instability and Short-Term Morbidities Among Very-Low-Birthweight Premature Infants. 极低出生体重早产儿的氧合不稳定和短期发病率。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-05-05 DOI: 10.1111/apa.70116

Viktoria Leikin Zach, Arieh Riskin, Irina Raizberg, Ori Hochwald, Gil Dinur, Michal Breuer, Fady Christopher Farah, Amir Kugelman, Liron Borenstein-Levin

{"title":"Oxygenation Instability and Short-Term Morbidities Among Very-Low-Birthweight Premature Infants.","authors":"Viktoria Leikin Zach, Arieh Riskin, Irina Raizberg, Ori Hochwald, Gil Dinur, Michal Breuer, Fady Christopher Farah, Amir Kugelman, Liron Borenstein-Levin","doi":"10.1111/apa.70116","DOIUrl":"https://doi.org/10.1111/apa.70116","url":null,"abstract":"Aim: Oxygenation instability is common among very-low-birthweight premature infants (VLBW) and is correlated with morbidities of prematurity. We aimed to study the association of oxygenation instability of VLBW premature infants during the first week of life, as documented by the SpO2 histogram, with short-term neonatal morbidities.Methods: VLBW infants requiring respiratory support were included. 24-h SpO2 histograms were documented once daily. A classification system, based on the distribution of the histogram, was used to classify the histograms into stable/unstable categories.Results: Seventy-seven infants with mean (SD) gestational age-28.5 (2.1) weeks and birth weight-1040 (243) g were included in our study. 2063 histograms were recorded. Mean (SD) length of follow-up-27.5 (20.1) days per infant. 62% of infants remained stable during the follow-up period, while 38% experienced instability. 52% entered the unstable period during the first week of life. These infants had a higher risk of bronchopulmonary dysplasia (BPD)/death after adjusting for gestational age (OR [95% CI] 17.5 [4.0, 77.2]; p < 0.001), and for a variety of demographic and clinical variables (OR [95% CI] 32.4 [2.5, 418.5]; p = 0.008).Conclusion: VLBW premature infants demonstrate a distinct instability pattern. Entry into the unstable phase during the first week of life is associated with BPD/death, making it a potential predictive tool. Hypoxemia burden during the first week of life is correlated with BPD or death, while iatrogenic hyperoxemia is not.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Systematic Review and Meta-Analysis Showed That Asymptomatic Viral Respiratory Infections Were Common Among Children Who Underwent Surgery. 系统回顾和荟萃分析显示，无症状病毒性呼吸道感染在接受手术的儿童中很常见。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-05-01 DOI: 10.1111/apa.70113

Anna-Karoliina Ojala, Ulla Koskela, Suvi Mattila, Minna Honkila, Tytti Pokka, Outi Peltoniemi, Juha-Jaakko Sinikumpu, Terhi Ruuska-Loewald

{"title":"Systematic Review and Meta-Analysis Showed That Asymptomatic Viral Respiratory Infections Were Common Among Children Who Underwent Surgery.","authors":"Anna-Karoliina Ojala, Ulla Koskela, Suvi Mattila, Minna Honkila, Tytti Pokka, Outi Peltoniemi, Juha-Jaakko Sinikumpu, Terhi Ruuska-Loewald","doi":"10.1111/apa.70113","DOIUrl":"https://doi.org/10.1111/apa.70113","url":null,"abstract":"Aim: This study investigated asymptomatic viral respiratory tract infections in children who had undergone surgery and their impact on postoperative outcomes.Methods: A systematic literature search was carried out using the PubMed and Scopus databases, from their inception to 24 May 2024, to identify papers published in English on the subject. A meta-analysis was also carried out.Results: Five studies with 2055 participants from the USA, Brazil, the Netherlands and China met the inclusion criteria. They were published from 2019 to 2023: three were prospective observational studies and two were retrospective cohort studies. Asymptomatic viral respiratory tract infections were detected in 17% of the participants. In one study, asymptomatic viral respiratory tract infections were associated with an increased risk of respiratory complications, and they were associated with an increased risk of mortality in another study. The pooled odds ratios had wide 95% confidence intervals and showed no statistically significant associations with respiratory complications, reintubation or mortality. The meta-analysis was limited by the low number and heterogeneity of the studies.Conclusion: This meta-analysis showed that asymptomatic viral respiratory tract infections were common among surgical paediatric patients. The associations between asymptomatic viral infections and postoperative complications were not conclusive, due to wide confidence intervals.Trial registration: International Prospective Register of Systematic Reviews: CRD42023412102.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144041071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of Bacterial Meningitis in Febrile Infants Aged 22-90 Days With Abnormal Urine Dipstick Results. 22-90天发热婴儿尿量异常细菌性脑膜炎的流行病学分析。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-04-29 DOI: 10.1111/apa.70114

María Suárez-Bustamante Huélamo, Jose Antonio Alonso-Cadenas, Leticia Pérez Garnica, Cristina Ibarzo Port, Elena Sánchez Arranz, Santiago Mintegi, Roberto Velasco Zúñiga, Borja Gómez

引用次数: 0

Four-Fold Increase of the Number of Children Diagnosed With Paediatric Feeding Disorder in Northern Sweden in 2012-2022. 2012-2022年，瑞典北部被诊断患有儿科喂养障碍的儿童人数增加了四倍。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-04-28 DOI: 10.1111/apa.70096

Elsa Gustavsson, Martina Kölgran, Maria Jonsson, Kajsa Lamm, Anna Chmielewska

{"title":"Four-Fold Increase of the Number of Children Diagnosed With Paediatric Feeding Disorder in Northern Sweden in 2012-2022.","authors":"Elsa Gustavsson, Martina Kölgran, Maria Jonsson, Kajsa Lamm, Anna Chmielewska","doi":"10.1111/apa.70096","DOIUrl":"https://doi.org/10.1111/apa.70096","url":null,"abstract":"Aim: The aim of this study was to investigate the annual prevalence and characteristics of Paediatric Feeding Disorder (PFD) in Västerbotten county, Sweden, during the years 2012-2022.Methods: In this retrospective study, medical records of patients attending paediatric clinics with possible feeding problems were identified by applying pre-defined diagnostic and procedure codes. Diagnostic criteria of PFD were verified. Additional data including nutritional status and enteral feeding tube placement were retrieved.Results: Annual prevalence of PFD increased from 1.2 (95% CI, 0.9-1.5) per 1000 children in 2012 to 5.0 (95% CI, 4.4-5.6) per 1000 children in 2022. In 2022, the prevalence in children < 5 years of age was 10.2 (95% CI, 8.7-12.0) per 1000. Of those, 28% had thinness grades 2 or 3 (moderate or severe thinness), and 31% were fed via nasogastric tube or gastrostomy.Conclusion: Prevalence of PFD has increased in the last decade, most notably for children under the age of five. High rates of malnutrition and enteral feeding in our study population indicate that we identified only the most severe cases of PFD. Given the rising prevalence of PFD, further research on the condition is of high priority.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Manifestations and Viral Codetections in Infants With Parechovirus A. 小儿小儿麻痹病毒A型的临床表现和病毒共检。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-04-24 DOI: 10.1111/apa.70111

Lars Høsøien Skanke, Hilde Lysvand, Sidsel Krokstad, Svein Arne Nordbø, Kari Risnes, Henrik Døllner

引用次数: 0

Very Preterm Infants Auditory Event-Related Potentials at Term Have Low Predictive Value for Cognitive Outcome. 极早产儿足月听觉事件相关电位对认知结果的预测价值较低。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-04-24 DOI: 10.1111/apa.70089

Holger Tingstedt Hövel, Eino Partanen, Ingrid Hansen Pupp, David Ley, Petra S Hüppi, Ingmar Rosén, Johanna Månsson, Minna Huotilainen, Vineta Fellman

{"title":"Very Preterm Infants Auditory Event-Related Potentials at Term Have Low Predictive Value for Cognitive Outcome.","authors":"Holger Tingstedt Hövel, Eino Partanen, Ingrid Hansen Pupp, David Ley, Petra S Hüppi, Ingmar Rosén, Johanna Månsson, Minna Huotilainen, Vineta Fellman","doi":"10.1111/apa.70089","DOIUrl":"https://doi.org/10.1111/apa.70089","url":null,"abstract":"Aim: To assess the prognostic value of auditory event-related potentials (AERPs) registered at term equivalent age in very preterm infants.Methods: Infants (26.5 ± 2.0 gestational weeks (GWs), n = 41 of 64 recruited) were enrolled prenatally between January 2005 and May 2007 at Skåne University Hospital, Lund, Sweden. AERP and mismatch responses to changes in duration or frequency in pure tones were measured at term-equivalent age using EEG. Neurocognitive outcome was assessed at 2 years of corrected age with Bayley scales of infant development. At 12 years of age, the subgroup of children born before 27 GWs (n = 18) were assessed with Wechsler Intelligence Scale for Children Fifth Edition (WISC-V).Results: Larger negative AERP amplitudes after 250 ms from stimulus onset to the standard and a negative rather than positive mismatch response to the frequency deviant were associated with higher Bayley score in univariable analysis. after adjustment for perinatal factors, only the duration mismatch response was associated with mental developmental index at 2 years of age. AERPs were not predictive of WISC-V test results at 12 years of age.Conclusion: AERPs at term in very preterm infants have a low prognostic value for short-term outcome. However, AERPs do not predict long-term outcome.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Shifting From Open Bay to Single-Family Rooms on Closeness in a NICU. 新生儿重症监护病房由开放式病房改为单人病房对亲密度的影响。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-04-23 DOI: 10.1111/apa.70108

J M Wielenga, A Pascual, K Ruhe, C Aarnoudse, A H van Kaam

{"title":"Effect of Shifting From Open Bay to Single-Family Rooms on Closeness in a NICU.","authors":"J M Wielenga, A Pascual, K Ruhe, C Aarnoudse, A H van Kaam","doi":"10.1111/apa.70108","DOIUrl":"https://doi.org/10.1111/apa.70108","url":null,"abstract":"Aim: To assess the impact of moving from open bay units (OBU) to single-family rooms (SFR) on parental closeness in the Neonatal Intensive Care Unit (NICU).Methods: This observational longitudinal cohort study was conducted between February 2021 and January 2024, during which time the setting changed from OBU to SFR with a mixed phase in between. All parent-infant dyads were eligible for inclusion. The self-reported time present in the unit, lap holding, and skin-to-skin care (SSC) were used to measure parental closeness.Results: 833 dyads of parents and infants were included (365 OBU, 140 mixed, 328 SFR phase). Parental presence increased for mothers from 210 min/day in the OBU to 420 min/day (p = 0.000) in the SFR, and for partners from 180 to 360 min/day (p < 0.001). Only for mothers, lap holding time increased from 100 min/day in the OBU to 120 min/day in the SFR phase (p = 0.046). SSC increased from 120 to 160 min/day (p = 0.002) for mothers and from 110 to 130 min/day (p = 0.004) for partners. These findings were independent of gestational age.Conclusion: Moving from an OBU to SFR setting increased parental closeness in the NICU. However, more changes are needed to meet the EFCNI and WHO recommendations.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0