Acta Paediatrica最新文献_第10页

Questioning the evolutionary adaptation hypothesis of EDARV370A in breast milk composition 质疑母乳成分中 EDARV370A 的进化适应假说。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2024-10-21 DOI: 10.1111/apa.17465

Jorge Briceño-Moya, Sergio V. Flores, Germán Manríquez

引用次数: 0

Vitamin D intake and status in children and adolescents: Comparing vegetarian, vegan, and omnivorous diets. 儿童和青少年的维生素 D 摄入量和状况：比较素食、纯素饮食和杂食饮食。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2024-10-20 DOI: 10.1111/apa.17463

Chandra Sekhar Devulapalli

{"title":"Vitamin D intake and status in children and adolescents: Comparing vegetarian, vegan, and omnivorous diets.","authors":"Chandra Sekhar Devulapalli","doi":"10.1111/apa.17463","DOIUrl":"https://doi.org/10.1111/apa.17463","url":null,"abstract":"Aim: This study aimed to evaluate papers analysing dietary intake, 25-hydroxyvitamin D (25(OH)D) concentrations and anthropometry in children on vegetarian, vegan and omnivorous diets, as research indicates all diets generally fall below recommended vitamin D intake.Methods: This mini review examined the vitamin D status of children aged 1-18 years by systematically searching PubMed, Google Scholar and Scopus databases from January 1, 2000, to December 31, 2023.Results: The review included nine studies published between 2000 and 2023. Four studies reported lower vitamin D intake in children on vegetarian and vegan diets compared to omnivores. Three studies reported lower 25(OH)D concentrations in children on vegetarian and vegan diets. Specifically, one study found lower concentrations in vegans compared to omnivores, another found lower concentrations in vegetarians and vegans not taking supplements and a third reported lower 25(OH)D concentrations in Asian children aged 3-4.5 years compared to Caucasian children. Three studies found no significant differences in 25(OH)D between diet groups. Three studies assessing anthropometry showed that vegetarians have similar body weight and height as omnivores.Conclusion: Children across all dietary groups may have low vitamin D intakes; supplementation should be considered for those with inadequate sun exposure, especially those avoiding animal products.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reference values for cerebral and peripheral tissue oximetry in children: A clinical TD-NIRS study. 儿童大脑和外周组织血氧饱和度参考值：TD-NIRS 临床研究。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2024-10-19 DOI: 10.1111/apa.17459

Valeria Calcaterra, Michele Lacerenza, Virginia Rossi, Sara Zanelli, Davide Contini, Caterina Amendola, Mauro Buttafava, Alessandro Torricelli, Gianvincenzo Zuccotti

{"title":"Reference values for cerebral and peripheral tissue oximetry in children: A clinical TD-NIRS study.","authors":"Valeria Calcaterra, Michele Lacerenza, Virginia Rossi, Sara Zanelli, Davide Contini, Caterina Amendola, Mauro Buttafava, Alessandro Torricelli, Gianvincenzo Zuccotti","doi":"10.1111/apa.17459","DOIUrl":"https://doi.org/10.1111/apa.17459","url":null,"abstract":"Aim: Current non-invasive near-infrared spectroscopy (NIRS) tissue oximetry suffers from suboptimal reproducibility over probe repositioning, hindering clinical threshold establishment. Time Domain-NIRS (TD-NIRS) offers higher precision but lacks sufficient paediatric data, preventing effective clinical application. We aimed to establish reference ranges for cerebral and mid-upper arm (MUA) tissue haemodynamics in paediatric subjects using TD-NIRS and explore correlations with auxological variables.Methods: TD-NIRS measurements were conducted acquiring data from cerebral and MUA regions with the NIRSBOX tissue oximeter. Morphological and clinically relevant information were collected to explore potential correlations with TD-NIRS derived parameters.Results: TD-NIRS assessment was applied in 350 children (8.4 ± 5.0 years). Precision of TD-NIRS was demonstrated with standard deviations of 0.9% (StO2) and 4.2 μM (tHb) for frontotemporal cerebral cortex, and 0.8% (StO2) and 3.7 μM (tHb) for MUA. No user dependency was observed. The trends of values for cerebral and peripheral regions vary differently according to age and auxological parameters.Conclusion: This study reports resting-state optical and haemodynamic values for a healthy paediatric population, providing a foundation for future investigations into clinically relevant deviations in these parameters. Furthermore, correlations with anthropometric and demographic values provide valuable insights for a deeper understanding of tissue haemodynamic evolution in childhood.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insulin resistance and glucose metabolism abnormalities in children with juvenile idiopathic arthritis. 幼年特发性关节炎患儿的胰岛素抵抗和糖代谢异常。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2024-10-19 DOI: 10.1111/apa.17464

Anna Di Sessa, Marica Esposito, Margherita Luciano, Emanuele Miraglia Del Giudice, Alma Nunzia Olivieri, Maria Francesca Gicchino

引用次数: 0

Most babies born at a French hospital before 26 weeks survived with good outcomes. 在法国的一家医院，大多数在 26 周前出生的婴儿都能存活下来，并取得了良好的结果。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2024-10-17 DOI: 10.1111/apa.17461

Heloise Abello, Marine Vincent, Pierre Pradat, Blandine Pastor-Diez, Stephane Hays, Jean-Charles Picaud

{"title":"Most babies born at a French hospital before 26 weeks survived with good outcomes.","authors":"Heloise Abello, Marine Vincent, Pierre Pradat, Blandine Pastor-Diez, Stephane Hays, Jean-Charles Picaud","doi":"10.1111/apa.17461","DOIUrl":"https://doi.org/10.1111/apa.17461","url":null,"abstract":"Aim: The aim of this French study was to determine the neonatal morbidity, mortality and neurodevelopmental outcomes when infants born at the limit of viability reached 2 years of corrected age. We then compared the results with national and international cohorts.Methods: This study focused on 294 French infants born from 22 to 25 weeks of gestation in a single tertiary perinatal centre from January 2010 to December 2019. We used data on neonatal mortality and morbidity to calculate the survival rates of infants without moderate to severe neurodevelopmental and sensory deficits at 2 years of corrected age. These outcomes were compared with data from contemporary epidemiological studies of similar populations.Results: Nearly two-thirds (60.5%) of the infants survived to discharge, with varying rates based on their gestational ages, and 57.3% had no severe neonatal morbidity. The vast majority (90.4%) of the 166 alive and available at 2 years of corrected age were free of moderate to severe neurodevelopmental impairment. Our survival rates exceeded a national French cohort study, but were closely aligned with international cohorts.Conclusion: These findings highlight the importance of incorporating local data into ethical decision-making about life-saving treatment for infants at the limit of viability.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Understanding host's response to staphylococcal scalded skin syndrome. 了解宿主对葡萄球菌烫伤皮肤综合征的反应。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2024-10-16 DOI: 10.1111/apa.17462

Glykeria Rouva, Eleni Vergadi, Konstantinos Krasagakis, Emmanouil Galanakis

引用次数: 0

Low-carbohydrate diet proved effective and safe for youths with type 1 diabetes: A randomised trial. 低碳水化合物饮食对 1 型糖尿病青少年有效且安全：随机试验

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2024-10-16 DOI: 10.1111/apa.17455

Neriya Levran, Noah Levek, Noah Gruber, Arnon Afek, Efrat Monsonego-Ornan, Orit Pinhas-Hamiel

{"title":"Low-carbohydrate diet proved effective and safe for youths with type 1 diabetes: A randomised trial.","authors":"Neriya Levran, Noah Levek, Noah Gruber, Arnon Afek, Efrat Monsonego-Ornan, Orit Pinhas-Hamiel","doi":"10.1111/apa.17455","DOIUrl":"https://doi.org/10.1111/apa.17455","url":null,"abstract":"Aim: Low-carbohydrate (LC) diets have gained popularity. We compared glycaemic and metabolic parameters following an LC versus a Mediterranean (MED) diet in adolescents and youths with type 1 diabetes.Methods: In a six-month, open-label, randomised trial, 40 individuals were assigned to either diet. Glycaemic outcomes, based on continuous glucose monitoring, included per cent time of blood glucose in the range [3.9-10.0 mmol/L (70-180 mg/dL)] and haemoglobin A1c (HbA1c).Results: Twenty-eight (70%) were females. The median age was 18 years. After 6 months, the median time in range increased from 47% to 58% in the LC and from 52% to 64% in the MED diet group (p = 0.98). The delta values for the time in range were 16% and 7% for the respective groups (p = 0.09). The percentage of time >13.9 mmol/L (>250 mg/dL) improved more in the LC diet than in the MED diet group: -10% vs. -2% (p = 0.005). The percentage of time <3.0 mmol/L (<54 mg/dL) was comparable. The delta HbA1c improved in both groups: -0.7% vs. -0.1% (p = 0.02). Changes in BMI Z-score and lipid levels were similar.Conclusion: Both diets improved glycaemic outcomes in adolescents and youths with type 1 diabetes, without increasing hypoglycaemia or cardiovascular risk factors, indicating comparable safety and efficacy.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Associations between birth characteristics, pubertal timing and adult height. 出生特征、青春期时间和成年身高之间的关系。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2024-10-14 DOI: 10.1111/apa.17460

Carin Skogastierna, Nazli Kalay, Diana Swolin-Eide, Anton Holmgren

{"title":"Associations between birth characteristics, pubertal timing and adult height.","authors":"Carin Skogastierna, Nazli Kalay, Diana Swolin-Eide, Anton Holmgren","doi":"10.1111/apa.17460","DOIUrl":"https://doi.org/10.1111/apa.17460","url":null,"abstract":"Aim: This study investigated the association between gestational age and birth size with pubertal timing, measured as peak height velocity, and adult height.Methods: This retrospective, population-based study was conducted in Sweden in 2023. A sub-group of the 1974 and 1990 GrowUp Gothenburg cohorts was used (n = 4700, 50% males). The subgroup consisted of healthy individuals with Nordic ethnicity, known parental heights and measured adult heights. Data on birth characteristics (gestational age, birth length, birth weight) were collected. Pubertal timing was assessed as age at peak height velocity. Univariable linear regression analysis and bivariate correlations were conducted to answer the research questions.Results: Gestational age was not associated with age at peak height velocity or adult height. Birth length and weight could explain 12% and 8% (p ≤ 0.001) respectively of attained adult height. However, birth length and birth weight could only explain the variation in age at peak height velocity to a small degree.Conclusion: This study showed that gestational age is not associated with age at peak height velocity or adult height. A positive relationship was found between birth size, particularly birth length, and adult height. No strong associations were found between birth size and age at peak height velocity.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Markers of consciousness in infants: Towards a 'cluster-based' approach. 婴儿的意识标记：基于 "群集 "的方法。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2024-10-14 DOI: 10.1111/apa.17449

Joel Frohlich, Tim Bayne

{"title":"Markers of consciousness in infants: Towards a 'cluster-based' approach.","authors":"Joel Frohlich, Tim Bayne","doi":"10.1111/apa.17449","DOIUrl":"https://doi.org/10.1111/apa.17449","url":null,"abstract":"As recently as the 1980s, it was not uncommon for paediatric surgeons to operate on infants without anaesthesia. Today, the same omission would be considered criminal malpractice, and there is an increased concern with the possibility of consciousness in the earliest stage of human infancy. This concern reflects a more general trend that has characterised science since the early 1990s of taking consciousness seriously. While this attitude shift has opened minds towards the possibility that our earliest experiences predate our first memories, convincing demonstrations of infant consciousness remain challenging given that infants cannot report on their experiences. Furthermore, while many behavioural and neural markers of consciousness that do not rely on language have been validated in adults, no one specific marker can be confidently translated to infancy. For this reason, we have proposed the 'cluster-based' approach, in which a consensus of evidence across many markers, all pointing towards the same developmental period, could be used to argue convincingly for the presence of consciousness. CONCLUSION: We review the most promising markers for early consciousness, arguing that consciousness is likely to be in place by 5 months of age if not earlier.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early identification and communication in cerebral palsy: Navigating a collaborative approach for neonatal follow-up programmes. 脑瘫的早期识别和沟通：为新生儿跟踪计划的合作方法导航。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2024-10-14 DOI: 10.1111/apa.17458

Paige Terrien Church, Rudaina Banihani, Karen Thomas, Maureen Luther, Brenda Agnew, Amber Makino, Sophie Lam-Damji, Darcy Fehlings

{"title":"Early identification and communication in cerebral palsy: Navigating a collaborative approach for neonatal follow-up programmes.","authors":"Paige Terrien Church, Rudaina Banihani, Karen Thomas, Maureen Luther, Brenda Agnew, Amber Makino, Sophie Lam-Damji, Darcy Fehlings","doi":"10.1111/apa.17458","DOIUrl":"https://doi.org/10.1111/apa.17458","url":null,"abstract":"Aim: This article will provide a clinical case demonstrating the implementation of early identification and review the tools and findings and the diagnostic approach. We will review highlighted literature on the subject of communicating a diagnosis. While improved function is a critical goal, the process of communicating the diagnosis of CP can be challenging for both parents and providers. It aims to provide insights on the evidence supporting early identification and discusses strategies for effective communication of crucial information.Methods: The article reviews the literature on communication of a diagnosis.Results: Thirteen articles were identified relating to the communication of a diagnosis of CP and parent experience. We examine this evidence, leveraging the knowledge of an interdisciplinary team and incorporating feedback from parents.Conclusion: Strategies for effective communication include engagement with families, community therapy teams and all medical providers. Consistent, individualised, collaborative communication is critical. Awareness of ableism and use of balanced, value-neutral terminology is recommended.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0