Acta PaediatricaPub Date : 2026-10-01Epub Date: 2026-06-11DOI: 10.1111/apa.70651
Fortunato Pititto, Maricla Marrone, Roberto Bellacicco, Elisa Paladini, Giuseppe Pulin
{"title":"Sudden Unexpected Death in Infancy: Two European Models, One Diagnostic Imperative.","authors":"Fortunato Pititto, Maricla Marrone, Roberto Bellacicco, Elisa Paladini, Giuseppe Pulin","doi":"10.1111/apa.70651","DOIUrl":"10.1111/apa.70651","url":null,"abstract":"","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":"2345-2346"},"PeriodicalIF":1.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13552585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148229193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to 'Sudden Unexpected Death in Infancy: Two European Models, One Diagnostic Imperative'.","authors":"Mathilde Ducloyer, Pauline Scherdel, Christèle Gras-Le Guen","doi":"10.1111/apa.70653","DOIUrl":"10.1111/apa.70653","url":null,"abstract":"","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":"2347-2348"},"PeriodicalIF":1.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13552600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148260747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta PaediatricaPub Date : 2026-10-01Epub Date: 2026-06-25DOI: 10.1111/apa.70656
Roosa Moilanen, Eero Pohjola, Laura Huilaja, Jari Jokelainen, Suvi-Päivikki Sinikumpu
{"title":"Sex-Specific Differences in Perinatal Risk Factors for Atopic Dermatitis: A Large Retrospective Population-Based Cohort Study.","authors":"Roosa Moilanen, Eero Pohjola, Laura Huilaja, Jari Jokelainen, Suvi-Päivikki Sinikumpu","doi":"10.1111/apa.70656","DOIUrl":"10.1111/apa.70656","url":null,"abstract":"<p><strong>Aim: </strong>This study was designed to determine whether gestational age at birth, the method of delivery, or birth weight were associated with the risk of developing atopic dermatitis (AD), and whether the association of risk factors differed between the sexes.</p><p><strong>Methods: </strong>A large population-based Northern Finland Birth Cohort 1986 Study that has been followed since birth. The dataset consisted of 8993 subjects who were divided into two groups based on presence or absence of AD.</p><p><strong>Results: </strong>The prevalence of AD was 23.7%. The probability of later AD was unaffected by either method of delivery or gestational age at birth. However, low birth weight compared to normal birth weight was a protective factor against AD, albeit only in men (adjusted risk ratio RR 0.54 [95% CI 0.30-0.97]). No such effect was observed in women.</p><p><strong>Conclusions: </strong>These findings suggest the existence of sex-specific risk factors for AD.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":"2299-2304"},"PeriodicalIF":1.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13552582/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148320602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adolescents' Experiences of Weight-Related Bullying in the School Setting-A Qualitative Study.","authors":"Emelie Andersson, Nicole Mpatsiaris Riboe, Kajsa Järvholm","doi":"10.1111/apa.70652","DOIUrl":"10.1111/apa.70652","url":null,"abstract":"<p><strong>Aim: </strong>Obesity is a stigmatised disease, and weight-related bullying is the most common form of victimisation. This study aimed to provide a nuanced understanding of adolescents' experiences of such victimisation and related interventions.</p><p><strong>Methods: </strong>Data were collected between April and October 2025 through semi-structured interviews and analysed using reflexive thematic analysis. Participants were Swedish adolescents aged 12-19 years, primarily recruited from obesity units.</p><p><strong>Results: </strong>The analysis generated three main themes. My body is the problem reflects how weight-related bullying is experienced in everyday contexts and how adolescents encounter pervasive messages devaluing their bodies and self-worth. When the school turns a blind eye illustrates how the school fails to protect and at times becomes part of the problem. I'm ruined for life captures how bullying erodes trust, self-confidence, and optimism about the future.</p><p><strong>Conclusion: </strong>Adolescents report that weight-related bullying has substantial negative effects on both their current and future well-being. They also perceive that schools do not take such bullying seriously enough. Healthcare providers should routinely assess whether adolescents with obesity experience weight-related bullying and respond appropriately. Schools must recognise weight-related bullying as a pervasive issue and implement strategies that do not place responsibility on the victim.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":"2269-2277"},"PeriodicalIF":1.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13552581/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148254629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta PaediatricaPub Date : 2026-10-01Epub Date: 2026-06-21DOI: 10.1111/apa.70648
Ana Morillo Palomo, Ana Riverola de Veciana, Montserrat Esquerda Aresté, Francisco José Cambra Lasaosa
{"title":"Parents Value Shared Decision-Making and Sensitive Communication During End-of-Life Care in Neonatal Intensive Care: An Exploratory Study.","authors":"Ana Morillo Palomo, Ana Riverola de Veciana, Montserrat Esquerda Aresté, Francisco José Cambra Lasaosa","doi":"10.1111/apa.70648","DOIUrl":"10.1111/apa.70648","url":null,"abstract":"<p><strong>Aim: </strong>To explore parents' needs during end-of-life decision-making and to understand their experiences in a neonatal intensive care unit (NICU) following the death of their child.</p><p><strong>Methods: </strong>This observational, retrospective study was conducted in the NICU of a tertiary-level hospital. Data were collected using a structured questionnaire administered to parents following the death of their neonate. Three main domains were explored: information and communication, the decision-making process and comfort-focused care.</p><p><strong>Results: </strong>During the study period, 51 neonates died after treatment was redirected towards comfort-focused care. Of the 102 eligible parents, 52 participated. Information and communication were highly rated (mean 6.5/7), particularly the sensitive delivery of information. Parents generally felt supported during decision-making (mean 5.6/7), and most (76.9%) preferred professional guidance. However, only half perceived concordance between their preferences and the final decision. Comfort-focused care was also positively evaluated (mean 6.13/7), although opportunities to choose the place of death were limited. The questionnaire demonstrated acceptable internal consistency (α = 0.72).</p><p><strong>Conclusion: </strong>Parents value shared decision-making that respects their values while providing professional guidance. These findings highlight the importance of sensitive communication, adequate time for reflection, ongoing support throughout the decision-making process, and meaningful opportunities to say goodbye.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":"2252-2260"},"PeriodicalIF":1.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13552593/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148297407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta PaediatricaPub Date : 2026-10-01Epub Date: 2026-06-09DOI: 10.1111/apa.70643
Knut Øymar, Joel Selvakumar, Maren Våland Øymar, Ingvild Dalen, Ken Erik Klaseie, Ujinthini Sivanantham, Kasper Øvsthus, Inger Heimdal, Kari Holte, Kari Risnes, Ketil Størdal, Claus Klingenberg
{"title":"High-Flow Nasal Cannula and Continuous Positive Airway Pressure in Infants With Acute Bronchiolitis-Trends of Use in Norway.","authors":"Knut Øymar, Joel Selvakumar, Maren Våland Øymar, Ingvild Dalen, Ken Erik Klaseie, Ujinthini Sivanantham, Kasper Øvsthus, Inger Heimdal, Kari Holte, Kari Risnes, Ketil Størdal, Claus Klingenberg","doi":"10.1111/apa.70643","DOIUrl":"10.1111/apa.70643","url":null,"abstract":"<p><strong>Aim: </strong>High-flow nasal cannula (HFNC) and continuous positive airway pressure (CPAP) are options for respiratory support in infants with bronchiolitis. The aim of this study was to evaluate the use of HFNC and CPAP in infants with bronchiolitis at five hospitals in Norway to study time trends over seasons and differences in use between hospitals.</p><p><strong>Methods: </strong>In this multicentre retrospective study, we compared data from 1186 infants < 12 months of age hospitalized for bronchiolitis at five Norwegian hospitals during the winter seasons 2017-2018, 2018-2019, and 2021-2022.</p><p><strong>Results: </strong>Over the three seasons, HFNC was provided to 29%-33% and CPAP to 8%-18% of all infants, but with a substantial difference between hospitals for both modalities. The change between seasons was less prominent but also differed between hospitals. The length of stay was longer, and the age and weight were lower in those receiving any non-invasive respiratory support, but this did not differ between infants treated with HFNC or CPAP.</p><p><strong>Conclusion: </strong>In Norwegian hospitals there was a substantial variation in the use of HFNC and CPAP for infants with bronchiolitis. This calls for unified and evidence-based guidelines for the use of non-invasive respiratory support for this patient group.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":"2244-2251"},"PeriodicalIF":1.8,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13552601/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148206383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Developmental Osteopenia: An Explanation for Fractures in Young Infants.","authors":"Chris Brook, Julie Mack, Waney Squier","doi":"10.1111/apa.70778","DOIUrl":"https://doi.org/10.1111/apa.70778","url":null,"abstract":"<p><strong>Aim: </strong>The aim is to test whether a fraction of full-term infants pass through a phase of postnatal fracture susceptibility and whether this physiological phase explains real-world fracture age distributions in young infants.</p><p><strong>Methods: </strong>Preterm infant data were used to establish fracture risk zones based on bone quality (using Speed of Sound, SOS) and metabolic activity (Alkaline Phosphatase, ALP) levels. These reference thresholds were applied to a full-term cohort to identify clinical overlap. Age distributions of full-term infants within risk zones were evaluated alongside paediatric fracture data from the KID Inpatient Database and data concerning rib fractures from cardiopulmonary resuscitation (CPR).</p><p><strong>Results: </strong>The low-SOS and high-ALP tails of the full-term population overlap with risk zones for metabolic bone disease of prematurity (MBDP) during the post-birth trough in bone mineralisation. The log-normal age distributions of full-term infants in these risk zones are indicative of a developmental phase and share the morphology and peak timing of infant rib and multiple fractures, whether registered as abuse, accidental, or CPR-related.</p><p><strong>Conclusion: </strong>The synchronisation of fracture peaks with the physiological trough of infant bone quality supports Developmental Osteopenia as an explanatory framework for rib and multiple fractures in young infancy.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paola Di Filippo, Annamaria Porreca, Duilio Petrongari, Massimiliano Raso, Benedetta Ciccone, Sabrina Di Pillo, Francesco Chiarelli, Marina Attanasi
{"title":"Impulse Oscillometry Detected Physiological Abnormalities More Frequently Than Spirometry in Children With Largely Preserved Lung Function.","authors":"Paola Di Filippo, Annamaria Porreca, Duilio Petrongari, Massimiliano Raso, Benedetta Ciccone, Sabrina Di Pillo, Francesco Chiarelli, Marina Attanasi","doi":"10.1111/apa.70763","DOIUrl":"https://doi.org/10.1111/apa.70763","url":null,"abstract":"<p><strong>Aim: </strong>We compared how well impulse oscillometry (IOS) and spirometry detected small airway dysfunction (SAD) in children with asthma and evaluated associations between IOS abnormalities, asthma control, and asthma severity.</p><p><strong>Methods: </strong>This observational study comprised 106 children aged 6-18 years with asthma who underwent IOS and spirometry before and after bronchodilator administration. We assessed SAD, bronchodilator responsiveness, asthma control using the Global Initiative for Asthma criteria and asthma severity using the Composite Asthma Severity Index.</p><p><strong>Results: </strong>Most children had mild asthma and preserved spirometry. Spirometry and IOS identified abnormalities suggestive of SAD in 10.4% and 37.7% of patients, respectively, and bronchodilator responsiveness in 12.3% and 20.8%, respectively. IOS abnormalities were not associated with asthma control, while only weak associations were observed between selected IOS parameters and asthma severity. Correlations between oscillometric and spirometric indices were significant but weak.</p><p><strong>Conclusion: </strong>IOS detected physiological abnormalities more frequently than spirometry in children with largely preserved lung function. However, these additional abnormalities were not associated with current asthma control and only showed weak associations with asthma severity. IOS should be considered a complementary physiological assessment. Longitudinal studies are needed to establish the clinical relevance and prognostic significance of these findings.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring the Feasibility and Acceptability of Compassion and Mindfulness Training for Adolescents With Type 1 Diabetes and Their Caregivers.","authors":"Emilie Bundgaard Lindkvist, Steffen U Thorsen, Cecilie Paulsrud, Stine Møller Sildorf, Annette Korsholm Mouritsen, Lone Fjorback, Nanja Holland Hansen, Jannet Svensson","doi":"10.1111/apa.70777","DOIUrl":"https://doi.org/10.1111/apa.70777","url":null,"abstract":"<p><strong>Aim: </strong>To examine the feasibility and acceptability of mindfulness training for adolescents with Type 1 diabetes (T1D) and compassion training for caregivers.</p><p><strong>Methods: </strong>Adolescents aged 12-17 years with T1D, and their caregivers were recruited from two diabetes centres between 2022 and 2023 to participate in an eight-week, online, open-label course (Mindfulness training for adolescents; compassion training for parents). Patient-reported outcomes, glycaemic outcomes and stress measures were collected during pre-specified in-clinic visits. The changes over the course of the study were assessed descriptively.</p><p><strong>Results: </strong>Thirteen adolescents (age 13.6 ± 1.2 years; 62% female) and 30 caregivers (age 46.8 ± 4.7 years; 65% female; 83% with medium- or long-term education) were enrolled; nine adolescents and 21 parents completed this feasibility study. Interventions were delivered in two rounds. After introducing a face-to-face pre-meeting before the second round, adherence and retention improved, particularly among adolescents. Completers reported positive experiences and showed improvements in diabetes distress (PAID) and well-being (WHO-5). Qualitative findings suggested that increased parental calmness and kindness reduced parent-adolescent conflicts, and parents valued peer support and community.</p><p><strong>Conclusion: </strong>Compassion and mindfulness training appear feasible and may support mental well-being in families with T1D; however, broader reach requires integration into routine clinical care.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Berezin Shoham, Revital Perlov Gavze, Liat Lev-Shalem, Arnon Elizur, Amir Ben Tov, Naama Epstein-Rigbi
{"title":"Food Allergies Are Associated With a Substantially Higher Burden of Atopic Comorbidities and Increased Healthcare Use.","authors":"Anna Berezin Shoham, Revital Perlov Gavze, Liat Lev-Shalem, Arnon Elizur, Amir Ben Tov, Naama Epstein-Rigbi","doi":"10.1111/apa.70764","DOIUrl":"https://doi.org/10.1111/apa.70764","url":null,"abstract":"<p><strong>Aim: </strong>We assessed the prevalence of atopic comorbidities and healthcare service use among children with food allergies.</p><p><strong>Methods: </strong>This retrospective matched cohort study used data from a large health maintenance organisation, which insures and provides universal healthcare services. Children aged 0-18 years who were diagnosed with food allergies from 2001 to 2019 were matched 1:1 with non-allergic controls. Data on demographics, rate of comorbidities, and healthcare use were compared. Adjusted odds ratios (aOR) and confidence intervals (CI) were calculated.</p><p><strong>Results: </strong>We identified 20 418 children with food allergies and matched them to 20 418 controls. Cases had significantly higher rates of allergic comorbidities, including allergic rhinitis (aOR 2.09, 95% CI 1.95-2.25), atopic dermatitis (aOR 2.04, 95% CI 1.94-2.14), and eosinophilic esophagitis (aOR 15.4, 95% CI 6.04-39.55; 104 vs. 5 events). Most prescription rates were markedly elevated, particularly for hydrolysed formulas (aOR 12.32, 95% CI 10.83-14.0). Specialist consultations were more frequent, with the greatest increases in gastroenterology (aOR 2.23, 95% CI 2.09-2.37) and pulmonology (aOR 2.03, 95% CI 1.90-2.17). General healthcare use was higher, including emergency department visits and hospitalisations.</p><p><strong>Conclusion: </strong>Paediatric food allergies were associated with a substantially higher burden of atopic comorbidities and increased healthcare use in this large national cohort.</p>","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149066126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}