Acta Paediatrica最新文献_第9页

Comment on: "Long-Term Outcome of Paediatric Crohn's Disease Patients With Deep Ulcerations at Diagnosis". 评论：“诊断时伴有深部溃疡的儿科克罗恩病患者的长期预后”。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-06-11 DOI: 10.1111/apa.70177

Renu Sah, Ankita Mathur

引用次数: 0

Rapid Influenza Diagnosis in Children With Serious Bacterial Infection-Like Symptoms. 儿童严重细菌感染样症状的快速流感诊断

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-06-10 DOI: 10.1111/apa.70174

Melanie Forster, Alexandra Tielli, Anne-Aurelie Lopes

{"title":"Rapid Influenza Diagnosis in Children With Serious Bacterial Infection-Like Symptoms.","authors":"Melanie Forster, Alexandra Tielli, Anne-Aurelie Lopes","doi":"10.1111/apa.70174","DOIUrl":"https://doi.org/10.1111/apa.70174","url":null,"abstract":"Aim: To evaluate the impact of the influenza diagnosis by the Quidel Sofia rapid influenza fluorescent immunoassay (FIA) on children presenting with serious bacterial infection (SBI)-like symptoms in an emergency department (ED).Methods: A cohort study was conducted on 161 children with SBI-like symptoms, who underwent a Quidel Sofia test. The management of Influenza-positive and Influenza-negative children was compared on diagnostic tests, antibiotic use, and hospitalisation rates. Follow-up was performed 7-10 days post-discharge to confirm SBI non-omission.Results: Influenza-positive children underwent fewer diagnostic tests, including fewer invasive tests, than influenza-negative children (58.1% vs. 90.7%, p < 0.001 and 47.7% vs. 72%, p = 0.002, respectively), received fewer antibiotics (10.5% vs. 33.3%, p < 0.001), had lower hospitalisation rates (20.9% vs. 40%, p = 0.008) and shorter ED visits (133 [52-257] minutes vs. 177 [92-273] minutes, p = 0.002). No influenza-positive patient had a missed SBI, even among the youngest patients. One developed a secondary SBI 4 days later resulting in death.Conclusion: This study demonstrated the benefit of the influenza diagnosis by Quidel Sofia rapid influenza FIA in medical management without omitting SBI in children with SBI-like symptoms. Therefore, the Quidel Sofia test can help alleviate ED overcrowding during the influenza season while maintaining vigilance for bacterial co-infection.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study on Hospital Formularies in Afghanistan Highlights the Challenges in Paediatric Pharmacotherapy. 阿富汗医院处方研究凸显儿科药物治疗面临的挑战。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-06-10 DOI: 10.1111/apa.70176

Amina Ahmady

引用次数: 0

The Role of Social Paediatrics in the 21st Century: The Yield of 50 Years of Social Paediatrics in the Netherlands. 21世纪社会儿科的角色：荷兰50年社会儿科的成果。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-06-10 DOI: 10.1111/apa.70165

E M van de Putte, E E Berkelbach van der Sprenkel, S L Nijhof

引用次数: 0

Diagnosing Dysfunctional Breathing Using the Nijmegen Questionnaire or Visual Assessment of Breathing Pattern. 使用奈梅亨问卷或呼吸模式视觉评估诊断呼吸功能障碍。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-06-09 DOI: 10.1111/apa.70163

Femke B Postma, Imke K de Boer, Michelle Laarman Eikelboom, Lidy van Lente, Arvid W A Kamps

引用次数: 0

Issue Highlights 问题突出

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-06-09 DOI: 10.1111/apa.70139

Anna Käll, Hugo Lagercrantz

引用次数: 0

The Characteristics of Isolated Duodenal Bulb Coeliac Disease in Children: A Multicentre Retrospective Study. 儿童孤立性十二指肠球状乳糜泻的特点：一项多中心回顾性研究。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-06-07 DOI: 10.1111/apa.70169

Eyal Zifman, Jenni Berliand, Bar Sofer, Michal Kori, Firas Rinawi

{"title":"The Characteristics of Isolated Duodenal Bulb Coeliac Disease in Children: A Multicentre Retrospective Study.","authors":"Eyal Zifman, Jenni Berliand, Bar Sofer, Michal Kori, Firas Rinawi","doi":"10.1111/apa.70169","DOIUrl":"https://doi.org/10.1111/apa.70169","url":null,"abstract":"Aim: A minority of patients with coeliac disease have mucosal pathology limited to the duodenal bulb. We aimed to describe the baseline characteristics of isolated duodenal bulb coeliac disease in children.Methods: In this retrospective multicentre study of paediatric patients diagnosed with coeliac disease, based on biopsies obtained separately from the duodenal bulb and distal duodenum, we evaluated the demographic, anthropometric, clinical, associated diseases and coeliac serology characteristics of the patients.Results: Among the 586 children diagnosed with coeliac disease, 459 (78%) were classified as classic and 127 (22%) as isolated duodenal bulb coeliac disease-376 (64.2%) were female and the median age was 7 years (IQR 5-11). In multivariate logistic regression, scalloping of the duodenum (55.1% vs. 17.3%, p < 0.001, OR 4.7, 95% CI 2.8-8), growth impairment (9.8% vs. 9.4%, p = 0.012, OR 2.7, 95% CI 1.4-5.5) and baseline anti-tissue transglutaminase levels > 10 upper limit of norm (71.5% vs. 29.9%, p < 0.001, OR 4.5, 95% CI 2.8-7.2) were associated with a higher probability of having classic coeliac disease.Conclusions: Lack of growth impairment, anti-tissue transglutaminase levels > 10 upper limit of norm and duodenal scalloping are predictive of isolated duodenal bulb involvement, making duodenal bulb biopsies even more important during esophagogastroduodenoscopy for the diagnosis of coeliac disease.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pre-Pandemic Prevalence of Post COVID-19 Condition Symptoms in Adolescents. 青少年COVID-19后症状大流行前的流行情况

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-06-06 DOI: 10.1111/apa.70123

Jesse Linton, Joshua Carmichael, Fiona Newlands, Amal Puri, Lana Fox-Smith, Snehal M Pinto Pereira, Anna Coughtrey, Roz Shafran, Terence Stephenson

{"title":"Pre-Pandemic Prevalence of Post COVID-19 Condition Symptoms in Adolescents.","authors":"Jesse Linton, Joshua Carmichael, Fiona Newlands, Amal Puri, Lana Fox-Smith, Snehal M Pinto Pereira, Anna Coughtrey, Roz Shafran, Terence Stephenson","doi":"10.1111/apa.70123","DOIUrl":"https://doi.org/10.1111/apa.70123","url":null,"abstract":"Aim: The emergence of post COVID-19 condition (PCC) within adolescents has been characterised by a wide range of symptoms, raising concerns for young people's health and quality of life. However, many symptoms are non-specific and there is considerable variation in symptom reporting. It is essential to understand how rates of these symptoms compare to the pre-pandemic health of adolescents.Methods: A systematic search of academic literature and websites, using traditional and automated search systems, was undertaken to identify symptoms described in adolescents aged 10-19 years in the 30 years up to and including 2019. Studies were reviewed and symptom prevalence data extracted.Results: Twenty-five sources (n = 483 097 participants) met the inclusion criteria, including longitudinal and cross-sectional study designs. The description and prevalence of symptoms varied widely, but there was a high pre-pandemic median prevalence of cough (13.6%), headache (30.0%), and fatigue (20.5%). These high prevalences highlight a gap in understanding of pre-pandemic adolescent health and the need for comprehensive, serial symptom profiling.Conclusion: These findings provide a baseline of adolescent symptomatology prior to the emergence of PCC and provide important context for interpreting ongoing COVID symptoms. Data on PCC in adolescents should consider pre-pandemic symptom prevalence.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Population-Level Impact of Risk Factors on Stunting Among Children Under Five in Sub-Saharan Africa (2015-2022). 风险因素对撒哈拉以南非洲五岁以下儿童发育迟缓的人口层面影响（2015-2022年）。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-06-06 DOI: 10.1111/apa.70161

Handan Wand, Jayajothi Moodley, Sarita Naidoo, Vaneshree Govender

{"title":"Population-Level Impact of Risk Factors on Stunting Among Children Under Five in Sub-Saharan Africa (2015-2022).","authors":"Handan Wand, Jayajothi Moodley, Sarita Naidoo, Vaneshree Govender","doi":"10.1111/apa.70161","DOIUrl":"https://doi.org/10.1111/apa.70161","url":null,"abstract":"Aim: To identify the correlates of stunting and investigate their population-level impacts among children under 5 years in sub-Saharan Africa.Methods: Data from 179 572 children under five were included from nationally representative surveys conducted across 24 sub-Saharan African countries (2015-2022). Multivariable logistic regression models and population-level impacts of risk factors were estimated to highlight their contributions to stunting prevalence across the study regions.Results: Stunting prevalence ranged from 18% to 54%, with rates exceeding 50% in Burundi. Lack of basic household amenities was consistently associated with stunting, accounting for 24%-57% of cases across regions. Limited access to mass media further contributed to stunting rates, highlighting the role of education and awareness in preventing malnutrition. Maternal characteristics, such as lack of education and health insurance, were also significant risk factors, with adjusted odds ratios (aORs) ranging from 1.44 to 2.24.Conclusion: Socio-economic disparities are key risk factors for stunting in sub-Saharan Africa. These factors were statistically associated with a substantial proportion of stunting cases in high-prevalence regions. Targeted interventions to reduce inequalities, improve maternal education and expand essential services access are vital to achieving global nutrition targets, including the Sustainable Development Goal of reducing child stunting by 40% by 2025.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Motor Performance, Health-Related Quality of Life and Self-Esteem in Early Adolescence After Neonatal Therapeutic Hypothermia. 新生儿治疗性低温后青少年早期运动表现、健康相关生活质量和自尊

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-06-05 DOI: 10.1111/apa.70170

Mimmi Eriksson Westblad, Sari Kokkonen Nassef, Mats Blennow, Maria Jirwe, Katarina Lindström

{"title":"Motor Performance, Health-Related Quality of Life and Self-Esteem in Early Adolescence After Neonatal Therapeutic Hypothermia.","authors":"Mimmi Eriksson Westblad, Sari Kokkonen Nassef, Mats Blennow, Maria Jirwe, Katarina Lindström","doi":"10.1111/apa.70170","DOIUrl":"https://doi.org/10.1111/apa.70170","url":null,"abstract":"Aim: To explore the correlation between motor performance, health-related quality of life (HRQOL) and self-esteem in early adolescents treated with therapeutic hypothermia (TH) following neonatal hypoxic-ischaemic encephalopathy (HIE).Method: This cross-sectional study included 45 children (mean age 11 years) with a neonatal TH-treated HIE between 2007 and 2009 in Stockholm. Motor performance was assessed with Movement Assessment Battery for Children-2 (MABC-2), HRQOL by Paediatric Quality of Life Inventory (PedsQL 4.0) and self-esteem with 'I Think I Am -2'. Nonparametric statistical methods were applied.Results: Significant positive correlations were found between MABC-2 scores and all PedsQL 4.0 dimensions in parents' reports (p < 0.001-0.029). Parents reported lower PedsQL 4.0 Total scores for children below the 15th percentile on MABC-2 (p = 0.004), while the self-reports of the same children were not significant (p = 0.098). Motor performance did not affect children's self-esteem; no difference was found between the group above or the group below the 15th percentile (p = 0.881).Conclusion: Differences between parent and child-reported outcomes suggest the need for continued follow-up of children treated with TH into adolescence, including HRQOL and self-esteem. Long-term assessment is necessary to identify challenges not captured in early childhood or by self-reports alone.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0