Acta Paediatrica最新文献_第9页

Predicted Adult Height Remained Normal in Children With Premature Adrenarche Despite Advanced Bone Age. 预测的成人身高在患有肾上腺早衰的儿童中保持正常，尽管骨龄较高。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-07-28 DOI: 10.1111/apa.70252

Eetu Kanniainen, Jarmo Jääskeläinen, Jani Liimatta

{"title":"Predicted Adult Height Remained Normal in Children With Premature Adrenarche Despite Advanced Bone Age.","authors":"Eetu Kanniainen, Jarmo Jääskeläinen, Jani Liimatta","doi":"10.1111/apa.70252","DOIUrl":"https://doi.org/10.1111/apa.70252","url":null,"abstract":"Aim: Aetiological factors affecting the phenotype of adrenarche are largely unknown. This study investigated the phenotypic variability of premature adrenarche.Methods: In this cross-sectional retrospective registry study, data on 91 mainly Caucasian children diagnosed with premature adrenarche were retrieved from patient records. Hormonal and growth-related variables were analysed, and the data were further divided into subgroups to explore variations in different phenotypes of premature adrenarche.Results: We studied 91 children with premature adrenarche (23% boys) with median ages of 7.5 years (range 4.5-8.9) for boys and 6.8 years (4.3-8.0) for girls. They displayed increased height and weight, elevated androgen levels, and clinical signs of androgen action. Bone age was advanced by approximately 1 year, with overweight children showing more advanced bone age and linear growth. Adult heights predicted with bone age were comparable to mean parental heights. Girls with more advanced bone age had higher dehydroepiandrosterone sulfate (DHEAS) levels. Interestingly, early (< 6 years) diagnosed children exhibited higher height standard deviation scores but lower DHEAS levels compared to those diagnosed later (≥ 6 years).Conclusions: Despite advanced bone age, predicted adult heights remained normal in premature adrenarche. Subgroup differences suggested the heterogeneity of aetiological factors in premature adrenarche.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144735561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to: Meta-Analytical Choice Matters: How a Significant Result Becomes Nonsignificant Under Appropriate Modelling. 回应：元分析选择的重要性：一个重要的结果如何在适当的建模下变得不重要。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-07-28 DOI: 10.1111/apa.70257

Francisco Javier Gómez-Manzano, Esperanza Barroso-Corroto, José Alberto Laredo-Aguilera, Rosa María Molina-Madueño, Sergio Rodríguez-Cañamero, Juan Manuel Carmona-Torres

引用次数: 0

The Swedish Society of Paediatric Infectious Diseases' 2025 Recommendations for the Initial Management of Suspected Paediatric Sepsis With or Without Shock. 瑞典儿科传染病学会2025年关于伴有或不伴有休克的疑似儿科败血症初始治疗的建议。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-07-28 DOI: 10.1111/apa.70247

Annika Malmgren, Ioannis Orfanos, Johan Smedbäck, Karin Biswanger

引用次数: 0

Meta-Analytical Choices Matter: How a Significant Result Becomes Non-Significant Under Appropriate Modelling. 元分析选择的重要性：一个重要的结果如何在适当的建模下变得不重要。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-07-28 DOI: 10.1111/apa.70256

Javier Arredondo Montero

引用次数: 0

Urgent X-Rays in Children With Unexplained Haematemesis Help Rule Out Button Battery Ingestion. 不明原因呕血儿童的紧急x光检查有助于排除纽扣电池误食。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-07-26 DOI: 10.1111/apa.70244

Malni Irene, Marin Maura, Barbi Egidio, Amaddeo Alessandro

{"title":"Urgent X-Rays in Children With Unexplained Haematemesis Help Rule Out Button Battery Ingestion.","authors":"Malni Irene, Marin Maura, Barbi Egidio, Amaddeo Alessandro","doi":"10.1111/apa.70244","DOIUrl":"https://doi.org/10.1111/apa.70244","url":null,"abstract":"Aim: The ingestion of foreign bodies, particularly button batteries, is a significant concern in paediatric care, especially in children under 4 years of age. This study aims to review unwitnessed button battery ingestion in infants and toddlers, considering the serious complications and the higher risk in children under 2 years old.Method: A literature review was conducted on studies published between 1983 and 2025 using the terms 'disk battery', 'button battery', 'ingestion', and 'unwitnessed'. Fifteen studies were included, reporting a total of 41 cases of unwitnessed button battery ingestion.Results: The median age of patients was 18 months. Common symptoms included dysphagia, vomiting, fever, drooling and hematemesis. The average time to presentation at the emergency department was 72 h. Diagnostic delays were often due to initial misidentification of the battery as a coin. Radiographic imaging of the chest and abdomen identified the battery in 92% of cases, highlighting the diagnostic value of X-rays.Conclusion: Prompt chest and abdominal X-rays are recommended for children under 4 years presenting with unexplained hematemesis to rapidly identify button battery ingestion, minimise diagnostic delays and improve clinical outcomes.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144735564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Child Psychiatry and Child Neurology Need to Come Together. 儿童精神病学和儿童神经病学需要走到一起。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-07-25 DOI: 10.1111/apa.70254

Mary Coleman, Elisabeth Fernell, Maria Råstam, Helen Minnis, Christopher Gillberg

引用次数: 0

Maternal Oncological Disease and Congenital Pneumonia Are New Independent Risk Factors for Surfactant Requirements in Late Preterm Infants. 母亲肿瘤疾病和先天性肺炎是晚期早产儿表面活性剂需求的新独立危险因素。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-07-24 DOI: 10.1111/apa.70250

Simonetta Costa, Simona Fattore, Milena Tana, Giorgia Di Brina, Nicoletta Menzella, Paola Catalano, Benedetta De Santis, Chiara Barone, Giovanni Vento

{"title":"Maternal Oncological Disease and Congenital Pneumonia Are New Independent Risk Factors for Surfactant Requirements in Late Preterm Infants.","authors":"Simonetta Costa, Simona Fattore, Milena Tana, Giorgia Di Brina, Nicoletta Menzella, Paola Catalano, Benedetta De Santis, Chiara Barone, Giovanni Vento","doi":"10.1111/apa.70250","DOIUrl":"https://doi.org/10.1111/apa.70250","url":null,"abstract":"Aim: The purpose of this study was to evaluate the incidence of respiratory distress syndrome (RDS) in late preterm (LPT) infants. We also aimed to identify the risk factors associated with surfactant requirement and the clinical outcomes associated with surfactant therapy.Methods: We retrospectively analysed data from a single-centre neonatology unit at the Fondazione Policlinico Universitario Agostino Gemelli, IRCCS in Rome, Italy over a 4 year period. For each risk factor, the odds ratio (OR) and the 95% confidence interval (95% CI) were reported.Results: The incidence of RDS among 1335 LPT infants was 7.8%. The percentage of infants who required the surfactant was 3.4%. Gestational age (OR 0.541, 95% CI 0.367-0.796, p = 0.002), birth weight (OR 1.001, 95% CI 1.000-1.003; p = 0.037), 1 min Apgar score (OR 0.631, 95% CI 0.440-0.905, p = 0.012) and congenital pneumonia (OR 28.931, 95% CI 9.139-91.597, p < 0.001) were the neonatal risk factors associated with surfactant requirement. Oncological disease (OR 4.116, 95% CI 1.081-15.672, p = 0.038) was the maternal risk factor associated with surfactant requirement.Conclusions: Maternal oncological disease and congenital pneumonia emerged as new risk factors for surfactant requirement in LPT infants. These findings expanded the understanding of the mechanisms underlying RDS in LPT infants, moving beyond the known risk factors.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mobile Health Is a Cost-Effective Strategy for Managing Obesity in Adolescents: A Randomised Controlled Trial. 移动医疗是管理青少年肥胖的一种具有成本效益的策略：一项随机对照试验。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-07-24 DOI: 10.1111/apa.70248

Frantz Foissac, Géraldine Lepage, Nelly Briand, Marion Cosnefroy, Adrien Charrat, Myriam Dabbas

{"title":"Mobile Health Is a Cost-Effective Strategy for Managing Obesity in Adolescents: A Randomised Controlled Trial.","authors":"Frantz Foissac, Géraldine Lepage, Nelly Briand, Marion Cosnefroy, Adrien Charrat, Myriam Dabbas","doi":"10.1111/apa.70248","DOIUrl":"https://doi.org/10.1111/apa.70248","url":null,"abstract":"Aim: To compare the efficacy of remote monitoring versus traditional monitoring in reducing body mass index (BMI) in adolescents with obesity.Methods: Adolescents with obesity attending Necker Children's Hospital in Paris for the first time were enrolled in a randomised trial. After completing the three-month intervention, patients were randomised into two groups for the maintenance phase: a remote and a traditional monitoring group. The primary outcome was the proportion of participants achieving a BMI Z-score reduction > 0.5 standard deviation at 15 months. Secondary outcomes included attrition rate, child quality of life, and lifestyle factors.Results: Adolescents with severe obesity, a median age of 12 years, and a BMI Z-score of 3.95, were enrolled. No significant difference in the success rate was observed between remote (n = 38) and traditional (n = 40) groups (31.6% vs. 25.0%, p = 0.69). Failure was more likely in adolescents under 14 years and those with lower social quality of life scores. The remote group had significantly lower follow-up visits during the study (p < 0.0001).Conclusion: Mobile health interventions may be an effective alternative to traditional monitoring for reducing weight in adolescents with obesity during the maintenance phase while reducing the burden of clinic visits for parents and caregivers.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reported Experience of Family Violence in the New Zealand SUDI Case-Control Study. 新西兰SUDI病例对照研究中报告的家庭暴力经历。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-07-24 DOI: 10.1111/apa.70239

Dawn E Elder, John M D Thompson, Jess Wilson, Edwin A Mitchell

{"title":"Reported Experience of Family Violence in the New Zealand SUDI Case-Control Study.","authors":"Dawn E Elder, John M D Thompson, Jess Wilson, Edwin A Mitchell","doi":"10.1111/apa.70239","DOIUrl":"https://doi.org/10.1111/apa.70239","url":null,"abstract":"Aim: This study aimed to investigate the prevalence of family violence (FV) in sudden Unexpected Death in Infancy (SUDI) cases in New Zealand.Methods: A case-control study was implemented from March 2012 to February 2015. Cases comprised all SUDI deaths referred to the coroner. Controls were selected randomly, based on characteristics of previous SUDI deaths. The primary risk factor assessed was exposure to \"family violence ever\".Results: Of 258 controls, 248 (96.1%) had FV data and 73 (29.4%) had ever experienced FV. Among 132 SUDI cases, 58 (43.9%) had FV data and 35 (60.3%) had ever experienced FV. Adjusted risk factors associated with FV in controls included being in a de facto relationship, being single, mother's current partner not being the baby's biological father, maternal depression during pregnancy, and the number of previous pregnancies. In the multivariable model, FV was significantly associated with an increased risk of SUDI (OR 2.57 (95% CI 1.14, 5.81)).Conclusion: In this study, a history of FV was a significant risk factor for SUDI. Routine screening for FV exposure during perinatal and postnatal care is crucial, with appropriate support and referrals offered to affected families to potentially reduce SUDI risk.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to “Comment on ‘High Body Fat Level in Normal Weight Girls Is Related to Inflammation and Cardiometabolic Risk’” 回复“关于‘正常体重女孩的高体脂水平与炎症和心脏代谢风险有关’的评论”。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-07-24 DOI: 10.1111/apa.70249

Ariane Ribeiro de Freitas Rocha, Silvia Eloiza Priore

引用次数: 0